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Minghui Zhang

Publications and source records attributed to Minghui Zhang.

69 records · Page 4Linked to original sources

Virtual Coil Augmentation Technology for MR Coil Extrapolation via Deep Learning

Magnetic resonance imaging (MRI) is a widely used medical imaging modality. However, due to the limitations in hardware, scan time, and throughput, it is often clinically challenging to obtain high-quality MR images. In this article, we propose a method of using artificial intelligence to expand the channel to achieve the goal of generating the virtual coils. The main characteristic of our work is utilizing dummy variable technology to expand/extrapolate the receive coils in both image and k-space domains. The high-dimensional information formed by channel expansion is used as the prior information to improve the reconstruction effect of parallel imaging. Two main components are incorporated into the network design, namely variable augmentation technology and sum of squares (SOS) objective function. Variable augmentation provides the network with more high-dimensional prior information, which is helpful for the network to extract the deep feature information of the data. The SOS objective function is employed to solve the deficiency of k-space data training while speeding up convergence. Experimental results demonstrated its great potentials in super-resolution of MR images and accelerated parallel imaging reconstruction.

cs.CV↗

Faithful learning with sure data for lung nodule diagnosis

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First, benign-malignant discrimination is often assessed by human observers without pathologic diagnoses at the nodule level. We termed these data as "unsure data". Second, a classifier does not necessarily acquire reliable nodule features for stable learning and robust prediction with patch-level labels during learning. In this study, we construct a sure dataset with pathologically-confirmed labels and propose a collaborative learning framework to facilitate sure nodule classification by integrating unsure data knowledge through nodule segmentation and malignancy score regression. A loss function is designed to learn reliable features by introducing interpretability constraints regulated with nodule segmentation maps. Furthermore, based on model inference results that reflect the understanding from both machine and experts, we explore a new nodule analysis method for similar historical nodule retrieval and interpretable diagnosis. Detailed experimental results demonstrate that our approach is beneficial for achieving improved performance coupled with faithful model reasoning for lung cancer prediction. Extensive cross-evaluation results further illustrate the effect of unsure data for deep-learning-based methods in lung nodule classification.

eess.IV↗

LTSP: Long-Term Slice Propagation for Accurate Airway Segmentation

Purpose: Bronchoscopic intervention is a widely-used clinical technique for pulmonary diseases, which requires an accurate and topological complete airway map for its localization and guidance. The airway map could be extracted from chest computed tomography (CT) scans automatically by airway segmentation methods. Due to the complex tree-like structure of the airway, preserving its topology completeness while maintaining the segmentation accuracy is a challenging task. Methods: In this paper, a long-term slice propagation (LTSP) method is proposed for accurate airway segmentation from pathological CT scans. We also design a two-stage end-to-end segmentation framework utilizing the LTSP method in the decoding process. Stage 1 is used to generate a coarse feature map by an encoder-decoder architecture. Stage 2 is to adopt the proposed LTSP method for exploiting the continuity information and enhancing the weak airway features in the coarse feature map. The final segmentation result is predicted from the refined feature map. Results: Extensive experiments were conducted to evaluate the performance of the proposed method on 70 clinical CT scans. The results demonstrate the considerable improvements of the proposed method compared to some state-of-the-art methods as most breakages are eliminated and more tiny bronchi are detected. The ablation studies further confirm the effectiveness of the constituents of the proposed method. Conclusion: Slice continuity information is beneficial to accurate airway segmentation. Furthermore, by propagating the long-term slice feature, the airway topology connectivity is preserved with overall segmentation accuracy maintained.

eess.IV↗

BREAK: Bronchi Reconstruction by gEodesic transformation And sKeleton embedding

Airway segmentation is critical for virtual bronchoscopy and computer-aided pulmonary disease analysis. In recent years, convolutional neural networks (CNNs) have been widely used to delineate the bronchial tree. However, the segmentation results of the CNN-based methods usually include many discontinuous branches, which need manual repair in clinical use. A major reason for the breakages is that the appearance of the airway wall can be affected by the lung disease as well as the adjacency of the vessels, while the network tends to overfit to these special patterns in the training set. To learn robust features for these areas, we design a multi-branch framework that adopts the geodesic distance transform to capture the intensity changes between airway lumen and wall. Another reason for the breakages is the intra-class imbalance. Since the volume of the peripheral bronchi may be much smaller than the large branches in an input patch, the common segmentation loss is not sensitive to the breakages among the distal branches. Therefore, in this paper, a breakage-sensitive regularization term is designed and can be easily combined with other loss functions. Extensive experiments are conducted on publicly available datasets. Compared with state-of-the-art methods, our framework can detect more branches while maintaining competitive segmentation performance.

eess.IV↗

Universal Generative Modeling for Calibration-free Parallel Mr Imaging

The integration of compressed sensing and parallel imaging (CS-PI) provides a robust mechanism for accelerating MRI acquisitions. However, most such strategies require the explicit formation of either coil sensitivity profiles or a cross-coil correlation operator, and as a result reconstruction corresponds to solving a challenging bilinear optimization problem. In this work, we present an unsupervised deep learning framework for calibration-free parallel MRI, coined universal generative modeling for parallel imaging (UGM-PI). More precisely, we make use of the merits of both wavelet transform and the adaptive iteration strategy in a unified framework. We train a powerful noise conditional score network by forming wavelet tensor as the network input at the training phase. Experimental results on both physical phantom and in vivo datasets implied that the proposed method is comparable and even superior to state-of-the-art CS-PI reconstruction approaches.

cs.CV↗

FDA: Feature Decomposition and Aggregation for Robust Airway Segmentation

3D Convolutional Neural Networks (CNNs) have been widely adopted for airway segmentation. The performance of 3D CNNs is greatly influenced by the dataset while the public airway datasets are mainly clean CT scans with coarse annotation, thus difficult to be generalized to noisy CT scans (e.g. COVID-19 CT scans). In this work, we proposed a new dual-stream network to address the variability between the clean domain and noisy domain, which utilizes the clean CT scans and a small amount of labeled noisy CT scans for airway segmentation. We designed two different encoders to extract the transferable clean features and the unique noisy features separately, followed by two independent decoders. Further on, the transferable features are refined by the channel-wise feature recalibration and Signed Distance Map (SDM) regression. The feature recalibration module emphasizes critical features and the SDM pays more attention to the bronchi, which is beneficial to extracting the transferable topological features robust to the coarse labels. Extensive experimental results demonstrated the obvious improvement brought by our proposed method. Compared to other state-of-the-art transfer learning methods, our method accurately segmented more bronchi in the noisy CT scans.

eess.IV↗

High-dimensional Assisted Generative Model for Color Image Restoration

This work presents an unsupervised deep learning scheme that exploiting high-dimensional assisted score-based generative model for color image restoration tasks. Considering that the sample number and internal dimension in score-based generative model have key influence on estimating the gradients of data distribution, two different high-dimensional ways are proposed: The channel-copy transformation increases the sample number and the pixel-scale transformation decreases feasible space dimension. Subsequently, a set of high-dimensional tensors represented by these transformations are used to train the network through denoising score matching. Then, sampling is performed by annealing Langevin dynamics and alternative data-consistency update. Furthermore, to alleviate the difficulty of learning high-dimensional representation, a progressive strategy is proposed to leverage the performance. The proposed unsupervised learning and iterative restoration algo-rithm, which involves a pre-trained generative network to obtain prior, has transparent and clear interpretation compared to other data-driven approaches. Experimental results on demosaicking and inpainting conveyed the remarkable performance and diversity of our proposed method.

eess.IV↗

Joint Intensity-Gradient Guided Generative Modeling for Colorization

This paper proposes an iterative generative model for solving the automatic colorization problem. Although previous researches have shown the capability to generate plausible color, the edge color overflow and the requirement of the reference images still exist. The starting point of the unsupervised learning in this study is the observation that the gradient map possesses latent information of the image. Therefore, the inference process of the generative modeling is conducted in joint intensity-gradient domain. Specifically, a set of intensity-gradient formed high-dimensional tensors, as the network input, are used to train a powerful noise conditional score network at the training phase. Furthermore, the joint intensity-gradient constraint in data-fidelity term is proposed to limit the degree of freedom within generative model at the iterative colorization stage, and it is conducive to edge-preserving. Extensive experiments demonstrated that the system outperformed state-of-the-art methods whether in quantitative comparisons or user study.

cs.CV↗

IFR-Net: Iterative Feature Refinement Network for Compressed Sensing MRI

To improve the compressive sensing MRI (CS-MRI) approaches in terms of fine structure loss under high acceleration factors, we have proposed an iterative feature refinement model (IFR-CS), equipped with fixed transforms, to restore the meaningful structures and details. Nevertheless, the proposed IFR-CS still has some limitations, such as the selection of hyper-parameters, a lengthy reconstruction time, and the fixed sparsifying transform. To alleviate these issues, we unroll the iterative feature refinement procedures in IFR-CS to a supervised model-driven network, dubbed IFR-Net. Equipped with training data pairs, both regularization parameter and the utmost feature refinement operator in IFR-CS become trainable. Additionally, inspired by the powerful representation capability of convolutional neural network (CNN), CNN-based inversion blocks are explored in the sparsity-promoting denoising module to generalize the sparsity-enforcing operator. Extensive experiments on both simulated and in vivo MR datasets have shown that the proposed network possesses a strong capability to capture image details and preserve well the structural information with fast reconstruction speed.

cs.LG↗

Denoising Auto-encoding Priors in Undecimated Wavelet Domain for MR Image Reconstruction

Compressive sensing is an impressive approach for fast MRI. It aims at reconstructing MR image using only a few under-sampled data in k-space, enhancing the efficiency of the data acquisition. In this study, we propose to learn priors based on undecimated wavelet transform and an iterative image reconstruction algorithm. At the stage of prior learning, transformed feature images obtained by undecimated wavelet transform are stacked as an input of denoising autoencoder network (DAE). The highly redundant and multi-scale input enables the correlation of feature images at different channels, which allows a robust network-driven prior. At the iterative reconstruction, the transformed DAE prior is incorporated into the classical iterative procedure by the means of proximal gradient algorithm. Experimental comparisons on different sampling trajectories and ratios validated the great potential of the presented algorithm.

eess.IV↗

A numerical investigation on the convergence issues for ghost imaging

The long time consumption is a bottleneck for the applicability of the ghost imaging (GI). By introducing a criterion for the convergence of GI, we investigate a factor that impacts on the convergence speed of it. Based on computer experiments, we demonstrate that the object's feature size relative to the spatial coherent length of the illuminating light impacts on the necessary number of uncorrelated data being acquired for the correlation computation. It may motivate people to seek ways towards real-time practical applications of GI and its analogues. In addition, the method to simulate the uncorrelated sequence of a complex ensemble for thermal light is valuable in applications where actively controlling the light fields is needed.

quant-ph↗

A measurable counterpart to the optical concept of an object

The traditional optical concept for the object does not provide an experimental feasibility to speak for itself, due to the fact that no measuring instrument catches up with the fluctuation of light fields. Using the theory of coherence, we give it a measurable counterpart, and thus to give a satisfactory explanation of what the concept has said. To our knowledge it is the first time to valuate an object in optics in the terms of observable quantities. As a useful example, the applicability to obtain the full knowledge of an object under the partial coherent illuminations is suggested. This work hit the thought which had been advanced by E. Wolf that one measures the correlation function rather than the optical fields themselves. The suggested applicability is a supplementary to the recently found solution to the determination of phases of the diffracted beam.

physics.optics↗

Complex Acquisition of the Fourier Transform Imaging of an Arbitrary Object

A scheme to a complex-valued acquisition of the Fourier transform imaging was proposed. The main idea is to project the real and the imaginary parts of a diffraction field to intensity distributions respectively. The whole procedure was algorithm independent and needs no a priori knowledge of an arbitrary objet. An example was demonstrated with a numerical modeling and its results.

quant-ph↗

Sub-wavelength Coherent Imaging of a Pure-Phase Object with Thermal Light

We report, for the first time, the observation of sub-wavelength coherent image of a pure phase object with thermal light,which represents an accurate Fourier transform. We demonstrate that ghost-imaging scheme (GI) retrieves amplitude transmittance knowledge of objects rather than the transmitted intensities as the HBT-type imaging scheme does.

quant-ph↗

Lensless Fourier-Transform Ghost Imaging with Classical Incoherent Light

The Fourier-Transform ghost imaging of both amplitude-only and pure-phase objects was experimentally observed with classical incoherent light at Fresnel distance by a new lensless scheme. The experimental results are in good agreement with the standard Fourier-transform of the corresponding objects. This scheme provides a new route towards aberration-free diffraction-limited 3D images with classically incoherent thermal light, which have no resolution and depth-of-field limitations of lens-based tomographic systems.

quant-ph↗