arXiv subjects

Nicolas Rubido

Publications and source records attributed to Nicolas Rubido.

5 recordsLinked to original sources

arXiv2025

Improved classification of Alzheimer's disease and mild cognitive impairment through dynamic functional network analysis

Brain networks from functional MRI have advanced our understanding of cortical activity and its disruption in neurodegenerative disorders. Recent work has increasingly focused on dynamic (time-varying) brain networks that capture both spatial and temporal patterns of regional co-activity, yet this approach remains underexplored across the Alzheimer's disease (AD). We analysed age- and sex-matched static and dynamic functional brain networks derived from resting-state fMRI data in 315 individuals with AD, mild cognitive impairment (MCI), and cognitively normal healthy controls (HC) from the ADNI-3 cohort. Functional networks were constructed using the Juelich brain atlas, with static connectivity estimated from full time series and dynamic connectivity derived using a sliding-window approach. Group differences were assessed at both link and node levels using non-parametric statistics and bootstrap resampling. While HC and MCI exhibited similar static and dynamic patterns at the node level, clearer differences emerged in AD. Stable (stationary) differences in functional connectivity were identified between white matter regions and parietal and somatosensory cortices, whereas temporally varying differences were consistently observed in connections involving the amygdala and hippocampal formation. Node centrality analysis further suggested that white matter connectivity differences are predominantly local in nature. These findings highlight both shared and distinct functional connectivity patterns across static and dynamic networks, underscoring the importance of incorporating temporal dynamics into brain network analyses of the Alzheimer's spectrum. Additionally, a Random Forest model trained on regional BOLD time series informed by static and dynamic metrics achieved robust classification of MCI, AD, and HC groups, demonstrating the diagnostic potential of time-varying connectivity.

q-bio.NC↗

arXiv2018

Impact of lag information on network inference

Extracting useful information from data is a fundamental challenge across disciplines as diverse as climate, neuroscience, genetics, and ecology. In the era of ``big data'', data is ubiquitous, but appropriated methods are needed for gaining reliable information from the data. In this work we consider a complex system, composed by interacting units, and aim at inferring which elements influence each other, directly from the observed data. The only assumption about the structure of the system is that it can be modeled by a network composed by a set of $N$ units connected with $L$ un-weighted and un-directed links, however, the structure of the connections is not known. In this situation the inference of the underlying network is usually done by using interdependency measures, computed from the output signals of the units. We show, using experimental data recorded from randomly coupled electronic R{ö}ssler chaotic oscillators, that the information of the lag times obtained from bivariate cross-correlation analysis can be useful to gain information about the real connectivity of the system.

nlin.CD↗

arXiv2015

Electronically--implemented coupled logistic maps

The logistic map is a paradigmatic dynamical system originally conceived to model the discrete-time demographic growth of a population, which shockingly, shows that discrete chaos can emerge from trivial low-dimensional non-linear dynamics. In this work, we design and characterize a simple, low-cost, easy-to-handle, electronic implementation of the logistic map. In particular, our implementation allows for straightforward circuit-modifications to behave as different one-dimensional discrete-time systems. Also, we design a coupling block in order to address the behavior of two coupled maps, although, our design is unrestricted to the discrete-time system implementation and it can be generalized to handle coupling between many dynamical systems, as in a complex system. Our findings show that the isolated and coupled maps' behavior has a remarkable agreement between the experiments and the simulations, even when fine-tuning the parameters with a resolution of $\sim 10^{-3}$. We support these conclusions by comparing the Lyapunov exponents, periodicity of the orbits, and phase portraits of the numerical and experimental data for a wide range of coupling strengths and map's parameters.

nlin.CD↗

arXiv2015

Approximate solution for frequency synchronisation in a finite-size Kuramoto model

Scientists have been considering the Kuramoto model to understand the mechanism behind the appearance of collective behaviour, such as frequency synchronisation (FS) as a paradigm, in real-world networks with a finite number of oscillators. A major current challenge is to obtain an analytical solution for the phase-angles. Here, we provide an approximate analytical solution for this problem by deriving a master solution for the finite-size Kuramoto model, without imposing any restriction on the distribution of the natural frequencies of the oscillators. The master solution embodies all particular solutions of the finite-size Kuramoto model for any frequency distribution and coupling strength larger than the critical one. Furthermore, we present a criterion to determine the stability of the FS solution. This allows one to analytically infer the relationship between the physical parameters and the stable behaviour of networks.

nlin.AO↗

arXiv2014

Models for the modern power grid

This article reviews different kinds of models for the electric power grid that can be used to understand the modern power system, the smart grid. From the physical network to abstract energy markets, we identify in the literature different aspects that co-determine the spatio-temporal multilayer dynamics of power system. We start our review by showing how the generation, transmission and distribution characteristics of the traditional power grids are already subject to complex behaviour appearing as a result of the the interplay between dynamics of the nodes and topology, namely synchronisation and cascade effects. When dealing with smart grids, the system complexity increases even more: on top of the physical network of power lines and controllable sources of electricity, the modernisation brings information networks, renewable intermittent generation, market liberalisation, prosumers, among other aspects. In this case, we forecast a dynamical co-evolution of the smart grid and other kind of networked systems that cannot be understood isolated. This review compiles recent results that model electric power grids as complex systems, going beyond pure technological aspects. From this perspective, we then indicate possible ways to incorporate the diverse co-evolving systems into the smart grid model using, for example, network theory and multi-agent simulation.

eess.SY↗