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Nan Bi

Publications and source records attributed to Nan Bi.

8 recordsLinked to original sources

ReMiX-MAE: Learning Missing-Channel Cross-Modal Representations from RGB-Only Clinical Facial Videos for Sympathetic-Mediated Pain Assessment

Automated pain assessment in real clinics is limited by scarce clinically grounded facial video data with weak labels (often sequence-level self-report) and by the fact that pain cues can be subtle or near-neutral in RGB, while thermal and depth signals are informative yet impractical to deploy routinely. To address these challenges, we propose ReMiX-MAE (Reconstructing Missing Channel Cross-Modal Masked Autoencoder), a self-supervised multimodal masked pretraining framework that learns transferable facial representations from synchronized RGB, thermal, and depth videos and explicitly trains robustness to missing modalities, enabling RGB-only deployment. To fill the gap of clinically grounded facial pain data with video-level self-report and longitudinal treatment trajectories, we collect the Sympathetic Mediated Pain (SMP) dataset with paired pre- and post-recordings across multiple visits. Under RGB-only deployment, we evaluate ReMiX-MAE using both direct feature extraction and pseudo-multimodal features decoded from RGB. ReMiX-MAE consistently outperforms an RGB-only masked autoencoder baseline on SMP, with pseudo-multimodal features providing additional gains in the challenging five-class setting. Across external datasets, ReMiX-MAE further shows more robust and label-efficient transfer than RGB-only baselines, highlighting its advantage in data-limited clinical settings.

cs.CV

Inter-Stance: A Dyadic Multimodal Corpus for Conversational Stance Analysis

Social interactions dominate our perceptions of the world and shape our daily behavior by attaching social meaning to acts as simple and spontaneous as gestures, facial expressions, voice, and speech. People mimic and otherwise respond to each other's postures, facial expressions, mannerisms, and other verbal and nonverbal behavior, and form appraisals or evaluations in the process. Yet, no publicly-available dataset includes multimodal recordings and self-report measures of multiple persons in social interaction. Dyadic recordings and annotation are lacking. We present a new data corpus of multimodal dyadic interaction (45 dyads, 90 persons) that includes synchronized multi-modality behavior (2D face video, 3D face geometry, thermal spectrum dynamics, voice and speech behavior, physiology (PPG, EDA, heart-rate, blood pressure, and respiration), and self-reported affect of all participants in a communicative interaction scenario. Two types of dyads are included: persons with shared past history and strangers. Annotations include social signals, agreement, disagreement, and neutral stance. With a potent emotion induction, these multimodal data will enable novel modeling of multimodal interpersonal behavior. We present extensive experiments to evaluate multimodal dyadic communication of dyads with and without interpersonal history, and their affect. This new database will make multimodal modeling of social interaction never possible before. The dataset includes 20TB of multimodal data to share with the research community.

cs.CV

A Transformer-based Deep Learning Algorithm to Auto-record Undocumented Clinical One-Lung Ventilation Events

As a team studying the predictors of complications after lung surgery, we have encountered high missingness of data on one-lung ventilation (OLV) start and end times due to high clinical workload and cognitive overload during surgery. Such missing data limit the precision and clinical applicability of our findings. We hypothesized that available intraoperative mechanical ventilation and physiological time-series data combined with other clinical events could be used to accurately predict missing start and end times of OLV. Such a predictive model can recover existing miss-documented records and relieves the documentation burden by deploying it in clinical settings. To this end, we develop a deep learning model to predict the occurrence and timing of OLV based on routinely collected intraoperative data. Our approach combines the variables' spatial and frequency domain features, using Transformer encoders to model the temporal evolution and convolutional neural network to abstract frequency-of-interest from wavelet spectrum images. The performance of the proposed method is evaluated on a benchmark dataset curated from Massachusetts General Hospital (MGH) and Brigham and Women's Hospital (BWH). Experiments show our approach outperforms baseline methods significantly and produces a satisfactory accuracy for clinical use.

eess.SP

Inferring Treatment Effects After Testing Instrument Strength in Linear Models

A common practice in IV studies is to check for instrument strength, i.e. its association to the treatment, with an F-test from regression. If the F-statistic is above some threshold, usually 10, the instrument is deemed to satisfy one of the three core IV assumptions and used to test for the treatment effect. However, in many cases, the inference on the treatment effect does not take into account the strength test done a priori. In this paper, we show that not accounting for this pretest can severely distort the distribution of the test statistic and propose a method to correct this distortion, producing valid inference. A key insight in our method is to frame the F-test as a randomized convex optimization problem and to leverage recent methods in selective inference. We prove that our method provides conditional and marginal Type I error control. We also extend our method to weak instrument settings. We conclude with a reanalysis of studies concerning the effect of education on earning where we show that not accounting for pre-testing can dramatically alter the original conclusion about education's effects.

stat.ME

Inference After Selecting Plausibly Valid Instruments with Application to Mendelian Randomization

Mendelian randomization (MR) is a popular method in genetic epidemiology to estimate the effect of an exposure on an outcome by using genetic instruments. These instruments are often selected from a combination of prior knowledge from genome wide association studies (GWAS) and data-driven instrument selection procedures or tests. Unfortunately, when testing for the exposure effect, the instrument selection process done a priori is not accounted for. This paper studies and highlights the bias resulting from not accounting for the instrument selection process by focusing on a recent data-driven instrument selection procedure, sisVIVE, as an example. We introduce a conditional inference approach that conditions on the instrument selection done a priori and leverage recent advances in selective inference to derive conditional null distributions of popular test statistics for the exposure effect in MR. The null distributions can be characterized with individual-level or summary-level data in MR. We show that our conditional confidence intervals derived from conditional null distributions attain the desired nominal level while typical confidence intervals computed in MR do not. We conclude by reanalyzing the effect of BMI on diastolic blood pressure using summary-level data from the UKBiobank that accounts for instrument selection.

stat.ME

Inferactive data analysis

We describe inferactive data analysis, so-named to denote an interactive approach to data analysis with an emphasis on inference after data analysis. Our approach is a compromise between Tukey's exploratory (roughly speaking "model free") and confirmatory data analysis (roughly speaking classical and "model based"), also allowing for Bayesian data analysis. We view this approach as close in spirit to current practice of applied statisticians and data scientists while allowing frequentist guarantees for results to be reported in the scientific literature, or Bayesian results where the data scientist may choose the statistical model (and hence the prior) after some initial exploratory analysis. While this approach to data analysis does not cover every scenario, and every possible algorithm data scientists may use, we see this as a useful step in concrete providing tools (with frequentist statistical guarantees) for current data scientists. The basis of inference we use is selective inference [Lee et al., 2016, Fithian et al., 2014], in particular its randomized form [Tian and Taylor, 2015a]. The randomized framework, besides providing additional power and shorter confidence intervals, also provides explicit forms for relevant reference distributions (up to normalization) through the {\em selective sampler} of Tian et al. [2016]. The reference distributions are constructed from a particular conditional distribution formed from what we call a DAG-DAG -- a Data Analysis Generative DAG. As sampling conditional distributions in DAGs is generally complex, the selective sampler is crucial to any practical implementation of inferactive data analysis. Our principal goal is in reviewing the recent developments in selective inference as well as describing the general philosophy of selective inference.

math.ST

Selective sampling after solving a convex problem

We consider the problem of selective inference after solving a (randomized) convex statistical learning program in the form of a penalized or constrained loss function. Our first main result is a change-of-measure formula that describes many conditional sampling problems of interest in selective inference. Our approach is model-agnostic in the sense that users may provide their own statistical model for inference, we simply provide the modification of each distribution in the model after the selection. Our second main result describes the geometric structure in the Jacobian appearing in the change of measure, drawing connections to curvature measures appearing in Weyl-Steiner volume-of-tubes formulae. This Jacobian is necessary for problems in which the convex penalty is not polyhedral, with the prototypical example being group LASSO or the nuclear norm. We derive explicit formulae for the Jacobian of the group LASSO. To illustrate the generality of our method, we consider many examples throughout, varying both the penalty or constraint in the statistical learning problem as well as the loss function, also considering selective inference after solving multiple statistical learning programs. Penalties considered include LASSO, forward stepwise, stagewise algorithms, marginal screening and generalized LASSO. Loss functions considered include squared-error, logistic, and log-det for covariance matrix estimation. Having described the appropriate distribution we wish to sample from through our first two results, we outline a framework for sampling using a projected Langevin sampler in the (commonly occuring) case that the distribution is log-concave.

math.ST

MAGIC: a general, powerful and tractable method for selective inference

Selective inference is a recent research topic that tries to perform valid inference after using the data to select a reasonable statistical model. We propose MAGIC, a new method for selective inference that is general, powerful and tractable. MAGIC is a method for selective inference after solving a convex optimization problem with smooth loss and $\ell_1$ penalty. Randomization is incorporated into the optimization problem to boost statistical power. Through reparametrization, MAGIC reduces the problem into a sampling problem with simple constraints. MAGIC applies to many $\ell_1$ penalized optimization problem including the Lasso, logistic Lasso and neighborhood selection in graphical models, all of which we consider in this paper.

math.ST