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Min Wu

Publications and source records attributed to Min Wu.

At least 19 recordsLinked to original sources

Fluidization in Growth-Induced Morphogenesis

Elastic buckling has explained shape formation in growing tissues, yet the role of tissue fluidity remains elusive. We derive a minimal fluidized growth-elasticity model as a nonlinear analogue of Maxwell rheology. Analysis of a growing strip shows that fluidity promotes symmetry breaking under compression while regulating stress accumulation, so morphogenesis develops continuously before the elastic buckling threshold. Fluidity further controls the flow pattern, from smooth sinusoidal undulations to widened crests and localized indentations, with low fluidity favoring stronger localization.

physics.bio-ph

PAGR: Proof-Carrying Algebraic-Geometric Retrieval: A Quiver-, Provenance-, and Sheaf-Theoretic Framework for Grounded LLM Retrieval

Retrieval-augmented generation is usually formulated as a statistical information-retrieval problem. Graph-based variants add relational structure, but the mathematical status of that structure is often left underspecified. Three distinct questions tend to be conflated: which statements are certified as knowledge, which latent representations are useful for retrieval, and which multi-hop compositions are semantically admissible. We propose Proof-Carrying Algebraic-Geometric Retrieval (PAGR), a framework that separates these questions mathematically. Its symbolic layer is a many-sorted relational theory generated by a typed quiver, path equations, and positive Horn inclusions. A quiver representation assigns inner-product spaces to entity types and linear operators to relations. A cellular sheaf measures local-to-global consistency. Semiring provenance records derivations and supports machine-checkable certificates. The central principle is epistemic separation: learned geometry may rank and organize evidence, but cannot promote a hypothesis to certified ground truth. We show the certification criterion is invariant under arbitrary replacement of learned components. Further results include a conditional completeness bound, identification of the isometry group as the relevant symmetry for residual-based retrieval, a cohomological consistency diagnostic, and a bounded-bisimulation index for admissible-path expansion. PAGR is a mathematical architecture for separating where a system should look from what it is allowed to treat as knowledge.

math.RT

IBLTs Measure Before They Decode: Self-Sizing Set Reconciliation for Database Consistency Verification

Cross-system data replication pipelines cannot confirm end-to-end consistency from the local guarantees of each hop, so the two endpoints must be compared directly on a periodic basis. Once the rows of a fixed snapshot are normalized into fingerprints, the task reduces to finding the symmetric difference of the two sets. Set reconciliation encodes both sets with an Invertible Bloom Lookup Table (IBLT), whose communication grows only with the difference cardinality $d$ and is independent of table size, which suits large tables. The capacity of an IBLT, however, must be fixed while $d$ is still unknown. Across 41,603 production reconciliations over 90 days, nonzero $d$ spans about seven orders of magnitude, and no reliable empirical constant exists. We show that the count array of an IBLT has already measured $d$ before decoding. The measurement is in-band: it is carried by the recovery sketch itself and adds no bytes dedicated to estimation. A mapping-aware theorem carries the same construction to Irregular, Rateless, and MET IBLTs. The protocol reads the estimate only after a decoding failure; we prove that the failure-conditioned lower quantile bounds the risk of underestimation, which gives the second-round capacity a configurable success-probability guarantee. On this basis we build a self-sizing protocol: the first round attempts recovery with a small sketch and stops there on success; on failure it reads $d$ and sets the second-round capacity, completing reconciliation in at most two rounds. Against a controlled oracle, communication is 1.29--1.47 times that of a scheme given $d$ in advance; production workload characterization, relational-database replay, and a cross-city KV deployment confirm the end-to-end mechanism. Measurement and recovery share one IBLT and need no separate estimation structure.

cs.DB

ComBodied Agents: a New Paradigm of Human-Centric Agentic AI

After an older adult misses a medication dose, a software agent can send another reminder and an embodied agent can bring the medication. Yet neither explains whether the person forgot, is confused, has side effects, or deliberately refused, nor what support is appropriate. This reveals a structural gap in Agentic AI: Digital Agents primarily transform software states, while Embodied Agents transform physical states; neither makes a person's evolving state and agency the primary object of modeling, intervention, and evaluation. We introduce Combodied Agents, a human-centered paradigm that perceives, models, predicts, and supports individual human-state trajectories over time, using software tools, sensors, wearables, robots, and human services as action channels rather than end goals. We unify fragmented capabilities across personal assistants, health agents, AI companions, and adaptive human--AI systems into a closed loop: event-based multimodal perception reconstructs meaningful personal events; longitudinal, correctable memory provides temporal context; Personal World Models estimate future personal states and outcomes under alternative decisions and interventions; and an admissible intervention policy selects proportionate support under consent, uncertainty, safety, reversibility, and user control. Feedback from the person and environment updates the loop. Rather than requiring an exhaustive Human Digital Twin, the framework uses purpose-bounded, uncertainty-aware, user-correctable representations. We organize the design space by human-state targets, relational contexts, and agent roles, and propose scenario-centered evaluation, agency-preservation metrics, benchmark requirements, edge-native personal models, and governance directions. Combodied Agents shift Agentic AI from external task completion toward sustained human benefit.

cs.AI

Multi-Source Dynamic Graph Learning for Compound-Flood Forecasting in Managed Coastal Systems

Compound flooding in managed coastal systems is influenced by hydrological conditions and water-management activity observed across multiple monitoring stations. Current forecasting models can capture temporal dependencies with low average errors, but global error metrics may conceal poor reproduction of prolonged high-water plateaus that are relevant to flood early warning. Because hydrometeorological and operational signals are distributed across heterogeneous gages, single-site records do not fully represent high-water dynamics. Nevertheless, unconstrained fusion of cross-site signals can degrade the stability of local temporal forecasts. This work proposes an anchored forecasting framework that incorporates cross-site information through state- and lead-dependent bounded residual corrections. A multi-source regime representation constructed from hydrometeorological and operational observations adaptively calibrates inter-site relationships and correction scales, enabling targeted cross-site adjustment while preserving the local temporal forecast as a stable anchor. Beyond conventional global error statistics, we evaluate event-scale high-water characteristics through the temporal alignment of forecasted and observed high-water processes. Experiments demonstrate that selectively integrating multi-station dynamic conditions improves the prediction reliability of sustained high-water plateaus while maintaining high accuracy during routine hydrological conditions, supporting flood early warning and water-management decision support.

cs.LG

Continuum modeling of fluidic and elastic flow during growth-driven wound closure in partial-EMT cell monolayers

Large-scale circular gap closure occurs over a time scale on which cell growth and proliferation become important. Growth is the main driver of the closing process, while cell dynamics such as elongation and intercalation reflect elastic and fluidic contributions to tissue deformation. We develop a novel fluidized growth-elasticity framework as a nonlinear analogue of a Maxwell fluid with growth. The framework decomposes the experimentally observable strain rate into the additive sum of the growth, elastic, and fluidic strain rates, thus enabling the separate quantification of these contributions from tissue kinematics and allowing the roles of tissue elasticity and fluidity (the inverse of viscosity) to be characterized. We apply the model to large circular gaps ($\sim$1.7 mm in diameter) in confluent monolayers of mouse embryonic epicardial cells (MEC1) under two conditions, without and with TGF-$\beta$ treatment. We show that both tissue fluidity and the elastic properties associated with fiber reinforcement are critical for reproducing the closure kinematics. Specifically, we predict that the treated condition has lower fluidity, associated with a lower fluidic deformation rate and a higher elastic deformation rate than the untreated condition, in agreement with the experimental observations.

physics.flu-dyn

Biologically Informed Deep Neural Networks for Multi-Omic Integration, Pathway Activity Inference and Risk Stratification in Cancer

Integrating complex, multi-omics data presents significant challenges. Existing approaches often face a trade-off between model interpretability and representational capacity, with most either relying on post-hoc interpretation or use linear models that may overlook complex interactions. We report Pathway Activity Autoencoders for the multi-omics setting, which embed prior knowledge via pathway-informed architectural constraints, fostering interpretability, while preserving representational power. Our multi-omic framework is applied in the context of breast cancer and is evaluated in survival prediction and subtype classification with results indicating a positive effect of integration. We conduct analysis of individual omics layer impact on end-task performance, revealing that gene, protein, and microRNA expression layers provide the strongest contribution. Repeatability studies indicate that, while dropout improves model robustness and consistency, excessive regularisation can reduce predictive performance. Finally, visualizations of the learned feature space illustrate the framework's intrinsic transparency and clinical relevance. The results underscore the value of multi-omic integration and delineate the impact of individual omics layers, establishing practical guidelines for integration within our framework. Overall, our pathway activity autoencoder frameworks yield superior latent representations that are biologically meaningful and are directly translatable into clinically relevant insights.

cs.LG

A phase-field model for viscoelastic compressible tumor growth

It is well known that growing tumors generate and respond to stress in their local microenvironment. Tissue re-arrangements can relax these mechanical stresses and make the tissue more fluid-like. Further, intricate coupling between mechanotransduction and biochemical signaling leads to complex patterns of growth. To predict the outcomes of these nonlinear interactions, we develop a phase-field model to simulate tumors growing into a surrounding medium taking into account their elastic and viscous properties as well as their compressibilities. We couple continuum modeling of the viscoelastic mechanics to the concentration of a diffusible growth-promoting nutrient in a mass conservative way. The phase-field method is a stable and flexible way to describe the dynamics of arbitrarily shaped tumors. We demonstrate convergence of the phase-field model to a sharp interface model in radially symmetric geometries and can observe progression to stationary tumors. However, our results show that these stationary symmetric tumors are subject to symmetry-breaking instabilities in 2D and 3D driven by two primary mechanisms: (i) elastic buckling instabiliies due to differential growth induced by the nutrient gradient and (ii) instabilities generated by apoptosis-related volumetric loss. Further, tissue fluidity and compressibility can lead to changes in tumor topologies. Our modeling framework provides a robust methodology for investigating how tissue mechanics and growth factor signaling influence the progression and invasive potential of solid tumors.

cond-mat.soft

Connectivity Estimation using Stochastic Graph Heat Modelling

A growing number of techniques leverage the spatial structures that underlie many real-world datasets. Despite these advances, the complementary task of estimating spatial structures and understanding their role within these techniques has often been overlooked. In neurophysiological data analysis specifically, numerous methods exist to estimate brain connectivity, but most are not explicitly model-based, dynamic, multivariate, or directed. To address these limitations, we previously introduced noise-driven heat modelling on graphs for neurophysiological connectivity estimation. In this study, we extend this framework by relaxing earlier noise assumptions and adding regularisation to improve robustness. We also develop a simulation procedure to characterise and evaluate our technique in a controlled setting. Finally, we demonstrate that the technique is able to capture meaningful spatial structure across two experiments, each using two real-world datasets. The explicit model formulation of our connectivity estimator has the potential to improve the interpretability of graph-based techniques across a wide range of applications. The code implementing our method is available at https://github.com/sgoerttler/Heat_Connectivity.

stat.ML

Minimizing the Hidden Cost of Scales: Graph-Guided Ultra-Low-Bit Quantization for Large Language Models

Post-training quantization (PTQ) is critical for the efficient deployment of large language models (LLMs). Recent ultra-low-bit PTQ methods rely on rigid weight-saliency assumptions or position heuristics, introducing substantial hidden scaling overhead. We propose SAGE-PTQ (Saliency-Aware Graph-guided Efficient PTQ), a novel ultra-low-bit quantization framework for LLMs that minimizes hidden scaling cost. SAGE-PTQ separates salient and unsalient weights using distributional statistics, then models subsampled unsalient weights as a sparse graph to estimate the optimal number of groups per layer. SAGE-PTQ applies dual-mode quantization, assigning multi-bit precision to salient weights and binarizing unsalient weights. To reduce scaling overhead, SAGE-PTQ uses one per-channel scale for salient weights and one scalar per unsalient group. Finally, SAGE-PTQ implements adaptive saliency thresholding to select the optimal saliency ratio per matrix. SAGE-PTQ achieves 1.03 weight bits and only 0.004 scaling bits per matrix on average, outperforming state-of-the-art methods such as BiLLM and PB-LLM. On LLaMA-3-8B, SAGE-PTQ achieves 6.74 WikiText2 perplexity, compared to 55.8 for BiLLM, while using less than 50% of BiLLM's GPU memory. On LLaMA-2-70B, SAGE-PTQ provides 1.5x faster decoding on one NVIDIA L40 GPU, demonstrating practical inference efficiency.

cs.AI

Revisiting ML Training under Fully Homomorphic Encryption: Convergence Guarantees, Differential Privacy, and Efficient Algorithms

We present the first theoretical convergence analysis of machine learning training under fully homomorphic encryption (FHE), combined with a differentially private (DP) training algorithm tailored to encrypted computation. Our approach improves computational efficiency over standard differentially private gradient descent (DP-GD) while achieving comparable utility. In particular, we prove convergence of approximate gradient descent using polynomial approximations of activation and loss functions, which are required for FHE compatibility. To preserve privacy in downstream tasks, we integrate differential privacy without relying on costly per-sample gradient clipping, enabling scalable encrypted learning. We also provide data-independent hyperparameter selection and theoretically grounded strategies for polynomial approximation which can be of independent interest. Together, these contributions advance the feasibility of efficient, private, and secure machine learning on sensitive data.

cs.LG

PrismFlow: Residual Dynamics for Flow Matching in Time-Series Generation

Generating high-quality time-series data is challenging because real-world signals often exhibit multimodal patterns and multiscale dynamics, including oscillations and high-frequency variations. Flow Matching (FM) offers an efficient alternative to diffusion models, but practical implementations typically rely on a single finite-capacity global vector-field estimator. In such heterogeneous temporal distributions, distinct regimes may pass through nearby flow states while requiring incompatible conditional velocities. A monolithic estimator trained with the standard $\ell_2$ velocity-matching objective may therefore learn an overly smoothed approximation of the local transport field. This estimator-level smoothing can attenuate branch-specific dynamics, leading to spectral distortion and poor mode coverage. To address this, we propose PrismFlow, a new FM method with Koopman-inspired dynamical experts. Each expert learns residual corrections in a latent space where local nonlinear temporal evolution can be approximated by linear transitions. We further propose a confidence-aware Winner-Take-All (WTA) objective that updates only the expert best aligned with each sample while masking gradients to the others, encouraging mode-specific specialization. During sampling, the selected expert adds a residual dynamical correction to the global transport field, preserving FM stability while recovering fine-grained and high-frequency temporal structures. Across various benchmarks, PrismFlow effectively mitigates the spectral contraction in standard FM and achieves state-of-the-art performance, with a 15.6% gain in Context-FID and a 38.6% improvement in Discriminative Score, while remaining robust in low-data settings and effective for forecasting and imputation.

cs.LG

GESR: A Genetic Programming-Based Symbolic Regression Method with Gene Editing

Mathematical formulas serve as a language through which humans communicate with nature. Discovering mathematical laws from scientific data to describe natural phenomena has been a long-standing pursuit of humanity for centuries. In the field of artificial intelligence, this challenge is known as the symbolic regression problem. Among existing symbolic regression approaches, Genetic Programming (GP) based on evolutionary algorithms remains one of the most classical and widely adopted methods. GP simulates the evolutionary process across generations through genetic mutation and crossover. However, mutations and crossovers in GP are entirely random. While this randomness effectively mimics natural evolution, it inevitably produces both beneficial and detrimental variations. If there existed a metaphorical `God` capable of foreseeing which genetic mutations or crossovers would yield superior outcomes and performing targeted gene editing accordingly, the efficiency of evolution could be substantially improved. Motivated by this idea, we propose in this paper a symbolic regression approach based on gene editing, termed GESR. In GESR, we trained two "hands of God" (two BERT models). Among them, the first leverages the BERT's masked language modeling capability to guide the mutation of genes (expression symbols). The other BERT model guides the crossover of individual genes by predicting the crossover point. Experimental results demonstrate that GESR significantly improves computational efficiency compared with traditional GP algorithms and achieves strong overall performance across multiple symbolic regression tasks.

cs.AI

SDFlow: Similarity-Driven Flow Matching for Time Series Generation

Vector quantization (VQ) with autoregressive (AR) token modeling is a widely adopted and highly competitive paradigm for time-series generation. However, such models are fundamentally limited by exposure bias: during inference, errors can accumulate across sequential predictions, leading to pronounced quality degradation in long-horizon generation. To address this, we propose SDFlow ($\textbf{S}$imilarity-$\textbf{D}$riven $\textbf{Flow}$ Matching), a non-autoregressive framework that operates entirely in the frozen VQ latent space and enables parallel sequence generation via flow matching. We tackle three key challenges in making this transition: (1) eliminating exposure bias by replacing step-wise token prediction with a global transport map; (2) mitigating the high-dimensionality of VQ token spaces via a low-rank manifold decomposition with a learned anchor prior over the latent manifold; and (3) incorporating discrete supervision into continuous transport dynamics by introducing a categorical posterior over codebook indices within a variational flow-matching formulation. Extensive experiments show that SDFlow achieves state-of-the-art performance, improving Discriminative Score and substantially reducing Context-FID, particularly for challenging long-sequence generation. Moreover, SDFlow provides significant inference speedups over autoregressive baselines, offering both high fidelity and computational efficiency. Code is available at https://anonymous.4open.science/r/SDFlow-D6F3/

cs.AI

CERSA: Cumulative Energy-Retaining Subspace Adaptation for Memory-Efficient Fine-Tuning

To mitigate the memory constraints associated with fine-tuning large pre-trained models, existing parameter-efficient fine-tuning (PEFT) methods, such as LoRA, rely on low-rank updates. However, such updates fail to fully capture the rank characteristics of the weight modifications observed in full-parameter fine-tuning, resulting in a performance gap. Furthermore, LoRA and other existing PEFT methods still require substantial memory to store the full set of frozen weights, limiting their efficiency in resource-constrained settings. To addres these limitations, we introduce Cumulative Energy-Retaining Subspace Adaptation (CERSA), a novel fine-tuning paradigm that leverages singular value decomposition (SVD) to retain only the principal components responsible for 90% to 95% of the spectral energy. By fine-tuning low-rank representations derived from this principal subspace, CERSA significantly reduces memory consumption. We conduct extensive evaluations of CERSA across models of varying scales and domains, including image recognition, text-to-image generation, and natural language understanding. Empirical results demonstrate that CERSA consistently outperforms state-of-the-art PEFT methods while achieving substantially lower memory requirements. The code will be publicly released.

cs.LG

Compress Then Adapt? No, Do It Together via Task-aware Union of Subspaces

Adapting large pretrained models to diverse tasks is now routine, yet the two dominant strategies of parameter-efficient fine-tuning (PEFT) and low-rank compression are typically composed in sequence. This decoupled practice first compresses and then fine-tunes adapters, potentially misaligning the compressed subspace with downstream objectives and squandering a global parameter budget. To overcome this limitation, we introduce JACTUS (Joint Adaptation and Compression with a Task-aware Union of Subspaces), a single framework that unifies compression and adaptation. From a small calibration set, JACTUS estimates input and pre-activation gradient covariances, forms their orthogonal union with the pretrained weight subspace, performs a projected low-rank approximation inside this union, allocates rank globally by marginal gain per parameter, and trains only a compact core matrix. This explicitly mitigates the potential misalignment between the compressed subspace and downstream objectives by coupling the directions preserved for compression with those required for adaptation, yielding a deployable low-rank model that avoids retaining full frozen weights while enabling fast and robust tuning. On vision, JACTUS attains an average 89.2% accuracy on ViT-Base across eight datasets at 80% retained parameters, surpassing strong 100% PEFT baselines (e.g., DoRA 87.9%). On language, JACTUS achieves an 80.9% average on Llama2-7B commonsense QA at the same 80% retained-parameter budget, outperforming 100% PEFT (e.g., DoRA 79.7%) and exceeding prior compress-then-finetune pipelines under the same ratained-parameter budget. We will release code.

cs.AI

Understanding Semantic Perturbations on In-Processing Generative Image Watermarks

The widespread deployment of high-fidelity generative models has intensified the need for reliable mechanisms for provenance and content authentication. In-processing watermarking, embedding a signature into the generative model's synthesis procedure, has been advocated as a solution and is often reported to be robust to standard post-processing (such as geometric transforms and filtering). Yet robustness to semantic manipulations that alter high-level scene content while maintaining reasonable visual quality is not well studied or understood. We introduce a simple, multi-stage framework for systematically stress-testing in-processing generative watermarks under semantic drift. The framework utilizes off-the-shelf models for object detection, mask generation, and semantically guided inpainting or regeneration to produce controlled, meaning-altering edits with minimal perceptual degradation. Based on extensive experiments on representative schemes, we find that robustness varies significantly with the degree of semantic entanglement: methods by which watermarks remain detectable under a broad suite of conventional perturbations can fail under semantic edits, with watermark detectability in many cases dropping to near zero while image quality remains high. Overall, our results reveal a critical gap in current watermarking evaluations and suggest that watermark designs and benchmarking must explicitly account for robustness against semantic manipulation.

cs.CV

Observation of a Reconstructed Chern Insulator in Twisted Bilayer MoTe2

Twisted bilayer MoTe2 is a prototypical moire material in which long-wavelength superlattices amplify electron correlations, enabling a wealth of emergent quantum phases. To date, experimental efforts have focused primarily on small twist angles (typically smaller than 4deg ), whereas the larger-angle regime-where moire bands become more dispersive and correlations are reduced-has remained largely unexplored. Here we chart the topological phase space of tMoTe2 at a relatively large twist angle of approximately 4.54deg, accessing a moderately correlated regime with enhanced bandwidth. In contrast to small-angle devices that predominantly host fractional quantum anomalous Hall or spin Hall responses, we uncover multiple Chern-insulating states with C = 1 at moire fillings v = -1, -0.53 and -1/2. Strikingly, at v = -2/3 a magnetic field induces a fractional Chern insulator accompanied by an insulator-metal transition. Our results broaden the topological phase diagram of tMoTe2 and establish large-angle moire superlattices as a versatile platform for engineering robust topological states beyond the strong-correlation limit.

cond-mat.mes-hall