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Pamela P. Martinez

Publications and source records attributed to Pamela P. Martinez.

2 recordsLinked to original sources

Incorporating Authority Perception, Economic Status, and Behavioral Response in Infectious Disease Control

We introduce a multi-population mean field game framework to examine how economic status and authority perception shape vaccination and social distancing decisions under different epidemic control policies. We carried out a survey to inform our model and stratify the population into six groups based on income and perception of authority, capturing behavioral heterogeneity. Individuals adjust their socialization and vaccination levels to optimize objectives such as minimizing treatment costs, complying with social-distancing guidelines if they are authority-followers, or reducing losses from decreased social interactions if they are authority-indifferents, alongside economic costs. Public health authorities influence behavior through social-distancing guidelines and vaccination costs. We characterize the Nash equilibrium via a forward-backward differential equation system, provide its mathematical analysis, and develop a numerical algorithm to solve it. Our findings reveal a trade-off between social-distancing and vaccination decisions. Under stricter guidelines that target both susceptible and infected individuals, followers reduce both socialization and vaccination levels, while indifferents increase socialization due to followers' preventative measures. Adaptive guidelines targeting infected individuals effectively reduce infections and narrow the gap between low- and high-income groups, even when susceptible individuals socialize more and vaccinate less. Lower vaccination costs incentivize vaccination among low-income groups, but their impact on disease spread is smaller than when they are coupled with social-distancing guidelines. Trust-building emerges as a critical factor in epidemic mitigation, underscoring the importance of data-informed, game-theoretical models that aim to understand complex human responses to mitigation policies.

math.OC↗

Cholera forecast for Dhaka, Bangladesh, with the 2016 El Niño

A substantial body of work supports a teleconnection between the El Niño Southern Oscillation (ENSO) and cholera incidence in Bangladesh. In particular, high positive anomalies during the winter (Dec-Feb) in Sea Surface Temperatures (SST) in the Tropical Pacific have been shown to exacerbate the seasonal outbreak of cholera following the monsoons from Aug to Nov, and climate studies have indicated a role of regional precipitation over Bangladesh in mediating this long-distance effect. Thus, the current strong El Niño has the potential to significantly increase cholera risk this year in Dhaka, Bangladesh, where the last five years have experienced low seasons of the disease. To examine this possibility and produce a forecast for the city, we considered two models for the transmission dynamics of cholera: a statistical model previously developed for the disease in this region, and a process-based model presented here that includes the effect of SST anomalies in the force of infection and is fitted to extensive cholera surveillance record between 1995 and 2010. Prediction accuracy was evaluated with 'out-of-fit' data from the same surveillance efforts, by comparing the total number of cholera cases observed for the season to those predicted by model simulations 8 to 12 months ahead, starting in January each year. Encouraged by accurate forecasts for the low risk of cholera for this period, we then generated a prediction for this coming season. An increase above the third quantile in cholera cases is expected for the period of Aug - Dec 2016 with 92% and 87% probability respectively for the two models. This alert warrants the preparedness of the public health system. We discuss the possible limitations of our approach, including variations in the impact of El Niño events, and the importance of this large, warm event for further informing an early-warning system for cholera in Dhaka

q-bio.PE↗