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Oliver Stoner

Publications and source records attributed to Oliver Stoner.

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A unifying modelling approach for hierarchical distributed lag models

We present a statistical modelling framework for implementing Distributed Lag Models (DLMs), encompassing several extensions of the approach to capture the temporally distributed effect from covariates via regression. We place DLMs in the context of penalised Generalized Additive Models (GAMs) and illustrate that implementation via the R package \texttt{mgcv}, which allows for flexible and interpretable inference in addition to thorough model assessment. We show how the interpretation of penalised splines as random quantities enables approximate Bayesian inference and hierarchical structures in the same practical setting. We focus on epidemiological studies and demonstrate the approach with application to mortality data from Cyprus and Greece. For the Cyprus case study, we investigate for the first time, the joint lagged effects from both temperature and humidity on mortality risk with the unexpected result that humidity severely increases risk during cold rather than hot conditions. Another novel application is the use of the proposed framework for hierarchical pooling, to estimate district-specific covariate-lag risk on morality and the use of posterior simulation to compare risk across districts.

stat.ME

A Powerful Modelling Framework for Nowcasting and Forecasting COVID-19 and Other Diseases

The COVID-19 pandemic has highlighted delayed reporting as a significant impediment to effective disease surveillance and decision-making. In the absence of timely data, statistical models which account for delays can be adopted to nowcast and forecast cases or deaths. We discuss the four key sources of systematic and random variability in available data for COVID-19 and other diseases, and critically evaluate current state-of-the-art methods with respect to appropriately separating and capturing this variability. We present a general spatio-temporal hierarchical framework for correcting delayed reporting and demonstrate its application to daily English hospital deaths from COVID-19 and Severe Acute Respiratory Infection cases in Brazil. We compare our approach to competing models with respect to theoretical flexibility and quantitative metrics from a rolling nowcasting experiment imitating a realistic operational scenario. Based on consistent and compelling leads in nowcasting accuracy, bias, and precision, we demonstrate that our approach represents the current best-practice for correcting delayed reporting.

stat.AP

Modelling reporting delays for disease surveillance data

One difficulty for real-time tracking of epidemics is related to reporting delay. The reporting delay may be due to laboratory confirmation, logistic problems, infrastructure difficulties and so on. The ability to correct the available information as quickly as possible is crucial, in terms of decision making such as issuing warnings to the public and local authorities. A Bayesian hierarchical modelling approach is proposed as a flexible way of correcting the reporting delays and to quantify the associated uncertainty. Implementation of the model is fast, due to the use of the integrated nested Laplace approximation (INLA). The approach is illustrated on dengue fever incidence data in Rio de Janeiro, and Severe Acute Respiratory Illness (SARI) data in Paraná state, Brazil.

stat.AP

Global Household Energy Model: A Multivariate Hierarchical Approach to Estimating Trends in the Use of Polluting and Clean Fuels for Cooking

In 2017 an estimated 3 billion people used polluting fuels and technologies as their primary cooking solution, with 3.8 million deaths annually attributed to household exposure to the resulting fine particulate matter air pollution. Currently, health burdens are calculated using aggregations of fuel types, e.g. solid fuels, as country-level estimates of the use of specific fuel types, e.g. wood and charcoal, are unavailable. To expand the knowledge base about impacts of household air pollution on health, we develop and implement a Bayesian hierarchical model, based on Generalized Dirichlet Multinomial distributions, that jointly estimates non-linear trends in the use of eight key fuel types, overcoming several data-specific challenges including missing or combined fuel use values. We assess model fit using within-sample predictive analysis and an out-of-sample prediction experiment to evaluate the model's forecasting performance.

stat.AP

An Advanced Hidden Markov Model for Hourly Rainfall Time Series

For hydrological applications, such as urban flood modelling, it is often important to be able to simulate sub-daily rainfall time series from stochastic models. However, modelling rainfall at this resolution poses several challenges, including a complex temporal structure including long dry periods, seasonal variation in both the occurrence and intensity of rainfall, and extreme values. We illustrate how the hidden Markov framework can be adapted to construct a compelling model for sub-daily rainfall, which is capable of capturing all of these important characteristics well. These adaptations include clone states and non-stationarity in both the transition matrix and conditional models. Set in the Bayesian framework, a rich quantification of both parametric and predictive uncertainty is available, and thorough model checking is made possible through posterior predictive analyses. Results from the model are interpretable, allowing for meaningful examination of seasonal variation and medium to long term trends in rainfall occurrence and intensity. To demonstrate the effectiveness of our approach, both in terms of model fit and interpretability, we apply the model to an 8-year long time series of hourly observations.

stat.AP

Multivariate Hierarchical Frameworks for Modelling Delayed Reporting in Count Data

In many fields and applications count data can be subject to delayed reporting. This is where the total count, such as the number of disease cases contracted in a given week, may not be immediately available, instead arriving in parts over time. For short term decision making, the statistical challenge lies in predicting the total count based on any observed partial counts, along with a robust quantification of uncertainty. In this article we discuss previous approaches to modelling delayed reporting and present a multivariate hierarchical framework where the count generating process and delay mechanism are modelled simultaneously. Unlike other approaches, the framework can also be easily adapted to allow for the presence of under-reporting in the final observed count. To compare our approach with existing frameworks, one of which we extend to potentially improve predictive performance, we present a case study of reported dengue fever cases in Rio de Janeiro. Based on both within-sample and out-of-sample posterior predictive model checking and arguments of interpretability, adaptability, and computational efficiency, we discuss the advantages and disadvantages of each modelling framework.

stat.AP

A Hierarchical Framework for Correcting Under-Reporting in Count Data

Tuberculosis poses a global health risk and Brazil is among the top twenty countries by absolute mortality. However, this epidemiological burden is masked by under-reporting, which impairs planning for effective intervention. We present a comprehensive investigation and application of a Bayesian hierarchical approach to modelling and correcting under-reporting in tuberculosis counts, a general problem arising in observational count data. The framework is applicable to fully under-reported data, relying only on an informative prior distribution for the mean reporting rate to supplement the partial information in the data. Covariates are used to inform both the true count generating process and the under-reporting mechanism, while also allowing for complex spatio-temporal structures. We present several sensitivity analyses based on simulation experiments to aid the elicitation of the prior distribution for the mean reporting rate and decisions relating to the inclusion of covariates. Both prior and posterior predictive model checking are presented, as well as a critical evaluation of the approach.

stat.AP