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Nebojsa Duric

Publications and source records attributed to Nebojsa Duric.

4 recordsLinked to original sources

Wave-Equation Migration Velocity Analysis for Multistatic Synthetic Aperture Ultrasound

Sound speed heterogeneities can create aberrations in B-mode ultrasound images by inducing tissue-dependent delays and diffractive effects that conventional beamforming does not incorporate. By using the Fourier split-step method to simulate pressure fields in heterogenous sound speed media, reverse-time migration (RTM) can reconstruct the B-mode image by cross-correlating transmitted and received pressure fields. As a result, RTM is differentiable with respect to sound speed. This enables the reconstruction of the sound speed profile that minimizes the aberration in the B-mode image. In seismic imaging, this form of diffraction tomography, known as wave-equation migration velocity analysis, can roughly be understood as a type of full-waveform inversion (FWI) that acts in the image domain rather than errors in the received channel data. This is the first work applying WEMVA to medical pulse-echo ultrasound imaging. Phantom experiments show dramatic improvements in image quality with measured improvements in point target resolution from 1.22$\pm$1.01 to 0.32$\pm$0.07 mm and lesion contrast from 3.05 to 4.39 dB.

physics.med-ph

Investigating the Use of Traveltime and Reflection Tomography for Deep Learning-Based Sound-Speed Estimation in Ultrasound Computed Tomography

Ultrasound computed tomography (USCT) quantifies acoustic tissue properties such as the speed-of-sound (SOS). Although full-waveform inversion (FWI) is an effective method for accurate SOS reconstruction, it can be computationally challenging for large-scale problems. Deep learning-based image-to-image learned reconstruction (IILR) methods can offer computationally efficient alternatives. This study investigates the impact of the chosen input modalities on IILR methods for high-resolution SOS reconstruction in USCT. The selected modalities are traveltime tomography (TT) and reflection tomography (RT), which produce a low-resolution SOS map and a reflectivity map, respectively. These modalities have been chosen for their lower computational cost relative to FWI and their capacity to provide complementary information: TT offers a direct SOS measure, while RT reveals tissue boundary information. Systematic analyses were facilitated by employing a virtual USCT imaging system with anatomically realistic numerical breast phantoms. Within this testbed, a supervised convolutional neural network (CNN) was trained to map dual-channel (TT and RT images) to a high-resolution SOS map. Single-input CNNs were trained separately using inputs from each modality alone (TT or RT) for comparison. The accuracy of the methods was systematically assessed using normalized root mean squared error (NRMSE), structural similarity index measure (SSIM), and peak signal-to-noise ratio (PSNR). For tumor detection performance, receiver operating characteristic analysis was employed. The dual-channel IILR method was also tested on clinical human breast data. Ensemble average of the NRMSE, SSIM, and PSNR evaluated on this clinical dataset were 0.2355, 0.8845, and 28.33 dB, respectively.

eess.IV

A forward model incorporating elevation-focused transducer properties for 3D full-waveform inversion in ultrasound computed tomography

Ultrasound computed tomography (USCT) is an emerging medical imaging modality that holds great promise for improving human health. Full-waveform inversion (FWI)-based image reconstruction methods account for the relevant wave physics to produce high spatial resolution images of the acoustic properties of the breast tissues. A practical USCT design employs a circular ring-array comprised of elevation-focused ultrasonic transducers, and volumentric imaging is achieved by translating the ring-array orthogonally to the imaging plane. In commonly deployed slice-by-slice (SBS) reconstruction approaches, the three-dimensional (3D) volume is reconstructed by stacking together two-dimensional (2D) images reconstructed for each position of the ring-array. A limitation of the SBS reconstruction approach is that it does not account for 3D wave propagation physics and the focusing properties of the transducers, which can result in significant image artifacts and inaccuracies. To perform 3D image reconstruction when elevation-focused transducers are employed, a numerical description of the focusing properties of the transducers should be included in the forward model. To address this, a 3D computational model of an elevation-focused transducer is developed to enable 3D FWI-based reconstruction methods to be deployed in ring-array-based USCT. The focusing is achieved by applying a spatially varying temporal delay to the ultrasound pulse (emitter mode) and recorded signal (receiver mode). The proposed numerical transducer model is quantitatively validated and employed in computer-simulation studies that demonstrate its use in image reconstruction for ring-array USCT

physics.med-ph

An X-ray, Optical and Radio Search for Supernova Remnants in the Nearby Sculptor Group Sd Galaxy NGC 7793

We present a multi-wavelength study of the properties of supernova remnants (SNRs) in the nearby Sculptor Group Sd galaxy NGC 7793. Using our own Very Large Array radio observations at 6 and 20 cm, as well as archived ROSAT X-ray data, previously published optical results and our own H-alpha image, we have searched for X-ray and radio counterparts to previously known optically-identified SNRs and for new previously unidentified SNRs at these two wavelength regimes. Only two of the 28 optically-identified SNRs are detected at another wavelength. The most noteworthy source in our study is N7793-S26, which is the only SNR that is detected at all three wavelengths. It features a long (approximately 450 pc) filamentary morphology that is clearly seen in both the optical and radio images. N7793-S26's radio luminosity exceeds that of the Galactic SNR Cas A, and based on equipartition calculations we determine that an energy of at least 10^52 ergs is required to maintain this source. A second optically identified SNR, N7793-S11, has detectable radio emission but is not detected in the X-ray. Complementary X-ray and radio searches for SNRs have yielded five new candidate radio SNRs, to be added to the 28 SNRs in this galaxy that have already been detected by optical methods. We find that the density of the ambient interstellar medium (ISM) surrounding these SNRs significantly impacts the spectral characteristics of SNRs in this galaxy, consistent with surveys of the SNR populations in other galaxies.

astro-ph