arXiv subjects

Peiwei Li

Publications and source records attributed to Peiwei Li.

2 recordsLinked to original sources

arXiv2025

TECM*: A Data-Driven Assessment to Reinforcement Learning Methods and Application to Heparin Treatment Strategy for Surgical Sepsis

Objective: Sepsis is a life-threatening condition caused by severe infection leading to acute organ dysfunction. This study proposes a data-driven metric and a continuous reward function to optimize personalized heparin therapy in surgical sepsis patients. Methods: Data from the MIMIC-IV v1.0 and eICU v2.0 databases were used for model development and evaluation. The training cohort consisted of abdominal surgery patients receiving unfractionated heparin (UFH) after postoperative sepsis onset. We introduce a new RL-based framework: converting the discrete SOFA score to a continuous cxSOFA for more nuanced state and reward functions; Second, defining "good" or "bad" strategies based on cxSOFA by a stepwise manner; Third, proposing a Treatment Effect Comparison Matrix (TECM), analogous to a confusion matrix for classification tasks, to evaluate the treatment strategies. We applied different RL algorithms, Q-Learning, DQN, DDQN, BCQ and CQL to optimize the treatment and comprehensively evaluated the framework. Results: Among the AI-derived strategies, the cxSOFA-CQL model achieved the best performance, reducing mortality from 1.83% to 0.74% with the average hospital stay from 11.11 to 9.42 days. TECM demonstrated consistent outcomes across models, highlighting robustness. Conclusion: The proposed RL framework enables interpretable and robust optimization of heparin therapy in surgical sepsis. Continuous cxSOFA scoring and TECM-based evaluation provide nuanced treatment assessment, showing promise for improving clinical outcomes and decision-support reliability.

cs.LG↗

arXiv2021

Voxel R-CNN: Towards High Performance Voxel-based 3D Object Detection

Recent advances on 3D object detection heavily rely on how the 3D data are represented, \emph{i.e.}, voxel-based or point-based representation. Many existing high performance 3D detectors are point-based because this structure can better retain precise point positions. Nevertheless, point-level features lead to high computation overheads due to unordered storage. In contrast, the voxel-based structure is better suited for feature extraction but often yields lower accuracy because the input data are divided into grids. In this paper, we take a slightly different viewpoint -- we find that precise positioning of raw points is not essential for high performance 3D object detection and that the coarse voxel granularity can also offer sufficient detection accuracy. Bearing this view in mind, we devise a simple but effective voxel-based framework, named Voxel R-CNN. By taking full advantage of voxel features in a two stage approach, our method achieves comparable detection accuracy with state-of-the-art point-based models, but at a fraction of the computation cost. Voxel R-CNN consists of a 3D backbone network, a 2D bird-eye-view (BEV) Region Proposal Network and a detect head. A voxel RoI pooling is devised to extract RoI features directly from voxel features for further refinement. Extensive experiments are conducted on the widely used KITTI Dataset and the more recent Waymo Open Dataset. Our results show that compared to existing voxel-based methods, Voxel R-CNN delivers a higher detection accuracy while maintaining a real-time frame processing rate, \emph{i.e}., at a speed of 25 FPS on an NVIDIA RTX 2080 Ti GPU. The code is available at \url{https://github.com/djiajunustc/Voxel-R-CNN}.

cs.CV↗