arXiv subjects

Osmar R. Zaiane

Publications and source records attributed to Osmar R. Zaiane.

At least 19 recordsLinked to original sources

arXiv2026

Exploring Subnetwork Interactions in Heterogeneous Brain Network via Prior-Informed Graph Learning

Modeling the complex interactions among functional subnetworks is crucial for the diagnosis of mental disorders and the identification of functional pathways. However, learning the interactions of the underlying subnetworks remains a significant challenge for existing Transformer-based methods due to the limited number of training samples. To address these challenges, we propose KD-Brain, a Prior-Informed Graph Learning framework for explicitly encoding prior knowledge to guide the learning process. Specifically, we design a Semantic-Conditioned Interaction mechanism that injects semantic priors into the attention query, explicitly navigating the subnetwork interactions based on their functional identities. Furthermore, we introduce a Pathology-Consistent Constraint, which regularizes the model optimization by aligning the learned interaction distributions with clinical priors. Additionally, KD-Brain leads to state-of-the-art performance on a wide range of disorder diagnosis tasks and identifies interpretable biomarkers consistent with psychiatric pathophysiology. Our code is available at https://anonymous.4open.science/r/KDBrain.

cs.LG↗

arXiv2026

TLXML: Task-Level Explanation of Meta-Learning via Influence Functions

Meta-learning enables models to rapidly adapt to new tasks by leveraging prior experience, but its adaptation mechanisms remain opaque, especially regarding how past training tasks influence future predictions. We introduce TLXML (Task-Level eXplanation of Meta-Learning), a novel framework that extends influence functions to meta-learning settings and provides task-level explanations of adaptation and inference. By reformulating influence functions for the bi-level structure of meta-learning, we quantify the contribution of each meta-training task to the adapted model's behaviour. To ensure scalability, we propose a Gauss-Newton-based approximation that significantly reduces computational complexity from $O(pq^2)$ to $O(pq)$, where $p$ and $q$ denote the numbers of model and meta parameters, respectively. Moreover, we propose generalized influence functions defined using pseudo-inverse Hessian, which are applicable even when the loss landscape has flat directions. Results demonstrate that TLXML effectively ranks training tasks by their influence on downstream performance, offering concise, intuitive explanations aligned with user-level abstraction. This work provides a critical step toward interpretable and trustworthy meta-learning systems.

cs.LG↗

arXiv2026

Memory Is Communication: The Frontier Between Remembering and Signaling

A bounded agent may obtain information for a decision from its own past, from peers, or from both sources. Retaining task-relevant history can reduce later communication, while a peer message can supply what memory lacks. Under limits on both resources, how should an agent allocate its information budget? Given a fixed task and decision rule, the memory and message rate pairs attaining a performance threshold form an achievable region under specified rules for using history and peer observations. We call its efficient boundary the remembering--signaling frontier. Across conditions where history permits the same maximum reduction in task loss, we hypothesize that a bounded agent will need less peer communication when it obtains a larger loss reduction from history. In preliminary referential games, target repetition coincided with shorter successful messages, while predictability from a hidden cyclic rule did not shorten them. Experiments varying memory and message rates can estimate the frontier and test this prediction across cooperative tasks.

cs.AI↗

arXiv2026

Toward Personal Intelligence Through Cooperative Observation

A personal AI system needs a model of the user's goals, constraints, and ongoing commitments to plan and act on their behalf, and the quality of that model is bounded by what the system can observe. Broader observation does not by itself improve assistance because a bounded system must select and compress information for the task at hand. We argue that this observation bottleneck has a cooperative structure: the system builds a partial model of the user's changing life, the user evaluates its actions, and the user's consent and control shape what it can observe next. Useful and inspectable behavior can give users a reason to maintain or expand the observation channel, while failures can lead them to correct, narrow, revoke, or abandon it. We use the term cooperative observation for this feedback loop among usefulness, trust, and future access, and propose it as a framework for personal intelligence. We report a preliminary single-subject account from Organizm, a prototype used over six months, and outline evaluation directions for measuring how observation quality shapes personal AI.

cs.AI↗

arXiv2026

Why Solve It Twice? Hierarchical Accumulation of Skills for Transfer-Efficient ML Engineering

ML engineering agents waste compute rediscovering known techniques because every competition is a cold start. We present HASTE, a hierarchical multi-agent system that organizes cross-competition knowledge into three scope tiers (global, domain, and competition-specific), each coupled to a matching agent level. An orchestrator coordinates domain specialists and promotes learning between tiers via LLM-driven abstraction. A controlled ablation provides evidence for scoped loading: holding a 159-skill inventory constant across 8 competitions, tiered loading achieves a 100% medal rate while flat loading reaches only 62.5%, the same medal rate as loading no skills, and consumes 2x the output tokens. On the full MLE-Bench Lite benchmark (22 Kaggle competitions), HASTE reaches a medal rate of 77.3% using Claude Sonnet 4.6 at 12h per competition; this is a single-seed campaign result, and multi-seed replication is the priority follow-up. In a cold-start run, the system begins with no accumulated skills. In warm-start runs, it reloads skills learned from earlier competitions, using only global and domain-level skills for transfer across competitions. Warm starts use 52% fewer refinement iterations, and the fraction of proposed changes kept by the agent rises from 42% at low inventory to 85% once 50+ skills are available. These results suggest that better knowledge organization can partly substitute for model strength and compute budget in ML-engineering agents.

cs.AI↗

arXiv2026

From Signals to Structure: How Memory Architecture Drives Language Emergence in LLM Agents

How do two agents invent a shared language from scratch? In a Lewis signaling game, a sender and receiver must coordinate on a code using only their interaction history. We study five memory architectures across varying channel configurations with LLM agents and find that memory architecture matters more than channel capacity. Agents with a persistent private notebook benefit from surplus channel capacity and avoid the high-capacity collapse seen in stateless agents, achieving the most reliable coordination ($0.867 \pm 0.023$ at capacity = 25). Stateless agents peak at moderate capacity and then degrade as the vocabulary grows beyond what a rolling context window can track The notebook externalizes learned conventions, freeing agents from having to re-derive codes each round. An information bottleneck-inspired argument predicts an optimal capacity equal to the number of objects. Instead, the bottleneck (capacity = 8) proves to be a fragility point, and surplus capacity is generally better. We show that channel capacity alone cannot predict coordination; memory architecture determines whether agents turn interaction history into stable conventions, and both dimensions are needed to understand how signals become language.

cs.AI↗

arXiv2026

Multiscale Structure-Guided Latent Diffusion for Multimodal MRI Translation

Although diffusion models have achieved remarkable progress in multi-modal magnetic resonance imaging (MRI) translation tasks, existing methods still tend to suffer from anatomical inconsistencies or degraded texture details when handling arbitrary missing-modality scenarios. To address these issues, we propose a latent diffusion-based multi-modal MRI translation framework, termed MSG-LDM. By leveraging the available modalities, the proposed method infers complete structural information, which preserves reliable boundary details. Specifically, we introduce a style--structure disentanglement mechanism in the latent space, which explicitly separates modality-specific style features from shared structural representations, and jointly models low-frequency anatomical layouts and high-frequency boundary details in a multi-scale feature space. During the structure disentanglement stage, high-frequency structural information is explicitly incorporated to enhance feature representations, guiding the model to focus on fine-grained structural cues while learning modality-invariant low-frequency anatomical representations. Furthermore, to reduce interference from modality-specific styles and improve the stability of structure representations, we design a style consistency loss and a structure-aware loss. Extensive experiments on the BraTS2020 and WMH datasets demonstrate that the proposed method outperforms existing MRI synthesis approaches, particularly in reconstructing complete structures. The source code is publicly available at https://github.com/ziyi-start/MSG-LDM.

eess.IV↗

arXiv2026

IDRL: An Individual-Aware Multimodal Depression-Related Representation Learning Framework for Depression Diagnosis

Depression is a severe mental disorder, and reliable identification plays a critical role in early intervention and treatment. Multimodal depression detection aims to improve diagnostic performance by jointly modeling complementary information from multiple modalities. Recently, numerous multimodal learning approaches have been proposed for depression analysis; however, these methods suffer from the following limitations: 1) inter-modal inconsistency and depression-unrelated interference, where depression-related cues may conflict across modalities while substantial irrelevant content obscures critical depressive signals, and 2) diverse individual depressive presentations, leading to individual differences in modality and cue importance that hinder reliable fusion. To address these issues, we propose Individual-aware Multimodal Depression-related Representation Learning Framework (IDRL) for robust depression diagnosis. Specifically, IDRL 1) disentangles multimodal representations into a modality-common depression space, a modality-specific depression space, and a depression-unrelated space to enhance modality alignment while suppressing irrelevant information, and 2) introduces an individual-aware modality-fusion module (IAF) that dynamically adjusts the weights of disentangled depression-related features based on their predictive significance, thereby achieving adaptive cross-modal fusion for different individuals. Extensive experiments demonstrate that IDRL achieves superior and robust performance for multimodal depression detection.

cs.CV↗

arXiv2026

Visually-Guided Controllable Medical Image Generation via Fine-Grained Semantic Disentanglement

Medical image synthesis is crucial for alleviating data scarcity and privacy constraints. However, fine-tuning general text-to-image (T2I) models remains challenging, mainly due to the significant modality gap between complex visual details and abstract clinical text. In addition, semantic entanglement persists, where coarse-grained text embeddings blur the boundary between anatomical structures and imaging styles, thus weakening controllability during generation. To address this, we propose a Visually-Guided Text Disentanglement framework. We introduce a cross-modal latent alignment mechanism that leverages visual priors to explicitly disentangle unstructured text into independent semantic representations. Subsequently, a Hybrid Feature Fusion Module (HFFM) injects these features into a Diffusion Transformer (DiT) through separated channels, enabling fine-grained structural control. Experimental results in three datasets demonstrate that our method outperforms existing approaches in terms of generation quality and significantly improves performance on downstream classification tasks. The source code is available at https://github.com/hx111/VG-MedGen.

cs.CV↗

arXiv2026

BrainSCL: Subtype-Guided Contrastive Learning for Brain Disorder Diagnosis

Mental disorder populations exhibit pronounced heterogeneity -- that is, the significant differences between samples -- poses a significant challenge to the definition of positive pairs in contrastive learning. To address this, we propose a subtype-guided contrastive learning framework that models patient heterogeneity as latent subtypes and incorporates them as structural priors to guide discriminative representation learning. Specifically, we construct multi-view representations by combining patients' clinical text with graph structure adaptively learned from BOLD signals, to uncover latent subtypes via unsupervised spectral clustering. A dual-level attention mechanism is proposed to construct prototypes for capturing stable subtype-specific connectivity patterns. We further propose a subtype-guided contrastive learning strategy that pulls samples toward their subtype prototype graph, reinforcing intra-subtype consistency for providing effective supervisory signals to improve model performance. We evaluate our method on Major Depressive Disorder (MDD), Bipolar Disorder (BD), and Autism Spectrum Disorders (ASD). Experimental results confirm the effectiveness of subtype prototype graphs in guiding contrastive learning and demonstrate that the proposed approach outperforms state-of-the-art approaches. Our code is available at https://anonymous.4open.science/r/BrainSCL-06D7.

cs.LG↗

arXiv2026

Learning the Hierarchical Organization in Brain Network for Brain Disorder Diagnosis

Brain network analysis based on functional Magnetic Resonance Imaging (fMRI) is pivotal for diagnosing brain disorders. Existing approaches typically rely on predefined functional sub-networks to construct sub-network associations. However, we identified many cross-network interaction patterns with high Pearson correlations that this strict, prior-based organization fails to capture. To overcome this limitation, we propose the Brain Hierarchical Organization Learning (BrainHO) to learn inherently hierarchical brain network dependencies based on their intrinsic features rather than predefined sub-network labels. Specifically, we design a hierarchical attention mechanism that allows the model to aggregate nodes into a hierarchical organization, effectively capturing intricate connectivity patterns at the subgraph level. To ensure diverse, complementary, and stable organizations, we incorporate an orthogonality constraint loss, alongside a hierarchical consistency constraint strategy, to refine node-level features using high-level graph semantics. Extensive experiments on the publicly available ABIDE and REST-meta-MDD datasets demonstrate that BrainHO not only achieves state-of-the-art classification performance but also uncovers interpretable, clinically significant biomarkers by precisely localizing disease-related sub-networks.

cs.LG↗

arXiv2026

BrainSTR: Spatio-Temporal Contrastive Learning for Interpretable Dynamic Brain Network Modeling

Dynamic functional connectivity captures time-varying brain states for better neuropsychiatric diagnosis and spatio-temporal interpretability, i.e., identifying when discriminative disease signatures emerge and where they reside in the connectivity topology. Reliable interpretability faces major challenges: diagnostic signals are often subtle and sparsely distributed across both time and topology, while nuisance fluctuations and non-diagnostic connectivities are pervasive. To address these issues, we propose BrainSTR, a spatio-temporal contrastive learning framework for interpretable dynamic brain network modeling. BrainSTR learns state-consistent phase boundaries via a data-driven Adaptive Phase Partition module, identifies diagnostically critical phases with attention, and extracts disease-related connectivity within each phase using an Incremental Graph Structure Generator regularized by binarization, temporal smoothness, and sparsity. Then, we introduce a spatio-temporal supervised contrastive learning approach that leverages diagnosis-relevant spatio-temporal patterns to refine the similarity metric between samples and capture more discriminative spatio-temporal features, thereby constructing a well-structured semantic space for coherent and interpretable representations. Experiments on ASD, BD, and MDD validate the effectiveness of BrainSTR, and the discovered critical phases and subnetworks provide interpretable evidence consistent with prior neuroimaging findings. Our code: https://anonymous.4open.science/r/BrainSTR1.

cs.CV↗

arXiv2025

Style Content Decomposition-based Data Augmentation for Domain Generalizable Medical Image Segmentation

Due to domain shifts across diverse medical imaging modalities, learned segmentation models often suffer significant performance degradation during deployment. We posit that these domain shifts can generally be categorized into two main components: 1) "style" shifts, referring to global disparities in image properties such as illumination, contrast, and color; and 2) "content" shifts, which involve local discrepancies in anatomical structures. To address the domain shifts in medical image segmentation, we first factorize an image into style codes and content maps, explicitly modeling the "style" and "content" components. Building on this, we introduce a Style-Content decomposition-based data augmentation algorithm (StyCona), which performs augmentation on both the global style and local content of source-domain images, enabling the training of a well-generalized model for domain generalizable medical image segmentation. StyCona is a simple yet effective plug-and-play module that substantially improves model generalization without requiring additional training parameters or modifications to segmentation model architectures. Experiments on cardiac magnetic resonance imaging and fundus photography segmentation tasks, with single and multiple target domains respectively, demonstrate the effectiveness of StyCona and its superiority over state-of-the-art domain generalization methods. The code is available at https://github.com/Senyh/StyCona.

eess.IV↗

arXiv2025

Evaluating Sound Similarity Metrics for Differentiable, Iterative Sound-Matching

Manual sound design with a synthesizer is inherently iterative: an artist compares the synthesized output to a mental target, adjusts parameters, and repeats until satisfied. Iterative sound-matching automates this workflow by continually programming a synthesizer under the guidance of a loss function (or similarity measure) toward a target sound. Prior comparisons of loss functions have typically favored one metric over another, but only within narrow settings: limited synthesis methods, few loss types, often without blind listening tests. This leaves open the question of whether a universally optimal loss exists, or the choice of loss remains a creative decision conditioned on the synthesis method and the sound designer's preference. We propose differentiable iterative sound-matching as the natural extension of the available literature, since it combines the manual approach to sound design with modern advances in machine learning. To analyze the variability of loss function performance across synthesizers, we implemented a mix of four novel and established differentiable loss functions, and paired them with differentiable subtractive, additive, and AM synthesizers. For each of the sixteen synthesizer--loss combinations, we ran 300 randomized sound-matching trials. Performance was measured using parameter differences, spectrogram-distance metrics, and manually assigned listening scores. We observed a moderate level of consistency among the three performance measures. Our post-hoc analysis shows that the loss function performance is highly dependent on the synthesizer. These findings underscore the value of expanding the scope of sound-matching experiments and developing new similarity metrics tailored to specific synthesis techniques rather than pursuing one-size-fits-all solutions.

cs.SD↗

arXiv2025

SynMatch: Rethinking Consistency in Medical Image Segmentation with Sparse Annotations

Label scarcity remains a major challenge in deep learning-based medical image segmentation. Recent studies use strong-weak pseudo supervision to leverage unlabeled data. However, performance is often hindered by inconsistencies between pseudo labels and their corresponding unlabeled images. In this work, we propose \textbf{SynMatch}, a novel framework that sidesteps the need for improving pseudo labels by synthesizing images to match them instead. Specifically, SynMatch synthesizes images using texture and shape features extracted from the same segmentation model that generates the corresponding pseudo labels for unlabeled images. This design enables the generation of highly consistent synthesized-image-pseudo-label pairs without requiring any training parameters for image synthesis. We extensively evaluate SynMatch across diverse medical image segmentation tasks under semi-supervised learning (SSL), weakly-supervised learning (WSL), and barely-supervised learning (BSL) settings with increasingly limited annotations. The results demonstrate that SynMatch achieves superior performance, especially in the most challenging BSL setting. For example, it outperforms the recent strong-weak pseudo supervision-based method by 29.71\% and 10.05\% on the polyp segmentation task with 5\% and 10\% scribble annotations, respectively. The code will be released at https://github.com/Senyh/SynMatch.

cs.CV↗

arXiv2025

ConStyX: Content Style Augmentation for Generalizable Medical Image Segmentation

Medical images are usually collected from multiple domains, leading to domain shifts that impair the performance of medical image segmentation models. Domain Generalization (DG) aims to address this issue by training a robust model with strong generalizability. Recently, numerous domain randomization-based DG methods have been proposed. However, these methods suffer from the following limitations: 1) constrained efficiency of domain randomization due to their exclusive dependence on image style perturbation, and 2) neglect of the adverse effects of over-augmented images on model training. To address these issues, we propose a novel domain randomization-based DG method, called content style augmentation (ConStyX), for generalizable medical image segmentation. Specifically, ConStyX 1) augments the content and style of training data, allowing the augmented training data to better cover a wider range of data domains, and 2) leverages well-augmented features while mitigating the negative effects of over-augmented features during model training. Extensive experiments across multiple domains demonstrate that our ConStyX achieves superior generalization performance. The code is available at https://github.com/jwxsp1/ConStyX.

eess.IV↗

arXiv2025

Adaptive Mix for Semi-Supervised Medical Image Segmentation

Mix-up is a key technique for consistency regularization-based semi-supervised learning methods, blending two or more images to generate strong-perturbed samples for strong-weak pseudo supervision. Existing mix-up operations are performed either randomly or with predefined fixed rules, such as replacing low-confidence patches with high-confidence ones. The former lacks control over the perturbation degree, leading to overfitting on randomly perturbed samples, while the latter tends to generate images with trivial perturbations, both of which limit the effectiveness of consistency regularization. This paper aims to answer the following question: How can image mix-up perturbation be adaptively performed during training? To this end, we propose an Adaptive Mix algorithm (AdaMix) for image mix-up in a self-paced learning manner. Given that, in general, a model's performance gradually improves during training, AdaMix is equipped with a self-paced curriculum that, in the initial training stage, provides relatively simple perturbed samples and then gradually increases the difficulty of perturbed images by adaptively controlling the perturbation degree based on the model's learning state estimated by a self-paced regularize. We develop three frameworks with our AdaMix, i.e., AdaMix-ST, AdaMix-MT, and AdaMix-CT, for semi-supervised medical image segmentation. Extensive experiments on three public datasets show that the proposed frameworks can achieve superior performance. For example, compared with the state-of-the-art, AdaMix-CT achieves relative improvements of 2.62% in Dice similarity coefficient and 48.25% in average surface distance on the ACDC dataset with 10% labeled data. The results demonstrate that mix-up operations with dynamically adjusted perturbation strength based on the segmentation model's state can significantly enhance the effectiveness of consistency regularization.

cs.CV↗

arXiv2025

FundusGAN: A Hierarchical Feature-Aware Generative Framework for High-Fidelity Fundus Image Generation

Recent advancements in ophthalmology foundation models such as RetFound have demonstrated remarkable diagnostic capabilities but require massive datasets for effective pre-training, creating significant barriers for development and deployment. To address this critical challenge, we propose FundusGAN, a novel hierarchical feature-aware generative framework specifically designed for high-fidelity fundus image synthesis. Our approach leverages a Feature Pyramid Network within its encoder to comprehensively extract multi-scale information, capturing both large anatomical structures and subtle pathological features. The framework incorporates a modified StyleGAN-based generator with dilated convolutions and strategic upsampling adjustments to preserve critical retinal structures while enhancing pathological detail representation. Comprehensive evaluations on the DDR, DRIVE, and IDRiD datasets demonstrate that FundusGAN consistently outperforms state-of-the-art methods across multiple metrics (SSIM: 0.8863, FID: 54.2, KID: 0.0436 on DDR). Furthermore, disease classification experiments reveal that augmenting training data with FundusGAN-generated images significantly improves diagnostic accuracy across multiple CNN architectures (up to 6.49\% improvement with ResNet50). These results establish FundusGAN as a valuable foundation model component that effectively addresses data scarcity challenges in ophthalmological AI research, enabling more robust and generalizable diagnostic systems while reducing dependency on large-scale clinical data collection.

eess.IV↗