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Patric Müller

Publications and source records attributed to Patric Müller.

7 recordsLinked to original sources

Automated tomographic assessment of structural defects of freeze-dried pharmaceuticals

The topology and surface characteristics of lyophilisates significantly impact the stability and reconstitutability of freeze-dried pharmaceuticals. Consequently, visual quality control of the product is imperative. However, this procedure is not only time-consuming and labor-intensive but also expensive and prone to errors. In this paper, we present an approach for fully automated, non-destructive inspection of freeze-dried pharmaceuticals, leveraging robotics, computed tomography, and machine learning.

cond-mat.soft

Model geometries of porous materials

We describe a method for modeling the geometry of porous materials. The approach enables the independent selection of crucial parameters, including porosity, pore size distribution, pore shape, and connectivity. Consequently, it can effectively model a wide range of porous systems. Due to the diverse and systematic variation possibilities, the method is suitable for developing and optimizing porous structures. The geometries can be exported as triangular meshes, facilitating their immediate use in numerical simulation and further digital processing. We showcase the method's capabilities by minimizing the foam structure's thermal conductivity through geometry optimization.

cond-mat.mtrl-sci

Soft particles reinforce robotic grippers: Robotic grippers based on granular jamming of soft particles

Granular jamming has been identified as a fundamental mechanism for the operation of robotic grippers. In this work, we show, that soft particles like expanded polystyrene beads lead to significantly larger gripping forces in comparison to rigid particles. In contradiction to naive expectation, the combination of jamming and elasticity gives rise to very different properties of the jammed phase, compared to hard-particle systems. This may be of interest also beyond the application in robotic grippers.

cond-mat.soft

Censored linear model in high dimensions

Censored data are quite common in statistics and have been studied in depth in the last years. In this paper we consider censored high-dimensional data. High-dimensional models are in some way more complex than their low-dimensional versions, therefore some different techniques are required. For the linear case appropriate estimators based on penalized regression, have been developed in the last years. In particular in sparse contexts the $l_1$-penalised regression (also known as LASSO) performs very well. Only few theoretical work was done in order to analyse censored linear models in a high-dimensional context. We therefore consider a high-dimensional censored linear model, where the response variable is left-censored. We propose a new estimator, which aims to work with high-dimensional linear censored data. Theoretical non-asymptotic oracle inequalities are derived.

math.ST

The partial linear model in high dimensions

Partial linear models have been widely used as flexible method for modelling linear components in conjunction with non-parametric ones. Despite the presence of the non-parametric part, the linear, parametric part can under certain conditions be estimated with parametric rate. In this paper, we consider a high-dimensional linear part. We show that it can be estimated with oracle rates, using the LASSO penalty for the linear part and a smoothness penalty for the nonparametric part.

math.ST

Quasi-Likelihood and/or Robust Estimation in High Dimensions

We consider the theory for the high-dimensional generalized linear model with the Lasso. After a short review on theoretical results in literature, we present an extension of the oracle results to the case of quasi-likelihood loss. We prove bounds for the prediction error and $\ell_1$-error. The results are derived under fourth moment conditions on the error distribution. The case of robust loss is also given. We moreover show that under an irrepresentable condition, the $\ell_1$-penalized quasi-likelihood estimator has no false positives.

math.ST