arXiv subjects

Mohammad Mahdi Danesh Pajouh

Publications and source records attributed to Mohammad Mahdi Danesh Pajouh.

3 recordsLinked to original sources

arXiv2026

Multi-Stage Prompt-Guided Feature Modulation for Generalizable Brain Tumor Segmentation

Accurate brain tumor segmentation from magnetic resonance imaging (MRI) is essential for diagnosis, treatment planning, surgical guidance, and disease monitoring. However, developing automated segmentation models that generalize across diverse tumor characteristics, imaging protocols, acquisition sites, and patient populations remains challenging. Variations in tumor morphology and imaging distributions can substantially degrade performance outside the training domain. Consequently, improving the robustness and generalization of deep learning-based segmentation models has become a key objective in medical image analysis. To improve segmentation robustness, we propose Multi-Stage Dynamic Prompt nnU-Net, a prompt-conditioned extension of nnU-Net. Three independent dynamic prompt modules are inserted into the deepest encoder stages. Each module contains a learnable bank of ten 256-dimensional prompt vectors and uses globally pooled encoder features to generate image-specific prompt representations. These representations are projected into feature-wise scaling $(γ)$ and shifting $(β)$ parameters that modulate encoder feature maps through Feature-wise Linear Modulation (FiLM), enabling adaptive feature conditioning at multiple semantic levels. Evaluation on the BraTS GOAT validation dataset demonstrated that the proposed Multi-Stage Dynamic Prompt nnU-Net outperformed the baseline nnU Net across the majority of evaluated metrics and tumor subregions. The proposed model achieved average lesion-wise Dice scores of 76.16% (ET), 80.04% (TC), and 86.42% (WT), compared with 74.38%, 78.14% and 84.01% for the baseline model. The results demonstrate that multi-stage dynamic prompt conditioning improves segmentation accuracy and boundary delineation for brain tumor segmentation.

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arXiv2025

Efficient Meningioma Tumor Segmentation Using Ensemble Learning

Meningiomas represent the most prevalent form of primary brain tumors, comprising nearly one-third of all diagnosed cases. Accurate delineation of these tumors from MRI scans is crucial for guiding treatment strategies, yet remains a challenging and time-consuming task in clinical practice. Recent developments in deep learning have accelerated progress in automated tumor segmentation; however, many advanced techniques are hindered by heavy computational demands and long training schedules, making them less accessible for researchers and clinicians working with limited hardware. In this work, we propose a novel ensemble-based segmentation approach that combines three distinct architectures: (1) a baseline SegResNet model, (2) an attention-augmented SegResNet with concatenative skip connections, and (3) a dual-decoder U-Net enhanced with attention-gated skip connections (DDUNet). The ensemble aims to leverage architectural diversity to improve robustness and accuracy while significantly reducing training demands. Each baseline model was trained for only 20 epochs and Evaluated on the BraTS-MEN 2025 dataset. The proposed ensemble model achieved competitive performance, with average Lesion-Wise Dice scores of 77.30%, 76.37% and 73.9% on test dataset for Enhancing Tumor (ET), Tumor Core (TC) and Whole Tumor (WT) respectively. These results highlight the effectiveness of ensemble learning for brain tumor segmentation, even under limited hardware constraints. Our proposed method provides a practical and accessible tool for aiding the diagnosis of meningioma, with potential impact in both clinical and research settings.

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arXiv2025

Efficient Brain Tumor Segmentation Using a Dual-Decoder 3D U-Net with Attention Gates (DDUNet)

Cancer remains one of the leading causes of mortality worldwide, and among its many forms, brain tumors are particularly notorious due to their aggressive nature and the critical challenges involved in early diagnosis. Recent advances in artificial intelligence have shown great promise in assisting medical professionals with precise tumor segmentation, a key step in timely diagnosis and treatment planning. However, many state-of-the-art segmentation methods require extensive computational resources and prolonged training times, limiting their practical application in resource-constrained settings. In this work, we present a novel dual-decoder U-Net architecture enhanced with attention-gated skip connections, designed specifically for brain tumor segmentation from MRI scans. Our approach balances efficiency and accuracy by achieving competitive segmentation performance while significantly reducing training demands. Evaluated on the BraTS 2020 dataset, the proposed model achieved Dice scores of 85.06% for Whole Tumor (WT), 80.61% for Tumor Core (TC), and 71.26% for Enhancing Tumor (ET) in only 50 epochs, surpassing several commonly used U-Net variants. Our model demonstrates that high-quality brain tumor segmentation is attainable even under limited computational resources, thereby offering a viable solution for researchers and clinicians operating with modest hardware. This resource-efficient model has the potential to improve early detection and diagnosis of brain tumors, ultimately contributing to better patient outcomes

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