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Nusrat Binta Nizam

Publications and source records attributed to Nusrat Binta Nizam.

6 recordsLinked to original sources

Mammography Foundation Models for Opportunistic Prediction of Major Adverse Cardiovascular Events

Cardiovascular disease (CVD) remains the leading cause of death among women, yet cardiovascular risk assessment often relies on clinical variables that may be missing, outdated, or unavailable in routine care. Screening mammography offers an opportunity for opportunistic cardiovascular risk stratification because it is routinely acquired and contains vascular features, including breast arterial calcifications (BAC), that are associated with cardiovascular risk and events. We evaluate whether mammography specific foundation models, originally pretrained for breast cancer-related tasks, can transfer to cardiovascular risk prediction without cardiovascular specific supervision or explicit BAC annotation. We constructed a 5-year major adverse cardiovascular event (MACE) cohort of 22,497 women linked to electronic health record outcomes, including 500 events (2.22% prevalence). The foundation models achieved AUROCs of 0.823 and 0.822 substantially exceeding an age-only model (AUROC 0.765), despite using only the screening mammogram as input, with no clinical variables. Both foundation models evaluated assigned substantially higher predicted risk to patients with radiologist-documented BAC, despite BAC never being used as a training label, and showed activation patterns consistent with vascular findings. Together, these findings suggest that mammography foundation models can recover clinically relevant cardiovascular risk information directly from mammographic pixels and suggest that screening mammography may provide an opportunistic source of cardiovascular risk information to complement conventional clinical assessment without additional imaging. Code is available in https://github.com/PauFeld/MammoCVD

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ShapKO: Shapley-Adaptive Modality Knockout for Robust Multimodal Learning

Multimodal medical models often degrade when inputs are missing, a common scenario in real-world clinical workflows. Separately, even when all modalities are present, modality dominance is observed during training, where optimization over-relies on a highly predictive modality and undertrains complementary sources, resulting in poor robustness under partial availability. While training-time modality knockout improves missing-modality robustness, existing approaches use static masking rates that cannot adapt to evolving modality utility during training. We introduce ShapKO (Shapley-Adaptive Modality Knockout), a dynamic training strategy that learns modality-specific knockout probabilities based on validation utility. ShapKO periodically evaluates performance across modality subsets, estimates modality importance via Shapley values, and updates masking probabilities to suppress dominant modalities more frequently. This adaptive process promotes complementary representations, while requiring no architectural modifications. We evaluate ShapKO on three datasets covering multitask clinical classification, survival prediction, and cancer detection. ShapKO consistently improves performance under modality absence and yields interpretable trajectories of learned masking behavior. Code is available at: https://github.com/sumona00/ShapKO

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HyperCT: Low-Rank Hypernet for Unified Chest CT Analysis

Non-contrast chest CTs offer a rich opportunity for both conventional pulmonary and opportunistic extra-pulmonary screening. While Multi-Task Learning (MTL) can unify these diverse tasks, standard hard-parameter sharing approaches are often suboptimal for modeling distinct pathologies. We propose HyperCT, a framework that dynamically adapts a Vision Transformer backbone via a Hypernetwork. To ensure computational efficiency, we integrate Low-Rank Adaptation (LoRA), allowing the model to regress task-specific low-rank weight updates rather than full parameters. Validated on a large-scale dataset of radiological and cardiological tasks, \method{} outperforms various strong baselines, offering a unified, parameter-efficient solution for holistic patient assessment. Our code is available at https://github.com/lfb-1/HyperCT.

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BUET Multi-disease Heart Sound Dataset: A Comprehensive Auscultation Dataset for Developing Computer-Aided Diagnostic Systems

Cardiac auscultation, an integral tool in diagnosing cardiovascular diseases (CVDs), often relies on the subjective interpretation of clinicians, presenting a limitation in consistency and accuracy. Addressing this, we introduce the BUET Multi-disease Heart Sound (BMD-HS) dataset - a comprehensive and meticulously curated collection of heart sound recordings. This dataset, encompassing 864 recordings across five distinct classes of common heart sounds, represents a broad spectrum of valvular heart diseases, with a focus on diagnostically challenging cases. The standout feature of the BMD-HS dataset is its innovative multi-label annotation system, which captures a diverse range of diseases and unique disease states. This system significantly enhances the dataset's utility for developing advanced machine learning models in automated heart sound classification and diagnosis. By bridging the gap between traditional auscultation practices and contemporary data-driven diagnostic methods, the BMD-HS dataset is poised to revolutionize CVD diagnosis and management, providing an invaluable resource for the advancement of cardiac health research. The dataset is publicly available at this link: https://github.com/mHealthBuet/BMD-HS-Dataset.

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Anatomy-XNet: An Anatomy Aware Convolutional Neural Network for Thoracic Disease Classification in Chest X-rays

Thoracic disease detection from chest radiographs using deep learning methods has been an active area of research in the last decade. Most previous methods attempt to focus on the diseased organs of the image by identifying spatial regions responsible for significant contributions to the model's prediction. In contrast, expert radiologists first locate the prominent anatomical structures before determining if those regions are anomalous. Therefore, integrating anatomical knowledge within deep learning models could bring substantial improvement in automatic disease classification. Motivated by this, we propose Anatomy-XNet, an anatomy-aware attention-based thoracic disease classification network that prioritizes the spatial features guided by the pre-identified anatomy regions. We adopt a semi-supervised learning method by utilizing available small-scale organ-level annotations to locate the anatomy regions in large-scale datasets where the organ-level annotations are absent. The proposed Anatomy-XNet uses the pre-trained DenseNet-121 as the backbone network with two corresponding structured modules, the Anatomy Aware Attention (A$^3$) and Probabilistic Weighted Average Pooling (PWAP), in a cohesive framework for anatomical attention learning. We experimentally show that our proposed method sets a new state-of-the-art benchmark by achieving an AUC score of 85.78%, 92.07%, and, 84.04% on three publicly available large-scale CXR datasets--NIH, Stanford CheXpert, and MIMIC-CXR, respectively. This not only proves the efficacy of utilizing the anatomy segmentation knowledge to improve the thoracic disease classification but also demonstrates the generalizability of the proposed framework.

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Android Based Low Cost Sitting Posture Monitoring System

Back pain is one of the leading causes of disability-adjusted life year globally and the most common cause of low back pain is poor sitting posture. There are several actions that can be adopted proactively to avoid poor sitting posture induced back pain including behavioral change, regular exercise, and use of an ergonomic chair. However, these are either expensive and/or difficult to execute for prolonged periods. Sitting posture monitoring systems continuously observe the sitting pattern of a person in real-time and give feedback/alert poor sitting posture is observed. In this study, a real-time posture monitoring system has been designed and a functional prototype has been developed using simple electrical elements and an android application. Appropriate position of the sensor in the spine to measure the degree of bending and the threshold sensor values for good posture sittings have been determined based on the results from healthy volunteers of different ages and height. The android application continuously monitors the degree of bending and provides vibration when the bending reaches the threshold of bad posture or the duration of the sitting crosses the clinically recommended time limit to prevent prolonged sitting. Positive user feedback has been received in terms of comfortability, effectiveness, and satisfaction levels. The manufacturing cost of the developed monitoring system is minimal compared to the available expensive systems in the market and the cost would further go down if it is produced in bulk. This device efficiently monitors the sitting posture pattern to prevent back pain and within the affordable price range for the people from middle to under-developed countries.

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