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Naoya Fujiwara

Publications and source records attributed to Naoya Fujiwara.

16 recordsLinked to original sources

Coevolution of epidemic dynamics and network topology driven by disease fatality and waning immunity

Epidemics on complex networks have been shown to exhibit dynamics that are strongly influenced by the topology of the network. However, it remains unclear how the topology of the network is influenced by epidemic properties, such as waning immunity and disease fatality, coupled with demographic changes. To explore the interplay between epidemic dynamics and network topology, we develop an agent-based model of a fatal infectious disease with an imperfect immunity on an initially scale-free network that evolves via demographic and epidemic-induced changes. We show that this model undergoes an epidemic transition between a phase in which the disease eventually dies out and a phase in which it becomes endemic. Moreover, the network may lose its scale-free property as a result of the epidemic spreading, giving rise to a topological transition from a power-law to a non-power-law degree distribution. We validate our findings using heterogeneous mean-field approximations of the agent-based model. These results highlight the importance of accounting for network evolution in epidemic models and advance our understanding of coevolving dynamical systems, in which disease dynamics and network topology continuously shape one another.

physics.soc-ph

Potential Landscapes Reveal Spatiotemporal Structure in Urban Mobility: Hodge Decomposition and Principal Component Analysis of Tokyo Before and During COVID-19

Understanding human mobility is vital to solving societal challenges, such as epidemic control and urban transportation optimization. Recent advancements in data collection now enable the exploration of dynamic mobility patterns in human flow. However, the vast volume and complexity of mobility data make it difficult to interpret spatiotemporal patterns directly, necessitating effective information reduction. The core challenge is to balance data simplification with information preservation: methods must retain location-specific information about human flows from origins to destinations while reducing the data to a comprehensible level. This study proposes a two-step dimensionality reduction framework: First, combinatorial Hodge theory is applied to the given origin--destination (OD) matrices with timestamps to construct a set of potential landscapes of human flow, preserving imbalanced trip information between locations. Second, principal component analysis (PCA) expresses the time series of potential landscapes as a linear combination of a few static spatial components, with their coefficients representing temporal variations. The framework systematically decouples the spatial and temporal components of the given data. By implementing this two-step reduction method, we reveal large weight variations during a pandemic, characterized by an overall decline in mobility and stark contrasts between weekdays and holidays. These findings demonstrate the effectiveness of our framework in uncovering complex mobility patterns and its potential to inform urban planning and public health interventions.

cs.SI

Geospatial analysis of toponyms in geotagged social media posts

Place names, or toponyms, play an integral role in human representation and communication of geographic space. In particular, how people relate each toponym with particular locations in geographic space should be indicative of their spatial perception. Here, we make use of an extensive dataset of georeferenced social media posts, retrieved from Twitter, to perform a statistical analysis of the geographic distribution of toponyms and uncover the relationship between toponyms and geographic space. We show that the occurrence of toponyms is characterized by spatial inhomogeneity, giving rise to patterns that are distinct from the distribution of common nouns. Using simple models, we quantify the spatial specificity of toponym distributions and identify their core-periphery structures. In particular, we find that toponyms are used with a probability that decays as a power law with distance from the geographic center of their occurrence. Our findings highlight the potential of social media data to explore linguistic patterns in geographic space, paving the way for comprehensive analyses of human spatial representations.

physics.soc-ph

Directional intermodular coupling enriches functional complexity in biological neuronal networks

Hierarchically modular organization is a canonical network topology that is evolutionarily conserved in the nervous systems of animals. Within the network, neurons form directional connections defined by the growth of their axonal terminals. However, this topology is dissimilar to the network formed by dissociated neurons in culture because they form randomly connected networks on homogeneous substrates. In this study, we fabricated microfluidic devices to reconstitute hierarchically modular neuronal networks in culture (in vitro) and investigated how non-random structures, such as directional connectivity between modules, affect global network dynamics. Embedding directional connections in a pseudo-feedforward manner suppressed excessive synchrony in cultured neuronal networks and enhanced the integration-segregation balance. Modeling the behavior of biological neuronal networks using spiking neural networks (SNNs) further revealed that modularity and directionality cooperate to shape such network dynamics. Finally, we demonstrate that for a given network topology, the statistics of network dynamics, such as global network activation, correlation coefficient, and functional complexity, can be analytically predicted based on eigendecomposition of the transition matrix in the state-transition model. Hence, the integration of bioengineering and cell culture technologies enables us not only to reconstitute complex network circuitry in the nervous system but also to understand the structure-function relationships in biological neuronal networks by bridging theoretical modeling with in vitro experiments.

q-bio.NC

Identifying sinks and sources of human flows: A new approach to characterizing urban structures

Human flow data are rich behavioral data relevant to people's decision-making regarding where to live, work, go shopping, etc., and provide vital information for identifying city centers. However, it is not as easy to understand massive relational data, and datasets have often been reduced merely to the statistics of trip counts at destinations, discarding relational information from origin to destination. In this study, we propose an alternative center identification method based on human mobility data. This method extracts the scalar potential field of human trips based on combinatorial Hodge theory. It detects not only statistically significant attractive locations as the sinks of human trips but also significant origins as the sources of trips. As a case study, we identify the sinks and sources of commuting and shopping trips in the Tokyo metropolitan area. This aim-specific analysis leads to a combinatorial classification of city centers based on the distinct aspects of human mobility. The proposed method can be applied to other mobility datasets with relevant properties and helps us examine the complex spatial structures in contemporary metropolitan areas from the multiple perspectives of human mobility.

physics.soc-ph

Influence of trip distance and population density on intra-city mobility patterns in Tokyo during COVID-19 pandemic

This study investigates the influence of infection cases of COVID-19 and two non-compulsory lockdowns on human mobility within the Tokyo metropolitan area. Using the data of hourly staying population in each 500m$\times$500m cell and their city-level residency, we show that long-distance trips or trips to crowded places decrease significantly when infection cases increase. The same result holds for the two lockdowns, although the second lockdown was less effective. Hence, Japanese non-compulsory lockdowns influence mobility in a similar way to the increase in infection cases. This means that they are accepted as alarm triggers for people who are at risk of contracting COVID-19.

econ.GN

Urban spatial structures from human flow by Hodge-Kodaira decomposition

Human flow in cities indicates social activity and can reveal urban spatial structures based on human behaviours for relevant applications. Scalar potential is a mathematical concept, and if successfully introduced, it can provide an intuitive perspective of human flow. However, the definition of such a potential to the origin-destination flow matrix and determination of its plausibility remain unsolved. Here, we apply Hodge-Kodaira decomposition, in which a matrix is uniquely decomposed into a potential-driven (gradient) flow and a curl flow. We depict the potential landscapes in cities due to commuting flow and reveal how the landscapes have been changed or unchanged by years or transport methods. We then determine how well the commuting flow is described by the potential, by evaluating the percentage of the gradient component for metropolitan areas in the USA and show that the gradient component is almost 100\% in several areas; in other areas, however, the curl component is dominant, indicating the importance of circular flow along triangles of places. The potential landscape provides an easy-to-use visualisation tool to show the attractive places of human flow and will aid in various applications in commerce, urban design, and epidemic spreading.

physics.soc-ph

Analytical estimation of maximum fraction of infected individuals with one-shot non-pharmaceutical intervention in a hybrid epidemic model

Facing a global epidemic of new infectious diseases such as COVID-19, non-pharmaceutical interventions (NPIs), which reduce transmission rates without medical actions, are being implemented around the world to mitigate spreads. One of the problems in assessing the effects of NPIs is that different NPIs have been implemented at different times based on the situation of each country; therefore, few assumptions can be shared about how the introduction of policies affects the patient population. Mathematical models can contribute to further understanding these phenomena by obtaining analytical solutions as well as numerical simulations. In this study, an NPI was introduced into the SIR model for a conceptual study of infectious diseases under the condition that the transmission rate was reduced to a fixed value only once within a finite time duration, and its effect was analyzed numerically and theoretically. It was analytically shown that the maximum fraction of infected individuals and the final size could be larger if the intervention starts too early. The analytical results also suggested that more individuals may be infected at the peak of the second wave with a stronger intervention. This study provides quantitative relationship between the strength of a one-shot intervention and the reduction in the number of patients with no approximation. This suggests the importance of the strength and time of NPIs, although detailed studies are necessary for the implementation of NPIs in complicated real-world environments as the model used in this study is based on various simplifications.

q-bio.PE

Non-Compulsory Measures Sufficiently Reduced Human Mobility in Tokyo during the COVID-19 Epidemic

While large scale mobility data has become a popular tool to monitor the mobility patterns during the COVID-19 pandemic, the impacts of non-compulsory measures in Tokyo, Japan on human mobility patterns has been under-studied. Here, we analyze the temporal changes in human mobility behavior, social contact rates, and their correlations with the transmissibility of COVID-19, using mobility data collected from more than 200K anonymized mobile phone users in Tokyo. The analysis concludes that by April 15th (1 week into state of emergency), human mobility behavior decreased by around 50%, resulting in a 70% reduction of social contacts in Tokyo, showing the effectiveness of non-compulsory measures. Furthermore, the reduction in data-driven human mobility metrics showed correlation with the decrease in estimated effective reproduction number of COVID-19 in Tokyo. Such empirical insights could inform policy makers on deciding sufficient levels of mobility reduction to contain the disease.

physics.soc-ph

Chaos may enhance expressivity in cerebellar granular layer

Recent evidence suggests that Golgi cells in the cerebellar granular layer are densely connected to each other with massive gap junctions. Here, we propose that the massive gap junctions between the Golgi cells contribute to the representational complexity of the granular layer of the cerebellum by inducing chaotic dynamics. We construct a model of cerebellar granular layer with diffusion coupling through gap junctions between the Golgi cells, and evaluate the representational capability of the network with the reservoir computing framework. First, we show that the chaotic dynamics induced by diffusion coupling results in complex output patterns containing a wide range of frequency components. Second, the long non-recursive time series of the reservoir represents the passage of time from an external input. These properties of the reservoir enable mapping different spatial inputs into different temporal patterns.

q-bio.NC

Universality of population recovery patterns after disasters

Despite the rising importance of enhancing community resilience to disasters, our understanding on how communities recover from catastrophic events is limited. Here we study the population recovery dynamics of disaster affected regions by observing the movements of over 2.5 million mobile phone users across three countries before, during and after five major disasters. We find that, although the regions affected by the five disasters have significant differences in socio-economic characteristics, we observe a universal recovery pattern where displaced populations return in an exponential manner after all disasters. Moreover, the heterogeneity in initial and long-term displacement rates across communities across the three countries were explained by a set of key universal factors including the community's median income level, population size, housing damage rate, and the connectedness to other cities. These universal properties of recovery dynamics extracted from large scale evidence could impact efforts on urban resilience and sustainability across various disciplines.

physics.soc-ph

A perturbative approach to Lagrangian flow networks

Complex network approaches have been successfully applied for studying transport processes in complex systems ranging from road, railway or airline infrastructure over industrial manufacturing to fluid dynamics. Here, we utilize a generic framework for describing the dynamics of geophysical flows such as ocean currents or atmospheric wind fields in terms of Lagrangian flow networks. In this approach, information on the passive advection of particles is transformed into a Markov chain based on transition probabilities of particles between the volume elements of a given partition of space for a fixed time step. We employ perturbation-theoretic methods to investigate the effects of modifications of transport processes in the underlying flow for three different problem classes: efficient absorption (corresponding to particle trapping or leaking), constant input of particles (with additional source terms modeling, e.g., localized contamination), and shifts of the steady state under probability mass conservation (as arising if the background flow is perturbed itself). Our results demonstrate that in all three cases, changes to the steady state solution can be analytically expressed in terms of the eigensystem of the unperturbed flow and the perturbation itself. These results are potentially relevant for developing more efficient strategies for coping with contaminations of fluid or gaseous media such as ocean and atmosphere by oil spills, radioactive substances, non-reactive chemicals or volcanic aerosols.

physics.flu-dyn

Contribution of hidden modes to nonlinear epidemic dynamics in urban human proximity networks

Recently developed techniques to acquire high-quality human mobility data allow large-scale simulations of the spread of infectious diseases with high spatial and temporal resolution.Analysis of such data has revealed the oversimplification of existing theoretical frameworks to infer the final epidemic size or influential nodes from the network topology. Here we propose a spectral decomposition-based framework for the quantitative analysis of epidemic processes on realistic networks of human proximity derived from urban mobility data. Common wisdom suggests that modes with larger eigenvalues contribute more to the epidemic dynamics. However, we show that hidden dominant structures, namely modes with smaller eigenvalues but a greater contribution to the epidemic dynamics, exist in the proximity network. This framework provides a basic understanding of the relationship between urban human motion and epidemic dynamics, and will contribute to strategic mitigation policy decisions.

physics.soc-ph

Smoothing effect for spatially distributed renewable resources and its impact on power grid robustness

In this paper, we show that spatial correlation of renewable energy outputs greatly influences the robustness of power grids. First, we propose a new index for the spatial correlation among renewable energy outputs. We find that the spatial correlation of renewable energy outputs in a short time-scale is as weak as that caused by independent random variables and that in a long time-scale is as strong as that under perfect synchronization. Then, by employing the topology of the power grid in eastern Japan, we analyze the robustness of the power grid with spatial correlation of renewable energy outputs. The analysis is performed by using a realistic differential-algebraic equations model and the result shows that the spatial correlation of the energy resources strongly degrades the robustness of the power grid. Our result suggests that the spatial correlation of the renewable energy outputs should be taken into account when estimating the stability of power grids.

physics.soc-ph

Towards dynamical network biomarkers in neuromodulation of episodic migraine

Computational methods have complemented experimental and clinical neursciences and led to improvements in our understanding of the nervous systems in health and disease. In parallel, neuromodulation in form of electric and magnetic stimulation is gaining increasing acceptance in chronic and intractable diseases. In this paper, we firstly explore the relevant state of the art in fusion of both developments towards translational computational neuroscience. Then, we propose a strategy to employ the new theoretical concept of dynamical network biomarkers (DNB) in episodic manifestations of chronic disorders. In particular, as a first example, we introduce the use of computational models in migraine and illustrate on the basis of this example the potential of DNB as early-warning signals for neuromodulation in episodic migraine.

q-bio.NC

Synchronization in networks of mobile oscillators

We present a model of synchronization in networks of autonomous agents where the topology changes due to agents motion. We introduce two time scales, one for the topological change and another one for local synchronization. If the former scale is much shorter, an approximation that averages out the effect of motion is available. Here we show, however, that the time required for synchronization achievement increases with respect to that approximation in the opposite case. We find that this effect is more important close to the continuum percolation transition point. The simulation results are confirmed by means of spectral analysis of the time dependent Laplacian matrix. Our results show that the trade-off between these two time scales, which have opposite effects on synchronization, should be taken into account for the design of mobile device networks.

nlin.AO