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Moi Hoon Yap

Publications and source records attributed to Moi Hoon Yap.

At least 37 records · Page 2Linked to original sources

Diabetic Foot Ulcer Grand Challenge 2021: Evaluation and Summary

Diabetic foot ulcer classification systems use the presence of wound infection (bacteria present within the wound) and ischaemia (restricted blood supply) as vital clinical indicators for treatment and prediction of wound healing. Studies investigating the use of automated computerised methods of classifying infection and ischaemia within diabetic foot wounds are limited due to a paucity of publicly available datasets and severe data imbalance in those few that exist. The Diabetic Foot Ulcer Challenge 2021 provided participants with a more substantial dataset comprising a total of 15,683 diabetic foot ulcer patches, with 5,955 used for training, 5,734 used for testing and an additional 3,994 unlabelled patches to promote the development of semi-supervised and weakly-supervised deep learning techniques. This paper provides an evaluation of the methods used in the Diabetic Foot Ulcer Challenge 2021, and summarises the results obtained from each network. The best performing network was an ensemble of the results of the top 3 models, with a macro-average F1-score of 0.6307.

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FacialGAN: Style Transfer and Attribute Manipulation on Synthetic Faces

Facial image manipulation is a generation task where the output face is shifted towards an intended target direction in terms of facial attribute and styles. Recent works have achieved great success in various editing techniques such as style transfer and attribute translation. However, current approaches are either focusing on pure style transfer, or on the translation of predefined sets of attributes with restricted interactivity. To address this issue, we propose FacialGAN, a novel framework enabling simultaneous rich style transfers and interactive facial attributes manipulation. While preserving the identity of a source image, we transfer the diverse styles of a target image to the source image. We then incorporate the geometry information of a segmentation mask to provide a fine-grained manipulation of facial attributes. Finally, a multi-objective learning strategy is introduced to optimize the loss of each specific tasks. Experiments on the CelebA-HQ dataset, with CelebAMask-HQ as semantic mask labels, show our model's capacity in producing visually compelling results in style transfer, attribute manipulation, diversity and face verification. For reproducibility, we provide an interactive open-source tool to perform facial manipulations, and the Pytorch implementation of the model.

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Analysis Towards Classification of Infection and Ischaemia of Diabetic Foot Ulcers

This paper introduces the Diabetic Foot Ulcers dataset (DFUC2021) for analysis of pathology, focusing on infection and ischaemia. We describe the data preparation of DFUC2021 for ground truth annotation, data curation and data analysis. The final release of DFUC2021 consists of 15,683 DFU patches, with 5,955 training, 5,734 for testing and 3,994 unlabeled DFU patches. The ground truth labels are four classes, i.e. control, infection, ischaemia and both conditions. We curate the dataset using image hashing techniques and analyse the separability using UMAP projection. We benchmark the performance of five key backbones of deep learning, i.e. VGG16, ResNet101, InceptionV3, DenseNet121 and EfficientNet on DFUC2021. We report the optimised results of these key backbones with different strategies. Based on our observations, we conclude that EfficientNetB0 with data augmentation and transfer learning provided the best results for multi-class (4-class) classification with macro-average Precision, Recall and F1-score of 0.57, 0.62 and 0.55, respectively. In ischaemia and infection recognition, when trained on one-versus-all, EfficientNetB0 achieved comparable results with the state of the art. Finally, we interpret the results with statistical analysis and Grad-CAM visualisation.

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Deep Learning in Diabetic Foot Ulcers Detection: A Comprehensive Evaluation

There has been a substantial amount of research involving computer methods and technology for the detection and recognition of diabetic foot ulcers (DFUs), but there is a lack of systematic comparisons of state-of-the-art deep learning object detection frameworks applied to this problem. DFUC2020 provided participants with a comprehensive dataset consisting of 2,000 images for training and 2,000 images for testing. This paper summarises the results of DFUC2020 by comparing the deep learning-based algorithms proposed by the winning teams: Faster R-CNN, three variants of Faster R-CNN and an ensemble method; YOLOv3; YOLOv5; EfficientDet; and a new Cascade Attention Network. For each deep learning method, we provide a detailed description of model architecture, parameter settings for training and additional stages including pre-processing, data augmentation and post-processing. We provide a comprehensive evaluation for each method. All the methods required a data augmentation stage to increase the number of images available for training and a post-processing stage to remove false positives. The best performance was obtained from Deformable Convolution, a variant of Faster R-CNN, with a mean average precision (mAP) of 0.6940 and an F1-Score of 0.7434. Finally, we demonstrate that the ensemble method based on different deep learning methods can enhanced the F1-Score but not the mAP.

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DFUC2020: Analysis Towards Diabetic Foot Ulcer Detection

Every 20 seconds, a limb is amputated somewhere in the world due to diabetes. This is a global health problem that requires a global solution. The MICCAI challenge discussed in this paper, which concerns the automated detection of diabetic foot ulcers using machine learning techniques, will accelerate the development of innovative healthcare technology to address this unmet medical need. In an effort to improve patient care and reduce the strain on healthcare systems, recent research has focused on the creation of cloud-based detection algorithms. These can be consumed as a service by a mobile app that patients (or a carer, partner or family member) could use themselves at home to monitor their condition and to detect the appearance of a diabetic foot ulcer (DFU). Collaborative work between Manchester Metropolitan University, Lancashire Teaching Hospital and the Manchester University NHS Foundation Trust has created a repository of 4,000 DFU images for the purpose of supporting research toward more advanced methods of DFU detection. Based on a joint effort involving the lead scientists of the UK, US, India and New Zealand, this challenge will solicit original work, and promote interactions between researchers and interdisciplinary collaborations. This paper presents a dataset description and analysis, assessment methods, benchmark algorithms and initial evaluation results. It facilitates the challenge by providing useful insights into state-of-the-art and ongoing research. This grand challenge takes on even greater urgency in a peri and post-pandemic period, where stresses on resource utilization will increase the need for technology that allows people to remain active, healthy and intact in their home.

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A Cloud-based Deep Learning Framework for Remote Detection of Diabetic Foot Ulcers

This research proposes a mobile and cloud-based framework for the automatic detection of diabetic foot ulcers and conducts an investigation of its performance. The system uses a cross-platform mobile framework which enables the deployment of mobile apps to multiple platforms using a single TypeScript code base. A deep convolutional neural network was deployed to a cloud-based platform where the mobile app could send photographs of patient's feet for inference to detect the presence of diabetic foot ulcers. The functionality and usability of the system were tested in two clinical settings: Salford Royal NHS Foundation Trust and Lancashire Teaching Hospitals NHS Foundation Trust. The benefits of the system, such as the potential use of the app by patients to identify and monitor their condition are discussed.

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Foreground-guided Facial Inpainting with Fidelity Preservation

Facial image inpainting, with high-fidelity preservation for image realism, is a very challenging task. This is due to the subtle texture in key facial features (component) that are not easily transferable. Many image inpainting techniques have been proposed with outstanding capabilities and high quantitative performances recorded. However, with facial inpainting, the features are more conspicuous and the visual quality of the blended inpainted regions are more important qualitatively. Based on these facts, we design a foreground-guided facial inpainting framework that can extract and generate facial features using convolutional neural network layers. It introduces the use of foreground segmentation masks to preserve the fidelity. Specifically, we propose a new loss function with semantic capability reasoning of facial expressions, natural and unnatural features (make-up). We conduct our experiments using the CelebA-HQ dataset, segmentation masks from CelebAMask-HQ (for foreground guidance) and Quick Draw Mask (for missing regions). Our proposed method achieved comparable quantitative results when compare to the state of the art but qualitatively, it demonstrated high-fidelity preservation of facial components.

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Deep learning in magnetic resonance prostate segmentation: A review and a new perspective

Prostate radiotherapy is a well established curative oncology modality, which in future will use Magnetic Resonance Imaging (MRI)-based radiotherapy for daily adaptive radiotherapy target definition. However the time needed to delineate the prostate from MRI data accurately is a time consuming process. Deep learning has been identified as a potential new technology for the delivery of precision radiotherapy in prostate cancer, where accurate prostate segmentation helps in cancer detection and therapy. However, the trained models can be limited in their application to clinical setting due to different acquisition protocols, limited publicly available datasets, where the size of the datasets are relatively small. Therefore, to explore the field of prostate segmentation and to discover a generalisable solution, we review the state-of-the-art deep learning algorithms in MR prostate segmentation; provide insights to the field by discussing their limitations and strengths; and propose an optimised 2D U-Net for MR prostate segmentation. We evaluate the performance on four publicly available datasets using Dice Similarity Coefficient (DSC) as performance metric. Our experiments include within dataset evaluation and cross-dataset evaluation. The best result is achieved by composite evaluation (DSC of 0.9427 on Decathlon test set) and the poorest result is achieved by cross-dataset evaluation (DSC of 0.5892, Prostate X training set, Promise 12 testing set). We outline the challenges and provide recommendations for future work. Our research provides a new perspective to MR prostate segmentation and more importantly, we provide standardised experiment settings for researchers to evaluate their algorithms. Our code is available at https://github.com/AIEMMU/MRI\_Prostate.

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R-MNet: A Perceptual Adversarial Network for Image Inpainting

Facial image inpainting is a problem that is widely studied, and in recent years the introduction of Generative Adversarial Networks, has led to improvements in the field. Unfortunately some issues persists, in particular when blending the missing pixels with the visible ones. We address the problem by proposing a Wasserstein GAN combined with a new reverse mask operator, namely Reverse Masking Network (R-MNet), a perceptual adversarial network for image inpainting. The reverse mask operator transfers the reverse masked image to the end of the encoder-decoder network leaving only valid pixels to be inpainted. Additionally, we propose a new loss function computed in feature space to target only valid pixels combined with adversarial training. These then capture data distributions and generate images similar to those in the training data with achieved realism (realistic and coherent) on the output images. We evaluate our method on publicly available dataset, and compare with state-of-the-art methods. We show that our method is able to generalize to high-resolution inpainting task, and further show more realistic outputs that are plausible to the human visual system when compared with the state-of-the-art methods.

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Symmetric Skip Connection Wasserstein GAN for High-Resolution Facial Image Inpainting

The state-of-the-art facial image inpainting methods achieved promising results but face realism preservation remains a challenge. This is due to limitations such as; failures in preserving edges and blurry artefacts. To overcome these limitations, we propose a Symmetric Skip Connection Wasserstein Generative Adversarial Network (S-WGAN) for high-resolution facial image inpainting. The architecture is an encoder-decoder with convolutional blocks, linked by skip connections. The encoder is a feature extractor that captures data abstractions of an input image to learn an end-to-end mapping from an input (binary masked image) to the ground-truth. The decoder uses learned abstractions to reconstruct the image. With skip connections, S-WGAN transfers image details to the decoder. Additionally, we propose a Wasserstein-Perceptual loss function to preserve colour and maintain realism on a reconstructed image. We evaluate our method and the state-of-the-art methods on CelebA-HQ dataset. Our results show S-WGAN produces sharper and more realistic images when visually compared with other methods. The quantitative measures show our proposed S-WGAN achieves the best Structure Similarity Index Measure (SSIM) of 0.94.

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Anysize GAN: A solution to the image-warping problem

We propose a new type of General Adversarial Network (GAN) to resolve a common issue with Deep Learning. We develop a novel architecture that can be applied to existing latent vector based GAN structures that allows them to generate on-the-fly images of any size. Existing GAN for image generation requires uniform images of matching dimensions. However, publicly available datasets, such as ImageNet contain thousands of different sizes. Resizing image causes deformations and changing the image data, whereas as our network does not require this preprocessing step. We make significant changes to the standard data loading techniques to enable any size image to be loaded for training. We also modify the network in two ways, by adding multiple inputs and a novel dynamic resizing layer. Finally we make adjustments to the discriminator to work on multiple resolutions. These changes can allow multiple resolution datasets to be trained on without any resizing, if memory allows. We validate our results on the ISIC 2019 skin lesion dataset. We demonstrate our method can successfully generate realistic images at different sizes without issue, preserving and understanding spatial relationships, while maintaining feature relationships. We will release the source codes upon paper acceptance.

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Spotting Macro- and Micro-expression Intervals in Long Video Sequences

This paper presents baseline results for the Third Facial Micro-Expression Grand Challenge (MEGC 2020). Both macro- and micro-expression intervals in CAS(ME)$^2$ and SAMM Long Videos are spotted by employing the method of Main Directional Maximal Difference Analysis (MDMD). The MDMD method uses the magnitude maximal difference in the main direction of optical flow features to spot facial movements. The single-frame prediction results of the original MDMD method are post-processed into reasonable video intervals. The metric F1-scores of baseline results are evaluated: for CAS(ME)$^2$, the F1-scores are 0.1196 and 0.0082 for macro- and micro-expressions respectively, and the overall F1-score is 0.0376; for SAMM Long Videos, the F1-scores are 0.0629 and 0.0364 for macro- and micro-expressions respectively, and the overall F1-score is 0.0445. The baseline project codes are publicly available at https://github.com/HeyingGithub/Baseline-project-for-MEGC2020_spotting.

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Multi-class Semantic Segmentation of Skin Lesions via Fully Convolutional Networks

Melanoma is clinically difficult to distinguish from common benign skin lesions, particularly melanocytic naevus and seborrhoeic keratosis. The dermoscopic appearance of these lesions has huge intra-class variations and high inter-class visual similarities. Most current research is focusing on single-class segmentation irrespective of classes of skin lesions. In this work, we evaluate the performance of deep learning on multi-class segmentation of ISIC-2017 challenge dataset, which consists of 2,750 dermoscopic images. We propose an end-to-end solution using fully convolutional networks (FCNs) for multi-class semantic segmentation to automatically segment the melanoma, seborrhoeic keratosis and naevus. To improve the performance of FCNs, transfer learning and a hybrid loss function are used. We evaluate the performance of the deep learning segmentation methods for multi-class segmentation and lesion diagnosis (with post-processing method) on the testing set of the ISIC-2017 challenge dataset. The results showed that the two-tier level transfer learning FCN-8s achieved the overall best result with \textit{Dice} score of 78.5% in a naevus category, 65.3% in melanoma, and 55.7% in seborrhoeic keratosis in multi-class segmentation and Accuracy of 84.62% for recognition of melanoma in lesion diagnosis.

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SAMM Long Videos: A Spontaneous Facial Micro- and Macro-Expressions Dataset

With the growth of popularity of facial micro-expressions in recent years, the demand for long videos with micro- and macro-expressions remains high. Extended from SAMM, a micro-expressions dataset released in 2016, this paper presents SAMM Long Videos dataset for spontaneous micro- and macro-expressions recognition and spotting. SAMM Long Videos dataset consists of 147 long videos with 343 macro-expressions and 159 micro-expressions. The dataset is FACS-coded with detailed Action Units (AUs). We compare our dataset with Chinese Academy of Sciences Macro-Expressions and Micro-Expressions (CAS(ME)2) dataset, which is the only available fully annotated dataset with micro- and macro-expressions. Furthermore, we preprocess the long videos using OpenFace, which includes face alignment and detection of facial AUs. We conduct facial expression spotting using this dataset and compare it with the baseline of MEGC III. Our spotting method outperformed the baseline result with F1-score of 0.3299.

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Recognition of Ischaemia and Infection in Diabetic Foot Ulcers: Dataset and Techniques

Recognition and analysis of Diabetic Foot Ulcers (DFU) using computerized methods is an emerging research area with the evolution of image-based machine learning algorithms. Existing research using visual computerized methods mainly focuses on recognition, detection, and segmentation of the visual appearance of the DFU as well as tissue classification. According to DFU medical classification systems, the presence of infection (bacteria in the wound) and ischaemia (inadequate blood supply) has important clinical implications for DFU assessment, which are used to predict the risk of amputation. In this work, we propose a new dataset and computer vision techniques to identify the presence of infection and ischaemia in DFU. This is the first time a DFU dataset with ground truth labels of ischaemia and infection cases is introduced for research purposes. For the handcrafted machine learning approach, we propose a new feature descriptor, namely the Superpixel Color Descriptor. Then we use the Ensemble Convolutional Neural Network (CNN) model for more effective recognition of ischaemia and infection. We propose to use a natural data-augmentation method, which identifies the region of interest on foot images and focuses on finding the salient features existing in this area. Finally, we evaluate the performance of our proposed techniques on binary classification, i.e. ischaemia versus non-ischaemia and infection versus non-infection. Overall, our method performed better in the classification of ischaemia than infection. We found that our proposed Ensemble CNN deep learning algorithms performed better for both classification tasks as compared to handcrafted machine learning algorithms, with 90% accuracy in ischaemia classification and 73% in infection classification.

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Automatic Lesion Boundary Segmentation in Dermoscopic Images with Ensemble Deep Learning Methods

Early detection of skin cancer, particularly melanoma, is crucial to enable advanced treatment. Due to the rapid growth in the numbers of skin cancers, there is a growing need of computerized analysis for skin lesions. The state-of-the-art public available datasets for skin lesions are often accompanied with very limited amount of segmentation ground truth labeling as it is laborious and expensive. The lesion boundary segmentation is vital to locate the lesion accurately in dermoscopic images and lesion diagnosis of different skin lesion types. In this work, we propose the use of fully automated deep learning ensemble methods for accurate lesion boundary segmentation in dermoscopic images. We trained the Mask-RCNN and DeepLabv3+ methods on ISIC-2017 segmentation training set and evaluate the performance of the ensemble networks on ISIC-2017 testing set. Our results showed that the best proposed ensemble method segmented the skin lesions with Jaccard index of 79.58% for the ISIC-2017 testing set. The proposed ensemble method outperformed FrCN, FCN, U-Net, and SegNet in Jaccard Index by 2.48%, 7.42%, 17.95%, and 9.96% respectively. Furthermore, the proposed ensemble method achieved an accuracy of 95.6% for some representative clinically benign cases, 90.78% for the melanoma cases, and 91.29% for the seborrheic keratosis cases on ISIC-2017 testing set, exhibiting better performance than FrCN, FCN, U-Net, and SegNet.

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Spotting Micro-Expressions on Long Videos Sequences

This paper presents baseline results for the first Micro-Expression Spotting Challenge 2019 by evaluating local temporal pattern (LTP) on SAMM and CAS(ME)2. The proposed LTP patterns are extracted by applying PCA in a temporal window on several facial local regions. The micro-expression sequences are then spotted by a local classification of LTP and a global fusion. The performance is evaluated by Leave-One-Subject-Out cross validation. Furthermore, we define the criteria of determining true positives in one video by overlap rate and set the metric F1-score for spotting performance of the whole database. The F1-score of baseline results for SAMM and CAS(ME)2 are 0.0316 and 0.0179, respectively.

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Semantic Segmentation of Human Thigh Quadriceps Muscle in Magnetic Resonance Images

This paper presents an end-to-end solution for MRI thigh quadriceps segmentation. This is the first attempt that deep learning methods are used for the MRI thigh segmentation task. We use the state-of-the-art Fully Convolutional Networks with transfer learning approach for the semantic segmentation of regions of interest in MRI thigh scans. To further improve the performance of the segmentation, we propose a post-processing technique using basic image processing methods. With our proposed method, we have established a new benchmark for MRI thigh quadriceps segmentation with mean Jaccard Similarity Index of 0.9502 and processing time of 0.117 second per image.

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