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Michaël Genin

Publications and source records attributed to Michaël Genin.

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A Bayesian shared-frailty spatial scan statistic model for time-to-event data

Spatial scan statistics are well known and widely used methods for the detection of spatial clusters of events. In the field of spatial analysis of time-to-event data, several models of scan statistics have been proposed. However, these models do not take into account the potential intra-unit spatial correlation of individuals nor a potential correlation between spatial units. To overcome this problem, we propose here a scan statistic based on a Cox model with shared frailty that takes into account the spatial correlation between spatial units. In simulation studies, we have shown that (i) classical models of spatial scan statistics for time-to-event data fail to maintain the type I error in the presence of intra-spatial unit correlation, and (ii) our model performs well in the presence of both intra-spatial unit correlation and inter-spatial unit correlation. Our method has been applied to epidemiological data and to the detection of spatial clusters of mortality in patients with end-stage renal disease in northern France.

stat.ME

Investigating spatial scan statistics for multivariate functional data

This paper introduces new scan statistics for multivariate functional data indexed in space. The new methods are derivated from a MANOVA test statistic for functional data, an adaptation of the Hotelling T2-test statistic, and a multivariate extension of the Wilcoxon rank-sum test statistic. In a simulation study, the latter two methods present very good performances and the adaptation of the functional MANOVA also shows good performances for a normal distribution. Our methods detect more accurate spatial clusters than an existing nonparametric functional scan statistic. Lastly we applied the methods on multivariate functional data to search for spatial clusters of abnormal daily concentrations of air pollutants in the north of France in May and June 2020.

stat.ME

Detecting spatial clusters in functional data: new scan statistic approaches

We have developed two scan statistics for detecting clusters of functional data indexed in space. The first method is based on an adaptation of a functional analysis of variance and the second one is based on a distribution-free spatial scan statistic for univariate data. In a simulation study, the distribution-free method always performed better than a nonparametric functional scan statistic, and the adaptation of the anova also performed better for data with a normal or a quasi-normal distribution. Our methods can detect smaller spatial clusters than the nonparametric method. Lastly, we used our scan statistics for functional data to search for spatial clusters of abnormal unemployment rates in France over the period 1998-2013 (divided into quarters).

stat.ME