arXiv subjects

Michael Bock

Publications and source records attributed to Michael Bock.

8 recordsLinked to original sources

arXiv2026

Optically-powered Low Power Low Noise Amplifiers for MRI

Purpose: Fully optical receive coils can potentially allow dense receiver arrays with a large channel count, reduced channel crosstalk, and less cable clutter. The power requirements of conventional low-noise amplifiers (LNAs) are prohibitive for simultaneously driving many coils through optical means, as opto-electric power conversion efficiencies can only reach about 50%. The goal is to develop low-power LNAs (LPLNA) with substantially lower power consumption without compromising noise figure (NF) and gain. Methods: A LPLNA was designed as a two-stage cascaded amplifier using an MR-compatible E-pHEMT (Enhancement-mode Pseudomorphic High Electron Mobility Transistor) transistor. The design was implemented on a single-sided printed circuit board (PCB), and its performance was compared with a commercial LNA. A four-channel shielded loop resonator array was constructed, and the signal-to-noise ratio (SNR), noise covariance, and preamplifier decoupling performance were evaluated. Results: The LPLNA had a five-fold lower electrical power consumption (40 mW) than the commercial LNA and provided comparable SNR in phantom measurements. In vivo experiments further confirmed that the LPLNA operates reliably under realistic MRI conditions. Additionally, four-channel receiver array measurements demonstrated comparable SNR within 2% of the commercial LNA and lower inter-channel noise correlation with 0.26 vs 0.3 on average. Conclusion: This study demonstrates the feasibility of LPLNAs for optically-powered RF receiver coil arrays. The LPLNA could also be applied in power-constrained or remote MRI environments.

physics.med-ph↗

arXiv2026

Optical Detuning Strategies for Shielded Loop Resonators

Purpose: To compare detuning performance and evaluate the power requirements of optical detuning methods, and to demonstrate the feasibility of an optically detuned four-channel receive array. Methods: Four optical detuning methods were compared in simulations, bench tests, and phantom measurements at 3T against conventional galvanic detuning. Passive detuning was also tested as an additional wireless detuning option. Optical power requirements for the detuning networks were investigated, and a flexible, optically detuned 4-channel shielded-loop resonator (SLR) array was constructed and tested in vivo. Results: A photodiode-PIN diode combination exhibited the highest unloaded Q (68.6) and Q ratio (1.9), with detuning performance and signal-to-noise ratio comparable to that of galvanic detuning at an optical power of 10 mW. Using this detuning strategy, in vivo images of the knee and brain were successfully acquired with a 4-channel flexible array. Conclusion: Optical detuning is a practical alternative to conventional galvanic detuning in flexible SLR arrays. With advances in optical signal and power transmission, optimizing optical detuning while meeting manageable power requirements is an important step toward fully optical receive-coil arrays. This study provides a baseline for the total optical power required for active detuning in such optical coil systems.

eess.SY↗

arXiv2026

Light Coils: MRI with Fully Optical Data and Power Transmission

In MRI, dense receiver coil arrays with a high number of coil elements are used to efficiently detect and encode the signal. Further increasing the number of coils is hampered by electrical cabling and massive electronics that introduce electromagnetic coupling, integration complexity and even safety constraints. Here we introduce the novel Light Coils concept, a fully optical MRI receive architecture in which data transmission, front-end power delivery, and coil detuning are all implemented optically, thereby reducing the massive galvanic cabling to a few optical fibers. For signal encoding, Mach-Zehnder modulators (MZM) are used to convert the MR signal from each coil onto a C-band optical carrier. The preamplifiers are driven via a power-over-fiber (PoF) system that uses a high-efficiency photovoltaic (PV) cell for optical-to-electrical power conversion. A pulse-sequence-triggered optical path controls active detuning. Jointly optimizing modulator bias, optical power and front-end gain under realistic receiver chain conditions, Light Coils can match the signal-to-noise ratio (SNR) of conventional RF coil systems with galvanic cables at MZM input powers of 5-10mW and photonic power converter inputs of 80-100mW. At a clinical 3T MRI system, we show in vivo human brain imaging with a single-channel Light Coil element with an image quality and SNR comparable to a conventional coaxial readout using the identical coil element. Extending the concept to a four-channel array using dense wavelength-division multiplexing over a single fiber, we demonstrate wavelength-selective routing with inter-channel optical isolation exceeding 28dB, reduced noise correlation compared with the galvanic reference, and parallel imaging. These results establish a scalable route towards lightweight, modular, and potentially ultra-dense MRI receive arrays based on integrated photonics and power-over-fiber.

eess.SP↗

arXiv2025

Zero Echo Time Functional MRI in Humans

Motivation: Conventional echo planar imaging(EPI) based functional MRI(fMRI) uses the BOLD contrast to map activity changes in human brains. Introducing an efficient ZTE sequence for functional brain mapping can help address limitations of EPI and demonstrate the feasibility of using T1 related changes as a surrogate marker of brain activity. Goals: To test and optimize ZTE sequence for fMRI. Methods: A ZTE sequence with radial inside out spokes was used to prepare a dynamic imaging protocol that matches conventional EPI time course. Temporal SNR and sensitivity to susceptibility differences of ZTE were evaluated and the sequence was benchmarked against BOLD EPI in a task based visual fMRI study with healthy volunteers at 3T. Results: Phantom measurements confirmed sensitivity of the ZTE protocol to the oxygen concentration. Functional activation in primary visual cortex could be detected using ZTE. Resting state networks could also be identified using independent component analysis. Discussion: ZTE-based fMRI is proposed for mapping functional activation in human brain. ZTE is robust against susceptibility artefacts and significantly reduces acoustic noise. Radial sampling pattern allows for high undersampling rates to increase temporal resolution.

physics.med-ph↗

arXiv2024

A Paradigm Shift in Catheter Development: Thermally Drawn Polymeric Fibers for MR-Guided Cardiovascular Interventions

Cardiovascular diseases (CVDs) and congenital heart diseases (CHD) pose significant global health challenges. Fluoroscopy-guided endovascular interventions, though effective, are accompanied by ionizing radiation concerns, especially in pediatric cases. Magnetic resonance imaging (MRI) emerges as a radiation-free alternative, offering superior soft tissue visualization and functional insights. However, the lack of compatible instruments remains a hurdle. We present two novel catheter systems, a tendon-driven steerable catheter and an active tracking Tiger-shaped catheter, fabricated using a unique fiber drawing technique. These catheters, showcasing mechanical properties similar to commercial counterparts, have undergone rigorous in-vitro and in-vivo testing, yielding promising outcomes. This innovative approach has the potential to streamline medical device development, thus enhancing patient care in MR-guided interventions.

physics.med-ph↗

arXiv2021

Unbiased Signal Equation for Quantitative Magnetization Transfer Mapping in Balanced Steady-State Free Precession MRI

Purpose: Quantitative magnetization transfer (qMT) imaging can be used to quantify the proportion of protons in a voxel attached to macromolecules. Here, we show that the original qMT balanced steady-state free precession (bSSFP) model is biased due to over-simplistic assumptions made in its derivation. Theory and Methods: We present an improved model for qMT bSSFP, which incorporates finite radio-frequency (RF) pulse effects as well as simultaneous exchange and relaxation. Further, a correction to finite RF pulse effects for sinc-shaped excitations is derived. The new model is compared to the original one in numerical simulations of the Bloch-McConnell equations and in previously acquired in-vivo data. Results: Our numerical simulations show that the original signal equation is significantly biased in typical brain tissue structures (by 7-20 %) whereas the new signal equation outperforms the original one with minimal bias (< 1%). It is further shown that the bias of the original model strongly affects the acquired qMT parameters in human brain structures, with differences in the clinically relevant parameter of pool-size-ratio of up to 31 %. Particularly high biases of the original signal equation are expected in an MS lesion within diseased brain tissue (due to a low T2/T1-ratio), demanding a more accurate model for clinical applications. Conclusion: The improved model for qMT bSSFP is recommended for accurate qMT parameter mapping in healthy and diseased brain tissue structures.

physics.med-ph↗

arXiv2018

Active Decoupling of Transmit and Receive Coils for Full-Duplex MRI

Objective: Concurrent excitation and acquisition in MRI is a method to acquire MRI signal from tissues with very short transverse relaxation time. Since transmit power is many orders of magnitude larger than receive signal, a weak coupling dominates the MR signal during CEA. Thus, appropriate decoupling between transmit and receive coils is required. In this study, two controllable decoupling designs are investigated for achieving isolation between coils. Methods: A modified version of isolation concept used in the full-duplex radios in communication systems is applied to acquire MRI signal using CEA. In our new method, a small copy of RF transmit signal is attenuated and delayed to generate the same coupling signal which is available in the receiver coil. Then it is subtracted from the receive signal to detect the MRI signal. The proposed decoupling method is developed and implemented in two designs: Semi-Automatic and Fully-Automatic Controllable Decoupling Designs. Results: Using Semi-Automatic Controllable Decoupling Design, decoupling of more than 75 dB is achieved. Fully-Automatic Controllable Decoupling Design provides more than 100 dB decoupling between coils which is good enough for detecting MRI signals during excitation from tissues with very short transverse relaxation time. Conclusion: This study shows feasibility of applying full duplex electronics to decouple transmit and receive coils for CEA in a clinical MRI system. Significance: These designs can automatically tune the cancellation circuit and it is a potential tool for recovering signal from tissues with very short T2 in clinical MR systems with a minor hardware modification.

physics.med-ph↗

arXiv1999

Theory of Coherent and Incoherent Nuclear Spin-Dephasing in the Heart

We present an analytical theory of susceptibility induced nuclear spin dephasing in the capillary network of myocardium. Using a strong collision approach, equations are obtained for the relaxation rate of the free induction and the spin echo decay. Simulation and experimental data are well predicted by the theory. Since paramagnetic deoxyhemoglobin as the origin of nuclear spin dephasing has a higher tissue concentration in myocardium supplied by a stenotic, i. e. significantly narrowed, coronary artery, spin dephasing might serve as a diagnostic tool. Our approach can be modified for capillary networks in other tissues than myocardium and may be applied in material science.

cond-mat.soft↗