arXiv subjects

Mercy Asiedu

Publications and source records attributed to Mercy Asiedu.

6 recordsLinked to original sources

arXiv2025

MedGemma Technical Report

Artificial intelligence (AI) has significant potential in healthcare applications, but its training and deployment faces challenges due to healthcare's diverse data, complex tasks, and the need to preserve privacy. Foundation models that perform well on medical tasks and require less task-specific tuning data are critical to accelerate the development of healthcare AI applications. We introduce MedGemma, a collection of medical vision-language foundation models based on Gemma 3 4B and 27B. MedGemma demonstrates advanced medical understanding and reasoning on images and text, significantly exceeding the performance of similar-sized generative models and approaching the performance of task-specific models, while maintaining the general capabilities of the Gemma 3 base models. For out-of-distribution tasks, MedGemma achieves 2.6-10% improvement on medical multimodal question answering, 15.5-18.1% improvement on chest X-ray finding classification, and 10.8% improvement on agentic evaluations compared to the base models. Fine-tuning MedGemma further improves performance in subdomains, reducing errors in electronic health record information retrieval by 50% and reaching comparable performance to existing specialized state-of-the-art methods for pneumothorax classification and histopathology patch classification. We additionally introduce MedSigLIP, a medically-tuned vision encoder derived from SigLIP. MedSigLIP powers the visual understanding capabilities of MedGemma and as an encoder achieves comparable or better performance than specialized medical image encoders. Taken together, the MedGemma collection provides a strong foundation of medical image and text capabilities, with potential to significantly accelerate medical research and development of downstream applications. The MedGemma collection, including tutorials and model weights, can be found at https://goo.gle/medgemma.

cs.AI↗

arXiv2024

Contextual Evaluation of Large Language Models for Classifying Tropical and Infectious Diseases

While large language models (LLMs) have shown promise for medical question answering, there is limited work focused on tropical and infectious disease-specific exploration. We build on an opensource tropical and infectious diseases (TRINDs) dataset, expanding it to include demographic and semantic clinical and consumer augmentations yielding 11000+ prompts. We evaluate LLM performance on these, comparing generalist and medical LLMs, as well as LLM outcomes to human experts. We demonstrate through systematic experimentation, the benefit of contextual information such as demographics, location, gender, risk factors for optimal LLM response. Finally we develop a prototype of TRINDs-LM, a research tool that provides a playground to navigate how context impacts LLM outputs for health.

cs.CL↗

arXiv2024

A Toolbox for Surfacing Health Equity Harms and Biases in Large Language Models

Large language models (LLMs) hold promise to serve complex health information needs but also have the potential to introduce harm and exacerbate health disparities. Reliably evaluating equity-related model failures is a critical step toward developing systems that promote health equity. We present resources and methodologies for surfacing biases with potential to precipitate equity-related harms in long-form, LLM-generated answers to medical questions and conduct a large-scale empirical case study with the Med-PaLM 2 LLM. Our contributions include a multifactorial framework for human assessment of LLM-generated answers for biases, and EquityMedQA, a collection of seven datasets enriched for adversarial queries. Both our human assessment framework and dataset design process are grounded in an iterative participatory approach and review of Med-PaLM 2 answers. Through our empirical study, we find that our approach surfaces biases that may be missed via narrower evaluation approaches. Our experience underscores the importance of using diverse assessment methodologies and involving raters of varying backgrounds and expertise. While our approach is not sufficient to holistically assess whether the deployment of an AI system promotes equitable health outcomes, we hope that it can be leveraged and built upon towards a shared goal of LLMs that promote accessible and equitable healthcare.

cs.CY↗

arXiv2024

Impact of Large Language Model Assistance on Patients Reading Clinical Notes: A Mixed-Methods Study

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using LLMs to make clinical notes more readable by simplifying, extracting information from, and adding context to the notes. We piloted the tool with clinical notes donated by patients with a history of breast cancer and synthetic notes from a clinician. Participants (N=200, healthy, female-identifying patients) were randomly assigned three clinical notes in our tool with varying levels of augmentations and answered quantitative and qualitative questions evaluating their understanding of follow-up actions. Augmentations significantly increased their quantitative understanding scores. In-depth interviews were conducted with participants (N=7, patients with a history of breast cancer), revealing both positive sentiments about the augmentations and concerns about AI. We also performed a qualitative clinician-driven analysis of the model's error modes.

cs.HC↗

arXiv2023

Globalizing Fairness Attributes in Machine Learning: A Case Study on Health in Africa

With growing machine learning (ML) applications in healthcare, there have been calls for fairness in ML to understand and mitigate ethical concerns these systems may pose. Fairness has implications for global health in Africa, which already has inequitable power imbalances between the Global North and South. This paper seeks to explore fairness for global health, with Africa as a case study. We propose fairness attributes for consideration in the African context and delineate where they may come into play in different ML-enabled medical modalities. This work serves as a basis and call for action for furthering research into fairness in global health.

cs.LG↗

arXiv2021

Network-Agnostic Knowledge Transfer for Medical Image Segmentation

Conventional transfer learning leverages weights of pre-trained networks, but mandates the need for similar neural architectures. Alternatively, knowledge distillation can transfer knowledge between heterogeneous networks but often requires access to the original training data or additional generative networks. Knowledge transfer between networks can be improved by being agnostic to the choice of network architecture and reducing the dependence on original training data. We propose a knowledge transfer approach from a teacher to a student network wherein we train the student on an independent transferal dataset, whose annotations are generated by the teacher. Experiments were conducted on five state-of-the-art networks for semantic segmentation and seven datasets across three imaging modalities. We studied knowledge transfer from a single teacher, combination of knowledge transfer and fine-tuning, and knowledge transfer from multiple teachers. The student model with a single teacher achieved similar performance as the teacher; and the student model with multiple teachers achieved better performance than the teachers. The salient features of our algorithm include: 1)no need for original training data or generative networks, 2) knowledge transfer between different architectures, 3) ease of implementation for downstream tasks by using the downstream task dataset as the transferal dataset, 4) knowledge transfer of an ensemble of models, trained independently, into one student model. Extensive experiments demonstrate that the proposed algorithm is effective for knowledge transfer and easily tunable.

cs.CV↗