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Mingbin Ben Feng

Publications and source records attributed to Mingbin Ben Feng.

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Efficient Nested Simulation Experiment Design via the Likelihood Ratio Method

In nested simulation literature, a common assumption is that the experimenter can choose the number of outer scenarios to sample. This paper considers the case when the experimenter is given a fixed set of outer scenarios from an external entity. We propose a nested simulation experiment design that pools inner replications from one scenario to estimate another scenario's conditional mean via the likelihood ratio method. Given the outer scenarios, we decide how many inner replications to run at each outer scenario as well as how to pool the inner replications by solving a bi-level optimization problem that minimizes the total simulation effort. We provide asymptotic analyses on the convergence rates of the performance measure estimators computed from the optimized experiment design. Under some assumptions, the optimized design achieves $\cO(Γ^{-1})$ mean squared error of the estimators given simulation budget $Γ$. Numerical experiments demonstrate that our design outperforms a state-of-the-art design that pools replications via regression.

stat.ME

Green Simulation Assisted Reinforcement Learning with Model Risk for Biomanufacturing Learning and Control

Biopharmaceutical manufacturing faces critical challenges, including complexity, high variability, lengthy lead time, and limited historical data and knowledge of the underlying system stochastic process. To address these challenges, we propose a green simulation assisted model-based reinforcement learning to support process online learning and guide dynamic decision making. Basically, the process model risk is quantified by the posterior distribution. At any given policy, we predict the expected system response with prediction risk accounting for both inherent stochastic uncertainty and model risk. Then, we propose green simulation assisted reinforcement learning and derive the mixture proposal distribution of decision process and likelihood ratio based metamodel for the policy gradient, which can selectively reuse process trajectory outputs collected from previous experiments to increase the simulation data-efficiency, improve the policy gradient estimation accuracy, and speed up the search for the optimal policy. Our numerical study indicates that the proposed approach demonstrates the promising performance.

cs.LG