arXiv subjects

Mriganka Sur

Publications and source records attributed to Mriganka Sur.

3 recordsLinked to original sources

arXiv2021

Evidence of Task-Independent Person-Specific Signatures in EEG using Subspace Techniques

Electroencephalography (EEG) signals are promising as alternatives to other biometrics owing to their protection against spoofing. Previous studies have focused on capturing individual variability by analyzing task/condition-specific EEG. This work attempts to model biometric signatures independent of task/condition by normalizing the associated variance. Toward this goal, the paper extends ideas from subspace-based text-independent speaker recognition and proposes novel modifications for modeling multi-channel EEG data. The proposed techniques assume that biometric information is present in the entire EEG signal and accumulate statistics across time in a high dimensional space. These high dimensional statistics are then projected to a lower dimensional space where the biometric information is preserved. The lower dimensional embeddings obtained using the proposed approach are shown to be task-independent. The best subspace system identifies individuals with accuracies of 86.4% and 35.9% on datasets with 30 and 920 subjects, respectively, using just nine EEG channels. The paper also provides insights into the subspace model's scalability to unseen tasks and individuals during training and the number of channels needed for subspace modeling.

eess.SP↗

arXiv2017

A computational study on synaptic and extrasynaptic effects of astrocyte glutamate uptake on orientation tuning in V1

Astrocytes affect neural transmission by a tight control via glutamate transporters on glutamate concentrations in direct vicinity to the synaptic cleft and by extracellular glutamate. Their relevance for information representation has been supported by in-vivo studies in ferret and mouse primary visual cortex. In ferret blocking glutamate transport pharmacologically broadened tuning curves and enhanced the response at preferred orientation. In knock-out mice with reduced expression of glutamate transporters sharpened tuning was observed. It is however unclear how focal and ambient changes in glutamate concentration affect stimulus representation. Here we develop a computational framework, which allows the investigation of synaptic and extrasynaptic effects of glutamate uptake on orientation tuning in recurrently connected network models with pinwheel-domain (ferret) or salt-and-pepper (mouse) organization. This model proposed that glutamate uptake shapes information representation when it affects the contribution of excitatory and inhibitory neurons to the network activity. Namely, strengthening the contribution of excitatory neurons generally broadens tuning and elevates the response. In contrast, strengthening the contribution of inhibitory neurons can have a sharpening effect on tuning. In addition local representational topology also plays a role: In the pinwheel-domain model effects were strongest within domains - regions where neighboring neurons share preferred orientations. Around pinwheels but also within salt-and-pepper networks the effects were less strong. Our model proposes that the pharmacological intervention in ferret increases the contribution of excitatory cells, while the reduced expression in mouse increases the contribution of inhibitory cells to network activity.

q-bio.NC↗

arXiv2013

Afferent specificity, feature specific connectivity influence orientation selectivity: A computational study in mouse primary visual cortex

Primary visual cortex (V1) provides crucial insights into the selectivity and emergence of specific output features such as orientation tuning. Tuning and selectivity of cortical neurons in mouse visual cortex is not equivocally resolved so far. While many in-vivo experimental studies found inhibitory neurons of all subtypes to be broadly tuned for orientation other studies report inhibitory neurons that are as sharply tuned as excitatory neurons. These diverging findings about the selectivity of excitatory and inhibitory cortical neurons prompted us to ask the following questions: (1) How different or similar is the cortical computation with that in previously described species that relies on map? (2) What is the network mechanism underlying the sharpening of orientation selectivity in the mouse primary visual cortex? Here, we investigate the above questions in a computational framework with a recurrent network composed of Hodgkin-Huxley (HH) point neurons. Our cortical network with random connectivity alone could not account for all the experimental observations, which led us to hypothesize, (a) Orientation dependent connectivity (b) Feedforward afferent specificity to understand orientation selectivity of V1 neurons in mouse. Using population (orientation selectivity index) OSI as a measure of neuronal selectivity to stimulus orientation we test each hypothesis separately and in combination against experimental data. Based on our analysis of orientation selectivity (OS) data we find a good fit of network parameters in a model based on afferent specificity and connectivity that scales with feature similarity. We conclude that this particular model class best supports data sets of orientation selectivity of excitatory and inhibitory neurons in layer 2/3 of primary visual cortex of mouse.

q-bio.NC↗