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Naji Khosravan

Publications and source records attributed to Naji Khosravan.

22 records · Page 2Linked to original sources

S4ND: Single-Shot Single-Scale Lung Nodule Detection

The state of the art lung nodule detection studies rely on computationally expensive multi-stage frameworks to detect nodules from CT scans. To address this computational challenge and provide better performance, in this paper we propose S4ND, a new deep learning based method for lung nodule detection. Our approach uses a single feed forward pass of a single network for detection and provides better performance when compared to the current literature. The whole detection pipeline is designed as a single $3D$ Convolutional Neural Network (CNN) with dense connections, trained in an end-to-end manner. S4ND does not require any further post-processing or user guidance to refine detection results. Experimentally, we compared our network with the current state-of-the-art object detection network (SSD) in computer vision as well as the state-of-the-art published method for lung nodule detection (3D DCNN). We used publically available $888$ CT scans from LUNA challenge dataset and showed that the proposed method outperforms the current literature both in terms of efficiency and accuracy by achieving an average FROC-score of $0.897$. We also provide an in-depth analysis of our proposed network to shed light on the unclear paradigms of tiny object detection.

cs.CV↗

Semi-supervised multi-task learning for lung cancer diagnosis

Early detection of lung nodules is of great importance in lung cancer screening. Existing research recognizes the critical role played by CAD systems in early detection and diagnosis of lung nodules. However, many CAD systems, which are used as cancer detection tools, produce a lot of false positives (FP) and require a further FP reduction step. Furthermore, guidelines for early diagnosis and treatment of lung cancer are consist of different shape and volume measurements of abnormalities. Segmentation is at the heart of our understanding of nodules morphology making it a major area of interest within the field of computer aided diagnosis systems. This study set out to test the hypothesis that joint learning of false positive (FP) nodule reduction and nodule segmentation can improve the computer aided diagnosis (CAD) systems' performance on both tasks. To support this hypothesis we propose a 3D deep multi-task CNN to tackle these two problems jointly. We tested our system on LUNA16 dataset and achieved an average dice similarity coefficient (DSC) of 91% as segmentation accuracy and a score of nearly 92% for FP reduction. As a proof of our hypothesis, we showed improvements of segmentation and FP reduction tasks over two baselines. Our results support that joint training of these two tasks through a multi-task learning approach improves system performance on both. We also showed that a semi-supervised approach can be used to overcome the limitation of lack of labeled data for the 3D segmentation task.

cs.CV↗

A Collaborative Computer Aided Diagnosis (C-CAD) System with Eye-Tracking, Sparse Attentional Model, and Deep Learning

There are at least two categories of errors in radiology screening that can lead to suboptimal diagnostic decisions and interventions:(i)human fallibility and (ii)complexity of visual search. Computer aided diagnostic (CAD) tools are developed to help radiologists to compensate for some of these errors. However, despite their significant improvements over conventional screening strategies, most CAD systems do not go beyond their use as second opinion tools due to producing a high number of false positives, which human interpreters need to correct. In parallel with efforts in computerized analysis of radiology scans, several researchers have examined behaviors of radiologists while screening medical images to better understand how and why they miss tumors, how they interact with the information in an image, and how they search for unknown pathology in the images. Eye-tracking tools have been instrumental in exploring answers to these fundamental questions. In this paper, we aim to develop a paradigm shift CAD system, called collaborative CAD (C-CAD), that unifies both of the above mentioned research lines: CAD and eye-tracking. We design an eye-tracking interface providing radiologists with a real radiology reading room experience. Then, we propose a novel algorithm that unifies eye-tracking data and a CAD system. Specifically, we present a new graph based clustering and sparsification algorithm to transform eye-tracking data (gaze) into a signal model to interpret gaze patterns quantitatively and qualitatively. The proposed C-CAD collaborates with radiologists via eye-tracking technology and helps them to improve diagnostic decisions. The C-CAD learns radiologists' search efficiency by processing their gaze patterns. To do this, the C-CAD uses a deep learning algorithm in a newly designed multi-task learning platform to segment and diagnose cancers simultaneously.

cs.CV↗

Gaze2Segment: A Pilot Study for Integrating Eye-Tracking Technology into Medical Image Segmentation

This study introduced a novel system, called Gaze2Segment, integrating biological and computer vision techniques to support radiologists' reading experience with an automatic image segmentation task. During diagnostic assessment of lung CT scans, the radiologists' gaze information were used to create a visual attention map. This map was then combined with a computer-derived saliency map, extracted from the gray-scale CT images. The visual attention map was used as an input for indicating roughly the location of a object of interest. With computer-derived saliency information, on the other hand, we aimed at finding foreground and background cues for the object of interest. At the final step, these cues were used to initiate a seed-based delineation process. Segmentation accuracy of the proposed Gaze2Segment was found to be 86% with dice similarity coefficient and 1.45 mm with Hausdorff distance. To the best of our knowledge, Gaze2Segment is the first true integration of eye-tracking technology into a medical image segmentation task without the need for any further user-interaction.

cs.CV↗