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Minghui Wang

Publications and source records attributed to Minghui Wang.

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Bioinfoysis Technical Report

Large language model agents have shown promise in bioinformatics, but most existing systems focus primarily on producing final answers, treating planning, tool use, and code execution as transient interactions. This design is poorly suited to long-horizon bioinformatics tasks, where conclusions must remain connected to the data, computations, and intermediate evidence that support them. We introduce \textbf{Bioinfoysis}, a multi-agent harness that represents each request as a persistent, artifact-grounded analysis run. Bioinfoysis combines global planning with step-wise, evidence-driven replanning: the planner maintains an executable checklist and revises pending steps using structured handoffs returned after each worker execution. These handoffs bind intermediate results to their responsible agent, checklist step, and plan generation, preventing stale evidence from being silently reused after replanning. A controlled runtime validates generated scripts, tables, and figures before they are used in downstream analysis or reporting, while role-specific context, persistent memory, and governed bioinformatics skills support reliable execution over long analysis trajectories. We evaluate Bioinfoysis on BixBench and two question-answering tracks of LAB-Bench 2. On BixBench, Bioinfoysis achieves state-of-the-art accuracy of 82.4\%. Across four underlying language models, Bioinfoysis increases average accuracy from 27.81\% to 64.13\% on SeqQA2 and from 3.13\% to 31.25\% on DbQA2. These results demonstrate that reliable bioinformatics automation depends not only on model capability, but also on the harness that governs planning, execution, memory, and evidence flow. We hope that the emergence of Bioinfoysis will play a driving and leading role in the development of the bioinformatics community. Our demo website can be seen in https://report.bioinfoysis.com/.

cs.AI

RxBrain: Embodied Cognition Foundation Model with Joint Language-Visual Reasoning and Imagination

Embodied cognition requires agents to connect high-level task reasoning with the physical states to be achieved. We introduce Hy-Embodied-RxBrain, an embodied cognition foundation model with joint language-visual reasoning and imagination. Unlike vision-language models that emphasize scene understanding and textual decision making, or generative world models that mainly predict future visual states, RxBrain represents embodied plans in a single planning sequence where language and visual imagination play complementary roles. Language provides the abstract structure of a plan, including task decomposition, planning primitives, constraints, temporal order, and decision logic, while visual imagination grounds this structure through world state prediction and joint subgoal planning, associating each planning step with intermediate and final physical states. RxBrain adopts a unified multimodal Mixture-of-Transformers architecture that supports language, image, and video understanding and generation within one model. To train this capability, we build an automatic pipeline that converts embodied videos into joint text-visual planning supervision by decomposing videos into planning steps and aligning them with visual state transitions. We further introduce RxBrain-Bench to evaluate whether models can represent embodied plans through joint textual and visual components rather than separate understanding or generation. Experiments show that RxBrain maintains embodied understanding and generation abilities, and produces plans with coupled textual reasoning, world state prediction, and joint subgoal planning. We also extend RxBrain to continuous robot action generation, where it shows promising real-robot performance without large-scale action-data pretraining. These results provide an initial step toward foundation models for embodied cognition.

cs.AI

Sketching the Readout of Large Language Models for Scalable Data Attribution and Valuation

Data attribution and valuation are critical for understanding data-model synergy for Large Language Models (LLMs), yet existing gradient-based methods suffer from scalability challenges on LLMs. Inspired by human cognition, where decision making relies on a focused readout of relevant memories rather than replaying all pathways, we introduce RISE (Readout Influence Sketching Estimator). Instead of computing and indexing gradients across the entire LLM, RISE focuses on influence hotspots at the output layer, where influence signals concentrate, and the gradient admits a decomposed outer-product form. This enables a dual-channel representation combining a lexical residual channel (RH) and a semantic projected-error channel (GH). Applying CountSketch projections to these channels achieves strong compression while maintaining accurate attribution. Across the OLMo (1B-32B) and Pythia (14M-6.9B) families, RISE reduces index storage by up to 112$\times$ compared to RapidIn and scales to 32B parameters LLM, where gradient-based baselines such as RapidIn and ZO-Inf become memory-infeasible. We evaluate RISE on two paradigms: (1) retrospective attribution, retrieving influential training examples for specific predictions, and (2) prospective valuation, scoring candidate data utility zero-shot. We validate RISE on three tasks: Howdy backdoor data detection, Finance-Medical domain separation, and Brain Rot high-quality data selection. In a closed-loop Brain Rot study, continued pretraining on RISE-selected data yields consistent downstream improvements. Overall, RISE provides a practical and scalable primitive for influence analysis and training-data selection in modern large language models.

cs.LG

HY-Embodied-0.5: Embodied Foundation Models for Real-World Agents

We introduce HY-Embodied-0.5, a family of foundation models specifically designed for real-world embodied agents. To bridge the gap between general Vision-Language Models (VLMs) and the demands of embodied agents, our models are developed to enhance the core capabilities required by embodied intelligence: spatial and temporal visual perception, alongside advanced embodied reasoning for prediction, interaction, and planning. The HY-Embodied-0.5 suite comprises two primary variants: an efficient model with 2B activated parameters designed for edge deployment, and a powerful model with 32B activated parameters targeted for complex reasoning. To support the fine-grained visual perception essential for embodied tasks, we adopt a Mixture-of-Transformers (MoT) architecture to enable modality-specific computing. By incorporating latent tokens, this design effectively enhances the perceptual representation of the models. To improve reasoning capabilities, we introduce an iterative, self-evolving post-training paradigm. Furthermore, we employ on-policy distillation to transfer the advanced capabilities of the large model to the smaller variant, thereby maximizing the performance potential of the compact model. Extensive evaluations across 22 benchmarks, spanning visual perception, spatial reasoning, and embodied understanding, demonstrate the effectiveness of our approach. Our MoT-2B model outperforms similarly sized state-of-the-art models on 16 benchmarks, while the 32B variant achieves performance comparable to frontier models such as Gemini 3.0 Pro. In downstream robot control experiments, we leverage our robust VLM foundation to train an effective Vision-Language-Action (VLA) model, achieving compelling results in real-world physical evaluations. Code and models are open-sourced at https://github.com/Tencent-Hunyuan/HY-Embodied.

cs.CV

Deformation-aware Temporal Generation for Early Prediction of Alzheimers Disease

Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease largely involve analyzing morphological changes in brain images through manual feature extraction. This paper proposes a novel method, the Deformation-Aware Temporal Generative Network (DATGN), to automate the learning of morphological changes in brain images about disease progression for early prediction. Given the common occurrence of missing data in the temporal sequences of MRI images, DATGN initially interpolates incomplete sequences. Subsequently, a bidirectional temporal deformation-aware module guides the network in generating future MRI images that adhere to the disease's progression, facilitating early prediction of Alzheimer's disease. DATGN was tested for the generation of temporal sequences of future MRI images using the ADNI dataset, and the experimental results are competitive in terms of PSNR and MMSE image quality metrics. Furthermore, when DATGN-generated synthetic data was integrated into the SVM vs. CNN vs. 3DCNN-based classification methods, significant improvements were achieved from 6. 21\% to 16\% in AD vs. NC classification accuracy and from 7. 34\% to 21. 25\% in AD vs. MCI vs. NC classification accuracy. The qualitative visualization results indicate that DATGN produces MRI images consistent with the brain atrophy trend in Alzheimer's disease, enabling early disease prediction.

cs.CV

Mask-Robust Face Verification for Online Learning via YOLOv5 and Residual Networks

In the contemporary landscape, the fusion of information technology and the rapid advancement of artificial intelligence have ushered school education into a transformative phase characterized by digitization and heightened intelligence. Concurrently, the global paradigm shift caused by the Covid-19 pandemic has catalyzed the evolution of e-learning, accentuating its significance. Amidst these developments, one pivotal facet of the online education paradigm that warrants attention is the authentication of identities within the digital learning sphere. Within this context, our study delves into a solution for online learning authentication, utilizing an enhanced convolutional neural network architecture, specifically the residual network model. By harnessing the power of deep learning, this technological approach aims to galvanize the ongoing progress of online education, while concurrently bolstering its security and stability. Such fortification is imperative in enabling online education to seamlessly align with the swift evolution of the educational landscape. This paper's focal proposition involves the deployment of the YOLOv5 network, meticulously trained on our proprietary dataset. This network is tasked with identifying individuals' faces culled from images captured by students' open online cameras. The resultant facial information is then channeled into the residual network to extract intricate features at a deeper level. Subsequently, a comparative analysis of Euclidean distances against students' face databases is performed, effectively ascertaining the identity of each student.

cs.CV

Advancing clustering methods in physics education research: A case for mixture models

Clustering methods are often used in physics education research (PER) to identify subgroups of individuals within a population who share similar response patterns or characteristics. K-means (or k-modes, for categorical data) is one of the most commonly used clustering methods in PER. This algorithm, however, is not model-based: it relies on algorithmic partitioning and assigns individuals to subgroups with definite membership. Researchers must also conduct post-hoc analyses to relate subgroup membership to other variables. Mixture models offer a model-based alternative that accounts for classification errors and allows researchers to directly integrate subgroup membership into a broader latent variable framework. In this paper, we outline the theoretical similarities and differences between k-modes clustering and latent class analysis (one type of mixture model for categorical data). We also present parallel analyses using each method to address the same research questions in order to demonstrate these similarities and differences. We provide the data and R code to replicate the worked example presented in the paper for researchers interested in using mixture models.

stat.ME

Multi-Scale Deformable Transformers for Student Learning Behavior Detection in Smart Classroom

The integration of Artificial Intelligence into the modern educational system is rapidly evolving, particularly in monitoring student behavior in classrooms, a task traditionally dependent on manual observation. This conventional method is notably inefficient, prompting a shift toward more advanced solutions like computer vision. However, existing target detection models face significant challenges such as occlusion, blurring, and scale disparity, which are exacerbated by the dynamic and complex nature of classroom settings. Furthermore, these models must adeptly handle multiple target detection. To overcome these obstacles, we introduce the Student Learning Behavior Detection with Multi-Scale Deformable Transformers (SCB-DETR), an innovative approach that utilizes large convolutional kernels for upstream feature extraction, and multi-scale feature fusion. This technique significantly improves the detection capabilities for multi-scale and occluded targets, offering a robust solution for analyzing student behavior. SCB-DETR establishes an end-to-end framework that simplifies the detection process and consistently outperforms other deep learning methods. Employing our custom Student Classroom Behavior (SCBehavior) Dataset, SCB-DETR achieves a mean Average Precision (mAP) of 0.626, which is a 1.5% improvement over the baseline model's mAP and a 6% increase in AP50. These results demonstrate SCB-DETR's superior performance in handling the uneven distribution of student behaviors and ensuring precise detection in dynamic classroom environments.

cs.CV

SideRT: A Real-time Pure Transformer Architecture for Single Image Depth Estimation

Since context modeling is critical for estimating depth from a single image, researchers put tremendous effort into obtaining global context. Many global manipulations are designed for traditional CNN-based architectures to overcome the locality of convolutions. Attention mechanisms or transformers originally designed for capturing long-range dependencies might be a better choice, but usually complicates architectures and could lead to a decrease in inference speed. In this work, we propose a pure transformer architecture called SideRT that can attain excellent predictions in real-time. In order to capture better global context, Cross-Scale Attention (CSA) and Multi-Scale Refinement (MSR) modules are designed to work collaboratively to fuse features of different scales efficiently. CSA modules focus on fusing features of high semantic similarities, while MSR modules aim to fuse features at corresponding positions. These two modules contain a few learnable parameters without convolutions, based on which a lightweight yet effective model is built. This architecture achieves state-of-the-art performances in real-time (51.3 FPS) and becomes much faster with a reasonable performance drop on a smaller backbone Swin-T (83.1 FPS). Furthermore, its performance surpasses the previous state-of-the-art by a large margin, improving AbsRel metric 6.9% on KITTI and 9.7% on NYU. To the best of our knowledge, this is the first work to show that transformer-based networks can attain state-of-the-art performance in real-time in the single image depth estimation field. Code will be made available soon.

cs.CV