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Mingrui Li

Publications and source records attributed to Mingrui Li.

At least 19 recordsLinked to original sources

CryoAtlas: A Large Curated Dataset and Unified Benchmark for Cryo-EM Atomic Model Building

Deep learning has accelerated automated atomic model building from cryo-EM maps, yet progress remains limited by the lack of large, high-quality datasets and standardized evaluation benchmarks. We address this gap by introducing CryoAtlas, a rigorously curated dataset and unified benchmark for density-guided atomic model building of protein chains. By integrating and filtering EMDB and PDB entries (up to March 2026), CryoAtlas provides 17,809 map-model-sequence entries, including a curated 16,657-entry training split. From this resource, we construct a 618-target benchmark with a shared evaluation protocol that jointly assesses structural accuracy, model-to-map fit, and stereochemical validity. Using this framework, we benchmark state-of-the-art learning-based methods against Phenix and AlphaFold3, comprehensively analyzing the impact of map resolution, sequence length, protein category and sequence identity on modeling accuracy. As a case study, retraining the ModelAngelo CNN component on CryoAtlas improves performance on the benchmark. CryoAtlas provides an open, reproducible foundation for future cryo-EM atomic model building research. Project details and resource release updates are available at https://oulling.github.io/cryoatlas/.

cs.AI↗

Learning Air-Ground Motion Control with Temporal Mode Switching and Cross-Terrain Tracking

Passive-wheeled terrestrial-aerial bimodal vehicles (TABVs) combine aerial mobility with energy-efficient ground locomotion. However, reliable air-ground mode switching under limited onboard perception and robust ground trajectory tracking across diverse terrains remain challenging when targeting real-world applications. In this work, we propose a learning-based air-ground motion control framework for passive-wheeled TABVs: 1) a learned mode selector for autonomous air-ground motion mode switching. The selector uses historical single-point time-of-flight (ToF) measurements and robot states together with future reference information to determine the active locomotion mode. 2) a reinforcement learning control policy for trajectory tracking. The policy combines proprioceptive observations with future reference information to anticipate trajectory changes. For ground locomotion, multi-terrain training and dynamics randomization enable robust tracking across different terrains. Simulation and real-world experiments demonstrate reliable air-ground switching under limited perception and accurate ground tracking across diverse terrain conditions. The learned selector outperforms a rule-based mode selector in challenging transitions, while the ground controller achieves lower position RMSE than PID across all tested conditions and maintains decent tracking where NMPC fails. With these capabilities integrated, the system tracks a 101m air-ground trajectory through multiple autonomous mode transitions with a position RMSE of 0.08m.

cs.RO↗

ProtLingo: Efficient Protein Language Modeling via Conditional Memory and Expert Routing

Proteins perform diverse cellular functions, and even single amino-acid substitutions can alter stability, activity, or molecular interactions. Protein language models (PLMs) provide a scalable approach for modeling such sequence--function relationships from unlabeled sequences, but increasing the size of dense Transformer backbones often brings substantial computational cost without consistently improving mutation-sensitive prediction. We introduce ProtLingo, an efficient PLM framework that augments a pretrained single-sequence backbone with conditional local memory and sparse expert routing. ProtLingo maps contextual residue representations into route-specific discrete codes, composes centered local windows into latent $N$-gram addresses, and retrieves reusable residual signals associated with recurring local sequence contexts. In parallel, selected feed-forward blocks are upcycled into sparse Mixture-of-Experts layers with shared and routed experts, enabling residue-dependent computation while activating only a subset of parameters. Experiments on protein fitness prediction, FLIP benchmarks, and supervised contact prediction show that ProtLingo achieves competitive performance with a 150M-scale backbone, including strong parameter efficiency on mutation-effect prediction and preserved long-range structural representations.

cs.AI↗

Extreme Volatility Warning under Label Scarcity via Multi-Source Anomaly Fusion

Early warning of extreme market volatility is central to financial risk management, but actionable events are rare, nonstationary, and often triggered by exogenous information shocks. In our CSI~300 setting, only $\sim$80 positive samples are observed across 791 training days, making heavily supervised multi-source models unstable. We first analyze a 100K-parameter hierarchical text-signal fusion model (HTSF) and find that added parameterization hurts in this low-label regime. Motivated by this failure, we propose \textbf{AAMSF} (Anomaly-Augmented Multi-Signal Fusion), a semisupervised framework that combines Isolation Forest anomaly scores over market indicators, GDELT events, Chinese financial news, and English media with lightweight Ridge score fusion. We further introduce \textbf{T-AAMSF}, a temporal extension for multi-day anomaly accumulation. On CSI~300 (2018--2023), AAMSF achieves test AUC-ROC \textbf{0.680}, outperforming the strongest unsupervised baseline (0.630) and neural baseline (0.588), while T-AAMSF improves PR-AUC to 0.291. Ablations reveal strong source asymmetry: GDELT and domestic financial news provide complementary risk signals, whereas English media consistently reduces performance, and learned weighting is unreliable under validation noise. These results suggest an empirical design principle for label-scarce financial risk warning: robust anomaly geometry and source reliability can matter more than supervised representation capacity.

cs.LG↗

Evolution-Aware MSA Reasoning for Subsampling via Factor Graphs

Multiple Sequence Alignments (MSAs) provide protein language models with explicit evolutionary context, but their large depth makes subsampling unavoidable under limited token budgets. Existing strategies, including random selection, identity-based filtering, and diversity-driven sampling, are effective heuristics, yet provide limited control over the evolutionary signals retained in the subset. In this work, we recast MSA subsampling as an explicit optimization problem, where key evolutionary measures, including query identity and diversity, are treated as controllable objectives. Building on this view, we introduce AP-REASONER, an Affinity-Propagation-based factor-graph approach. With evolution-aware unary factors, exemplar-consistency factors, and two control knobs, AP-REASONER performs factor-graph reasoning through message passing to infer a fixed-budget MSA subset. Experiments on long-range contact prediction and conformational ensemble prediction show that AP-REASONER outperforms baseline subsamplers on structure-sensitive downstream tasks and enables controllable recovery of alternative protein conformations. These results highlight the value of modeling MSA subsampling as a controllable optimization problem, where factor-graph reasoning offers an effective alternative to heuristic selection.

cs.LG↗

CryoACE: An Atom-centric Framework for Accurate and Automated Model Building in Cryo-EM

Protein automodeling from cryo-EM density maps faces unique challenges in enforcing physicochemical validity and managing conformational heterogeneity. Current solvers are often limited to static predictions or require computationally intensive heuristic searches. We present CryoACE, an end-to-end framework that reconstructs precise atomic graphs for both homogeneous and heterogeneous structures. Our method features two key innovations: an atom-centric reconstruction paradigm, where density features are sampled directly at atomic coordinates and iteratively recycled to refine structures, replacing expensive voxel convolutions for efficient multimodal fusion; and a training-free guidance mechanism that leverages predicted local resolution priors to resolve dynamic ambiguity. Validated on a newly constructed high-quality dataset, CryoACE significantly outperforms existing baselines on static benchmarks and, for the first time, unveils atomic-level dynamic conformations on complex real-world datasets like EMPIAR-10345 without relying on pre-built static structures.

cs.AI↗

MyGO-Splat: Multi-Objective Closed-Loop Geometric Feedback for RGB-Only Gaussian SLAM

Real-time monocular Simultaneous Localization and Mapping (SLAM) fundamentally suffers from scale ambiguity and a lack of geometric self-correction. While 3D Gaussian Splatting (3DGS) enables high-fidelity rendering, existing RGB-only systems remain open-loop because depth priors are injected into mapping but refined geometry cannot effectively regulate tracking drift. We present MyGO-Splat, a closed-loop Gaussian SLAM framework that analytically rasterizes Gaussian primitives into pixel-wise depth and surface normals, allowing the map to actively supervise camera pose optimization. To bridge monocular priors and scale consistency, our framework introduces scale-aware adaptive alignment that projects foundation-model depth estimates into the globally optimized Gaussian space, forming a self-correcting cycle for scale feedback. Extensive evaluations show that this closed-loop design improves scale stability and appearance-geometry consistency, achieving performance comparable to RGB-D methods while using only monocular input.

cs.RO↗

Morphology-Aware Graph Reinforcement Learning for Tensegrity Robot Locomotion

Tensegrity robots combine rigid rods and elastic cables, offering high resilience and deployability but at the same time posing major challenges for locomotion control due to their underactuated and highly coupled dynamics. This paper introduces a morphology-aware reinforcement learning framework that integrates a graph neural network (GNN) into the Soft Actor-Critic (SAC) algorithm. By representing the robot's physical topology as a graph, the proposed GNN-based policy captures coupling among components, enabling faster and more stable learning than conventional multilayer perceptron (MLP) policies. The method is validated on a physical 3-bar tensegrity robot across three locomotion primitives, including straight-line tracking and bidirectional turning. It shows superior sample efficiency, robustness to noise and stiffness variations, and improved trajectory accuracy. Additionally, the learned policies transfer directly from simulation to hardware without fine-tuning, achieving stable real-world locomotion. These results demonstrate the advantages of incorporating structural priors into reinforcement learning for tensegrity robot control.

cs.RO↗

Beyond Self-Play: Hierarchical Reasoning for Continuous Motion in Closed-Loop Traffic Simulation

Closed-loop traffic simulation requires agents that are both scalable and behaviorally realistic. Recent self-play reinforcement learning approaches demonstrate strong scalability, but their equilibrium strategies fail to capture the socially aware behaviors of real human drivers. We propose a hierarchical architecture that goes beyond self-play by combining high-level multi-agent interaction reasoning with low-level continuous trajectory realization. Specifically, a Stackelberg-style Multi-Agent Reinforcement Learning (MARL) module generates interaction-aware intention commands. These commands condition a low-level continuous motion module, translating the strategic intent into physically consistent, scene-responsive control sequences. To mitigate distribution shift in closed-loop deployment, we introduce a hybrid co-training scheme combining MARL with auxiliary recovery supervision. Experiments on a SUMO-based urban network demonstrate that the proposed framework achieves superior control smoothness and safety compared to self-play and passive imitation baselines, while maintaining competitive traffic efficiency.

cs.RO↗

NTIRE 2026 3D Restoration and Reconstruction in Real-world Adverse Conditions: RealX3D Challenge Results

This paper presents a comprehensive review of the NTIRE 2026 3D Restoration and Reconstruction (3DRR) Challenge, detailing the proposed methods and results. The challenge seeks to identify robust reconstruction pipelines that are robust under real-world adverse conditions, specifically extreme low-light and smoke-degraded environments, as captured by our RealX3D benchmark. A total of 279 participants registered for the competition, of whom 33 teams submitted valid results. We thoroughly evaluate the submitted approaches against state-of-the-art baselines, revealing significant progress in 3D reconstruction under adverse conditions. Our analysis highlights shared design principles among top-performing methods and provides insights into effective strategies for handling 3D scene degradation.

cs.CV↗

Enantiopurity-Controlled Magnetism in a Two-Dimensional Organic-Inorganic Material

Extended solids that combine unpaired electron spin and structural chirality can host unconventional magnetic behaviors with potential for electronic technologies. A versatile strategy for creating chiral solids is incorporation of chiral organic molecules into inorganic crystals. However, such hybrid organic-inorganic materials have so far been examined through the lens of absolute chirality, leaving enantiomeric excess (ee) underexplored as a tuning parameter. Here, we report two-dimensional (2D) intercalation compounds with controllable ee produced by cation exchange of MnPS$_3$ with chiral organic molecules. We show that these materials' magnetism is determined by intercalant ee rather than absolute chirality. Moreover, low-ee materials display thermally activated dynamic magnetism absent from enantiopure analogs. These ee-dependent magnetic behaviors are explained by local ordering of Mn vacancies, directed by correlated vacancy-intercalant electrostatics and confined molecular packing. Together, these results demonstrate a distinctive tuning strategy for molecule-material hybrids and establish design principles for 2D chiral and magnetically dynamic materials.

cond-mat.mtrl-sci↗

MG-SLAM: Structure Gaussian Splatting SLAM with Manhattan World Hypothesis

Gaussian Splatting SLAMs have made significant advancements in improving the efficiency and fidelity of real-time reconstructions. However, these systems often encounter incomplete reconstructions in complex indoor environments, characterized by substantial holes due to unobserved geometry caused by obstacles or limited view angles. To address this challenge, we present Manhattan Gaussian SLAM, an RGB-D system that leverages the Manhattan World hypothesis to enhance geometric accuracy and completeness. By seamlessly integrating fused line segments derived from structured scenes, our method ensures robust tracking in textureless indoor areas. Moreover, The extracted lines and planar surface assumption allow strategic interpolation of new Gaussians in regions of missing geometry, enabling efficient scene completion. Extensive experiments conducted on both synthetic and real-world scenes demonstrate that these advancements enable our method to achieve state-of-the-art performance, marking a substantial improvement in the capabilities of Gaussian SLAM systems.

cs.RO↗

What Is The Best 3D Scene Representation for Robotics? From Geometric to Foundation Models

In this paper, we provide a comprehensive overview of existing scene representation methods for robotics, covering traditional representations such as point clouds, voxels, signed distance functions (SDF), and scene graphs, as well as more recent neural representations like Neural Radiance Fields (NeRF), 3D Gaussian Splatting (3DGS), and the emerging Foundation Models. While current SLAM and localization systems predominantly rely on sparse representations like point clouds and voxels, dense scene representations are expected to play a critical role in downstream tasks such as navigation and obstacle avoidance. Moreover, neural representations such as NeRF, 3DGS, and foundation models are well-suited for integrating high-level semantic features and language-based priors, enabling more comprehensive 3D scene understanding and embodied intelligence. In this paper, we categorized the core modules of robotics into five parts (Perception, Mapping, Localization, Navigation, Manipulation). We start by presenting the standard formulation of different scene representation methods and comparing the advantages and disadvantages of scene representation across different modules. This survey is centered around the question: What is the best 3D scene representation for robotics? We then discuss the future development trends of 3D scene representations, with a particular focus on how the 3D Foundation Model could replace current methods as the unified solution for future robotic applications. The remaining challenges in fully realizing this model are also explored. We aim to offer a valuable resource for both newcomers and experienced researchers to explore the future of 3D scene representations and their application in robotics. We have published an open-source project on GitHub and will continue to add new works and technologies to this project.

cs.RO↗

DenseSplat: Densifying Gaussian Splatting SLAM with Neural Radiance Prior

Gaussian SLAM systems excel in real-time rendering and fine-grained reconstruction compared to NeRF-based systems. However, their reliance on extensive keyframes is impractical for deployment in real-world robotic systems, which typically operate under sparse-view conditions that can result in substantial holes in the map. To address these challenges, we introduce DenseSplat, the first SLAM system that effectively combines the advantages of NeRF and 3DGS. DenseSplat utilizes sparse keyframes and NeRF priors for initializing primitives that densely populate maps and seamlessly fill gaps. It also implements geometry-aware primitive sampling and pruning strategies to manage granularity and enhance rendering efficiency. Moreover, DenseSplat integrates loop closure and bundle adjustment, significantly enhancing frame-to-frame tracking accuracy. Extensive experiments on multiple large-scale datasets demonstrate that DenseSplat achieves superior performance in tracking and mapping compared to current state-of-the-art methods.

cs.CV↗

STG-Avatar: Animatable Human Avatars via Spacetime Gaussian

Realistic animatable human avatars from monocular videos are crucial for advancing human-robot interaction and enhancing immersive virtual experiences. While recent research on 3DGS-based human avatars has made progress, it still struggles with accurately representing detailed features of non-rigid objects (e.g., clothing deformations) and dynamic regions (e.g., rapidly moving limbs). To address these challenges, we present STG-Avatar, a 3DGS-based framework for high-fidelity animatable human avatar reconstruction. Specifically, our framework introduces a rigid-nonrigid coupled deformation framework that synergistically integrates Spacetime Gaussians (STG) with linear blend skinning (LBS). In this hybrid design, LBS enables real-time skeletal control by driving global pose transformations, while STG complements it through spacetime adaptive optimization of 3D Gaussians. Furthermore, we employ optical flow to identify high-dynamic regions and guide the adaptive densification of 3D Gaussians in these regions. Experimental results demonstrate that our method consistently outperforms state-of-the-art baselines in both reconstruction quality and operational efficiency, achieving superior quantitative metrics while retaining real-time rendering capabilities. Our code is available at https://github.com/jiangguangan/STG-Avatar

cs.CV↗

Dy3DGS-SLAM: Monocular 3D Gaussian Splatting SLAM for Dynamic Environments

Current Simultaneous Localization and Mapping (SLAM) methods based on Neural Radiance Fields (NeRF) or 3D Gaussian Splatting excel in reconstructing static 3D scenes but struggle with tracking and reconstruction in dynamic environments, such as real-world scenes with moving elements. Existing NeRF-based SLAM approaches addressing dynamic challenges typically rely on RGB-D inputs, with few methods accommodating pure RGB input. To overcome these limitations, we propose Dy3DGS-SLAM, the first 3D Gaussian Splatting (3DGS) SLAM method for dynamic scenes using monocular RGB input. To address dynamic interference, we fuse optical flow masks and depth masks through a probabilistic model to obtain a fused dynamic mask. With only a single network iteration, this can constrain tracking scales and refine rendered geometry. Based on the fused dynamic mask, we designed a novel motion loss to constrain the pose estimation network for tracking. In mapping, we use the rendering loss of dynamic pixels, color, and depth to eliminate transient interference and occlusion caused by dynamic objects. Experimental results demonstrate that Dy3DGS-SLAM achieves state-of-the-art tracking and rendering in dynamic environments, outperforming or matching existing RGB-D methods.

cs.CV↗

NGM-SLAM: Gaussian Splatting SLAM with Radiance Field Submap

SLAM systems based on Gaussian Splatting have garnered attention due to their capabilities for rapid real-time rendering and high-fidelity mapping. However, current Gaussian Splatting SLAM systems usually struggle with large scene representation and lack effective loop closure detection. To address these issues, we introduce NGM-SLAM, the first 3DGS based SLAM system that utilizes neural radiance field submaps for progressive scene expression, effectively integrating the strengths of neural radiance fields and 3D Gaussian Splatting. We utilize neural radiance field submaps as supervision and achieve high-quality scene expression and online loop closure adjustments through Gaussian rendering of fused submaps. Our results on multiple real-world scenes and large-scale scene datasets demonstrate that our method can achieve accurate hole filling and high-quality scene expression, supporting monocular, stereo, and RGB-D inputs, and achieving state-of-the-art scene reconstruction and tracking performance.

cs.RO↗

LLGS: Unsupervised Gaussian Splatting for Image Enhancement and Reconstruction in Pure Dark Environment

3D Gaussian Splatting has shown remarkable capabilities in novel view rendering tasks and exhibits significant potential for multi-view optimization.However, the original 3D Gaussian Splatting lacks color representation for inputs in low-light environments. Simply using enhanced images as inputs would lead to issues with multi-view consistency, and current single-view enhancement systems rely on pre-trained data, lacking scene generalization. These problems limit the application of 3D Gaussian Splatting in low-light conditions in the field of robotics, including high-fidelity modeling and feature matching. To address these challenges, we propose an unsupervised multi-view stereoscopic system based on Gaussian Splatting, called Low-Light Gaussian Splatting (LLGS). This system aims to enhance images in low-light environments while reconstructing the scene. Our method introduces a decomposable Gaussian representation called M-Color, which separately characterizes color information for targeted enhancement. Furthermore, we propose an unsupervised optimization method with zero-knowledge priors, using direction-based enhancement to ensure multi-view consistency. Experiments conducted on real-world datasets demonstrate that our system outperforms state-of-the-art methods in both low-light enhancement and 3D Gaussian Splatting.

cs.CV↗