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Pan Zhao

Publications and source records attributed to Pan Zhao.

At least 19 recordsLinked to original sources

Efficient estimation of cumulative incidence curves via data fusion with surrogates: application to integrated analysis of vaccine trial and immunobridging data

Refined vaccine regimens containing variant-matched inserts are often authorized based on historical phase 3 efficacy trials together with immunobridging studies. Phase 3 trials are essential for establishing immune biomarkers that reliably predict disease risk or vaccine efficacy against clinical endpoints. Once such immune correlates are identified, updated vaccine regimens can be approved through immunobridging designs that compare the immunogenicity of the updated regimen to that of an already-approved vaccine. We develop methods of inference for the counterfactual cumulative incidence curve using participant-level data from both a historical vaccine efficacy trial and an immunobridging study. We further extend these methods to pathogens with multiple serotypes -- such as dengue virus and influenza -- by estimating cause-specific cumulative incidence curves. We describe the identification assumptions, propose efficient and multiply robust estimators, and assess their finite-sample performance through simulation studies. We then apply the proposed methods to (1) estimating the hypothetical cumulative incidence curve for a bivalent mRNA booster and (2) testing a key assumption of no controlled direct effects, using data from the COVID-19 Variant Immunologic Landscape (COVAIL) Trial, a multistage randomized clinical study evaluating the safety and immunogenicity of a second COVID-19 booster dose.

stat.ME

TurboAgent: An LLM-Driven Autonomous Multi-Agent Framework for Turbomachinery Aerodynamic Design

The aerodynamic design of turbomachinery is a complex and tightly coupled multi-stage process involving geometry generation, performance prediction, optimization, and high-fidelity physical validation. Existing intelligent design approaches typically focus on individual stages or rely on loosely coupled pipelines, making fully autonomous end-to-end design challenging. To address this issue, this study proposes TurboAgent, a large language model (LLM)-driven autonomous multi-agent framework for turbomachinery aerodynamic design and optimization. The LLM serves as the core for task planning and coordination, while specialized agents handle generative design, rapid performance prediction, multi-objective optimization, and physics-based validation. The framework transforms traditional trial-and-error design into a data-driven collaborative workflow, with high-fidelity simulations retained for final verification. A transonic single-rotor compressor is used for validation. The results show strong agreement between target performance, generated designs, and CFD simulations. The coefficients of determination for mass flow rate, total pressure ratio, and isentropic efficiency all exceed 0.91, with normalized RMSE values below 8%. The optimization agent further improves isentropic efficiency by 1.61% and total pressure ratio by 3.02%. The complete workflow can be executed within approximately 30 minutes under parallel computing. These results demonstrate that TurboAgent enables an autonomous closed-loop design process from natural language requirements to final design generation, providing an efficient and scalable paradigm for turbomachinery aerodynamic design.

cs.AI

Improving INDI for Input Nonaffine Systems via Learning-Based Nonlinear Control Allocation

This paper first demonstrates that applying standard incremental nonlinear dynamic inversion (INDI) with incremental control allocation (ICA) to input nonaffine systems relies on an untenable linear approximation of the actuator model. It then shows that avoiding this issue, while retaining the static control allocation paradigm, generally requires solving a nonlinear programming (NLP) problem. To address the associated online computational challenges, the paper subsequently presents a supervised learning-based approach. Numerical experiments on an example problem validate the identified limitations of standard INDI + ICA for input nonaffine systems, while also demonstrating that the proposed learning-based method provides an effective and computationally tractable alternative.

eess.SY

DUGAE: Unified Geometry and Attribute Enhancement via Spatiotemporal Correlations for G-PCC Compressed Dynamic Point Clouds

Existing post-decoding quality enhancement methods for point clouds are designed for static data and typically process each frame independently. As a result, they cannot effectively exploit the spatiotemporal correlations present in point cloud sequences.We propose a unified geometry and attribute enhancement framework (DUGAE) for G-PCC compressed dynamic point clouds that explicitly exploits inter-frame spatiotemporal correlations in both geometry and attributes. First, a dynamic geometry enhancement network (DGE-Net) based on sparse convolution (SPConv) and feature-domain geometry motion compensation (GMC) aligns and aggregates spatiotemporal information. Then, a detail-aware k-nearest neighbors (DA-KNN) recoloring module maps the original attributes onto the enhanced geometry at the encoder side, improving mapping completeness and preserving attribute details. Finally, a dynamic attribute enhancement network (DAE-Net) with dedicated temporal feature extraction and feature-domain attribute motion compensation (AMC) refines attributes by modeling complex spatiotemporal correlations. On seven dynamic point clouds from the 8iVFB v2, Owlii, and MVUB datasets, DUGAE significantly enhanced the performance of the latest G-PCC geometry-based solid content test model (GeS-TM v10). For geometry (D1), it achieved an average BD-PSNR gain of 11.03 dB and a 93.95% BD-bitrate reduction. For the luma component, it achieved a 4.23 dB BD-PSNR gain with a 66.61% BD-bitrate reduction. DUGAE also improved perceptual quality (as measured by PCQM) and outperformed V-PCC. Our source code will be released on GitHub at: https://github.com/yuanhui0325/DUGAE

cs.CV

Neural-NPV Control: Learning Parameter-Dependent Controllers and Lyapunov Functions

This paper presents Neural-NPV Control, a learning-based framework for joint synthesis of a parameter-dependent (PD) controller and a PD Lyapunov function using neural networks for an NPV system under input constraints. At the first stage, the proposed framework utilizes a gradient-based counterexample-guided procedure to synthesize a PD controller and a PD Lyapunov function candidate. The second stage relies on a level-set guided procedure to refine the controller and Lyapunov function candidate while maximizing the robust region of attraction (R-ROA). The learned controller, Lyapunov function, and R-ROA are empirically evaluated. We demonstrate the advantages of Neural-NPV over SOS-based methods in terms of applicability, performance, and scalability through numerical experiments involving a simple inverted pendulum with one scheduling parameter and a quadrotor system with three scheduling parameters.

eess.SY

Point Cloud Feature Coding for Object Detection over an Error-Prone Cloud-Edge Collaborative System

Cloud-edge collaboration enhances machine perception by combining the strengths of edge and cloud computing. Edge devices capture raw data (e.g., 3D point clouds) and extract salient features, which are sent to the cloud for deeper analysis and data fusion. However, efficiently and reliably transmitting features between cloud and edge devices remains a challenging problem. We focus on point cloud-based object detection and propose a task-driven point cloud compression and reliable transmission framework based on source and channel coding. To meet the low-latency and low-power requirements of edge devices, we design a lightweight yet effective feature compaction module that compresses the deepest feature among multi-scale representations by removing task-irrelevant regions and applying channel-wise dimensionality reduction to task-relevant areas. Then, a signal-to-noise ratio (SNR)-adaptive channel encoder dynamically encodes the attribute information of the compacted features, while a Low-Density Parity-Check (LDPC) encoder ensures reliable transmission of geometric information. At the cloud side, an SNR-adaptive channel decoder guides the decoding of attribute information, and the LDPC decoder corrects geometry errors. Finally, a feature decompaction module restores the channel-wise dimensionality, and a diffusion-based feature upsampling module reconstructs shallow-layer features, enabling multi-scale feature reconstruction. On the KITTI dataset, our method achieved a 172-fold reduction in feature size with 3D average precision scores of 93.17%, 86.96%, and 77.25% for easy, moderate, and hard objects, respectively, over a 0 dB SNR wireless channel. Our source code will be released on GitHub at: https://github.com/yuanhui0325/T-PCFC.

eess.IV

Robust Adaptive MPC in the Presence of Nonlinear Time-Varying Uncertainties: An Uncertainty Compensation Approach

This paper introduces an uncertainty compensation-based robust adaptive model predictive control (MPC) framework for linear systems with nonlinear time-varying uncertainties. The framework integrates an L1 adaptive controller to compensate for the matched uncertainty and a robust feedback controller, designed using linear matrix inequalities, to mitigate the effect of unmatched uncertainty on target output channels. Uniform bounds on the errors between the system's states and control inputs and those of a nominal (i.e., uncertainty-free) system are derived. These error bounds are then used to tighten the actual system's state and input constraints, enabling the design of an MPC for the nominal system under these tightened constraints. Referred to as uncertainty compensation-based MPC (UC-MPC), this approach ensures constraint satisfaction while delivering enhanced performance compared to existing methods. Simulation results for a flight control example and a spacecraft landing on an asteroid demonstrate the effectiveness of the proposed framework.

eess.SY

UGAE: Unified Geometry and Attribute Enhancement for G-PCC Compressed Point Clouds

Lossy compression of point clouds reduces storage and transmission costs; however, it inevitably leads to irreversible distortion in geometry structure and attribute information. To address these issues, we propose a unified geometry and attribute enhancement (UGAE) framework, which consists of three core components: post-geometry enhancement (PoGE), pre-attribute enhancement (PAE), and post-attribute enhancement (PoAE). In PoGE, a Transformer-based sparse convolutional U-Net is used to reconstruct the geometry structure with high precision by predicting voxel occupancy probabilities. Building on the refined geometry structure, PAE introduces an innovative enhanced geometry-guided recoloring strategy, which uses a detail-aware K-Nearest Neighbors (DA-KNN) method to achieve accurate recoloring and effectively preserve high-frequency details before attribute compression. Finally, at the decoder side, PoAE uses an attribute residual prediction network with a weighted mean squared error (W-MSE) loss to enhance the quality of high-frequency regions while maintaining the fidelity of low-frequency regions. UGAE significantly outperformed existing methods on three benchmark datasets: 8iVFB, Owlii, and MVUB. Compared to the latest G-PCC test model (TMC13v29), UGAE achieved an average BD-PSNR gain of 9.98 dB and 90.98% BD-bitrate savings for geometry under the D1 metric, as well as a 3.67 dB BD-PSNR improvement with 56.88% BD-bitrate savings for attributes on the Y component. Additionally, it improved perceptual quality significantly.

cs.CV

Teacher Motion Priors: Enhancing Robot Locomotion over Challenging Terrain

Achieving robust locomotion on complex terrains remains a challenge due to high dimensional control and environmental uncertainties. This paper introduces a teacher prior framework based on the teacher student paradigm, integrating imitation and auxiliary task learning to improve learning efficiency and generalization. Unlike traditional paradigms that strongly rely on encoder-based state embeddings, our framework decouples the network design, simplifying the policy network and deployment. A high performance teacher policy is first trained using privileged information to acquire generalizable motion skills. The teacher's motion distribution is transferred to the student policy, which relies only on noisy proprioceptive data, via a generative adversarial mechanism to mitigate performance degradation caused by distributional shifts. Additionally, auxiliary task learning enhances the student policy's feature representation, speeding up convergence and improving adaptability to varying terrains. The framework is validated on a humanoid robot, showing a great improvement in locomotion stability on dynamic terrains and significant reductions in development costs. This work provides a practical solution for deploying robust locomotion strategies in humanoid robots.

cs.RO

Parameter-Dependent Control Lyapunov Functions for Stabilizing Nonlinear Parameter-Varying Systems

This paper introduces the concept of parameter-dependent (PD) control Lyapunov functions (CLFs) for gain-scheduled stabilization of nonlinear parameter-varying (NPV) systems. It shows that given a PD-CLF, a min-norm control law can be constructed by solving a robust quadratic program. For polynomial control-affine NPV systems, it provides convex conditions, based on the sum of squares programming, to jointly synthesize a PD-CLF and a PD controller while maximizing the PD region of stabilization. Input constraints can be straightforwardly incorporated into the synthesis procedure. Unlike traditional linear parameter-varying (LPV) methods that rely on linearization or over-approximation to get an LPV model, the proposed framework fully captures the nonlinearities of the system dynamics. The theoretical results are validated through numerical simulations, including a 2D rocket landing case study under varying mass and inertia.

math.OC

CROPS: A Deployable Crop Management System Over All Possible State Availabilities

Exploring the optimal management strategy for nitrogen and irrigation has a significant impact on crop yield, economic profit, and the environment. To tackle this optimization challenge, this paper introduces a deployable \textbf{CR}op Management system \textbf{O}ver all \textbf{P}ossible \textbf{S}tate availabilities (CROPS). CROPS employs a language model (LM) as a reinforcement learning (RL) agent to explore optimal management strategies within the Decision Support System for Agrotechnology Transfer (DSSAT) crop simulations. A distinguishing feature of this system is that the states used for decision-making are partially observed through random masking. Consequently, the RL agent is tasked with two primary objectives: optimizing management policies and inferring masked states. This approach significantly enhances the RL agent's robustness and adaptability across various real-world agricultural scenarios. Extensive experiments on maize crops in Florida, USA, and Zaragoza, Spain, validate the effectiveness of CROPS. Not only did CROPS achieve State-of-the-Art (SOTA) results across various evaluation metrics such as production, profit, and sustainability, but the trained management policies are also immediately deployable in over of ten millions of real-world contexts. Furthermore, the pre-trained policies possess a noise resilience property, which enables them to minimize potential sensor biases, ensuring robustness and generalizability. Finally, unlike previous methods, the strength of CROPS lies in its unified and elegant structure, which eliminates the need for pre-defined states or multi-stage training. These advancements highlight the potential of CROPS in revolutionizing agricultural practices.

cs.AI

The New Agronomists: Language Models are Experts in Crop Management

Crop management plays a crucial role in determining crop yield, economic profitability, and environmental sustainability. Despite the availability of management guidelines, optimizing these practices remains a complex and multifaceted challenge. In response, previous studies have explored using reinforcement learning with crop simulators, typically employing simple neural-network-based reinforcement learning (RL) agents. Building on this foundation, this paper introduces a more advanced intelligent crop management system. This system uniquely combines RL, a language model (LM), and crop simulations facilitated by the Decision Support System for Agrotechnology Transfer (DSSAT). We utilize deep RL, specifically a deep Q-network, to train management policies that process numerous state variables from the simulator as observations. A novel aspect of our approach is the conversion of these state variables into more informative language, facilitating the language model's capacity to understand states and explore optimal management practices. The empirical results reveal that the LM exhibits superior learning capabilities. Through simulation experiments with maize crops in Florida (US) and Zaragoza (Spain), the LM not only achieves state-of-the-art performance under various evaluation metrics but also demonstrates a remarkable improvement of over 49\% in economic profit, coupled with reduced environmental impact when compared to baseline methods. Our code is available at \url{https://github.com/jingwu6/LM_AG}.

cs.LG

A Semiparametric Instrumented Difference-in-Differences Approach to Policy Learning

Recently, there has been a surge in methodological development for the difference-in-differences (DiD) approach to evaluate causal effects. Standard methods in the literature rely on the parallel trends assumption to identify the average treatment effect on the treated. However, the parallel trends assumption may be violated in the presence of unmeasured confounding, and the average treatment effect on the treated may not be useful in learning a treatment assignment policy for the entire population. In this article, we propose a general instrumented DiD approach for learning the optimal treatment policy. Specifically, we establish identification results using a binary instrumental variable (IV) when the parallel trends assumption fails to hold. Additionally, we construct a Wald estimator, novel inverse probability weighting (IPW) estimators, and a class of semiparametric efficient and multiply robust estimators, with theoretical guarantees on consistency and asymptotic normality, even when relying on flexible machine learning algorithms for nuisance parameters estimation. Furthermore, we extend the instrumented DiD to the panel data setting. We evaluate our methods in extensive simulations and a real data application.

stat.ME

Positivity-free Policy Learning with Observational Data

Policy learning utilizing observational data is pivotal across various domains, with the objective of learning the optimal treatment assignment policy while adhering to specific constraints such as fairness, budget, and simplicity. This study introduces a novel positivity-free (stochastic) policy learning framework designed to address the challenges posed by the impracticality of the positivity assumption in real-world scenarios. This framework leverages incremental propensity score policies to adjust propensity score values instead of assigning fixed values to treatments. We characterize these incremental propensity score policies and establish identification conditions, employing semiparametric efficiency theory to propose efficient estimators capable of achieving rapid convergence rates, even when integrated with advanced machine learning algorithms. This paper provides a thorough exploration of the theoretical guarantees associated with policy learning and validates the proposed framework's finite-sample performance through comprehensive numerical experiments, ensuring the identification of causal effects from observational data is both robust and reliable.

stat.ME

Robust Adaptive MPC Using Uncertainty Compensation

This paper presents an uncertainty compensation-based robust adaptive model predictive control (MPC) framework for linear systems with both matched and unmatched nonlinear uncertainties subject to both state and input constraints. In particular, the proposed control framework leverages an L1 adaptive controller (L1AC) to compensate for the matched uncertainties and to provide guaranteed uniform bounds on the error between the states and control inputs of the actual system and those of a nominal i.e., uncertainty-free, system. The performance bounds provided by the L1AC are then used to tighten the state and control constraints of the actual system, and a model predictive controller is designed for the nominal system with the tightened constraints. The proposed control framework, which we denote as uncertainty compensation-based MPC (UC-MPC), guarantees constraint satisfaction and achieves improved performance compared with existing methods. Simulation results on a flight control example demonstrate the benefits of the proposed framework.

eess.SY

Learning Tube-Certified Control using Robust Contraction Metrics

Control design for general nonlinear robotic systems with guaranteed stability and/or safety in the presence of model uncertainties is a challenging problem. Recent efforts attempt to learn a controller and a certificate (e.g., a Lyapunov function or a contraction metric) jointly using neural networks (NNs), in which model uncertainties are generally ignored during the learning process. In this paper, for nonlinear systems subject to bounded disturbances, we present a framework for jointly learning a robust nonlinear controller and a contraction metric using a novel disturbance rejection objective that certifies a tube bound using NNs for user-specified variables (e.g. control inputs). The learned controller aims to minimize the effect of disturbances on the actual trajectories of state and/or input variables from their nominal counterparts while providing certificate tubes around nominal trajectories that are guaranteed to contain actual trajectories in the presence of disturbances. Experimental results demonstrate that our framework can generate tighter (smaller) tubes and a controller that is computationally efficient to implement.

eess.SY

Verification of $L_1$ Adaptive Control using Verse Library: A Case Study of Quadrotors

$L_1$ adaptive control ($L_1$AC) is a control design technique that can handle a broad class of system uncertainties and provide transient performance guarantees. In this work-in-progress abstract, we discuss how existing formal verification tools can be applied to check the performance of $L_1$AC systems. We show that the theoretical transient performance and robustness guarantees of an $L_1$ adaptive controller for an 18-dimensional quadrotor system can be verified using the recently developed Verse reachability analysis tool. We will further consider the performance verification of $L_1$AC on systems with learning-enabled components.

eess.SY

$\mathcal{L}_1$Quad: $\mathcal{L}_1$ Adaptive Augmentation of Geometric Control for Agile Quadrotors with Performance Guarantees

Quadrotors that can operate predictably in the presence of imperfect model knowledge and external disturbances are crucial in safety-critical applications. We present L1Quad, a control architecture that ensures uniformly bounded transient response of the quadrotor's uncertain dynamics on the special Euclidean group SE(3). By leveraging the geometric controller and the L1 adaptive controller, the L1Quad architecture provides a theoretically justified framework for the design and analysis of quadrotor's tracking controller in the presence of nonlinear (time- and state-dependent) uncertainties on both the translational and rotational dynamics. In addition, we validate the performance of the L1Quad architecture through extensive experiments for eleven types of uncertainties across various trajectories. The results demonstrate that the L1Quad can achieve consistently small tracking errors despite the uncertainties and disturbances and significantly outperforms existing state-of-the-art controllers.

eess.SY