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Meenakshi Chatterjee

Publications and source records attributed to Meenakshi Chatterjee.

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Mobile Interaction for Assessing Fatigue, Sleep, and Activity in Neurodegenerative and Chronic Diseases

Fatigue, sleep, or disturbances in daily activities are common symptoms among patients with neurodegenerative disorders (NDD) and immune-mediated inflammatory diseases (IMID). The current assessment of such symptoms is usually conducted using patient reported outcomes (PROs) based on standardized questionnaires that patients usually complete every few months. This assessment protocol has raised some concerns, due to its propensity to exhibit biases derived from its subjectivity nature, or the low sensibility to changes, which may lead to a failure when trying to capture variability over time. In this work, we explore the use of smartphone data, which can serve as a proxy for how patients interact with their devices, to provide an effective, reliable, and objective assessment of the symptoms mentioned above. Our study comprises data from 137 participants belonging to 6 different disease groups, plus a healthy control group. We conducted statistical analysis based on repeated measures correlation, in which we analyze the correlation between screen-time and app-usage features with scores obtained from the PROs collected from the participants using a smartphone application.

cs.HC

Distributed Framework for Optimal Demand Distribution in Self-Balancing Microgrid

This study focusses on self-balancing microgrids to smartly utilize and prevent overdrawing of available power capacity of the grid. A distributed framework for automated distribution of optimal power demand is proposed, where all building in a microgrid dynamically and simultaneously adjusts their own power consumption to reach their individual optimal power demands while cooperatively striving to maintain the overall grid stable. Emphasis has been given to aspects of algorithm that yields lower time of convergence and is demonstrated through quantitative and qualitative analysis of simulation results.

eess.SY

Control Theoretic Approach to Predict Shock Response in Yeast

This report formulates a minimal model based on a control theoretic framework to best describe the dynamics of perfect adaptation shown by the hyper osmotic shock response system in yeast. Using principles from adaptive control and stability theory, we step by step apply system identification methods to build a simple second order linear system with only a few parameters, that can concisely model the High Osmolarity Glycerol (HOG) Mitogen Activated Protein Kinase (MAPK) signaling dynamics. Validation with experimental data demonstrate that the model is sufficient to predict response of yeast to an arbitrary external osmotic shock stimulus.

eess.SY