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Mengya Xu

Publications and source records attributed to Mengya Xu.

36 records · Page 2Linked to original sources

PitVQA: Image-grounded Text Embedding LLM for Visual Question Answering in Pituitary Surgery

Visual Question Answering (VQA) within the surgical domain, utilizing Large Language Models (LLMs), offers a distinct opportunity to improve intra-operative decision-making and facilitate intuitive surgeon-AI interaction. However, the development of LLMs for surgical VQA is hindered by the scarcity of diverse and extensive datasets with complex reasoning tasks. Moreover, contextual fusion of the image and text modalities remains an open research challenge due to the inherent differences between these two types of information and the complexity involved in aligning them. This paper introduces PitVQA, a novel dataset specifically designed for VQA in endonasal pituitary surgery and PitVQA-Net, an adaptation of the GPT2 with a novel image-grounded text embedding for surgical VQA. PitVQA comprises 25 procedural videos and a rich collection of question-answer pairs spanning crucial surgical aspects such as phase and step recognition, context understanding, tool detection and localization, and tool-tissue interactions. PitVQA-Net consists of a novel image-grounded text embedding that projects image and text features into a shared embedding space and GPT2 Backbone with an excitation block classification head to generate contextually relevant answers within the complex domain of endonasal pituitary surgery. Our image-grounded text embedding leverages joint embedding, cross-attention and contextual representation to understand the contextual relationship between questions and surgical images. We demonstrate the effectiveness of PitVQA-Net on both the PitVQA and the publicly available EndoVis18-VQA dataset, achieving improvements in balanced accuracy of 8% and 9% over the most recent baselines, respectively. Our code and dataset is available at https://github.com/mobarakol/PitVQA.

cs.CV↗

Endo-4DGS: Endoscopic Monocular Scene Reconstruction with 4D Gaussian Splatting

In the realm of robot-assisted minimally invasive surgery, dynamic scene reconstruction can significantly enhance downstream tasks and improve surgical outcomes. Neural Radiance Fields (NeRF)-based methods have recently risen to prominence for their exceptional ability to reconstruct scenes but are hampered by slow inference speed, prolonged training, and inconsistent depth estimation. Some previous work utilizes ground truth depth for optimization but is hard to acquire in the surgical domain. To overcome these obstacles, we present Endo-4DGS, a real-time endoscopic dynamic reconstruction approach that utilizes 3D Gaussian Splatting (GS) for 3D representation. Specifically, we propose lightweight MLPs to capture temporal dynamics with Gaussian deformation fields. To obtain a satisfactory Gaussian Initialization, we exploit a powerful depth estimation foundation model, Depth-Anything, to generate pseudo-depth maps as a geometry prior. We additionally propose confidence-guided learning to tackle the ill-pose problems in monocular depth estimation and enhance the depth-guided reconstruction with surface normal constraints and depth regularization. Our approach has been validated on two surgical datasets, where it can effectively render in real-time, compute efficiently, and reconstruct with remarkable accuracy.

cs.CV↗

An Efficient MLP-based Point-guided Segmentation Network for Ore Images with Ambiguous Boundary

The precise segmentation of ore images is critical to the successful execution of the beneficiation process. Due to the homogeneous appearance of the ores, which leads to low contrast and unclear boundaries, accurate segmentation becomes challenging, and recognition becomes problematic. This paper proposes a lightweight framework based on Multi-Layer Perceptron (MLP), which focuses on solving the problem of edge burring. Specifically, we introduce a lightweight backbone better suited for efficiently extracting low-level features. Besides, we design a feature pyramid network consisting of two MLP structures that balance local and global information thus enhancing detection accuracy. Furthermore, we propose a novel loss function that guides the prediction points to match the instance edge points to achieve clear object boundaries. We have conducted extensive experiments to validate the efficacy of our proposed method. Our approach achieves a remarkable processing speed of over 27 frames per second (FPS) with a model size of only 73 MB. Moreover, our method delivers a consistently high level of accuracy, with impressive performance scores of 60.4 and 48.9 in~$AP_{50}^{box}$ and~$AP_{50}^{mask}$ respectively, as compared to the currently available state-of-the-art techniques, when tested on the ore image dataset. The source code will be released at \url{https://github.com/MVME-HBUT/ORENEXT}.

cs.CV↗

Privacy-Preserving Synthetic Continual Semantic Segmentation for Robotic Surgery

Deep Neural Networks (DNNs) based semantic segmentation of the robotic instruments and tissues can enhance the precision of surgical activities in robot-assisted surgery. However, in biological learning, DNNs cannot learn incremental tasks over time and exhibit catastrophic forgetting, which refers to the sharp decline in performance on previously learned tasks after learning a new one. Specifically, when data scarcity is the issue, the model shows a rapid drop in performance on previously learned instruments after learning new data with new instruments. The problem becomes worse when it limits releasing the dataset of the old instruments for the old model due to privacy concerns and the unavailability of the data for the new or updated version of the instruments for the continual learning model. For this purpose, we develop a privacy-preserving synthetic continual semantic segmentation framework by blending and harmonizing (i) open-source old instruments foreground to the synthesized background without revealing real patient data in public and (ii) new instruments foreground to extensively augmented real background. To boost the balanced logit distillation from the old model to the continual learning model, we design overlapping class-aware temperature normalization (CAT) by controlling model learning utility. We also introduce multi-scale shifted-feature distillation (SD) to maintain long and short-range spatial relationships among the semantic objects where conventional short-range spatial features with limited information reduce the power of feature distillation. We demonstrate the effectiveness of our framework on the EndoVis 2017 and 2018 instrument segmentation dataset with a generalized continual learning setting. Code is available at~\url{https://github.com/XuMengyaAmy/Synthetic_CAT_SD}.

cs.CV↗

SAR-RARP50: Segmentation of surgical instrumentation and Action Recognition on Robot-Assisted Radical Prostatectomy Challenge

Surgical tool segmentation and action recognition are fundamental building blocks in many computer-assisted intervention applications, ranging from surgical skills assessment to decision support systems. Nowadays, learning-based action recognition and segmentation approaches outperform classical methods, relying, however, on large, annotated datasets. Furthermore, action recognition and tool segmentation algorithms are often trained and make predictions in isolation from each other, without exploiting potential cross-task relationships. With the EndoVis 2022 SAR-RARP50 challenge, we release the first multimodal, publicly available, in-vivo, dataset for surgical action recognition and semantic instrumentation segmentation, containing 50 suturing video segments of Robotic Assisted Radical Prostatectomy (RARP). The aim of the challenge is twofold. First, to enable researchers to leverage the scale of the provided dataset and develop robust and highly accurate single-task action recognition and tool segmentation approaches in the surgical domain. Second, to further explore the potential of multitask-based learning approaches and determine their comparative advantage against their single-task counterparts. A total of 12 teams participated in the challenge, contributing 7 action recognition methods, 9 instrument segmentation techniques, and 4 multitask approaches that integrated both action recognition and instrument segmentation. The complete SAR-RARP50 dataset is available at: https://rdr.ucl.ac.uk/projects/SARRARP50_Segmentation_of_surgical_instrumentation_and_Action_Recognition_on_Robot-Assisted_Radical_Prostatectomy_Challenge/191091

cs.CV↗

SAM Meets Robotic Surgery: An Empirical Study on Generalization, Robustness and Adaptation

The Segment Anything Model (SAM) serves as a fundamental model for semantic segmentation and demonstrates remarkable generalization capabilities across a wide range of downstream scenarios. In this empirical study, we examine SAM's robustness and zero-shot generalizability in the field of robotic surgery. We comprehensively explore different scenarios, including prompted and unprompted situations, bounding box and points-based prompt approaches, as well as the ability to generalize under corruptions and perturbations at five severity levels. Additionally, we compare the performance of SAM with state-of-the-art supervised models. We conduct all the experiments with two well-known robotic instrument segmentation datasets from MICCAI EndoVis 2017 and 2018 challenges. Our extensive evaluation results reveal that although SAM shows remarkable zero-shot generalization ability with bounding box prompts, it struggles to segment the whole instrument with point-based prompts and unprompted settings. Furthermore, our qualitative figures demonstrate that the model either failed to predict certain parts of the instrument mask (e.g., jaws, wrist) or predicted parts of the instrument as wrong classes in the scenario of overlapping instruments within the same bounding box or with the point-based prompt. In fact, SAM struggles to identify instruments in complex surgical scenarios characterized by the presence of blood, reflection, blur, and shade. Additionally, SAM is insufficiently robust to maintain high performance when subjected to various forms of data corruption. We also attempt to fine-tune SAM using Low-rank Adaptation (LoRA) and propose SurgicalSAM, which shows the capability in class-wise mask prediction without prompt. Therefore, we can argue that, without further domain-specific fine-tuning, SAM is not ready for downstream surgical tasks.

eess.IV↗

Rectifying Noisy Labels with Sequential Prior: Multi-Scale Temporal Feature Affinity Learning for Robust Video Segmentation

Noisy label problems are inevitably in existence within medical image segmentation causing severe performance degradation. Previous segmentation methods for noisy label problems only utilize a single image while the potential of leveraging the correlation between images has been overlooked. Especially for video segmentation, adjacent frames contain rich contextual information beneficial in cognizing noisy labels. Based on two insights, we propose a Multi-Scale Temporal Feature Affinity Learning (MS-TFAL) framework to resolve noisy-labeled medical video segmentation issues. First, we argue the sequential prior of videos is an effective reference, i.e., pixel-level features from adjacent frames are close in distance for the same class and far in distance otherwise. Therefore, Temporal Feature Affinity Learning (TFAL) is devised to indicate possible noisy labels by evaluating the affinity between pixels in two adjacent frames. We also notice that the noise distribution exhibits considerable variations across video, image, and pixel levels. In this way, we introduce Multi-Scale Supervision (MSS) to supervise the network from three different perspectives by re-weighting and refining the samples. This design enables the network to concentrate on clean samples in a coarse-to-fine manner. Experiments with both synthetic and real-world label noise demonstrate that our method outperforms recent state-of-the-art robust segmentation approaches. Code is available at https://github.com/BeileiCui/MS-TFAL.

cs.CV↗

Generalizing Surgical Instruments Segmentation to Unseen Domains with One-to-Many Synthesis

Despite their impressive performance in various surgical scene understanding tasks, deep learning-based methods are frequently hindered from deploying to real-world surgical applications for various causes. Particularly, data collection, annotation, and domain shift in-between sites and patients are the most common obstacles. In this work, we mitigate data-related issues by efficiently leveraging minimal source images to generate synthetic surgical instrument segmentation datasets and achieve outstanding generalization performance on unseen real domains. Specifically, in our framework, only one background tissue image and at most three images of each foreground instrument are taken as the seed images. These source images are extensively transformed and employed to build up the foreground and background image pools, from which randomly sampled tissue and instrument images are composed with multiple blending techniques to generate new surgical scene images. Besides, we introduce hybrid training-time augmentations to diversify the training data further. Extensive evaluation on three real-world datasets, i.e., Endo2017, Endo2018, and RoboTool, demonstrates that our one-to-many synthetic surgical instruments datasets generation and segmentation framework can achieve encouraging performance compared with training with real data. Notably, on the RoboTool dataset, where a more significant domain gap exists, our framework shows its superiority of generalization by a considerable margin. We expect that our inspiring results will attract research attention to improving model generalization with data synthesizing.

eess.IV↗

Curriculum-Based Augmented Fourier Domain Adaptation for Robust Medical Image Segmentation

Accurate and robust medical image segmentation is fundamental and crucial for enhancing the autonomy of computer-aided diagnosis and intervention systems. Medical data collection normally involves different scanners, protocols, and populations, making domain adaptation (DA) a highly demanding research field to alleviate model degradation in the deployment site. To preserve the model performance across multiple testing domains, this work proposes the Curriculum-based Augmented Fourier Domain Adaptation (Curri-AFDA) for robust medical image segmentation. In particular, our curriculum learning strategy is based on the causal relationship of a model under different levels of data shift in the deployment phase, where the higher the shift is, the harder to recognize the variance. Considering this, we progressively introduce more amplitude information from the target domain to the source domain in the frequency space during the curriculum-style training to smoothly schedule the semantic knowledge transfer in an easier-to-harder manner. Besides, we incorporate the training-time chained augmentation mixing to help expand the data distributions while preserving the domain-invariant semantics, which is beneficial for the acquired model to be more robust and generalize better to unseen domains. Extensive experiments on two segmentation tasks of Retina and Nuclei collected from multiple sites and scanners suggest that our proposed method yields superior adaptation and generalization performance. Meanwhile, our approach proves to be more robust under various corruption types and increasing severity levels. In addition, we show our method is also beneficial in the domain-adaptive classification task with skin lesion datasets. The code is available at https://github.com/lofrienger/Curri-AFDA.

eess.IV↗

S$^2$ME: Spatial-Spectral Mutual Teaching and Ensemble Learning for Scribble-supervised Polyp Segmentation

Fully-supervised polyp segmentation has accomplished significant triumphs over the years in advancing the early diagnosis of colorectal cancer. However, label-efficient solutions from weak supervision like scribbles are rarely explored yet primarily meaningful and demanding in medical practice due to the expensiveness and scarcity of densely-annotated polyp data. Besides, various deployment issues, including data shifts and corruption, put forward further requests for model generalization and robustness. To address these concerns, we design a framework of Spatial-Spectral Dual-branch Mutual Teaching and Entropy-guided Pseudo Label Ensemble Learning (S$^2$ME). Concretely, for the first time in weakly-supervised medical image segmentation, we promote the dual-branch co-teaching framework by leveraging the intrinsic complementarity of features extracted from the spatial and spectral domains and encouraging cross-space consistency through collaborative optimization. Furthermore, to produce reliable mixed pseudo labels, which enhance the effectiveness of ensemble learning, we introduce a novel adaptive pixel-wise fusion technique based on the entropy guidance from the spatial and spectral branches. Our strategy efficiently mitigates the deleterious effects of uncertainty and noise present in pseudo labels and surpasses previous alternatives in terms of efficacy. Ultimately, we formulate a holistic optimization objective to learn from the hybrid supervision of scribbles and pseudo labels. Extensive experiments and evaluation on four public datasets demonstrate the superiority of our method regarding in-distribution accuracy, out-of-distribution generalization, and robustness, highlighting its promising clinical significance. Our code is available at https://github.com/lofrienger/S2ME.

eess.IV↗

SAM Meets Robotic Surgery: An Empirical Study in Robustness Perspective

Segment Anything Model (SAM) is a foundation model for semantic segmentation and shows excellent generalization capability with the prompts. In this empirical study, we investigate the robustness and zero-shot generalizability of the SAM in the domain of robotic surgery in various settings of (i) prompted vs. unprompted; (ii) bounding box vs. points-based prompt; (iii) generalization under corruptions and perturbations with five severity levels; and (iv) state-of-the-art supervised model vs. SAM. We conduct all the observations with two well-known robotic instrument segmentation datasets of MICCAI EndoVis 2017 and 2018 challenges. Our extensive evaluation results reveal that although SAM shows remarkable zero-shot generalization ability with bounding box prompts, it struggles to segment the whole instrument with point-based prompts and unprompted settings. Furthermore, our qualitative figures demonstrate that the model either failed to predict the parts of the instrument mask (e.g., jaws, wrist) or predicted parts of the instrument as different classes in the scenario of overlapping instruments within the same bounding box or with the point-based prompt. In fact, it is unable to identify instruments in some complex surgical scenarios of blood, reflection, blur, and shade. Additionally, SAM is insufficiently robust to maintain high performance when subjected to various forms of data corruption. Therefore, we can argue that SAM is not ready for downstream surgical tasks without further domain-specific fine-tuning.

eess.IV↗

CholecTriplet2021: A benchmark challenge for surgical action triplet recognition

Context-aware decision support in the operating room can foster surgical safety and efficiency by leveraging real-time feedback from surgical workflow analysis. Most existing works recognize surgical activities at a coarse-grained level, such as phases, steps or events, leaving out fine-grained interaction details about the surgical activity; yet those are needed for more helpful AI assistance in the operating room. Recognizing surgical actions as triplets of combination delivers comprehensive details about the activities taking place in surgical videos. This paper presents CholecTriplet2021: an endoscopic vision challenge organized at MICCAI 2021 for the recognition of surgical action triplets in laparoscopic videos. The challenge granted private access to the large-scale CholecT50 dataset, which is annotated with action triplet information. In this paper, we present the challenge setup and assessment of the state-of-the-art deep learning methods proposed by the participants during the challenge. A total of 4 baseline methods from the challenge organizers and 19 new deep learning algorithms by competing teams are presented to recognize surgical action triplets directly from surgical videos, achieving mean average precision (mAP) ranging from 4.2% to 38.1%. This study also analyzes the significance of the results obtained by the presented approaches, performs a thorough methodological comparison between them, in-depth result analysis, and proposes a novel ensemble method for enhanced recognition. Our analysis shows that surgical workflow analysis is not yet solved, and also highlights interesting directions for future research on fine-grained surgical activity recognition which is of utmost importance for the development of AI in surgery.

cs.CV↗

Confidence-Aware Paced-Curriculum Learning by Label Smoothing for Surgical Scene Understanding

Curriculum learning and self-paced learning are the training strategies that gradually feed the samples from easy to more complex. They have captivated increasing attention due to their excellent performance in robotic vision. Most recent works focus on designing curricula based on difficulty levels in input samples or smoothing the feature maps. However, smoothing labels to control the learning utility in a curriculum manner is still unexplored. In this work, we design a paced curriculum by label smoothing (P-CBLS) using paced learning with uniform label smoothing (ULS) for classification tasks and fuse uniform and spatially varying label smoothing (SVLS) for semantic segmentation tasks in a curriculum manner. In ULS and SVLS, a bigger smoothing factor value enforces a heavy smoothing penalty in the true label and limits learning less information. Therefore, we design the curriculum by label smoothing (CBLS). We set a bigger smoothing value at the beginning of training and gradually decreased it to zero to control the model learning utility from lower to higher. We also designed a confidence-aware pacing function and combined it with our CBLS to investigate the benefits of various curricula. The proposed techniques are validated on four robotic surgery datasets of multi-class, multi-label classification, captioning, and segmentation tasks. We also investigate the robustness of our method by corrupting validation data into different severity levels. Our extensive analysis shows that the proposed method improves prediction accuracy and robustness.

cs.CV↗

Task-Aware Asynchronous Multi-Task Model with Class Incremental Contrastive Learning for Surgical Scene Understanding

Purpose: Surgery scene understanding with tool-tissue interaction recognition and automatic report generation can play an important role in intra-operative guidance, decision-making and postoperative analysis in robotic surgery. However, domain shifts between different surgeries with inter and intra-patient variation and novel instruments' appearance degrade the performance of model prediction. Moreover, it requires output from multiple models, which can be computationally expensive and affect real-time performance. Methodology: A multi-task learning (MTL) model is proposed for surgical report generation and tool-tissue interaction prediction that deals with domain shift problems. The model forms of shared feature extractor, mesh-transformer branch for captioning and graph attention branch for tool-tissue interaction prediction. The shared feature extractor employs class incremental contrastive learning (CICL) to tackle intensity shift and novel class appearance in the target domain. We design Laplacian of Gaussian (LoG) based curriculum learning into both shared and task-specific branches to enhance model learning. We incorporate a task-aware asynchronous MTL optimization technique to fine-tune the shared weights and converge both tasks optimally. Results: The proposed MTL model trained using task-aware optimization and fine-tuning techniques reported a balanced performance (BLEU score of 0.4049 for scene captioning and accuracy of 0.3508 for interaction detection) for both tasks on the target domain and performed on-par with single-task models in domain adaptation. Conclusion: The proposed multi-task model was able to adapt to domain shifts, incorporate novel instruments in the target domain, and perform tool-tissue interaction detection and report generation on par with single-task models.

cs.AI↗

Rethinking Surgical Instrument Segmentation: A Background Image Can Be All You Need

Data diversity and volume are crucial to the success of training deep learning models, while in the medical imaging field, the difficulty and cost of data collection and annotation are especially huge. Specifically in robotic surgery, data scarcity and imbalance have heavily affected the model accuracy and limited the design and deployment of deep learning-based surgical applications such as surgical instrument segmentation. Considering this, we rethink the surgical instrument segmentation task and propose a one-to-many data generation solution that gets rid of the complicated and expensive process of data collection and annotation from robotic surgery. In our method, we only utilize a single surgical background tissue image and a few open-source instrument images as the seed images and apply multiple augmentations and blending techniques to synthesize amounts of image variations. In addition, we also introduce the chained augmentation mixing during training to further enhance the data diversities. The proposed approach is evaluated on the real datasets of the EndoVis-2018 and EndoVis-2017 surgical scene segmentation. Our empirical analysis suggests that without the high cost of data collection and annotation, we can achieve decent surgical instrument segmentation performance. Moreover, we also observe that our method can deal with novel instrument prediction in the deployment domain. We hope our inspiring results will encourage researchers to emphasize data-centric methods to overcome demanding deep learning limitations besides data shortage, such as class imbalance, domain adaptation, and incremental learning. Our code is available at https://github.com/lofrienger/Single_SurgicalScene_For_Segmentation.

cs.CV↗

Rethinking Surgical Captioning: End-to-End Window-Based MLP Transformer Using Patches

Surgical captioning plays an important role in surgical instruction prediction and report generation. However, the majority of captioning models still rely on the heavy computational object detector or feature extractor to extract regional features. In addition, the detection model requires additional bounding box annotation which is costly and needs skilled annotators. These lead to inference delay and limit the captioning model to deploy in real-time robotic surgery. For this purpose, we design an end-to-end detector and feature extractor-free captioning model by utilizing the patch-based shifted window technique. We propose Shifted Window-Based Multi-Layer Perceptrons Transformer Captioning model (SwinMLP-TranCAP) with faster inference speed and less computation. SwinMLP-TranCAP replaces the multi-head attention module with window-based multi-head MLP. Such deployments primarily focus on image understanding tasks, but very few works investigate the caption generation task. SwinMLP-TranCAP is also extended into a video version for video captioning tasks using 3D patches and windows. Compared with previous detector-based or feature extractor-based models, our models greatly simplify the architecture design while maintaining performance on two surgical datasets. The code is publicly available at https://github.com/XuMengyaAmy/SwinMLP_TranCAP.

cs.CV↗

Class-Incremental Domain Adaptation with Smoothing and Calibration for Surgical Report Generation

Generating surgical reports aimed at surgical scene understanding in robot-assisted surgery can contribute to documenting entry tasks and post-operative analysis. Despite the impressive outcome, the deep learning model degrades the performance when applied to different domains encountering domain shifts. In addition, there are new instruments and variations in surgical tissues appeared in robotic surgery. In this work, we propose class-incremental domain adaptation (CIDA) with a multi-layer transformer-based model to tackle the new classes and domain shift in the target domain to generate surgical reports during robotic surgery. To adapt incremental classes and extract domain invariant features, a class-incremental (CI) learning method with supervised contrastive (SupCon) loss is incorporated with a feature extractor. To generate caption from the extracted feature, curriculum by one-dimensional gaussian smoothing (CBS) is integrated with a multi-layer transformer-based caption prediction model. CBS smoothes the features embedding using anti-aliasing and helps the model to learn domain invariant features. We also adopt label smoothing (LS) to calibrate prediction probability and obtain better feature representation with both feature extractor and captioning model. The proposed techniques are empirically evaluated by using the datasets of two surgical domains, such as nephrectomy operations and transoral robotic surgery. We observe that domain invariant feature learning and the well-calibrated network improves the surgical report generation performance in both source and target domain under domain shift and unseen classes in the manners of one-shot and few-shot learning. The code is publicly available at https://github.com/XuMengyaAmy/CIDACaptioning.

cs.CV↗

Learning Domain Adaptation with Model Calibration for Surgical Report Generation in Robotic Surgery

Generating a surgical report in robot-assisted surgery, in the form of natural language expression of surgical scene understanding, can play a significant role in document entry tasks, surgical training, and post-operative analysis. Despite the state-of-the-art accuracy of the deep learning algorithm, the deployment performance often drops when applied to the Target Domain (TD) data. For this purpose, we develop a multi-layer transformer-based model with the gradient reversal adversarial learning to generate a caption for the multi-domain surgical images that can describe the semantic relationship between instruments and surgical Region of Interest (ROI). In the gradient reversal adversarial learning scheme, the gradient multiplies with a negative constant and updates adversarially in backward propagation, discriminating between the source and target domains and emerging domain-invariant features. We also investigate model calibration with label smoothing technique and the effect of a well-calibrated model for the penultimate layer's feature representation and Domain Adaptation (DA). We annotate two robotic surgery datasets of MICCAI robotic scene segmentation and Transoral Robotic Surgery (TORS) with the captions of procedures and empirically show that our proposed method improves the performance in both source and target domain surgical reports generation in the manners of unsupervised, zero-shot, one-shot, and few-shot learning.

cs.RO↗