arXiv subjects

Mengling Feng

Publications and source records attributed to Mengling Feng.

At least 55 records · Page 3Linked to original sources

arXiv2025

Towards accurate and reliable ICU outcome prediction: a multimodal learning framework based on belief function theory using structured EHRs and free-text notes

Accurate Intensive Care Unit (ICU) outcome prediction is critical for improving patient treatment quality and ICU resource allocation. Existing research mainly focuses on structured data, e.g. demographics and vital signs, and lacks effective frameworks to integrate clinical notes from heterogeneous electronic health records (EHRs). This study aims to explore a multimodal framework based on belief function theory that can effectively fuse heterogeneous structured EHRs and free-text notes for accurate and reliable ICU outcome prediction. The fusion strategy accounts for prediction uncertainty within each modality and conflicts between multimodal data. The experiments on MIMIC-III dataset show that our framework provides more accurate and reliable predictions than existing approaches. Specifically, it outperformed the best baseline by 1.05%/1.02% in BACC, 9.74%/6.04% in F1 score, 1.28%/0.9% in AUROC, and 6.21%/2.68% in AUPRC for predicting mortality and PLOS, respectively. Additionally, it improved the reliability of the predictions with a 26.8%/15.1% reduction in the Brier score and a 25.0%/13.3% reduction in negative log-likelihood. By effectively reducing false positives, the model can aid in better allocation of medical resources in the ICU. Furthermore, the proposed method is very versatile and can be extended to analyzing multimodal EHRs for other clinical tasks. The code implementation is available on https://github.com/yuchengruan/evid_multimodal_ehr.

cs.IT↗

arXiv2025

Self-supervised Quantized Representation for Seamlessly Integrating Knowledge Graphs with Large Language Models

Due to the presence of the natural gap between Knowledge Graph (KG) structures and the natural language, the effective integration of holistic structural information of KGs with Large Language Models (LLMs) has emerged as a significant question. To this end, we propose a two-stage framework to learn and apply quantized codes for each entity, aiming for the seamless integration of KGs with LLMs. Firstly, a self-supervised quantized representation (SSQR) method is proposed to compress both KG structural and semantic knowledge into discrete codes (\ie, tokens) that align the format of language sentences. We further design KG instruction-following data by viewing these learned codes as features to directly input to LLMs, thereby achieving seamless integration. The experiment results demonstrate that SSQR outperforms existing unsupervised quantized methods, producing more distinguishable codes. Further, the fine-tuned LLaMA2 and LLaMA3.1 also have superior performance on KG link prediction and triple classification tasks, utilizing only 16 tokens per entity instead of thousands in conventional prompting methods.

cs.CL↗

arXiv2025

A Survey of Large Language Models for Healthcare: from Data, Technology, and Applications to Accountability and Ethics

The utilization of large language models (LLMs) in the Healthcare domain has generated both excitement and concern due to their ability to effectively respond to freetext queries with certain professional knowledge. This survey outlines the capabilities of the currently developed LLMs for Healthcare and explicates their development process, with the aim of providing an overview of the development roadmap from traditional Pretrained Language Models (PLMs) to LLMs. Specifically, we first explore the potential of LLMs to enhance the efficiency and effectiveness of various Healthcare applications highlighting both the strengths and limitations. Secondly, we conduct a comparison between the previous PLMs and the latest LLMs, as well as comparing various LLMs with each other. Then we summarize related Healthcare training data, training methods, optimization strategies, and usage. Finally, the unique concerns associated with deploying LLMs in Healthcare settings are investigated, particularly regarding fairness, accountability, transparency and ethics. Our survey provide a comprehensive investigation from perspectives of both computer science and Healthcare specialty. Besides the discussion about Healthcare concerns, we supports the computer science community by compiling a collection of open source resources, such as accessible datasets, the latest methodologies, code implementations, and evaluation benchmarks in the Github. Summarily, we contend that a significant paradigm shift is underway, transitioning from PLMs to LLMs. This shift encompasses a move from discriminative AI approaches to generative AI approaches, as well as a shift from model-centered methodologies to data-centered methodologies. Also, we determine that the biggest obstacle of using LLMs in Healthcare are fairness, accountability, transparency and ethics.

cs.CL↗

arXiv2025

PAL: Prompting Analytic Learning with Missing Modality for Multi-Modal Class-Incremental Learning

Multi-modal class-incremental learning (MMCIL) seeks to leverage multi-modal data, such as audio-visual and image-text pairs, thereby enabling models to learn continuously across a sequence of tasks while mitigating forgetting. While existing studies primarily focus on the integration and utilization of multi-modal information for MMCIL, a critical challenge remains: the issue of missing modalities during incremental learning phases. This oversight can exacerbate severe forgetting and significantly impair model performance. To bridge this gap, we propose PAL, a novel exemplar-free framework tailored to MMCIL under missing-modality scenarios. Concretely, we devise modality-specific prompts to compensate for missing information, facilitating the model to maintain a holistic representation of the data. On this foundation, we reformulate the MMCIL problem into a Recursive Least-Squares task, delivering an analytical linear solution. Building upon these, PAL not only alleviates the inherent under-fitting limitation in analytic learning but also preserves the holistic representation of missing-modality data, achieving superior performance with less forgetting across various multi-modal incremental scenarios. Extensive experiments demonstrate that PAL significantly outperforms competitive methods across various datasets, including UPMC-Food101 and N24News, showcasing its robustness towards modality absence and its anti-forgetting ability to maintain high incremental accuracy.

cs.LG↗

arXiv2024

Evidential time-to-event prediction with calibrated uncertainty quantification

Time-to-event analysis provides insights into clinical prognosis and treatment recommendations. However, this task is more challenging than standard regression problems due to the presence of censored observations. Additionally, the lack of confidence assessment, model robustness, and prediction calibration raises concerns about the reliability of predictions. To address these challenges, we propose an evidential regression model specifically designed for time-to-event prediction. The proposed model quantifies both epistemic and aleatory uncertainties using Gaussian Random Fuzzy Numbers and belief functions, providing clinicians with uncertainty-aware survival time predictions. The model is trained by minimizing a generalized negative log-likelihood function accounting for data censoring. Experimental evaluations using simulated datasets with different data distributions and censoring conditions, as well as real-world datasets across diverse clinical applications, demonstrate that our model delivers both accurate and reliable performance, outperforming state-of-the-art methods. These results highlight the potential of our approach for enhancing clinical decision-making in survival analysis.

cs.LG↗

arXiv2024

EsurvFusion: An evidential multimodal survival fusion model based on Gaussian random fuzzy numbers

Multimodal survival analysis aims to combine heterogeneous data sources (e.g., clinical, imaging, text, genomics) to improve the prediction quality of survival outcomes. However, this task is particularly challenging due to high heterogeneity and noise across data sources, which vary in structure, distribution, and context. Additionally, the ground truth is often censored (uncertain) due to incomplete follow-up data. In this paper, we propose a novel evidential multimodal survival fusion model, EsurvFusion, designed to combine multimodal data at the decision level through an evidence-based decision fusion layer that jointly addresses both data and model uncertainty while incorporating modality-level reliability. Specifically, EsurvFusion first models unimodal data with newly introduced Gaussian random fuzzy numbers, producing unimodal survival predictions along with corresponding aleatoric and epistemic uncertainties. It then estimates modality-level reliability through a reliability discounting layer to correct the misleading impact of noisy data modalities. Finally, a multimodal evidence-based fusion layer is introduced to combine the discounted predictions to form a unified, interpretable multimodal survival analysis model, revealing each modality's influence based on the learned reliability coefficients. This is the first work that studies multimodal survival analysis with both uncertainty and reliability. Extensive experiments on four multimodal survival datasets demonstrate the effectiveness of our model in handling high heterogeneity data, establishing new state-of-the-art on several benchmarks.

cs.LG↗

arXiv2024

Teaching AI the Anatomy Behind the Scan: Addressing Anatomical Flaws in Medical Image Segmentation with Learnable Prior

Imposing key anatomical features, such as the number of organs, their shapes and relative positions, is crucial for building a robust multi-organ segmentation model. Current attempts to incorporate anatomical features include broadening the effective receptive field (ERF) size with data-intensive modules, or introducing anatomical constraints that scales poorly to multi-organ segmentation. We introduce a novel architecture called the Anatomy-Informed Cascaded Segmentation Network (AIC-Net). AIC-Net incorporates a learnable input termed "Anatomical Prior", which can be adapted to patient-specific anatomy using a differentiable spatial deformation. The deformed prior later guides decoder layers towards more anatomy-informed predictions. We repeat this process at a local patch level to enhance the representation of intricate objects, resulting in a cascaded network structure. AIC-Net is a general method that enhances any existing segmentation models to be more anatomy-aware. We have validated the performance of AIC-Net, with various backbones, on two multi-organ segmentation tasks: abdominal organs and vertebrae. For each respective task, our benchmarks demonstrate improved dice score and Hausdorff distance.

cs.CV↗

arXiv2024

Has Multimodal Learning Delivered Universal Intelligence in Healthcare? A Comprehensive Survey

The rapid development of artificial intelligence has constantly reshaped the field of intelligent healthcare and medicine. As a vital technology, multimodal learning has increasingly garnered interest due to data complementarity, comprehensive modeling form, and great application potential. Currently, numerous researchers are dedicating their attention to this field, conducting extensive studies and constructing abundant intelligent systems. Naturally, an open question arises that has multimodal learning delivered universal intelligence in healthcare? To answer the question, we adopt three unique viewpoints for a holistic analysis. Firstly, we conduct a comprehensive survey of the current progress of medical multimodal learning from the perspectives of datasets, task-oriented methods, and universal foundation models. Based on them, we further discuss the proposed question from five issues to explore the real impacts of advanced techniques in healthcare, from data and technologies to performance and ethics. The answer is that current technologies have NOT achieved universal intelligence and there remains a significant journey to undertake. Finally, in light of the above reviews and discussions, we point out ten potential directions for exploration towards the goal of universal intelligence in healthcare.

cs.AI↗

arXiv2024

Language Modeling on Tabular Data: A Survey of Foundations, Techniques and Evolution

Tabular data, a prevalent data type across various domains, presents unique challenges due to its heterogeneous nature and complex structural relationships. Achieving high predictive performance and robustness in tabular data analysis holds significant promise for numerous applications. Influenced by recent advancements in natural language processing, particularly transformer architectures, new methods for tabular data modeling have emerged. Early techniques concentrated on pre-training transformers from scratch, often encountering scalability issues. Subsequently, methods leveraging pre-trained language models like BERT have been developed, which require less data and yield enhanced performance. The recent advent of large language models, such as GPT and LLaMA, has further revolutionized the field, facilitating more advanced and diverse applications with minimal fine-tuning. Despite the growing interest, a comprehensive survey of language modeling techniques for tabular data remains absent. This paper fills this gap by providing a systematic review of the development of language modeling for tabular data, encompassing: (1) a categorization of different tabular data structures and data types; (2) a review of key datasets used in model training and tasks used for evaluation; (3) a summary of modeling techniques including widely-adopted data processing methods, popular architectures, and training objectives; (4) the evolution from adapting traditional Pre-training/Pre-trained language models to the utilization of large language models; (5) an identification of persistent challenges and potential future research directions in language modeling for tabular data analysis. GitHub page associated with this survey is available at: https://github.com/lanxiang1017/Language-Modeling-on-Tabular-Data-Survey.git.

cs.CL↗

arXiv2024

Learning the Unlearned: Mitigating Feature Suppression in Contrastive Learning

Self-Supervised Contrastive Learning has proven effective in deriving high-quality representations from unlabeled data. However, a major challenge that hinders both unimodal and multimodal contrastive learning is feature suppression, a phenomenon where the trained model captures only a limited portion of the information from the input data while overlooking other potentially valuable content. This issue often leads to indistinguishable representations for visually similar but semantically different inputs, adversely affecting downstream task performance, particularly those requiring rigorous semantic comprehension. To address this challenge, we propose a novel model-agnostic Multistage Contrastive Learning (MCL) framework. Unlike standard contrastive learning which inherently captures one single biased feature distribution, MCL progressively learns previously unlearned features through feature-aware negative sampling at each stage, where the negative samples of an anchor are exclusively selected from the cluster it was assigned to in preceding stages. Meanwhile, MCL preserves the previously well-learned features by cross-stage representation integration, integrating features across all stages to form final representations. Our comprehensive evaluation demonstrates MCL's effectiveness and superiority across both unimodal and multimodal contrastive learning, spanning a range of model architectures from ResNet to Vision Transformers (ViT). Remarkably, in tasks where the original CLIP model has shown limitations, MCL dramatically enhances performance, with improvements up to threefold on specific attributes in the recently proposed MMVP benchmark.

cs.CV↗

arXiv2024

An evidential time-to-event prediction model based on Gaussian random fuzzy numbers

We introduce an evidential model for time-to-event prediction with censored data. In this model, uncertainty on event time is quantified by Gaussian random fuzzy numbers, a newly introduced family of random fuzzy subsets of the real line with associated belief functions, generalizing both Gaussian random variables and Gaussian possibility distributions. Our approach makes minimal assumptions about the underlying time-to-event distribution. The model is fit by minimizing a generalized negative log-likelihood function that accounts for both normal and censored data. Comparative experiments on two real-world datasets demonstrate the very good performance of our model as compared to the state-of-the-art.

cs.LG↗

arXiv2024

Towards Enhancing Time Series Contrastive Learning: A Dynamic Bad Pair Mining Approach

Not all positive pairs are beneficial to time series contrastive learning. In this paper, we study two types of bad positive pairs that can impair the quality of time series representation learned through contrastive learning: the noisy positive pair and the faulty positive pair. We observe that, with the presence of noisy positive pairs, the model tends to simply learn the pattern of noise (Noisy Alignment). Meanwhile, when faulty positive pairs arise, the model wastes considerable amount of effort aligning non-representative patterns (Faulty Alignment). To address this problem, we propose a Dynamic Bad Pair Mining (DBPM) algorithm, which reliably identifies and suppresses bad positive pairs in time series contrastive learning. Specifically, DBPM utilizes a memory module to dynamically track the training behavior of each positive pair along training process. This allows us to identify potential bad positive pairs at each epoch based on their historical training behaviors. The identified bad pairs are subsequently down-weighted through a transformation module, thereby mitigating their negative impact on the representation learning process. DBPM is a simple algorithm designed as a lightweight plug-in without learnable parameters to enhance the performance of existing state-of-the-art methods. Through extensive experiments conducted on four large-scale, real-world time series datasets, we demonstrate DBPM's efficacy in mitigating the adverse effects of bad positive pairs.

cs.LG↗

arXiv2023

The NUS-HLT System for ICASSP2024 ICMC-ASR Grand Challenge

This paper summarizes our team's efforts in both tracks of the ICMC-ASR Challenge for in-car multi-channel automatic speech recognition. Our submitted systems for ICMC-ASR Challenge include the multi-channel front-end enhancement and diarization, training data augmentation, speech recognition modeling with multi-channel branches. Tested on the offical Eval1 and Eval2 set, our best system achieves a relative 34.3% improvement in CER and 56.5% improvement in cpCER, compared to the offical baseline system.

eess.AS↗

arXiv2023

Selective HuBERT: Self-Supervised Pre-Training for Target Speaker in Clean and Mixture Speech

Self-supervised pre-trained speech models were shown effective for various downstream speech processing tasks. Since they are mainly pre-trained to map input speech to pseudo-labels, the resulting representations are only effective for the type of pre-train data used, either clean or mixture speech. With the idea of selective auditory attention, we propose a novel pre-training solution called Selective-HuBERT, or SHuBERT, which learns the selective extraction of target speech representations from either clean or mixture speech. Specifically, SHuBERT is trained to predict pseudo labels of a target speaker, conditioned on an enrolled speech from the target speaker. By doing so, SHuBERT is expected to selectively attend to the target speaker in a complex acoustic environment, thus benefiting various downstream tasks. We further introduce a dual-path training strategy and use the cross-correlation constraint between the two branches to encourage the model to generate noise-invariant representation. Experiments on SUPERB benchmark and LibriMix dataset demonstrate the universality and noise-robustness of SHuBERT. Furthermore, we find that our high-quality representation can be easily integrated with conventional supervised learning methods to achieve significant performance, even under extremely low-resource labeled data.

eess.AS↗

arXiv2023

A review of uncertainty quantification in medical image analysis: probabilistic and non-probabilistic methods

The comprehensive integration of machine learning healthcare models within clinical practice remains suboptimal, notwithstanding the proliferation of high-performing solutions reported in the literature. A predominant factor hindering widespread adoption pertains to an insufficiency of evidence affirming the reliability of the aforementioned models. Recently, uncertainty quantification methods have been proposed as a potential solution to quantify the reliability of machine learning models and thus increase the interpretability and acceptability of the result. In this review, we offer a comprehensive overview of prevailing methods proposed to quantify uncertainty inherent in machine learning models developed for various medical image tasks. Contrary to earlier reviews that exclusively focused on probabilistic methods, this review also explores non-probabilistic approaches, thereby furnishing a more holistic survey of research pertaining to uncertainty quantification for machine learning models. Analysis of medical images with the summary and discussion on medical applications and the corresponding uncertainty evaluation protocols are presented, which focus on the specific challenges of uncertainty in medical image analysis. We also highlight some potential future research work at the end. Generally, this review aims to allow researchers from both clinical and technical backgrounds to gain a quick and yet in-depth understanding of the research in uncertainty quantification for medical image analysis machine learning models.

eess.IV↗

arXiv2022

FCSN: Global Context Aware Segmentation by Learning the Fourier Coefficients of Objects in Medical Images

The encoder-decoder model is a commonly used Deep Neural Network (DNN) model for medical image segmentation. Conventional encoder-decoder models make pixel-wise predictions focusing heavily on local patterns around the pixel. This makes it challenging to give segmentation that preserves the object's shape and topology, which often requires an understanding of the global context of the object. In this work, we propose a Fourier Coefficient Segmentation Network~(FCSN) -- a novel DNN-based model that segments an object by learning the complex Fourier coefficients of the object's masks. The Fourier coefficients are calculated by integrating over the whole contour. Therefore, for our model to make a precise estimation of the coefficients, the model is motivated to incorporate the global context of the object, leading to a more accurate segmentation of the object's shape. This global context awareness also makes our model robust to unseen local perturbations during inference, such as additive noise or motion blur that are prevalent in medical images. When FCSN is compared with other state-of-the-art models (UNet+, DeepLabV3+, UNETR) on 3 medical image segmentation tasks (ISIC\_2018, RIM\_CUP, RIM\_DISC), FCSN attains significantly lower Hausdorff scores of 19.14 (6\%), 17.42 (6\%), and 9.16 (14\%) on the 3 tasks, respectively. Moreover, FCSN is lightweight by discarding the decoder module, which incurs significant computational overhead. FCSN only requires 22.2M parameters, 82M and 10M fewer parameters than UNETR and DeepLabV3+. FCSN attains inference and training speeds of 1.6ms/img and 6.3ms/img, that is 8$\times$ and 3$\times$ faster than UNet and UNETR.

eess.IV↗

arXiv2022

UFRC: A Unified Framework for Reliable COVID-19 Detection on Crowdsourced Cough Audio

We suggested a unified system with core components of data augmentation, ImageNet-pretrained ResNet-50, cost-sensitive loss, deep ensemble learning, and uncertainty estimation to quickly and consistently detect COVID-19 using acoustic evidence. To increase the model's capacity to identify a minority class, data augmentation and cost-sensitive loss are incorporated (infected samples). In the COVID-19 detection challenge, ImageNet-pretrained ResNet-50 has been found to be effective. The unified framework also integrates deep ensemble learning and uncertainty estimation to integrate predictions from various base classifiers for generalisation and reliability. We ran a series of tests using the DiCOVA2021 challenge dataset to assess the efficacy of our proposed method, and the results show that our method has an AUC-ROC of 85.43 percent, making it a promising method for COVID-19 detection. The unified framework also demonstrates that audio may be used to quickly diagnose different respiratory disorders.

cs.SD↗

arXiv2022

DiCOVA-Net: Diagnosing COVID-19 using Acoustics based on Deep Residual Network for the DiCOVA Challenge 2021

In this paper, we propose a deep residual network-based method, namely the DiCOVA-Net, to identify COVID-19 infected patients based on the acoustic recording of their coughs. Since there are far more healthy people than infected patients, this classification problem faces the challenge of imbalanced data. To improve the model's ability to recognize minority class (the infected patients), we introduce data augmentation and cost-sensitive methods into our model. Besides, considering the particularity of this task, we deploy some fine-tuning techniques to adjust the pre-training ResNet50. Furthermore, to improve the model's generalizability, we use ensemble learning to integrate prediction results from multiple base classifiers generated using different random seeds. To evaluate the proposed DiCOVA-Net's performance, we conducted experiments with the DiCOVA challenge dataset. The results show that our method has achieved 85.43\% in AUC, among the top of all competing teams.

cs.SD↗