arXiv subjects

Nassir Navab

Publications and source records attributed to Nassir Navab.

At least 19 recordsLinked to original sources

arXiv2026

Multimodal Shared Latent Representation of Narration, Microscope and iOCT Images for Phase Recognition in Vitreoretinal Surgery

Surgical phase recognition is key to context-aware computer-assisted feedback in vitreoretinal procedures, yet the scarcity of synchronized multimodal intraoperative data, particularly microscope views and intraoperative OCT, limits approaches that aim to replicate the multimodal integration surgeons perform naturally. Surgical narration, by contrast, is abundantly available online and offers rich semantic supervision. Prior work has mainly explored pairwise contrastive learning (e.g., intraoperative OCT-microscope or microscope-narration), leaving the joint modeling of all three modalities largely unexplored. We introduce a framework that uses microscope views as a shared anchor to bridge surgical narrations and intraoperative OCT (iOCT) without requiring a fully synchronized tri-modal dataset, leveraging real microscope-narration videos and a synthetic dataset of synchronized microscope video and tool-aligned iOCT pairs. Contrastive alignment transfers structural priors from the synthetic domain to real videos lacking iOCT, and a dual-head MS-TCN++ integrates the resulting embeddings for joint macro- and micro-phase prediction. Evaluated on real vitreoretinal surgeries, our framework improves macro-phase recognition over a zero-shot baseline (mean F1 0.38 to 0.53) and provides an exploratory route to estimating fine-grained instrument-tissue measurements that are not directly observable in real microscope video alone; these micro-phase estimates are validated quantitatively on synthetic data and shown only qualitatively on real surgery. To our knowledge, this is the first work to unify microscope view, iOCT B-scans, and surgical narrations in a shared latent space for surgical phase recognition.

cs.CV↗

arXiv2026

ZODIAC: Zero-shot Octree-based Diffusion for Anatomical Completion

Recovering the full 3D spine anatomy from intraoperative ultrasound is an ill-posed inverse problem, as the complete structure must be inferred from incomplete and noisy observations. Acoustic occlusions and limited field of view create large unobserved regions, while view-dependent artifacts lead to variability in expert annotations of the visible anatomy. Current supervised ultrasound shape completion methods rely on synthetically generated incomplete-complete paired data to learn conditional mappings under a predefined distribution of simulated occlusions. However, real intraoperative occlusions do not necessarily follow this distribution, which can limit generalization to patient data. As a result, accurate and robust completion from noisy partial observations remains an unsolved problem. We propose a zero-shot shape completion framework that reconstructs the entire lumbar spine from partial ultrasound observations without relying on simulated training data. To accommodate unseen and irregular patterns of missing structures, we introduce blended completion, a mechanism that integrates the learned anatomical prior with incoming partial geometry at inference time. The method learns a generative diffusion prior over full anatomical shapes represented in an adaptive octree structure, enabling efficient modeling of the complete spine in a single forward pass. Validation on phantom and volunteer data shows that decoupling completion from a predefined corruption distribution improves generalisation under real occlusions, outperforming a fully supervised variant by 22% on HD95 completion error. Code and data are available at https://github.com/miruna20/ZODIAC.

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arXiv2026

SOS! : A Streamlined Object-Conditional Transformer for Model-free Segmentation

Foundation segmentation models excel at generating high-quality, class-agnostic masks, but they struggle to associate these proposals with specific target objects. This semantic gap severely hinders their deployment in downstream applications like robotic manipulation, which demand precise unseen objects segmentation. Existing approaches attempt to resolve this by relying on exhaustive 3D object model priors, inherently introducing prohibitive computational overhead and complex, multi-stage pipelines. To address these limitations, we propose SOS (Streamlined Object-conditional Transformer for model-free Segmentation). SOS completely eliminates the reliance on 3D models, requiring only a single reference image per target object. Central to our framework is a novel Object-Conditional Transformer that learns identity-anchored queries, unifying mask generation and target identification into a single feed-forward pass. This streamlined design drastically improves both structural and computational efficiency. Extensive evaluations across multiple benchmarks demonstrate that SOS establishes a new state-of-the-art for model-free unseen objects segmentation, delivering accurate and high-efficiency performance. The project page and code are available at https://sos-seg.github.io/.

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arXiv2026

Modular Robotic Catheters for Endovascular Aneurysm Repair

Fenestrated/Branched endovascular aneurysm repair (FEVAR/BEVAR) require surgeons to navigate catheters and guidewires into various branches of the abdominal aorta, before deploying stent grafts to alleviate pressure on the aneurysm. Previous clinical studies suggests that surgeons continue to struggle with vessel access using standard commercial instruments, prolonging the procedural time and inducing further complications. In this work, we present two contributions to solving this problem: 1) A bespoke 2-segment steerable catheter, consisting of 4 degrees of freedom to enhance dexterity. 2) An expandable, modular tendon-driven actuation platform that can accommodate for the redundancies introduced in our system. To fabricate the catheter, we capitalized on thermal fiber drawing, a technique that creates high-aspect ratio devices at scale, and processed the catheter with laser micro-machining to soften its tip. We evaluated the system using simulations, where we investigated the catheter's bending stiffness, then its steerability with in-vitro experiments in vascular phantoms. This handheld, robotic steerable catheter system has the potential to shorten the length of future endovascular surgeries, and give clinicians the tools to resolve challenging clinical cases.

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arXiv2026

Policy-Driven CT-Agent: Modeling Phase-Aware Diagnostic Control for Clinically Consistent CT Reasoning

Computed Tomography (CT) diagnosis often relies on dynamic selection of imaging phases, such as non-contrast, arterial, or venous phases, based on preliminary findings, clinical suspicion, and diagnostic guidelines. This phase-wise decision process is critical for reducing unnecessary radiation exposure while supporting timely staging and treatment planning. However, phase-selection protocols can vary across hospitals, regions, and guidelines, while most existing CT-based AI methods assume that all phases are available and focus on static tasks under a fixed imaging phase, failing to model whether additional phases are required. This limitation stems from heterogeneous multi-phase representations, the need for knowledge-guided phase control beyond visual cues, and the lack of supervision for phase-sufficiency decisions in existing datasets. To address these challenges, we propose Policy-Driven CT-Agent (PD-CTAgent) for clinically consistent CT phase selection and diagnostic reasoning. PD-CTAgent introduces a Clinical Structure Abstraction Module (CSAM) to harmonize heterogeneous CT phases into a unified, phase-aware evidence representation. Based on this representation, a Knowledge-Guided Diagnostic Control Model (KDCM) evaluates phase sufficiency and iteratively requests additional phases when necessary. The policy-driven agent design further allows PD-CTAgent to flexibly follow different institutional, regional, or guideline-specific diagnostic protocols. Together, PD-CTAgent bridges static CT analysis and real-world clinical workflows. Experiments on two public datasets, LIDC and MCT-LTDiag, and one private dataset demonstrate its effectiveness and clinical consistency. Code will be made public upon acceptance.

cs.LG↗

arXiv2026

MAC-XA: Multi-view Anatomy-Correspondence Fusion for Coronary Stenosis Reporting from X-ray Angiography

Multi-view reasoning in coronary X-ray angiography is inherently a cross-projection geometric problem, yet automated report generation in this setting remains largely unexplored. The 3D vascular topology leads to projection-dependent branch overlap and foreshortening, rendering single-view modeling fundamentally incomplete and unstable for lesion localization and stenosis grading. Although multi-view fusion appears promising, learning anatomically consistent fusion from real angiograms is impeded by a critical limitation: cross-view alignment is unobservable and cannot be explicitly supervised. Consequently, conventional fusion relies on implicit correlations rather than verified anatomical correspondence. We address this by reformulating multi-view stenosis reporting as an alignment-constrained aggregation problem. A controllable synthetic angiography generation strategy is introduced to expose geometry-derived patch-level correspondence supervision unavailable in real data. An anatomy-correspondence module learns cross-view correspondence matrices that explicitly align auxiliary features within the main-view coordinate space prior to fusion, thereby constraining evidence aggregation to anatomically consistent regions. Experiments on synthetic data and zero-shot transfer to real angiograms show that this alignment-constrained design improves correspondence consistency and structured stenosis reporting compared to single-view modeling and conventional multi-view fusion methods. The code will be publicly available upon publication.

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arXiv2026

Paired Uterine Whole-Slide Images and Pathology Reports for Multimodal Computational Pathology

Uterine diseases represent an important category of gynecologic pathology and require accurate histopathological assessment for diagnosis and treatment planning. Whole-slide images (WSI) have enabled the digital transformation of pathology workflows and provided new opportunities for artificial intelligence (AI) in computational pathology. In particular, multimodal models that jointly analyze histopathology images and pathology reports have shown promising potential for automated pathology report generation and AI-assisted diagnosis. However, the development of such systems remains limited by the scarcity of datasets that pair whole-slide images with clinically meaningful pathology reports. Instead, existing pathology datasets focus on patch- or slide-level annotations of a single endpoint (e.g., disease class), which do not fully capture the rich information in full clinical diagnostic workflow reports. Here, we introduce TUM-Uteria, a uterine pathology dataset comprising WSIs paired with diagnostic pathology reports at both the case and slide levels, collected from a tertiary medical center. The dataset contains 216 clinical cases, comprising 455 slide-level WSI-report pairs. The dataset underwent a structured multi-stage validation procedure involving board-certified pathologists to ensure reliable annotations. TUM-Uteria supports research in computational pathology, including whole-slide image analysis, multimodal learning, and automated pathology report generation.

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arXiv2026

HyperVLP: Enhancing Hierarchical Surgical Video-Language Pre-training in Hyperbolic Space

Surgical vision-language foundation models typically adopt educational materials, such as surgical lecture videos, to transfer surgical knowledge encoded in language into visual representations. These knowledge are multi-dimensional and hierarchical: fine-grained action cues appear in narration, mid-level key steps are summarized in subsection headings, and global procedural context, such as patient history and surgical strategy, is described in abstract texts. Prior work largely collapses these heterogeneous signals into a single flat embedding space, implicitly assuming independence across hierarchy levels. However, this is suboptimal because it ignores cross-level semantic containment, e.g., actions belong to steps, steps compose phases, weakens long-range dependency modeling. To this end, we propose a hyperbolic surgical video-language pre-training framework that explicitly preserves the hierarchical structure by mitigating structural false negatives induced by procedural context and enforcing semantic consistency between parent phases and their constituent child steps. Extensive experiments on multiple surgical benchmarks show consistent gains in zero- and few-shot phase recognition across procedures and institutions.

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arXiv2026

Towards Voxel Spacing Consistency for Medical Image Segmentation

Volumetric medical image segmentation is essential for both preoperative diagnosis and intraoperative guidance. While recent years have witnessed rapid progress in segmentation architectures, comparatively little attention is paid to the physical voxel spacing of anatomical data. Indeed, volumetric image resampling is a ubiquitous preprocessing step before segmentation, yet its interaction with downstream segmentation has not been systematically exploited. In this work, we study the correlation between image resampling and segmentation, and propose Consispace, a semantic-aware resampling framework that achieves consistent voxel spacing in the axial direction while preserving anatomical and semantic consistency. Consispace introduces an ODE-based anatomical constraint to model inter-slice dynamics with a continuous interpolator, enabling faithful reconstruction under complex anatomical transitions beyond discrete interpolation. To further couple resampling with segmentation objectives, we leverage dense features from a pretrained vision model to build intra-slice semantic correlation maps and inject class-wise semantic consistency via feature reweighting during resampling. Both intra-slice and inter-slice constraints are integrated into an implicit neural network, supporting arbitrary-scale resampling. Extensive experiments on multiple datasets demonstrate that Consispace achieves superior reconstruction quality and perceptual fidelity, produces smoother inter-slice anatomy, and improves downstream segmentation performance when used as a preprocessing step.

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arXiv2026

Re-mixing Embeddings for Patient Augmentation in Data Scarce Multiple Instance Learning

Data scarcity is a major bottleneck in medical Multiple Instance Learning (MIL), especially for rare diseases or expensive modalities. We introduce a statistically grounded patient augmentation approach that generates realistic patients directly in embedding space. Using Gaussian Mixture Models as a probabilistic clustering approach on pooled instance embeddings from all patients, our method learns disease-specific "recipes"-statistical distributions of instances across unsupervised clusters. New patients are then generated by sampling embeddings from clusters based on learned recipes. Unlike existing methods that require examples from all categories, our method can generate patients offline by re-mixing pooled embeddings. Generated patients are further selected based on uncertainty quantification to improve MIL performance. We evaluate our method across three clinically relevant scarcity scenarios: (i) cross-dataset transfer, where an entirely missing "healthy" class is generated using statistics from an external cohort; (ii) low-data regimes, where class sizes are extremely limited; and (iii) small-cohort non-image tasks, including single-cell RNA-seq and flow cytometry. Across all experiments, our method improves performance over baseline, often outperforming other bag-mixing strategies. Notably, in the missing-class scenario, a performance comparable to full-dataset training is achieved, demonstrating its potential for rare disease diagnostic and privacy-preserving patient augmentation. The code is available at https://github.com/marrlab/RECIPE

cs.LG↗

arXiv2026

P-JEPA: Procedural Video Representation Learning via Joint Embedding Predictive Architecture

The increasing maturity of embodied AI platforms has driven a growing interest in procedural video representation learning to support intelligent assistance systems for complex, multi-step tasks. Leveraging large-scale latent predictive training, video foundation models capture video dynamics, enabling downstream tasks such as activity understanding, spatiotemporal localization, and predictive control. However, procedural videos include actions with long-range dependencies that these models do not support, due to the quadratic complexity of self-attention. Distinct actions, for example, may be visually similar despite appearing at different points in the procedure, such as turning the stove on versus off. Here, we propose a backbone-agnostic approach that learns long-duration video representations by reducing the problem to a dense, frame-aligned action space and predicting pooled masked latent vectors. This approach allows our Procedural Joint Embedding Predictive Architecture (P-JEPA) to ingest videos over 30 minutes long, enabling effective long-form understanding of procedural steps. We evaluate P-JEPA using features extracted with VJEPA2.1, TSM, and I3D over the EgoExo4D, EgoProceL, and Assembly101 datasets, finding that it consistently improves linear separability, streaming inference, and temporal action segmentation performance, achieving state-of-the-art results on EgoExo4D fine-grained action classification while using an order of magnitude fewer parameters than LLM-based methods and running in real time.

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arXiv2026

Pose Anything Anywhere:Model-free Object Poses from Arbitrary References

Estimating the 6D pose of unseen objects is a fundamental yet challenging problem for open-world robotics and embodied perception. Model-based methods are accurate but depend on CAD assets or heavy onboarding, while most model-free approaches are still limited to pairwise single-anchor matching and thus fail under occlusion and large viewpoint changes with low query-reference overlap. Therefore, we present PANY, a unified model-free framework that seamlessly supports both RGB and RGB-D inputs, operates on one or sparse pose-free reference views, and generalizes effectively to novel objects. Built on a multi-view transformer geometry backbone, PANY moves beyond pairwise matching by learning view-consistent geometry and cross-view alignment cues that remain stable under wide baselines and limited overlap. When additional unposed assist views are available, PANY aggregates them via pose-graph canonical registration to increase geometric coverage and reinforce the final pose. Extensive experiments show that PANY achieves state-of-the-art performance across multiple benchmarks, substantially outperforming existing model-free methods, improving pose accuracy by +12% on YCB-V and over +20% on LM-O. Furthermore, PANY consistently performs well under both single-reference and sparse-reference settings, demonstrating strong robustness in real-world environments.

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arXiv2026

Prompting Diffusion Models for Zero-Shot Instance Segmentation

Several disruptive research directions have recently emerged in computer vision, including foundation models achieving previously unseen zero-shot performance in scene understanding, even interactively, and generative models that synthesize extremely realistic images. The latter have also been shown to be highly effective in scene understanding tasks thanks to their rich priors. However, for promptable segmentation, foundation models struggle with accurately segmenting an object's region, leading to false positives and over-segmentation. Notably, early attempts that leverage generative priors use prompts only during post-processing, yielding suboptimal segments because the process is agnostic to the user input. In this paper, we target these limitations with Prompt2Seg, a spatial conditioning framework for diffusion-based segmentation. Prompt2Seg augments a frozen diffusion segmentation model with a conditioning branch. Our approach takes spatial prompts, represented as 2D Gaussians or confidence maps, as explicit input signals, training the model to respond directly to user intent. Fine-tuned on a deliberately constrained set of object categories drawn from Hypersim and Virtual KITTI 2, Prompt2Seg generalizes zero-shot to a wide range of unseen object types and visual domains. We evaluate on seven datasets ranging from standard benchmarks to more challenging domains, including paintings, egocentric views, and X-ray data. Furthermore, we demonstrate that Prompt2Seg consistently outperforms the underlying diffusion segmentation backbone across all benchmarks. Our results suggest that the rich priors encoded in generative pretraining, combined with principled spatial conditioning, offer a compelling path toward broadly generalizing interactive segmentation without large-scale mask supervision.

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arXiv2026

Future Dynamic 3D Reconstruction: Toward 3D World Modeling with Disentangled Ego-Motion

Forecasting the evolution of dynamic environments is crucial for autonomous agents. While generative world models have achieved high photorealism in 2D video synthesis by mixing ego-motion and environmental dynamics within the image plane, they exhibit physical inconsistencies, such as morphing or vanishing objects, especially over long time horizons. In this paper, we propose FR3D, a world-modeling approach that predicts a persistent 3D latent representation for future dynamic 3D reconstruction. Unlike prior works that treat the world as a sequence of image-based features, FR3D explicitly decouples the 3D evolution of the scene from the agent's trajectory, treating the inferred ego-motion as a latent proxy for action. This disentanglement resolves ambiguities between self-motion and world-motion, ensuring geometric consistency into the future. Furthermore, we introduce a teacher-student distillation strategy that leverages the spatial "common sense" of off-the-shelf foundation models, leading to robust zero-shot generalization. Extensive experiments demonstrate FR3D's strong performance for future dynamic 3D reconstruction from monocular observations across multiple datasets, even 2 seconds into the future. Project page: https://fr3d-wm.github.io.

cs.CV↗

arXiv2026

OR-Action: Multi-Role Video Understanding with Fine-Grained Actions

Fine-grained understanding of operating room (OR) activity could enable workflow-aware assistance, yet remains difficult due to clutter, occlusions, and limited sensing. The prevailing approach to model this environment is scene graphs as an interpretable representation of OR interactions. Converting their frame-wise relational predictions into temporally extended, fine-grained actions however, is challenging without explicit temporal modeling. To enable a principled temporal evaluation of current OR understanding methods, we introduce the first action-centric benchmark built on a publicly available ego-exocentric OR dataset by defining a fine-grained, multi-role action taxonomy and generating dense action segments via distillation from ground-truth scene graph state changes. Experiments on this benchmark show that current scene graph prediction methods struggle to model temporal structure, even when adding explicit modeling through Graph Neural Networks. We therefore introduce a vision-only temporal model that outperforms graph-based methods significantly when using all available egocentric video as input. Building on this model we also introduce a novel multi- to single-view feature alignment strategy that improves single-view performance on multi-role action recognition, mitigating the need for extensive egocentric video capture. Benchmark and code will be released upon acceptance.

cs.CV↗

arXiv2026

DisPOSE: Projected Polystochastic Diffusion for Self-Supervised Multi-View 3D Human Pose Estimation

Recovering 3D human poses for multiple individuals from different camera views is a fundamental bottleneck for analyzing interacting behaviors. Existing self-supervised approaches leverage synthetic catalogues of 3D poses; however, this leads to poor generalization in real-world scenarios due to distribution shifts. We therefore introduce DisPOSE, a self-supervised framework that approximates the inherently discrete multi-view person-assignment problem as a generative diffusion process over the space of polystochastic tensors. By employing differentiable Sinkhorn projections during denoising, our model learns to guide solutions toward valid and feasible assignments based on 2D image priors. The complete 3D skeletons of localized individuals are then regressed using a Hypergraph-Convolutional Decoder that explicitly models relational structures and articulated joints across multiple views. The proposed approach outperforms current state-of-the-art self-supervised methods on standard datasets and demonstrates strong performance on a newly proposed benchmark featuring highly occluded scenes from surgical operating rooms. Our diffusion-based localization demonstrates high label efficiency, retaining 99% of its performance with only 10% of the pseudo-labels. Notably, disentangling the assignment and root regression components while maintaining differentiability makes DisPOSE nearly agnostic to different camera arrangements. Project site and code: https://wngtn.github.io/DisPOSE/

cs.CV↗

arXiv2026

DefSynUS: Real-time Patient-specific Intrahepatic Vessel Identification via Deformation-Aware CT-US Domain Adaptation

Purpose: Laparoscopic ultrasound (LUS) enhances the safety of liver surgery by visualizing intrahepatic vessels in real-time. Still, vessel identification remains difficult due to probe constraints, complex vascular structure, and tissue deformation. This work aims to enable real-time, patient-specific vessel identification that remains robust under deformation through deformable ultrasound augmentation. Methods: Preoperative CT vessel annotations are used to generate synthetic ultrasound data via optimized physics-based rendering, coupled with domain adaptation to intraoperative ultrasound. The rendering is trained end-to-end for vessel identification and patient-specificity, eliminating the need for preoperative ultrasound. A deformation-aware augmentation simulates realistic intraoperative motion and tissue deformation within the rendering pipeline. Results: In abdominal phantom and limited clinical feasibility experiments (single-case clinical evaluation), the framework achieved real-time intrahepatic vessel-branch identification, maintaining performance under new patient poses. Conclusion: The framework enables real-time vessel identification without preoperative ultrasound and supports technical feasibility, but multi-patient validation is still needed for generalizability and clinical feasibility.

cs.CV↗

arXiv2026

SA4Depth: Consistent Pose-Depth Scale Alignment for Self-Supervised Monocular Depth Estimation

Self-supervised depth estimation from monocular sequences relies on the joint learning of a depth and a pose network. Despite abundant research done to improve the depth network, efforts on the pose remain limited. In this context, even when depth is estimated up to scale, we highlight the importance of the alignment between the scene scales estimated by the pose and depth nets. Then, we introduce SA4Depth, an approach to improve this alignment and boost the depth predictions while keeping the inference time unchanged. Our proposed method uses the depth estimated during training to reproject learnable visual features across consecutive frames and refine the pose estimates by reducing feature alignment residuals. With our method, the estimated scene scales by the separate depth and pose networks are aligned, and the prediction scale consistency is improved across different sequences. Our differentiable refinement integrates seamlessly into existing self-supervised pipelines and substantially improves their depth estimates. We demonstrate this with extensive experiments both outdoors and indoors on KITTI, Cityscapes, and NYUv2. Additionally, results on KITTI Odometry confirm the effectiveness of our pose refinement. Our code is available at https://github.com/Runningchauncey/SA4Depth .

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