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Mikhail Lebedev

Publications and source records attributed to Mikhail Lebedev.

5 recordsLinked to original sources

Prosthetic Hand Manipulation System Based on EMG and Eye Tracking Powered by the Neuromorphic Processor AltAi

This paper presents a novel neuromorphic control architecture for upper-limb prostheses that combines surface electromyography (sEMG) with gaze-guided computer vision. The system uses a spiking neural network deployed on the neuromorphic processor AltAi to classify EMG patterns in real time while an eye-tracking headset and scene camera identify the object within the user's focus. In our prototype, the same EMG recognition model that was originally developed for a conventional GPU is deployed as a spiking network on AltAi, achieving comparable accuracy while operating in a sub-watt power regime, which enables a lightweight, wearable implementation. For six distinct functional gestures recorded from upper-limb amputees, the system achieves robust recognition performance comparable to state-of-the-art myoelectric interfaces. When the vision pipeline restricts the decision space to three context-appropriate gestures for the currently viewed object, recognition accuracy increases to roughly 95% while excluding unsafe, object-inappropriate grasps. These results indicate that the proposed neuromorphic, context-aware controller can provide energy-efficient and reliable prosthesis control and has the potential to improve safety and usability in everyday activities for people with upper-limb amputation.

cs.RO

Neurophysiologically Realistic Environment for Comparing Adaptive Deep Brain Stimulation Algorithms in Parkinson Disease

Adaptive deep brain stimulation (aDBS) has emerged as a promising treatment for Parkinson disease (PD). In aDBS, a surgically placed electrode sends dynamically altered stimuli to the brain based on neurophysiological feedback: an invasive gadget that limits the amount of data one could collect for optimizing the control offline. As a consequence, a plethora of synthetic models of PD and those of the control algorithms have been proposed. Herein, we introduce the first neurophysiologically realistic benchmark for comparing said models. Specifically, our methodology covers not only conventional basal ganglia circuit dynamics and pathological oscillations, but also captures 15 previously dismissed physiological attributes, such as signal instabilities and noise, neural drift, electrode conductance changes and individual variability - all modeled as spatially distributed and temporally registered features via beta-band activity in the brain and a feedback. Furthermore, we purposely built our framework as a structured environment for training and evaluating deep reinforcement learning (RL) algorithms, opening new possibilities for optimizing aDBS control strategies and inviting the machine learning community to contribute to the emerging field of intelligent neurostimulation interfaces.

q-bio.NC

Communities in C.elegans connectome through the prism of non-backtracking walks

The fundamental relationship between the mesoscopic structure of neuronal circuits and organismic functions they subserve is one of the major challenges in contemporary neuroscience. Formation of structurally connected modules of neurons enacts the conversion from single-cell firing to large-scale behaviour of an organism, highlighting the importance of their accurate profiling in the data. While connectomes are typically characterized by significant sparsity of neuronal connections, recent advances in network theory and machine learning have revealed fundamental limitations of traditionally used community detection approaches in cases where the network is sparse. Here we studied the optimal community structure in the structural connectome of C.elegans, for which we exploited a non-conventional approach that is based on non-backtracking random walks, virtually eliminating the sparsity issue. In full agreement with the previous asymptotic results, we demonstrated that non-backtracking walks resolve the ground truth annotation into clusters on stochastic block models (SBM) with the size and density of the connectome better than the spectral methods related to simple random walks. Based on the cluster detectability threshold, we determined that the optimal number of modules in a recently mapped connectome of C.elegans is 10, which precisely corresponds to the number of isolated eigenvalues in the spectrum of the non-backtracking flow matrix. Broadly, our work provides a robust network-based framework to reveal mesoscopic structures in sparse connectomic datasets, paving way to further investigation of connectome mechanisms for different functions.

q-bio.NC

The formation of long-lived high-correlated states of light and polarization in high-quality semiconductor microcavity at the resonant laser excitation

The correlation function of radiation from a high-quality semiconductor microcavity at the resonant laser excitation demonstrates oscillations with surprisingly long-period and damping times of a nanosecond range. It was shown that the oscillations are not attributed to weak Rabi interaction between long-lived exciton states and intracavity electromagnetic field. The study of a response with high spectral resolution had revealed that the oscillations arise if a spectral position as well as a period of longitudinal laser modes is similar to modulation components of a microcavity transmission spectrum.

cond-mat.other

Observation of non-classical light in semiconductor microcavities

Semiconductor microcavities are widely used to study collective interactions of cavity exciton-polaritons leading to their condensation phenomenon. Exciton-light interaction is highly enhanced in such structures due to the resonance enhancement of the electromagnetic field inside the high quality cavity. Considerably lower interest is concerned to exciton states non-resonant with the cavity mode for which the exciton-photon interaction is strongly reduced due to the existence of the cavity. We point out here that these states are responsible for non-classical light generation in semiconductor microcavities.

cond-mat.mes-hall