arXiv subjects

Ming-Yueh Huang

Publications and source records attributed to Ming-Yueh Huang.

4 recordsLinked to original sources

arXiv2026

Unsupervised Learning Under a General Semiparametric Clusterwise Elliptical Distribution: Efficient Estimation, Optimal Clustering, and Consistent Cluster Selection

We introduce a general semiparametric clusterwise elliptical distribution to assess how latent cluster structure shapes continuous outcomes. Using a subjectwise representation, we first estimate cluster-specific mean vectors and a cluster-invariant scatter matrix by minimizing a weighted sum of squares criterion augmented with a separation penalty; we provide an initialization scheme and a computational algorithm with guaranteed convergence. This initial estimator consistently recovers the true clusters and seeds a second phase that alternates pseudo-maximum likelihood (or pseudo-maximum marginal likelihood) estimation with cluster reassignment, yielding asymptotic semiparametric efficiency and an optimal clustering that asymptotically maximizes the probability of correct membership. We also propose a semiparametric information criterion for selecting the number of clusters. Monte Carlo simulations and empirical applications demonstrate strong finite-sample performance and practical value.

stat.ME↗

arXiv2026

Integration of Individual Participant and Aggregate Data Under Dataset Shift: Summary Statistic Comparison and Scalable Computation

Integrated IPD-AD analysis, which combines individual participant data (IPD) with aggregate data (AD), is increasingly recognized as an effective strategy for generating more reliable and generalizable inferences from heterogeneous studies. While most existing work has focused on algorithmic approaches, this paper investigates a complementary yet underexplored question: how different forms of AD influence the efficiency of data integration. Working within a constrained maximum likelihood estimation framework, we compare commonly reported summary statistics and show that subgroup-specific summaries can substantially improve estimation efficiency. In particular, we find that AD derived from outcome-stratified subgroups (e.g., cases and controls) consistently yield greater efficiency gains than those based on covariate-stratified subgroups (e.g., age or exposure categories), especially when the outcome is continuous. Although outcome-stratified summaries are commonly reported for discrete outcomes, they are rarely provided when the outcome is continuous. Our findings therefore support the routine inclusion of outcome-stratified summaries for continuous endpoints in trial reports and public data repositories to facilitate more efficient evidence synthesis. We further extend the constrained maximum likelihood framework to accommodate dataset shift and develop a fast, non-iterative estimation procedure to improve numerical stability and scalability. We illustrate the proposed methodology with two applications: an analysis of income data under covariate shift and an analysis of housing data under prior probability shift.

stat.ME↗

arXiv2025

Semiparametric sensitivity analysis: unmeasured confounding in observational studies

Establishing cause-effect relationships from observational data often relies on untestable assumptions. It is crucial to know whether, and to what extent, the conclusions drawn from non-experimental studies are robust to potential unmeasured confounding. In this paper, we focus on the average causal effect (ACE) as our target of inference. We generalize the sensitivity analysis approach developed by Robins et al. (2000), Franks et al. (2020), and Zhou and Yao (2023). We use semiparametric theory to derive the non-parametric efficient influence function of the ACE, for fixed sensitivity parameters. We use this influence function to construct a one-step, split sample, truncated estimator of the ACE. Our estimator depends on semiparametric models for the distribution of the observed data; importantly, these models do not impose any restrictions on the values of sensitivity analysis parameters. We establish sufficient conditions ensuring that our estimator has root-n asymptotics. We use our methodology to evaluate the causal effect of smoking during pregnancy on birth weight. We also evaluate the performance of estimation procedure in a simulation study.

stat.ME↗

arXiv2020

Robust inference of conditional average treatment effects using dimension reduction

It is important to make robust inference of the conditional average treatment effect from observational data, but this becomes challenging when the confounder is multivariate or high-dimensional. In this article, we propose a double dimension reduction method, which reduces the curse of dimensionality as much as possible while keeping the nonparametric merit. We identify the central mean subspace of the conditional average treatment effect using dimension reduction. A nonparametric regression with prior dimension reduction is also used to impute counterfactual outcomes. This step helps improve the stability of the imputation and leads to a better estimator than existing methods. We then propose an effective bootstrapping procedure without bootstrapping the estimated central mean subspace to make valid inference.

stat.ME↗