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Niklas C. Koser

Publications and source records attributed to Niklas C. Koser.

3 recordsLinked to original sources

Option-Aware Retrieval and Task-Specific VLM Adaptation for Medical VQA

We describe our submission to the MedReason 2026 challenge, covering multiple-choice (MCQ) and open-ended (OE) medical visual question answering (VQA) under fully offline, containerized inference. Our first finding is that MCQ retrieval must compare answer \emph{semantics} rather than answer labels: labels are independently assigned per question, so copying a retrieved neighbor's label transfers no useful information, whereas scoring each current option's text against correct-answer text from similar training cases raises retrieval-only accuracy from 20.0\% to 57.5\% on a 200-case retrieval-excluded development holdout. Our second finding attributes the submitted system's accuracy: holding the task-specific MCQ Low-Rank Adaptation (LoRA) adapter fixed and varying the number \(k\) of in-prompt retrieved examples changes accuracy by at most one case --- 187/200 (93.5\%) at both \(k=0\) and the adapter's training-time \(k=1\), 188/200 (94.0\%) at the packaged runtime's default \(k=3\) --- and the submitted confidence-gated override adds no net accuracy on top of \(k=3\), selecting the VLM in 198/200 cases. With the final MCQ adapter fixed, retrieval changes accuracy by at most one case, and gating provides no net gain. On 20 OE cases, token-F1 and RaTEScore~\cite{zhao2024ratescore} decrease as \(k\) grows, but paired sign tests on token-F1 differences are nonsignificant (\(p \ge 0.29\)); a single-annotator comparison found 6/20 wrong-anchor errors for the final configuration and 14/20 for an earlier configuration that jointly differed in routing, adapter, and prompting. The system reaches 94.0\% MCQ accuracy on the development holdout and 93.20\% on the organizer's official pre-evaluation, versus 29.43\% for the off-the-shelf reference baseline, while both of the organizer's open-ended scores are lower than that baseline's (ground-truth agreement 1.245 versus 1.588, visual accuracy 1.995 versus 2.696, each out of 4).

cs.AI

SynVA: A Modular Toolkit for Vessel Generation and Aneurysm Editing

Intracranial aneurysms (IAs), characterized by unpredictable growth and risk of rupture, are a major cause of stroke and can lead to life-threatening hemorrhages with high mortality and long-term disability. With aging populations, the incidence and overall burden of cerebrovascular diseases are expected to increase, highlighting the need for scalable approaches to analyze complex medical data and improve population-level understanding of these conditions. While digital twins and deep learning offer promising avenues for improving diagnosis, prognosis, and treatment, their effectiveness is limited by the scarcity of large-scale, high-quality medical data and corresponding labels. We present Synthetic VAsculature (SynVA), a modular toolkit for vascular mesh generation and anatomically consistent aneurysm synthesis. SynVA combines novel flow-matching-based methods for generating healthy vessel meshes with learning-based approaches for anatomy-conditioned aneurysm mesh generation - aneurysms are computed from pre-existing vascular geometries rather than being generated in isolation. In addition, we introduce the SynVA procedural model for vascular and aneurysm synthesis based solely on physiological principles and statistical priors, which enables the generation of large-scale datasets (e.g., for the training of mesh-based generative models). To this end, we release a dataset of 50,000 fully labeled mesh samples for a variety of downstream vision tasks, such as semantic segmentation. Extensive quantitative and qualitative evaluations demonstrate that SynVA generates realistic vessel geometries and anatomically plausible aneurysms. Specifically, our experiments indicate that some methods produce aneurysm shapes more aligned with expert human perception while others perform better on quantitative similarity metrics with reconstructions of real aneurysms.

cs.CV

Useful nonrobust features are ubiquitous in biomedical images

We study whether deep networks for medical imaging learn useful nonrobust features - predictive input patterns that are not human interpretable and highly susceptible to small adversarial perturbations - and how these features impact test performance. We show that models trained only on nonrobust features achieve well above chance accuracy across five MedMNIST classification tasks, confirming their predictive value in-distribution. Conversely, adversarially trained models that primarily rely on robust features sacrifice in-distribution accuracy but yield markedly better performance under controlled distribution shifts (MedMNIST-C). Overall, nonrobust features boost standard accuracy yet degrade out-of-distribution performance, revealing a practical robustness-accuracy trade-off in medical imaging classification tasks that should be tailored to the requirements of the deployment setting.

eess.IV