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Monica Pirani

Publications and source records attributed to Monica Pirani.

3 recordsLinked to original sources

A Bayesian Multisource Fusion Model for Spatiotemporal PM2.5 in an Urban Setting

Airborne particulate matter (PM2.5) is a major public health concern in urban environments, where population density and emission sources exacerbate exposure risks. We present a novel Bayesian spatiotemporal fusion model to estimate monthly PM2.5 concentrations over Greater London (2014-2019) at 1km resolution. The model integrates multiple PM2.5 data sources, including outputs from two atmospheric air quality dispersion models and predictive variables, such as vegetation and satellite aerosol optical depth, while explicitly modelling a latent spatiotemporal field. Spatial misalignment of the data is addressed through an upscaling approach to predict across the entire area. Building on stochastic partial differential equations (SPDE) within the integrated nested Laplace approximations (INLA) framework, our method introduces spatially- and temporally-varying coefficients to flexibly calibrate datasets and capture fine-scale variability. Model performance and complexity are balanced using predictive metrics such as the predictive model choice criterion and thorough cross-validation. The best performing model shows excellent fit and solid predictive performance, enabling reliable high-resolution spatiotemporal mapping of PM2.5 concentrations with the associated uncertainty. Furthermore, the model outputs, including full posterior predictive distributions, can be used to map exceedance probabilities of regulatory thresholds, supporting air quality management and targeted interventions in vulnerable urban areas, as well as providing refined exposure estimates of PM2.5 for epidemiological applications.

stat.ME

A framework for estimating and visualising excess mortality during the COVID-19 pandemic

COVID-19 related deaths underestimate the pandemic burden on mortality because they suffer from completeness and accuracy issues. Excess mortality is a popular alternative, as it compares observed with expected deaths based on the assumption that the pandemic did not occur. Expected deaths had the pandemic not occurred depend on population trends, temperature, and spatio-temporal patterns. In addition to this, high geographical resolution is required to examine within country trends and the effectiveness of the different public health policies. In this tutorial, we propose a framework using R to estimate and visualise excess mortality at high geographical resolution. We show a case study estimating excess deaths during 2020 in Italy. The proposed framework is fast to implement and allows combining different models and presenting the results in any age, sex, spatial and temporal aggregation desired. This makes it particularly powerful and appealing for online monitoring of the pandemic burden and timely policy making.

stat.AP

A hierarchical modelling approach to assess multi pollutant effects in time-series studies

When assessing the short term effect of air pollution on health outcomes, it is common practice to consider one pollutant at a time, due to their high correlation. Multi pollutant methods have been recently proposed, mainly consisting of collapsing the different pollutants into air quality indexes or clustering the pollutants and then evaluating the effect of each cluster on the health outcome. A major drawback of such approaches is that it is not possible to evaluate the health impact of each pollutant. In this paper we propose the use of the Bayesian hierarchical framework to deal with multi pollutant concentration in a two-component model: a pollutant model is specified to estimate the `true' concentration values for if your each pollutant and then such concentration is linked to the health outcomes in a time series perspective. Through a simulation study we evaluate the model performance and we apply the modelling framework to investigate the effect of six pollutants on cardiovascular mortality in Greater London in 2011-2012.

stat.AP