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Nhat Minh Le

Publications and source records attributed to Nhat Minh Le.

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Rethinking Code Performance Benchmarks for LLMs

Many function-level performance benchmarks have been proposed to evaluate whether large language models (LLMs) can generate efficient programs. However, results on these benchmarks often show that LLM-generated implementations have little or no execution-time difference from canonical solutions. In this paper, we revisit four popular benchmarks: EffiBench, Enamel, EvalPerf, and Mercury. We evaluate 1,538 tasks under more rigorous setting by running each task 30 times and assessing the runtime differences between the canonical solutions and benchmark-provided performant implementations with statistical testing. With the benchmark-provided test suites, only 6.11% of the performant implementations are significantly faster than the canonical solutions. In a manual analysis of 308 non-significant tasks, 99 performant implementations contain no meaningful performance change, while 209 contain potential performance improvements that are not exposed by the original tests. These results suggest that the main limitation is not only the evaluation method, but also the limited sufficiency of the benchmark-provided performance tests. To address this limitation, we propose an LLM-based multi-agent framework to generate performance-oriented tests that expose runtime differences more effectively than the original tests. The framework uses three separate agents to generate, diagnose, and repair deterministic tests that preserve functional correctness while better exposing performance differences. Across 1,345 benchmark tasks for which the original tests found no significant performance difference, tests generated by our framework with DeepSeek-v3.1 and GPT-4o reveal statistically significant improvements in 24.01% and 25.43% of the tasks, respectively, outperforming the SOTA LLM-based performance test generation method.

cs.SE

Learning biologically relevant features in a pathology foundation model using sparse autoencoders

Pathology plays an important role in disease diagnosis, treatment decision-making and drug development. Previous works on interpretability for machine learning models on pathology images have revolved around methods such as attention value visualization and deriving human-interpretable features from model heatmaps. Mechanistic interpretability is an emerging area of model interpretability that focuses on reverse-engineering neural networks. Sparse Autoencoders (SAEs) have emerged as a promising direction in terms of extracting monosemantic features from polysemantic model activations. In this work, we trained a Sparse Autoencoder on the embeddings of a pathology pretrained foundation model. We found that Sparse Autoencoder features represent interpretable and monosemantic biological concepts. In particular, individual SAE dimensions showed strong correlations with cell type counts such as plasma cells and lymphocytes. These biological representations were unique to the pathology pretrained model and were not found in a self-supervised model pretrained on natural images. We demonstrated that such biologically-grounded monosemantic representations evolved across the model's depth, and the pathology foundation model eventually gained robustness to non-biological factors such as scanner type. The emergence of biologically relevant SAE features was generalizable to an out-of-domain dataset. Our work paves the way for further exploration around interpretable feature dimensions and their utility for medical and clinical applications.

eess.IV