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Moritz Ladenburger

Publications and source records attributed to Moritz Ladenburger.

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HASSL: Hierarchy-Aware Self-Supervised Learning Framework for Single Cell Microscopy

Hierarchical structure is common in image data, where fine-grained clusters often merge into larger, coarser semantic groups. In biological cell images, current self-supervised learning models often suppress this hierarchy, as coarse factors such as imaging modality can obscure finer morphological attributes in the latent space. We propose a hierarchy-aware self-supervised training framework to address this problem. Our method combines two components: a distillation framework with a segmentation teacher to improve morphological awareness in the latent space, and a hierarchy-aware contrastive loss based on HDBSCAN to improve decision boundaries between closely related subtypes at different hierarchical levels. Together, these components reduce the tendency of self-supervised learning to overemphasize coarse factors and instead align embeddings with semantic and morphological cues. This yields biologically meaningful sub-clusters driven by fine morphological detail. We train and evaluate our method on a curated corpus of 2.3 million single cells aggregated from 20 microscopy datasets, both labeled and unlabeled, covering 208 cell classes. Our method improves over baseline and counterpart methods, increasing average top-K accuracy by 2.8%, top-9 retrieval on the dataset with the deepest hierarchy by 6.3%, and downstream F1-score for biologically relevant drug classification from perturbed cell morphology by 7.8%.

cs.CV

A Coin Flip for Safety: LLM Judges Fail to Reliably Measure Adversarial Robustness

Automated \enquote{LLM-as-a-Judge} frameworks have become the de facto standard for scalable evaluation across natural language processing. For instance, in safety evaluation, these judges are relied upon to evaluate harmfulness in order to benchmark the robustness of safety against adversarial attacks. However, we show that existing validation protocols fail to account for substantial distribution shifts inherent to red-teaming: diverse victim models exhibit distinct generation styles, attacks distort output patterns, and semantic ambiguity varies significantly across jailbreak scenarios. Through a comprehensive audit using 6642 human-verified labels, we reveal that the unpredictable interaction of these shifts often causes judge performance to degrade to near random chance. This stands in stark contrast to the high human agreement reported in prior work. Crucially, we find that many attacks inflate their success rates by exploiting judge insufficiencies rather than eliciting genuinely harmful content. To enable more reliable evaluation, we propose ReliableBench, a benchmark of behaviors that remain more consistently judgeable, and JudgeStressTest, a dataset designed to expose judge failures. Data available at: https://github.com/SchwinnL/LLMJudgeReliability.

cs.CL

AdversariaLLM: A Unified and Modular Toolbox for LLM Robustness Research

The rapid expansion of research on Large Language Model (LLM) safety and robustness has produced a fragmented and oftentimes buggy ecosystem of implementations, datasets, and evaluation methods. This fragmentation makes reproducibility and comparability across studies challenging, hindering meaningful progress. To address these issues, we introduce AdversariaLLM, a toolbox for conducting LLM jailbreak robustness research. Its design centers on reproducibility, correctness, and extensibility. The framework implements twelve adversarial attack algorithms, integrates seven benchmark datasets spanning harmfulness, over-refusal, and utility evaluation, and provides access to a wide range of open-weight LLMs via Hugging Face. The implementation includes advanced features for comparability and reproducibility such as compute-resource tracking, deterministic results, and distributional evaluation techniques. \name also integrates judging through the companion package JudgeZoo, which can also be used independently. Together, these components aim to establish a robust foundation for transparent, comparable, and reproducible research in LLM safety.

cs.AI