arXiv subjects

Mengfan Wang

Publications and source records attributed to Mengfan Wang.

3 recordsLinked to original sources

arXiv2026

Imaging Exploration of Molecular Subtypes in Tongue Squamous Cell Carcinoma

Tongue squamous cell carcinoma (TSCC) is an aggressive malignancy with marked biological heterogeneity and variable clinical outcomes. Although molecular profiling has improved understanding of TSCC heterogeneity, its clinical use remains constrained by invasive tissue sampling and limited representation of whole-tumor spatial complexity. Meanwhile, most radiomics studies in TSCC have focused on downstream clinical endpoints, and whether imaging can non-invasively reflect intrinsic molecular subtypes remains unclear. In this study, an integrated transcriptomic-radiomics framework was used to investigate the relationship between preoperative imaging phenotypes and molecular subtypes in TSCC. Transcriptomic data from 60 TSCC cases in The Cancer Genome Atlas were analyzed using unsupervised consensus clustering, followed by differential expression and functional enrichment analyses. Matched preoperative imaging data from The Cancer Imaging Archive were manually annotated for primary tumor regions, and radiomic features were extracted using PyRadiomics; group differences were assessed with the U-test. Two stable molecular subtypes, C1 and C2, were identified. Their biological differences were mainly associated with squamous epithelial differentiation, inflammatory signaling, and lipid metabolism, with C2 showing greater enrichment of immune-related pathways. In addition, 10 radiomic features differed significantly between the two subtypes, mainly wavelet-derived texture features from gray-level size zone, dependence, co-occurrence, and run length matrices (P=0.00202-0.0162). These findings support the potential of radiomics as a non-invasive approach for characterizing molecular heterogeneity in TSCC and provide an initial radiogenomic framework for biologically informed preoperative assessment.

q-bio.GN↗

arXiv2026

BinaryDemoire: Moiré-Aware Binarization for Image Demoiréing

Image demoiréing aims to remove structured moiré artifacts in recaptured imagery, where degradations are highly frequency-dependent and vary across scales and directions. While recent deep networks achieve high-quality restoration, their full-precision designs remain costly for deployment. Binarization offers an extreme compression regime by quantizing both activations and weights to 1-bit. Yet, it has been rarely studied for demoiréing and performs poorly when naively applied. In this work, we propose BinaryDemoire, a binarized demoiréing framework that explicitly accommodates the frequency structure of moiré degradations. First, we introduce a moiré-aware binary gate (MABG) that extracts lightweight frequency descriptors together with activation statistics. It predicts channel-wise gating coefficients to condition the aggregation of binary convolution responses. Second, we design a shuffle-grouped residual adapter (SGRA) that performs structured sparse shortcut alignment. It further integrates interleaved mixing to promote information exchange across different channel partitions. Extensive experiments on four benchmarks demonstrate that the proposed BinaryDemoire surpasses current binarization methods. Code: https://github.com/zhengchen1999/BinaryDemoire.

cs.CV↗

arXiv2025

QuantDemoire: Quantization with Outlier Aware for Image Demoiréing

Demoiréing aims to remove moiré artifacts that often occur in images. While recent deep learning-based methods have achieved promising results, they typically require substantial computational resources, limiting their deployment on edge devices. Model quantization offers a compelling solution. However, directly applying existing quantization methods to demoiréing models introduces severe performance degradation. The main reasons are distribution outliers and weakened representations in smooth regions. To address these issues, we propose QuantDemoire, a post-training quantization framework tailored to demoiréing. It contains two key components. **First}, we introduce an outlier-aware quantizer to reduce errors from outliers. It uses sampling-based range estimation to reduce activation outliers, and keeps a few extreme weights in FP16 with negligible cost. **Second**, we design a frequency-aware calibration strategy. It emphasizes low- and mid-frequency components during fine-tuning, which mitigates banding artifacts caused by low-bit quantization. Extensive experiments validate that our QuantDemoire achieves large reductions in parameters and computation while maintaining quality. Meanwhile, it outperforms existing quantization methods by over **4 dB** on W4A4. Code is released at: https://github.com/zhengchen1999/QuantDemoire.

cs.CV↗