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Mingrui Luo

Publications and source records attributed to Mingrui Luo.

3 recordsLinked to original sources

ScienceCUA: Resource-to-Skill Construction and Execution-Guided Skill Evolution for Scientific Computer Use Agents

Computer-use agents for scientific software require application-specific expertise. Much of this expertise is documented in human-authored software manuals and web pages. However, turning these resources into executable, reusable skills remains challenging due to mismatches between documented and deployed software versions and differences in scope between documentation coverage and task requirements. We introduce ScienceCUA, a two-stage framework combining resource-to-skill construction with execution-guided skill evolution. First, ScienceCUA identifies tasks supported by the software from its documentation, infers operational trajectories, and generalizes them into reusable Skills. Command catalogs, syntax constraints, and shortcuts are organized separately as References for on-demand lookup. Then, ScienceCUA uses execution feedback to drive skill self-evolution by contrasting successful and failed trajectories for the same task, identifying deficiencies, revising existing skills or adding new ones, and updating the skill library only after repeated validation in real environments. To enable reliable evaluation without benchmark noise or task leakage, we introduce two improved benchmarks. ScienceBoard-Verified provides an audited and corrected basis for measuring task performance, while ScienceBoard-VE separates skill evolution from final testing through disjoint evolution and test tasks and further supports native-agent evaluation. Experiments show that the initial Skills and References improve average task success rate by up to 7.23 percentage points over the base model, while skill self-evolution increases the total gain over the baseline to as much as 17.12 percentage points. ScienceCUA turns software documentation into an evolving set of executable skills and queryable references, offering a practical way for general-purpose agents to use scientific software reliably and at scale.

cs.AI↗

Bioinfoysis Technical Report

Large language model agents have shown promise in bioinformatics, but most existing systems focus primarily on producing final answers, treating planning, tool use, and code execution as transient interactions. This design is poorly suited to long-horizon bioinformatics tasks, where conclusions must remain connected to the data, computations, and intermediate evidence that support them. We introduce \textbf{Bioinfoysis}, a multi-agent harness that represents each request as a persistent, artifact-grounded analysis run. Bioinfoysis combines global planning with step-wise, evidence-driven replanning: the planner maintains an executable checklist and revises pending steps using structured handoffs returned after each worker execution. These handoffs bind intermediate results to their responsible agent, checklist step, and plan generation, preventing stale evidence from being silently reused after replanning. A controlled runtime validates generated scripts, tables, and figures before they are used in downstream analysis or reporting, while role-specific context, persistent memory, and governed bioinformatics skills support reliable execution over long analysis trajectories. We evaluate Bioinfoysis on BixBench and two question-answering tracks of LAB-Bench 2. On BixBench, Bioinfoysis achieves state-of-the-art accuracy of 82.4\%. Across four underlying language models, Bioinfoysis increases average accuracy from 27.81\% to 64.13\% on SeqQA2 and from 3.13\% to 31.25\% on DbQA2. These results demonstrate that reliable bioinformatics automation depends not only on model capability, but also on the harness that governs planning, execution, memory, and evidence flow. We hope that the emergence of Bioinfoysis will play a driving and leading role in the development of the bioinformatics community. Our demo website can be seen in https://report.bioinfoysis.com/.

cs.AI↗

FARM: Reading Failure Signals from the Internal Predictive States of a Frozen Robotic World Model

Reliable robot deployment requires online failure monitoring, yet existing monitors mainly derive risk from proxy signals or train dedicated monitoring components. We ask whether the internal predictive states of a frozen pretrained robotic world model already contain directly decodable failure information. Failure-Aware Readout from World Models (FARM) trains only a 33,985-parameter supervised readout over frozen VLA-JEPA predictive states, producing step-wise failure scores and causal trajectory risk. Five-fold out-of-fold evaluation across seven source tasks reaches 85.68/88.59 pooled AUROC/AUPRC, and FARM gives the best Seen performance among 15 matched baselines on the 10-task benchmark. Across four real-robot populations on PIPER X, SO-101, and Franka, fixed-readout transfer and readout-only adaptation test deployment shifts without updating the predictive backbone. FARM also discriminates failures from partial causal histories and adds 0.2256 ms mean CUDA latency once the frozen state is available. These results support frozen predictive world-model states as reusable features for causal, transferable, and low-overhead execution monitoring.

cs.RO↗