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Min Xu

Publications and source records attributed to Min Xu.

At least 217 records · Page 12Linked to original sources

Weight Encode Reconstruction Network for Computed Tomography in a Semi-Case-Wise and Learning-Based Way

Classic algebraic reconstruction technology (ART) for computed tomography requires pre-determined weights of the voxels for projecting pixel values. However, such weight cannot be accurately obtained due to the limitation of the physical understanding and computation resources. In this study, we propose a semi-case-wise learning-based method named Weight Encode Reconstruction Network (WERNet) to tackle the issues mentioned above. The model is trained in a self-supervised manner without the label of a voxel set. It contains two branches, including the voxel weight encoder and the voxel attention part. Using gradient normalization, we are able to co-train the encoder and voxel set numerically stably. With WERNet, the reconstructed result was obtained with a cosine similarity greater than 0.999 with the ground truth. Moreover, the model shows the extraordinary capability of denoising comparing to the classic ART method. In the generalization test of the model, the encoder is transferable from a voxel set with complex structure to the unseen cases without the deduction of the accuracy.

eess.IV↗

Experimental Analysis of Legendre Decomposition in Machine Learning

In this technical report, we analyze Legendre decomposition for non-negative tensor in theory and application. In theory, the properties of dual parameters and dually flat manifold in Legendre decomposition are reviewed, and the process of tensor projection and parameter updating is analyzed. In application, a series of verification experiments and clustering experiments with parameters on submanifold were carried out, hoping to find an effective lower dimensional representation of the input tensor. The experimental results show that the parameters on submanifold have no ability to be directly used as low-rank representations. Combined with analysis, we connect Legendre decomposition with neural networks and low-rank representation applications, and put forward some promising prospects.

cs.LG↗

Improving Utility and Security of the Shuffler-based Differential Privacy

When collecting information, local differential privacy (LDP) alleviates privacy concerns of users because their private information is randomized before being sent it to the central aggregator. LDP imposes large amount of noise as each user executes the randomization independently. To address this issue, recent work introduced an intermediate server with the assumption that this intermediate server does not collude with the aggregator. Under this assumption, less noise can be added to achieve the same privacy guarantee as LDP, thus improving utility for the data collection task. This paper investigates this multiple-party setting of LDP. We analyze the system model and identify potential adversaries. We then make two improvements: a new algorithm that achieves a better privacy-utility tradeoff; and a novel protocol that provides better protection against various attacks. Finally, we perform experiments to compare different methods and demonstrate the benefits of using our proposed method.

cs.CR↗

Few shot domain adaptation for in situ macromolecule structural classification in cryo-electron tomograms

Motivation: Cryo-Electron Tomography (cryo-ET) visualizes structure and spatial organization of macromolecules and their interactions with other subcellular components inside single cells in the close-to-native state at sub-molecular resolution. Such information is critical for the accurate understanding of cellular processes. However, subtomogram classification remains one of the major challenges for the systematic recognition and recovery of the macromolecule structures in cryo-ET because of imaging limits and data quantity. Recently, deep learning has significantly improved the throughput and accuracy of large-scale subtomogram classification. However often it is difficult to get enough high-quality annotated subtomogram data for supervised training due to the enormous expense of labeling. To tackle this problem, it is beneficial to utilize another already annotated dataset to assist the training process. However, due to the discrepancy of image intensity distribution between source domain and target domain, the model trained on subtomograms in source domainmay perform poorly in predicting subtomogram classes in the target domain. Results: In this paper, we adapt a few shot domain adaptation method for deep learning based cross-domain subtomogram classification. The essential idea of our method consists of two parts: 1) take full advantage of the distribution of plentiful unlabeled target domain data, and 2) exploit the correlation between the whole source domain dataset and few labeled target domain data. Experiments conducted on simulated and real datasets show that our method achieves significant improvement on cross domain subtomogram classification compared with baseline methods.

q-bio.QM↗

Improving Lesion Segmentation for Diabetic Retinopathy using Adversarial Learning

Diabetic Retinopathy (DR) is a leading cause of blindness in working age adults. DR lesions can be challenging to identify in fundus images, and automatic DR detection systems can offer strong clinical value. Of the publicly available labeled datasets for DR, the Indian Diabetic Retinopathy Image Dataset (IDRiD) presents retinal fundus images with pixel-level annotations of four distinct lesions: microaneurysms, hemorrhages, soft exudates and hard exudates. We utilize the HEDNet edge detector to solve a semantic segmentation task on this dataset, and then propose an end-to-end system for pixel-level segmentation of DR lesions by incorporating HEDNet into a Conditional Generative Adversarial Network (cGAN). We design a loss function that adds adversarial loss to segmentation loss. Our experiments show that the addition of the adversarial loss improves the lesion segmentation performance over the baseline.

eess.IV↗

A Deep Learning System That Generates Quantitative CT Reports for Diagnosing Pulmonary Tuberculosis

We developed a deep learning model-based system to automatically generate a quantitative Computed Tomography (CT) diagnostic report for Pulmonary Tuberculosis (PTB) cases.501 CT imaging datasets from 223 patients with active PTB were collected, and another 501 cases from a healthy population served as negative samples.2884 lesions of PTB were carefully labeled and classified manually by professional radiologists.Three state-of-the-art 3D convolution neural network (CNN) models were trained and evaluated in the inspection of PTB CT images. Transfer learning method was also utilized during this process. The best model was selected to annotate the spatial location of lesions and classify them into miliary, infiltrative, caseous, tuberculoma and cavitary types simultaneously.Then the Noisy-Or Bayesian function was used to generate an overall infection probability.Finally, a quantitative diagnostic report was exported.The results showed that the recall and precision rates, from the perspective of a single lesion region of PTB, were 85.9% and 89.2% respectively. The overall recall and precision rates,from the perspective of one PTB case, were 98.7% and 93.7%, respectively. Moreover, the precision rate of the PTB lesion type classification was 90.9%.The new method might serve as an effective reference for decision making by clinical doctors.

eess.IV↗

Visual Analytics of Student Learning Behaviors on K-12 Mathematics E-learning Platforms

With increasing popularity in online learning, a surge of E-learning platforms have emerged to facilitate education opportunities for k-12 (from kindergarten to 12th grade) students and with this, a wealth of information on their learning logs are getting recorded. However, it remains unclear how to make use of these detailed learning behavior data to improve the design of learning materials and gain deeper insight into students' thinking and learning styles. In this work, we propose a visual analytics system to analyze student learning behaviors on a K-12 mathematics E-learning platform. It supports both correlation analysis between different attributes and a detailed visualization of user mouse-movement logs. Our case studies on a real dataset show that our system can better guide the design of learning resources (e.g., math questions) and facilitate quick interpretation of students' problem-solving and learning styles.

cs.HC↗

Structured Modeling of Joint Deep Feature and Prediction Refinement for Salient Object Detection

Recent saliency models extensively explore to incorporate multi-scale contextual information from Convolutional Neural Networks (CNNs). Besides direct fusion strategies, many approaches introduce message-passing to enhance CNN features or predictions. However, the messages are mainly transmitted in two ways, by feature-to-feature passing, and by prediction-to-prediction passing. In this paper, we add message-passing between features and predictions and propose a deep unified CRF saliency model . We design a novel cascade CRFs architecture with CNN to jointly refine deep features and predictions at each scale and progressively compute a final refined saliency map. We formulate the CRF graphical model that involves message-passing of feature-feature, feature-prediction, and prediction-prediction, from the coarse scale to the finer scale, to update the features and the corresponding predictions. Also, we formulate the mean-field updates for joint end-to-end model training with CNN through back propagation. The proposed deep unified CRF saliency model is evaluated over six datasets and shows highly competitive performance among the state of the arts.

cs.CV↗

Deep Learning-Based Strategy for Macromolecules Classification with Imbalanced Data from Cellular Electron Cryotomography

Deep learning model trained by imbalanced data may not work satisfactorily since it could be determined by major classes and thus may ignore the classes with small amount of data. In this paper, we apply deep learning based imbalanced data classification for the first time to cellular macromolecular complexes captured by Cryo-electron tomography (Cryo-ET). We adopt a range of strategies to cope with imbalanced data, including data sampling, bagging, boosting, Genetic Programming based method and. Particularly, inspired from Inception 3D network, we propose a multi-path CNN model combining focal loss and mixup on the Cryo-ET dataset to expand the dataset, where each path had its best performance corresponding to each type of data and let the network learn the combinations of the paths to improve the classification performance. In addition, extensive experiments have been conducted to show our proposed method is flexible enough to cope with different number of classes by adjusting the number of paths in our multi-path model. To our knowledge, this work is the first application of deep learning methods of dealing with imbalanced data to the internal tissue classification of cell macromolecular complexes, which opened up a new path for cell classification in the field of computational biology.

eess.IV↗

Learn to segment single cells with deep distance estimator and deep cell detector

Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations of image setting may lead to poor segmentation results. Recent development of deep convolutional neural networks(CNN) provides a potentially efficient, general and robust method for segmentation. Most existing CNN-based methods treat segmentation as a pixel-wise classification problem. However, three unique problems of cell images adversely affect segmentation accuracy: lack of established training dataset, few pixels on cell boundaries, and ubiquitous blurry features. The problem becomes especially severe with densely packed cells, where a pixel-wise classification method tends to identify two neighboring cells with blurry shared boundary as one cell, leading to poor cell count accuracy and affecting subsequent analysis. Here we developed a different learning strategy that combines strengths of CNN and watershed algorithm. The method first trains a CNN to learn Euclidean distance transform of binary masks corresponding to the input images. Then another CNN is trained to detect individual cells in the Euclidean distance transform. In the third step, the watershed algorithm takes the outputs from the previous steps as inputs and performs the segmentation. We tested the combined method and various forms of the pixel-wise classification algorithm on segmenting fluorescence and transmitted light images. The new method achieves similar pixel accuracy but significant higher cell count accuracy than pixel-wise classification methods do, and the advantage is most obvious when applying on noisy images of densely packed cells.

q-bio.QM↗

The $h$-edge tolerable diagnosability of balanced hypercubes

To measure the fault diagnosis capability of a multiprocessor system with faulty links, Zhu et al. [Theoret. Comput. Sci. 758 (2019) 1--8] introduced the $h$-edge tolerable diagnosability. This kind of diagnosability is a generalization of the concept of traditional diagnosability. In this paper, as complement to the results in [Theoret. Comput. Sci. 760 (2019) 1--14], we completely determine the $h$-edge tolerable diagnosability of balanced hypercubes $BH_n$ under the PMC model and the MM$^*$ model. Thus, the traditional diagnosability of $BH_n$ is also determined.

math.CO↗

High-dimensional nonparametric density estimation via symmetry and shape constraints

We tackle the problem of high-dimensional nonparametric density estimation by taking the class of log-concave densities on $\mathbb{R}^p$ and incorporating within it symmetry assumptions, which facilitate scalable estimation algorithms and can mitigate the curse of dimensionality. Our main symmetry assumption is that the super-level sets of the density are $K$-homothetic (i.e. scalar multiples of a convex body $K \subseteq \mathbb{R}^p$). When $K$ is known, we prove that the $K$-homothetic log-concave maximum likelihood estimator based on $n$ independent observations from such a density has a worst-case risk bound with respect to, e.g., squared Hellinger loss, of $O(n^{-4/5})$, independent of $p$. Moreover, we show that the estimator is adaptive in the sense that if the data generating density admits a special form, then a nearly parametric rate may be attained. We also provide worst-case and adaptive risk bounds in cases where $K$ is only known up to a positive definite transformation, and where it is completely unknown and must be estimated nonparametrically. Our estimation algorithms are fast even when $n$ and $p$ are on the order of hundreds of thousands, and we illustrate the strong finite-sample performance of our methods on simulated data.

math.ST↗

Studies of Reynolds Stress and the Turbulent Generation of Edge Poloidal Flows on the HL-@A Tokamak

Several new results in the physics of edge poloidal flows, turbulent stresses and momentum transport are reported. These are based on experiments on the HL-2A tokamak. Significant deviation from neoclassical prediction for mean poloidal flow in Ohmic and L mode discharges is deduced from direct measurements of the turbulent Reynolds stress. The deviation increases with heating power. The turbulent poloidal viscosity is synthesized from fluctuation data, and is found to be comparable to the turbulent particle diffusivity. The intrinsic poloidal torque is deduced from synthesis, for the first time. PDFs of particle flux and Reynolds stress are obtained. Both exhibit fat tails and large kurtosis, suggesting that the momentum transport process represented by the Reynolds stress is not well described by quasilinear calculations.

physics.plasm-ph↗

Optimal Rates for Community Estimation in the Weighted Stochastic Block Model

Community identification in a network is an important problem in fields such as social science, neuroscience, and genetics. Over the past decade, stochastic block models (SBMs) have emerged as a popular statistical framework for this problem. However, SBMs have an important limitation in that they are suited only for networks with unweighted edges; in various scientific applications, disregarding the edge weights may result in a loss of valuable information. We study a weighted generalization of the SBM, in which observations are collected in the form of a weighted adjacency matrix and the weight of each edge is generated independently from an unknown probability density determined by the community membership of its endpoints. We characterize the optimal rate of misclustering error of the weighted SBM in terms of the Renyi divergence of order 1/2 between the weight distributions of within-community and between-community edges, substantially generalizing existing results for unweighted SBMs. Furthermore, we present a computationally tractable algorithm based on discretization that achieves the optimal error rate. Our method is adaptive in the sense that the algorithm, without assuming knowledge of the weight densities, performs as well as the best algorithm that knows the weight densities.

math.ST↗

Learning Multi-level Deep Representations for Image Emotion Classification

In this paper, we propose a new deep network that learns multi-level deep representations for image emotion classification (MldrNet). Image emotion can be recognized through image semantics, image aesthetics and low-level visual features from both global and local views. Existing image emotion classification works using hand-crafted features or deep features mainly focus on either low-level visual features or semantic-level image representations without taking all factors into consideration. The proposed MldrNet combines deep representations of different levels, i.e. image semantics, image aesthetics, and low-level visual features to effectively classify the emotion types of different kinds of images, such as abstract paintings and web images. Extensive experiments on both Internet images and abstract paintings demonstrate the proposed method outperforms the state-of-the-art methods using deep features or hand-crafted features. The proposed approach also outperforms the state-of-the-art methods with at least 6% performance improvement in terms of overall classification accuracy.

cs.CV↗

Adjoint-based optimization for thrust performance of a three-dimensional pitching-rolling plate

An adjoint-based optimization is applied to study the thrust performance of a pitching-rolling ellipsoidal plate in a uniform stream at Reynolds number 100. To achieve the highest thrust, the optimal kinematics of pitching-rolling motion is sought in a large control space including the pitching amplitude, the rolling amplitude, and the phase delay between the pitching and rolling motion. A continuous adjoint approach with boundary motion being handled by non-cylindrical calculous is developed as a computationally efficient optimization algorithm to deal with the large control space with morphing domain. The comparison between the optimal motion and other reference motions shows a significant improvement of thrust from the increase of rolling amplitude and an optimal phase delay of $122.6^\circ$ between the pitching and the rolling motion. The combination of these two factors impacts the overall thrust performance through their strong effects on the angle of attack, circulation, and the pressure distribution on the plate. Further wake structure analysis suggests that the optimal control improves its propulsive performance by generating a stronger leading-edge vortex (LEV) and straightening the wake deflection.

physics.flu-dyn↗

Dual Pattern Learning Networks by Empirical Dual Prediction Risk Minimization

Motivated by the observation that humans can learn patterns from two given images at one time, we propose a dual pattern learning network architecture in this paper. Unlike conventional networks, the proposed architecture has two input branches and two loss functions. Instead of minimizing the empirical risk of a given dataset, dual pattern learning networks is trained by minimizing the empirical dual prediction loss. We show that this can improve the performance for single image classification. This architecture forces the network to learn discriminative class-specific features by analyzing and comparing two input images. In addition, the dual input structure allows the network to have a considerably large number of image pairs, which can help address the overfitting issue due to limited training data. Moreover, we propose to associate each input branch with a random interest value for learning corresponding image during training. This method can be seen as a stochastic regularization technique, and can further lead to generalization performance improvement. State-of-the-art deep networks can be adapted to dual pattern learning networks without increasing the same number of parameters. Extensive experiments on CIFAR-10, CIFAR- 100, FI-8, Google commands dataset, and MNIST demonstrate that our DPLNets exhibit better performance than original networks. The experimental results on subsets of CIFAR- 10, CIFAR-100, and MNIST demonstrate that dual pattern learning networks have good generalization performance on small datasets.

cs.CV↗

Respond-CAM: Analyzing Deep Models for 3D Imaging Data by Visualizations

The convolutional neural network (CNN) has become a powerful tool for various biomedical image analysis tasks, but there is a lack of visual explanation for the machinery of CNNs. In this paper, we present a novel algorithm, Respond-weighted Class Activation Mapping (Respond-CAM), for making CNN-based models interpretable by visualizing input regions that are important for predictions, especially for biomedical 3D imaging data inputs. Our method uses the gradients of any target concept (e.g. the score of target class) that flows into a convolutional layer. The weighted feature maps are combined to produce a heatmap that highlights the important regions in the image for predicting the target concept. We prove a preferable sum-to-score property of the Respond-CAM and verify its significant improvement on 3D images from the current state-of-the-art approach. Our tests on Cellular Electron Cryo-Tomography 3D images show that Respond-CAM achieves superior performance on visualizing the CNNs with 3D biomedical images inputs, and is able to get reasonably good results on visualizing the CNNs with natural image inputs. The Respond-CAM is an efficient and reliable approach for visualizing the CNN machinery, and is applicable to a wide variety of CNN model families and image analysis tasks.

cs.CV↗