arXiv subjects

Nicole Seiberlich

Publications and source records attributed to Nicole Seiberlich.

5 recordsLinked to original sources

arXiv2026

Dynamic MRI Reconstruction Via Dual Deep Priors and Low-Rank Plus Sparse Modeling

Dynamic MRI reconstruction from undersampled measurements is a challenging inverse problem that requires preserving both spatial reconstruction quality and temporal consistency across the frames of the cine series. While recent learning-based approaches achieve strong performance, they heavily rely on large training, mostly fully sampled, datasets, and may otherwise generalize poorly. In contrast, training-data-free methods such as deep image prior (DIP) adapt directly to individual scans but often fail to fully exploit temporal structure and are prone to overfitting. They are particularly attractive for dynamic MRI due to the limited large, public, high-quality datasets. In this work, we propose a structured DIP framework for dynamic MRI reconstruction that explicitly models spatiotemporal correlations through a low-rank plus sparse (L+S) decomposition. Instead of directly reconstructing the cine image series, we parameterize the low-rank background and sparse dynamic components using two DIP untrained convolutional neural networks, jointly optimized using accelerated extrapolated ADMM (eADMM). This formulation combines the implicit regularization of DIP with the interpretability of classical L+S regularization. We provide a convergence analysis for the proposed eADMM algorithm in the presence of DIP-based nonconvex parameterizations. In particular, we establish a sufficient descent property and show that every cluster point of the generated sequence is a critical point of the associated Lyapunov function. Across various acceleration factors, our numerical results demonstrate that the proposed method consistently outperforms classical reconstruction and existing supervised and unsupervised MRI reconstruction techniques.

eess.IV↗

arXiv2026

OpenMRF: A Modular, Vendor-Neutral Open-Source Framework for Reproducible Magnetic Resonance Fingerprinting using Pulseq

Purpose: Widespread adoption and methodological advancement of Magnetic Resonance Fingerprinting (MRF) are limited by the lack of unified, reproducible implementation frameworks and fragmented open-source tools. To address these barriers, we introduce OpenMRF - a comprehensive Pulseq-based solution - designed to enable consistent, reproducible, and transferable MRF research across vendors, sites, and field strengths. Methods: OpenMRF integrates modular Pulseq-based sequence design, Bloch-simulation-based dictionary creation directly from .seq files, and iterative low-rank subspace reconstruction. The framework was evaluated through digital phantom simulations, a multi-site ISMRM/NIST phantom study on Siemens MRI systems at 0.55 T, 1.5 T, and 3 T as well as GE and United Imaging 3 T platforms, and representative in vivo acquisitions in the liver (0.55 T), myocardium (1.5 T), and brain (3 T). Results: Simulations demonstrated high mapping accuracy in an ISMRM/NIST-like digital phantom, with low-rank reconstruction yielding deviations of 0.03+/-0.32 % (T1) and 0.12+/-1.94 % (T2). The multi-site phantom study yielded relaxation times consistent with reference values at all field strengths, with mean deviations of -0.1+/-2.9 % (T1), -1.5+/-8.7 % (T2), and -4.0+/-7.2 % (T1rho). In vivo acquisitions produced high-quality parameter maps across platforms and field strengths. Conclusion: OpenMRF provides a robust, open-source, end-to-end Pulseq-based solution for MRF that enables reproducible sequence implementation, physics-accurate dictionary simulation, and advanced reconstruction across vendors and field strengths. By providing a unified platform for method development, comparison, and multi-site validation, OpenMRF aims to accelerate reproducible and harmonized quantitative MRI research within the community.

physics.med-ph↗

arXiv2026

Scan-Adaptive Dynamic MRI Undersampling Using a Dictionary of Efficiently Learned Patterns

Cardiac MRI is limited by long acquisition times, which can lead to patient discomfort and motion artifacts. We aim to accelerate Cartesian dynamic cardiac MRI by learning efficient, scan-adaptive undersampling patterns that preserve diagnostic image quality. We develop a learning-based framework for designing scan- or slice-adaptive Cartesian undersampling masks tailored to dynamic cardiac MRI. Undersampling patterns are optimized using fully sampled training dynamic time-series data. At inference time, a nearest-neighbor search in low-frequency $k$-space selects an optimized mask from a dictionary of learned patterns. Our learned sampling approach improves reconstruction quality across multiple acceleration factors on public and in-house cardiac MRI datasets, including PSNR gains of 2-3 dB, reduced NMSE, improved SSIM, and higher radiologist ratings. The proposed scan-adaptive sampling framework enables faster and higher-quality dynamic cardiac MRI by adapting $k$-space sampling to individual scans.

eess.IV↗

arXiv2025

Scan-Adaptive MRI Undersampling Using Neighbor-based Optimization (SUNO)

Accelerated MRI involves collecting partial $k$-space measurements to reduce acquisition time, patient discomfort, and motion artifacts, and typically uses regular undersampling patterns or human-designed schemes. Recent works have studied population-adaptive sampling patterns learned from a group of patients (or scans). However, such patterns can be sub-optimal for individual scans, as they may fail to capture scan or slice-specific details, and their effectiveness can depend on the size and composition of the population. To overcome this issue, we propose a framework for jointly learning scan-adaptive Cartesian undersampling patterns and a corresponding reconstruction model from a training set. We use an alternating algorithm for learning the sampling patterns and the reconstruction model where we use an iterative coordinate descent (ICD) based offline optimization of scan-adaptive $k$-space sampling patterns for each example in the training set. A nearest neighbor search is then used to select the scan-adaptive sampling pattern at test time from initially acquired low-frequency $k$-space information. We applied the proposed framework (dubbed SUNO) to the fastMRI multi-coil knee and brain datasets, demonstrating improved performance over the currently used undersampling patterns at both $4\times$ and $8\times$ acceleration factors in terms of both visual quality and quantitative metrics. The code for the proposed framework is available at https://github.com/sidgautam95/adaptive-sampling-mri-suno. This paper has been accepted for publication in IEEE Transactions on Computational Imaging. The final published version is available at https://doi.org/10.1109/TCI.2026.3653330.

eess.IV↗

arXiv2024

Comparative Study of RF Heating in Deep Brain Stimulation Devices During MRI at 1.5 T and 0.55 T: Challenging the Assumption of Safety at Low Field Strengths

Purpose: Low-field MRI has been assumed to be implant-friendly based on limited studies. However, RF-induced heating due to an implant is a complex resonance phenomenon, highly dependent on the implant's configurations and the applied RF frequencies. This study aims to evaluate the RF heating of DBS implants during MRI at low-field strengths compared to higher field 1.5 T MRI. Methods: A commercial deep brain stimulation (DBS) implant was used in full system as well as lead only configurations to evaluate and compare RF heating during MR imaging at 0.55 T and 1.5 T. The transfer function of the device at both configurations was measured and validated at each of the frequencies, which was then used for the in vivo prediction of RF heating for realistic DBS configurations at head, chest and abdomen imaging landmarks. Results: For the lead only case, the RF heating due to the DBS was substantially smaller during imaging at 0.55 T compared to that at 1.5 T. However, for the full DBS system (longer implant), the RF heating at 0.55 T was comparable to and for some cases even higher than that at 1.5 T, reaching a level that poses risk of tissue damage in patients. Conclusions: While RF heating generally tends to be lower at low-field MRI, the case with longer implanted leads demands extra caution, due to the higher possibility of matching resonant condition at low-field-strength frequencies. Thus, specific risk evaluation for each implant and configuration is required rather than assuming that lower field strength imaging is safer.

physics.med-ph↗