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Nicholas Bender

Publications and source records attributed to Nicholas Bender.

At least 19 recordsLinked to original sources

Tailored Speckle Illumination Microscopy with Enhanced Sectioning and Image Quality

Optical speckle patterns have been widely used for illumination in computational imaging, optical sectioning microscopy, and super-resolution imaging. However, commonly used speckles satisfy Rayleigh statistics, which are not ideal for diverse imaging applications. Here we tailor three-dimensional speckle intensity statistics for dynamic speckle illumination microscopy based on linear fluorescence. Optical sectioning is enhanced by axially varying speckle contrast, and image reconstruction noise is minimized with in-focus speckles of binary intensities. The customized speckle statistics are shown to tolerate sample-induced aberration and scattering. We apply tailored speckle illumination to mouse brain vascular imaging and demonstrate much improved image quality than optical-sectioning structured illumination. These results establish customization of speckle intensity statistics as a promising strategy for robust, high-throughput fluorescence imaging in thick, scattering biological specimens.

physics.optics

Generalized Time-Reversal for Pulse Control in Diffusive Media

Time-reversal symmetry allows waves to retrace their paths through complex media and refocus at their origin. However, incomplete capture and reversal of scattered waves often limits pulse recompression. We address this challenge for spatially extended sources by introducing a generalized time-reversal framework, which identifies the optimal source pattern as the one that maximizes the energy of the waves that are captured and reversed. In a two-dimensional diffusive waveguide, we reconstruct the time-reversed wavefront corresponding to this optimal source using spatiospectral shaping, leading to a 35-fold enhancement in peak transmitted power compared to an unmodulated pulse. Internal spatiotemporal measurements reveal a ``loading and firing" process, in which energy accumulates within the medium and then is released abruptly. Moreover, time-reversing this burst enables deep energy delivery into the scattering medium. Generalized time-reversal opens new possibilities for short-pulse control in strongly-scattering media, with applications ranging from optogenetics to random laser amplification.

physics.optics

Observation of stability of Gaussian beams and off-axis beam-cleaning in graded-index media

While nonlinear effects in graded-index (GRIN) multimode fibers have been studied extensively, little is known about nonlinear effects in larger GRIN waveguides, where the number of modes approaches infinity and modal dispersion becomes negligible. Here we show that Gaussian beams remain nearly invariant even with large nonlinear phase accumulation and on- or off-axis trajectories in GRIN rods. In addition, spatially-complex beams can undergo self-cleaning to single-lobed profiles for both on- and off-axis trajectories. Numerical simulations exhibit the features observed in experiments, and a general interpretation of these results that makes connection to beam-cleaning phenomena observed in GRIN fibers is proposed.

physics.optics

Spectral Width of Maximum Deposition Eigenchannels in Diffusive Media

The maximum deposition eigenchannel provides the largest possible power delivery to a target region inside a diffusive medium by optimizing the incident wavefront of a monochromatic beam. It originates from constructive interference of scattered waves, which is frequency sensitive. We investigate the spectral width of maximum deposition eigenchannels over a range of target depths using numerical simulations of a 2D diffusive system. Compared to tight focusing into the system, power deposition to an extended region is more sensitive to frequency detuning. The spectral width of enhanced delivery to a large target displays a rather weak, non-monotonic variation with target depth, in contrast to a sharp drop of focusing bandwidth with depth. While the maximum enhancement of power deposited within a diffusive system can exceed that of power transmitted through it, this comes at the cost of a narrower spectral width. We investigate the narrower deposition width in terms of the constructive interference of transmission eigenchannels within the target. We further observe that the spatial field distribution inside the target region decorrelates slower with spectral detuning than power decay of the maximum deposition eigenchannel. Additionally, absorption increases the spectral width of deposition eigenchannels, but the depth dependence remains qualitatively identical to that without absorption. These findings hold for any diffusive waves, including electromagnetic waves, acoustic waves, pressure waves, mesoscopic electrons, and cold atoms.

physics.optics

Delivering Broadband Light Deep Inside Diffusive Media

Wavefront shaping enables targeted delivery of coherent light into random-scattering media, such as biological tissue, by constructive interference of scattered waves. However, broadband waves have short coherence times, weakening the interference effect. Here, we introduce a broadband deposition matrix that identifies a single input wavefront that maximizes the broadband energy delivered to an extended target deep inside a diffusive system. We experimentally demonstrate that long-range spatial and spectral correlations result in a six-fold energy enhancement for targets containing more than 1500 speckle grains and located at a depth of up to ten transport mean free paths, even when the coherence time is an order of magnitude shorter than the diffusion dwell time of light in the scattering sample. In the broadband (fast decoherence) limit, enhancement of energy delivery to extended targets becomes nearly independent of the target depth and dissipation. Our experiments, numerical simulations, and analytic theory establish the fundamental limit for broadband energy delivery deep into a diffusive system, which has important consequences for practical applications.

physics.optics

Spectral Speckle Customization

Speckle patterns are used in a broad range of applications including microscopy, imaging, and light-matter interactions. Tailoring speckles' statistics can dramatically enhance their performance in applications. We present an experimental technique for customizing the spatio-spectral speckled intensity statistics of optical pulses at the output of a complex medium (a disordered multimode fiber) by controlling the spatial profile of the input light. We demonstrate that it is possible to create ensembles of independent speckle patterns with arbitrary statistics at a single wavelength, simultaneously at decorrelated wavelengths, and even tailored statistics across an entire pulse spectrum.

physics.optics

Creating high-contrast patterns in multiple-scattering media via wavefront shaping

Wavefront shaping allows focusing light through or inside strongly scattering media, but the background intensity also increases due to long-range correlations, reducing the target's contrast. By manipulating non-local intensity correlations of scattered waves in a disordered system with input wavefront shaping, we create high-contrast patterns behind strongly scattering media and targeted energy delivery into a diffusive system with minimal change in the surrounding intensity. These are achieved by introducing the contrast operator and the difference operator, and utilizing their eigenstates to maximize the target-to-background intensity contrast and energy difference. This work opens the door to coherent control of non-local effects in wave transport for practical applications.

physics.optics

Highly-Multimode Solitons in Step-Index Optical Fiber

We report the generation of multimode solitons in step-index fiber. The solitons are superpositions of 5-10 temporally-aligned transverse modes, they exhibit speckled beam profiles, and the spatio-spectral variation across the soliton can be complex. Greater understanding of multimode solitons should create a foundation for further research into complex multimode nonlinear phenomena in step-index fibers. With energies of tens of nanojoules and durations around 100 fs, the multimode solitons are speckled fields with peak powers that can exceeed 300 kW, parameters which may be valuable in applications.

physics.optics

Tailoring 3D Speckle Statistics

We experimentally generate three-dimensional speckles with customized intensity statistics. By modulating the phase front of a laser beam, far-field speckle patterns maintain the designed intensity probability density function while evolving to different spatial patterns upon axial propagation. We also create speckles with distinct intensity statistics at multiple designated planes. These results open many new possibilities, such as designing volumetric speckle statistics for three-dimensional imaging, sensing, trapping, and manipulation.

physics.optics

Sum rules for energy deposition eigenchannels in scattering systems

In a random-scattering system, the deposition matrix maps the incident wavefront to the internal field distribution across a target volume. The corresponding eigenchannels have been used to enhance the wave energy delivered to the target. Here we find the sum rules for the eigenvalues and eigenchannels of the deposition matrix in any system geometry: including two and three-dimensional scattering systems, as well as narrow waveguides and wide slabs. We derive a number of constraints on the eigenchannel intensity distributions inside the system as well as the corresponding eigenvalues. Our results are general and applicable to random systems of arbitrary scattering strength as well as different types of waves including electromagnetic waves, acoustic waves, and matter waves.

physics.optics

Coherent enhancement of optical remission in diffusive media

From the earth's crust to the human brain, remitted waves are used for sensing and imaging in a diverse range of diffusive media. Separating the source and detector increases the penetration depth of remitted light, yet rapidly decreases the signal strength, leading to a poor signal-to-noise ratio. Here, we experimentally and numerically show that wavefront shaping a laser beam incident on a diffusive sample enables an order of magnitude remission enhancement, with a penetration depth of up to 10 transport mean free paths. We develop a theoretical model which predicts the maximal-remission enhancement. Our analysis reveals a significant improvement in the sensitivity of remitted waves, to local changes of absorption deep inside diffusive media. This work illustrates the potential of coherent wavefront control for non-invasive diffuse-wave imaging applications, such as diffuse optical tomography and functional near-infrared spectroscopy.

physics.optics

Depth-Targeted Energy Deposition Deep Inside Scattering Media

A grand challenge in fundamental physics and practical applications is overcoming wave diffusion to deposit energy into a target region deep inside a diffusive system. While it is known that coherently controlling the incident wavefront allows diffraction-limited focusing inside a diffusive system, in many applications targets are significantly larger than such a focus and the maximum deliverable energy remains unknown. Here, we introduce the "deposition matrix", which maps an input wavefront to its internal field distribution, and theoretically predict the ultimate limitations on energy deposition at any depth. For example, the maximum obtainable energy enhancement occurs at 3/4 a diffusive system's thickness: regardless of its scattering strength. Experimentally we measure the deposition matrix and excite its eigenstates to enhance/suppress the energy within an extended target region. Our theoretical analysis reveals that such enhancement/suppression results from both selective transmission eigenchannel excitation and constructive/destructive interference among these channels.

physics.optics

Direct Observation of Thermalization to a Rayleigh-Jeans Distribution in Multimode Optical Fibers

Recent years have witnessed a resurgence of interest in nonlinear multimode optical systems where a host of intriguing effects have been observed that are impossible in single-mode settings. While nonlinearity can provide a rich environment where the chaotic power exchange among thousands of modes can lead to novel behaviors, at the same time, it poses a major challenge in terms of understanding and harnessing these processes to advantage. Over the years, statistical models have been developed to macroscopically describe the response of these complex systems. One of the cornerstones of these theoretical formalisms is the prediction of a photon-photon mediated thermalization process that leads to a Rayleigh-Jeans distribution of mode occupations. Here we report the use of mode-resolved measurement techniques to make the first direct observations of thermalization to a Rayleigh-Jeans power distribution in a multimode optical fiber. We experimentally demonstrate that the underlying system Hamiltonian remains invariant during propagation while power equipartition takes place among degenerate groups of modes - all in full accord with theoretical predictions. Our results may pave the way toward a new generation of high-power optical sources whose brightness and modal content can be controlled using principles from thermodynamics and statistical mechanics.

physics.optics

Circumventing the optical diffraction limit with customized speckles

Speckle patterns have been widely used in imaging techniques such as ghost imaging, dynamic speckle illumination microscopy, structured illumination microscopy, and photoacoustic fluctuation imaging. Recent advances in the ability to control the statistical properties of speckles has enabled the customization of speckle patterns for specific imaging applications. In this work, we design and create special speckle patterns for parallelized nonlinear pattern-illumination microscopy based on fluorescence photoswitching. We present a proof-of-principle experimental demonstration where we obtain a spatial resolution three times higher than the diffraction limit of the illumination optics in our setup. Furthermore, we show that tailored speckles vastly outperform standard speckles. Our work establishes that customized speckles are a potent tool in parallelized super-resolution microscopy.

physics.optics

Fluctuations and correlations of transmission eigenchannels in diffusive media

Selective excitation of a diffusive system's transmission eigenchannels enables manipulation of its internal energy distribution. The fluctuations and correlations of the eigenchannels' spatial profiles, however, remain unexplored so far. Here we show that the depth profiles of high-transmission eigenchannels exhibit low realization-to-realization fluctuations. Furthermore, our experimental and numerical studies reveal the existence of inter-channel correlations, which are significant for low-transmission eigenchannels. Because high-transmission eigenchannels are robust and independent from other eigenchannels, they can reliably deliver energy deep inside turbid media.

cond-mat.dis-nn

Creating and Controlling Complex Light

Random light fields -- commonly known as speckles -- demonstrate Rayleigh intensity statistics and only possess local correlations: which occur within the individual speckle grains. In this work, we develop an experimental method for customizing the intensity probability density function (PDF) of speckle patterns while simultaneously introducing non-local spatial correlations among the speckle grains. The various families of tailored speckle patterns -- created by our method -- can exhibit radically different topologies, statistics, and variable degrees of spatial order. Irrespective of their distinct statistical properties, however, all of these speckles are created by appropriately encoding high-order correlations into the phase front of a monochromatic laser beam with a spatial light modulator. In addition to our experimental demonstration, we explore both the theoretical and practical limitations on the extent to which the intensity PDF and the spatial intensity correlations can be manipulated concurrently in a speckle pattern. This work provides a versatile methodology for creating complex light fields and controlling their statistical properties with varied applications in microscopy, imaging, and optical manipulation.

physics.optics

Introducing non-local correlations into speckles

Laser speckles have become a fundamental component of the modern optics-research toolbox. Not only are speckle patterns the basis of numerous imaging techniques, but also, they are employed to generate optical potentials for cold atoms and colloidal particles. The ability to manipulate a speckle pattern's spatial intensity correlations, particularly long-range (non-local) ones, is essential in numerous applications. A typical fully-developed speckle pattern, however, only possesses short-ranged (local) intensity correlations which are determined by the spatial field correlations. Here we experimentally demonstrate and theoretically develop a general method for creating fully-developed speckles with strong non-local intensity correlations. The functional form of the spatial intensity correlations can be arbitrarily tailored without altering the field correlations. Our approach provides a versatile and utilitarian framework for enhancing and controlling non-local correlations in speckle patterns.

physics.optics

Customizing Speckle Intensity Statistics

We develop a general method for customizing the intensity statistics of speckle patterns on a target plane. By judiciously modulating the phase-front of a monochromatic laser beam, we experimentally generate speckle patterns with arbitrarily-tailored intensity probability-density functions. Relative to Rayleigh speckles, our customized speckles exhibit radically different topologies yet maintain the same spatial correlation length. The customized speckles are fully developed, ergodic, and stationary: with circular non-Gaussian statistics for the complex field. Propagating away from the target plane, the customized speckles revert back to Rayleigh speckles. This work provides a versatile framework for tailoring speckle patterns with varied applications in microscopy, imaging and optical manipulation.

physics.optics