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Montie Avery

Publications and source records attributed to Montie Avery.

At least 19 recordsLinked to original sources

Coherent dynamics in soft-threshold integrate-and-fire networks

We study bifurcations in networks of integrate-and-fire neurons with stochastic spike emission, focusing on the effects of the spatial and temporal structure of the synaptic interactions. Using a deterministic mean-field approximation of the population dynamics, we characterize spatial, temporal, and spatiotemporal patterns of macroscopic activity. In the mean-field theory, synaptic delays give rise to uniform oscillations across the population through a subcritical Hopf bifurcation of the stationary uniform equilibrium. With local excitation and long-range inhibition the network undergoes a Turing bifurcation, resulting in a localized area of sustained activity, or stationary bump. When the coupling has both delays, local inhibition, and long range excitation, the network undergoes a Turing-Hopf bifurcation leading to spatiotemporal dynamics, such as standing and traveling waves. When multiple instabilities are excited, we observe other complex spatiotemporal dynamics. We confirm all these predictions of the mean-field theory in simulations of the underlying stochastic model.

q-bio.NC

Selection mechanisms in front invasion

We review progress on questions related to front propagation into unstable states and point out open problems in the area. We strive to highlight different theoretical perspectives and challenges while also addressing more practical questions with examples and guides to computational methods. Throughout we take a dynamical systems point of view that focuses on the ability of invasion processes to act as a selection mechanism in complex systems.

math.AP

Selection of pushed pattern-forming fronts in the FitzHugh-Nagumo system

We establish nonlinear stability of fronts that describe the creation of a periodic pattern through the invasion of an unstable state. Our results concern pushed fronts, that is, fronts whose propagation is driven by a localized mode at the front interface. We prove that these pushed pattern-forming fronts attract initial data supported on a half-line, and therefore determine both propagation speeds and selected wave numbers for invasion from localized initial conditions. This provides to our knowledge the first proof of the marginal stability conjecture for pattern-forming fronts, thereby confirming universal wave number selection laws widely used in the physics literature. We present our analysis in the specific setting of the FitzHugh-Nagumo system, but our methods can be applied to general dissipative PDE models which exhibit pattern formation. The main technical challenge is to control the interaction between the localized mode driving the propagation and outgoing diffusive modes in the wake of the front. Through a subtle far-field/core decomposition of the linearized evolution, we resolve this interaction and describe the nonlinear response of the front to perturbations as a dynamically driven phase mixing problem for the pattern in the wake. The methods we develop are generally useful in any setting involving the interaction of localized modes and outward diffusive transport, such as in the nonlinear stability of undercompressive viscous shock waves or source defects.

math.AP

Stability of coherent pattern formation through invasion in the FitzHugh-Nagumo system

We establish sharp nonlinear stability results for fronts that describe the creation of a periodic pattern through the invasion of an unstable state. The fronts we consider are critical, in the sense that they are expected to mediate pattern selection from compactly supported or steep initial data. We focus on pulled fronts, that is, on fronts whose propagation speed is determined by the linearization about the unstable state in the leading edge, only. We present our analysis in the specific setting of the FitzHugh-Nagumo system, where pattern-forming uniformly translating fronts have recently been constructed rigorously, but our methods can be used to establish nonlinear stability of pulled pattern-forming fronts in general reaction-diffusion systems. This is the first stability result of critical pattern-selecting fronts and provides a rigorous foundation for heuristic, universal wave number selection laws in growth processes based on a marginal stability conjecture. The main technical challenge is to describe the interaction between two separate modes of marginal stability, one associated with the spreading process in the leading edge, and one associated with the pattern in the wake. We develop tools based on far-field/core decompositions to characterize, and eventually control, the interaction between these two different types of diffusive modes. Linear decay rates are insufficient to close a nonlinear stability argument and we therefore need a sharper description of the relaxation in the wake of the front using a phase modulation ansatz. We control regularity in the resulting quasilinear equation for the modulated perturbation using nonlinear damping estimates.

math.AP

Diffusive synchronization of phase waves in the FitzHugh-Nagumo system

We analyze synchronization of relaxation oscillations in multiple-timescale reaction-diffusion systems. Interpreting synchronization as convergence to frequency-synchronized wave-train solutions, we resolve for the first time the case of phase waves. These waves are nearly phase-synchronized relaxation oscillations, featuring quasistationary plateaus of length $\varepsilon^{-1}$ separated by fast transition layers, where $\varepsilon\ll1$ is the timescale separation parameter. Tracking the decay of modulations via a Bloch-wave eigenfunction analysis, we find a remarkably weak interaction strength of order $\varepsilon^{8/3}$. This weak layer interaction and many of the technical difficulties arise from repeated scattering of eigenfunctions through fold points at the ends of the quasistationary plateaus. We capture this by combining a novel geometric desingularization approach with Lin's method, exponential trichotomies, and the Riccati transform. While our spectral stability analysis yields diffusive synchronization of all phase waves in the FitzHugh-Nagumo system, it also identifies potential finite-wavelength instabilities, which we realize in a system variant.

math.AP

Pulled fronts are not (just) pulled

Front propagation into unstable states is often determined by the linearization, that is, propagation speeds agree with predictions from the linearized equation at the unstable state. The leading edge behavior is then a Gaussian tail propagating with the linear spreading speed. Fronts following this leading edge are commonly referred to as pulled fronts, alluding to the idea that they are ``pulled'' by this leading-edge Gaussian tail. We describe here a class of examples that exhibits how these leading-order effects do not completely describe the dynamics in the wake of the front. In fact, leading edge behavior predicts at most two possible invasion scenarios, associated with positive and negative amplitudes of the Gaussian tail, but our examples exhibit three or more invasion fronts with different states in the wake. The resulting invasion process therefore leaves behind a state that is not solely determined by the leading edge, and thus not just pulled by the Gaussian tail.

math.AP

Fronts and patterns with a dynamic parameter ramp

We examine the effect of a slowly-varying time-dependent parameter on invasion fronts for which an unstable homogeneous equilibrium is invaded by either another homogeneous state or a spatially periodic state. We first explain and motivate our approach by studying asymptotically constant invasion fronts in a scalar FKPP equation with time-dependent parameter which controls the stability of the trivial state. Following recent works in the area, we use a linearized analysis to derive formal predictions for front position and leading-edge spatial decay. We then use a comparison principle approach to establish a rigorous spreading result in the case of an unbounded temporal parameter. We then consider patterned-invasion in the complex Ginzburg-Landau equation with dynamic bifurcation parameter, a prototype for slow passage through a spatio-temporal Hopf instability. Linearized analysis once again gives front position and decay asymptotics, but also the selected spatial wavenumber at the leading edge. We then use a Burger's modulation analysis to predict the slowly-varying wavenumber in the wake of the front. Finally, in both equations, we used the recently developed concept of a space-time memory curve to characterize delayed invasion in the case where the parameter is initially stable before a subsequent slow passage through instability and invasion. We also provide preliminary results studying invasion in other prototypical pattern formation models modified with a dynamic parameter, as well as numerical results for delayed transition between pushed and pulled fronts in Nagumo's equation with dynamic parameter.

nlin.PS

Slow passage through the Busse balloon -- predicting steps on the Eckhaus staircase

Motivated by the impact of worsening climate conditions on vegetation patches, we study dynamic instabilities in an idealized Ginzburg-Landau model. Our main results predict time instances of sudden drops in wavenumber and the resulting target states. The changes in wavenumber correspond to the annihilation of individual vegetation patches when resources are scarce and cannot support the original number of patches. Drops happen well after the primary pattern has destabilized at the Eckhaus boundary and key to distinguishing between the disappearance of 1,2, or more patches during the drop are complex spatio-temporal resonances in the linearization at the unstable pattern. We support our results with numerical simulations and expect our results to be conceptually applicable universally near the Eckhaus boundary, in particular in more realistic models.

nlin.AO

Growth of cancer stem cell driven tumors: staged invasion, linear determinacy, and the tumor invasion paradox

We study growth of solid tumors in a partial differential equation model introduced by Hillen et al for the interaction between tumor cells (TCs) and cancer stem cells (CSCs). We find that invasion into the cancer-free state may be separated into two regimes, depending on the death rate of tumor cells. In the first, staged invasion regime, invasion into the cancer-free state is lead by tumor cells, which are then subsequently invaded at a slower speed by cancer stem cells. In the second, TC extinction regime, cancer stem cells directly invade the cancer-free state. Relying on recent results establishing front selection propagation under marginal stability assumptions, we use geometric singular perturbation theory to establish existence and selection properties of front solutions which describe both the primary and secondary invasion processes. With rigorous predictions for the invasion speeds, we are then able to heuristically predict how the total cancer mass as a function of time depends on the TC death rate, finding in some situations a tumor invasion paradox, in which increasing the TC death rate leads to an increase in the total cancer mass. Our methods give a general approach for verifying linear determinacy of spreading speeds of invasion fronts in systems with fast-slow structure.

math.AP

Front selection in reaction-diffusion systems via diffusive normal forms

We show that propagation speeds in invasion processes modeled by reaction-diffusion systems are determined by marginal spectral stability conditions, as predicted by the marginal stability conjecture. This conjecture was recently settled in scalar equations; here we give a full proof for the multi-component case. The main new difficulty lies in precisely characterizing diffusive dynamics in the leading edge of invasion fronts. To overcome this, we introduce coordinate transformations which allow us to recognize a leading order diffusive equation relying only on an assumption of generic marginal pointwise stability. We are then able to use self-similar variables to give a detailed description of diffusive dynamics in the leading edge, which we match with a traveling invasion front in the wake. We then establish front selection by controlling these matching errors in a nonlinear iteration scheme, relying on sharp estimates on the linearization about the invasion front. We briefly discuss applications to parametrically forced amplitude equations, competitive Lotka-Volterra systems, and a tumor growth model.

math.AP

Front propagation close to the onset of instability

We describe the resulting spatiotemporal dynamics when a homogeneous equilibrium loses stability in a spatially extended system. More precisely, we consider reaction-diffusion systems, assuming only that the reaction kinetics undergo a transcritical, saddle-node, or supercritical pitchfork bifurcation as a parameter passes through zero. We construct traveling front solutions which describe the invasion of the now-unstable state by a nearby stable state. We show that these fronts are marginally spectrally stable near the bifurcation point, which, together with recent advances in the theory of front propagation into unstable states, establishes that these fronts govern the dynamics of localized perturbation to the unstable state. Our proofs are based on functional analytic tools to study the existence and eigenvalue problems for fronts, which become singularly perturbed after a natural rescaling.

math.AP

Pushed and pulled fronts in a logistic Keller-Segel model with chemorepulsion

We analyze spatial spreading in a population model with logistic growth and chemorepulsion. In a parameter range of short-range chemo-diffusion, we use geometric singular perturbation theory and functional-analytic farfield-core decompositions to identify spreading speeds with marginally stable front profiles. In particular, we identify a sharp boundary between between linearly determined, pulled propagation, and nonlinearly determined, pushed propagation, induced by the chemorepulsion. The results are motivated by recent work on singular limits in this regime using PDE methods.

math.AP

Pushed-to-pulled front transitions: continuation, speed scalings, and hidden monotonicity

We analyze the transition between pulled and pushed fronts both analytically and numerically from a model-independent perspective. Based on minimal conceptual assumptions, we show that pushed fronts bifurcate from a branch of pulled fronts with an effective speed correction that scales quadratically in the bifurcation parameter. Strikingly, we find that in this general context without assumptions on comparison principles, the pulled front loses stability and gives way to a pushed front when monotonicity in the leading edge is lost. Our methods rely on far-field core decompositions that identify explicitly asymptotics in the leading edge of the front. We show how the theoretical construction can be directly implemented to yield effective algorithms that determine spreading speeds and bifurcation points with exponentially small error in the domain size. Example applications considered here include an extended Fisher-KPP equation, a Fisher-Burgers equation, negative taxis in combination with logistic population growth, an autocatalytic reaction, and a Lotka-Volterra model.

math.AP

Universal selection of pulled fronts

We establish selection of critical pulled fronts in invasion processes. Our result shows convergence to a pulled front with a logarithmic shift for open sets of steep initial data, including one-sided compactly supported initial conditions. We rely on robust, conceptual assumptions, namely existence and marginal spectral stability of a front traveling at the linear spreading speed. We demonstrate that the assumptions hold for open classes of spatially extended systems. Previous results relied on comparison principles or probabilistic tools with implied non-open conditions on initial data and structure of the equation. Technically, we describe the invasion process through the interaction of a Gaussian leading edge with the pulled front in the wake. Key ingredients are sharp linear decay estimates to control errors in the nonlinear matching and corrections from initial data.

math.AP

Spectral stability of the critical front in the extended Fisher-KPP equation

We revisit the existence and stability of the critical front in the extended Fisher-KPP equation, refining earlier results of Rottschäfer and Wayne [28] which establish stability of fronts without identifying a precise decay rate. We verify that the front is marginally spectrally stable: while the essential spectrum touches the imaginary axis at the origin, there are no unstable eigenvalues and no eigenvalue (or resonance) embedded in the essential spectrum at the origin. Together with the recent work of Avery and Scheel [3], this implies nonlinear stability of the critical front with sharp $t^{-3/2}$ decay rate, as previously obtained in the classical Fisher-KPP equation. The main challenges are to regularize the singular perturbation in the extended Fisher-KPP equation and to track eigenvalues near the essential spectrum, and we overcome these difficulties with functional analytic methods.

math.AP

Sharp decay rates for localized perturbations to the critical front in the Ginzburg-Landau equation

We revisit the nonlinear stability of the critical invasion front in the Ginzburg-Landau equation. Our main result shows that the amplitude of localized perturbations decays with rate $t^{-3/2}$, while the phase decays diffusively. We thereby refine earlier work of Bricmont and Kupiainen as well as Eckmann and Wayne, who separately established nonlinear stability but with slower decay rates. On a technical level, we rely on sharp linear estimates obtained through analysis of the resolvent near the essential spectrum via a far-field/core decomposition which is well suited to accurately describing the dynamics of separate neutrally stable modes arising from far-field behavior on the left and right.

math.AP

Instability in large bounded domains -- branched versus unbranched resonances

We study transitions from convective to absolute instability near a trivial state in large bounded domains for prototypical model problems in the presence of transport and negative nonlinear feedback. We identify two generic scenarios, depending on the nature of the linear mechanism for instability, which both lead to different, universal bifurcation diagrams. In the first, classical case of a linear branched resonance the transition is hard, that is, small changes in a control parameter lead to a finite-size state. In the second, novel case of an unbranched resonance, the transition is gradual. In both cases, the bifurcation diagram is determined by interaction of the leading edge of an invasion front with upstream boundary conditions. Technically, we analyze this interaction in a heteroclinic gluing bifurcation analysis that uses geometric desingularization of the trivial state.

nlin.PS

Asymptotic stability of critical pulled fronts via resolvent expansions near the essential spectrum

We study nonlinear stability of pulled fronts in scalar parabolic equations on the real line of arbitrary order, under conceptual assumptions on existence and spectral stability of fronts. In this general setting, we establish sharp algebraic decay rates and temporal asymptotics of perturbations to the front. Some of these results are known for the specific example of the Fisher-KPP equation, and our results can thus be viewed as establishing universality of some aspects of this simple model. We also give a precise description of how the spatial localization of perturbations to the front affects the temporal decay rate, across the full range of localizations for which asymptotic stability holds. Technically, our approach is based on a detailed study of the resolvent operator for the linearized problem, through which we obtain sharp linear time decay estimates that allow for a direct nonlinear analysis.

math.AP