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Pengcheng Xu

Publications and source records attributed to Pengcheng Xu.

At least 37 records · Page 2Linked to original sources

Omni-QALAS: Optimized Multiparametric Imaging for Simultaneous T1, T2 and Myelin Water Mapping

Purpose: To improve the accuracy of multiparametric estimation, including myelin water fraction (MWF) quantification, and reduce scan time in 3D-QALAS by optimizing sequence parameters, using a self-supervised multilayer perceptron network. Methods: We jointly optimize flip angles, T2 preparation durations, and sequence gaps for T1 recovery using a self-supervised MLP trained to minimize a Cramer-Rao bound-based loss function, with explicit constraints on total scan time. The optimization targets white matter, gray matter, and myelin water tissues, and its performance was validated through simulation, phantom, and in vivo experiments. Results: Building on our previously proposed MWF-QALAS method for simultaneous MWF, T1, and T2 mapping, the optimized sequence reduces the number of readouts from six to five and achieves a scan time nearly one minute shorter, while also yielding higher T1 and T2 accuracy and improved MWF maps. This sequence enables simultaneous multiparametric quantification, including MWF, at 1 mm isotropic resolution within 3 minutes and 30 seconds. Conclusion: This study demonstrated that optimizing sequence parameters using a self-supervised MLP network improved T1, T2 and MWF estimation accuracy, while reducing scan time.

q-bio.QM↗

DynamicControl: Adaptive Condition Selection for Improved Text-to-Image Generation

To enhance the controllability of text-to-image diffusion models, current ControlNet-like models have explored various control signals to dictate image attributes. However, existing methods either handle conditions inefficiently or use a fixed number of conditions, which does not fully address the complexity of multiple conditions and their potential conflicts. This underscores the need for innovative approaches to manage multiple conditions effectively for more reliable and detailed image synthesis. To address this issue, we propose a novel framework, DynamicControl, which supports dynamic combinations of diverse control signals, allowing adaptive selection of different numbers and types of conditions. Our approach begins with a double-cycle controller that generates an initial real score sorting for all input conditions by leveraging pre-trained conditional generation models and discriminative models. This controller evaluates the similarity between extracted conditions and input conditions, as well as the pixel-level similarity with the source image. Then, we integrate a Multimodal Large Language Model (MLLM) to build an efficient condition evaluator. This evaluator optimizes the ordering of conditions based on the double-cycle controller's score ranking. Our method jointly optimizes MLLMs and diffusion models, utilizing MLLMs' reasoning capabilities to facilitate multi-condition text-to-image (T2I) tasks. The final sorted conditions are fed into a parallel multi-control adapter, which learns feature maps from dynamic visual conditions and integrates them to modulate ControlNet, thereby enhancing control over generated images. Through both quantitative and qualitative comparisons, DynamicControl demonstrates its superiority over existing methods in terms of controllability, generation quality and composability under various conditional controls.

cs.CV↗

Mainframe-Style Channel Controllers for Modern Disaggregated Memory Systems

Despite the promise of alleviating the main memory bottleneck, and the existence of commercial hardware implementations, techniques for Near-Data Processing have seen relatively little real-world deployment. The idea has received renewed interest with the appearance of disaggregated or "far" memory, for example in the use of CXL memory pools. However, we argue that the lack of a clear OS-centric abstraction of Near-Data Processing is a major barrier to adoption of the technology. Inspired by the channel controllers which interface the CPU to disk drives in mainframe systems, we propose memory channel controllers as a convenient, portable, and virtualizable abstraction of Near-Data Processing for modern disaggregated memory systems. In addition to providing a clean abstraction that enables OS integration while requiring no changes to CPU architecture, memory channel controllers incorporate another key innovation: they exploit the cache coherence provided by emerging interconnects to provide a much richer programming model, with more fine-grained interaction, than has been possible with existing designs.

cs.OS↗

Semantic-guided Representation Learning for Multi-Label Recognition

Multi-label Recognition (MLR) involves assigning multiple labels to each data instance in an image, offering advantages over single-label classification in complex scenarios. However, it faces the challenge of annotating all relevant categories, often leading to uncertain annotations, such as unseen or incomplete labels. Recent Vision and Language Pre-training (VLP) based methods have made significant progress in tackling zero-shot MLR tasks by leveraging rich vision-language correlations. However, the correlation between multi-label semantics has not been fully explored, and the learned visual features often lack essential semantic information. To overcome these limitations, we introduce a Semantic-guided Representation Learning approach (SigRL) that enables the model to learn effective visual and textual representations, thereby improving the downstream alignment of visual images and categories. Specifically, we first introduce a graph-based multi-label correlation module (GMC) to facilitate information exchange between labels, enriching the semantic representation across the multi-label texts. Next, we propose a Semantic Visual Feature Reconstruction module (SVFR) to enhance the semantic information in the visual representation by integrating the learned textual representation during reconstruction. Finally, we optimize the image-text matching capability of the VLP model using both local and global features to achieve zero-shot MLR. Comprehensive experiments are conducted on several MLR benchmarks, encompassing both zero-shot MLR (with unseen labels) and single positive multi-label learning (with limited labels), demonstrating the superior performance of our approach compared to state-of-the-art methods. The code is available at https://github.com/MVL-Lab/SigRL.

cs.LG↗

Rethinking Programmed I/O for Fast Devices, Cheap Cores, and Coherent Interconnects

Conventional wisdom holds that an efficient interface between an OS running on a CPU and a high-bandwidth I/O device should use Direct Memory Access (DMA) to offload data transfer, descriptor rings for buffering and queuing, and interrupts for asynchrony between cores and device. In this paper we question this wisdom in the light of two trends: modern and emerging cache-coherent interconnects like CXL3.0, and workloads, particularly microservices and serverless computing. Like some others before us, we argue that the assumptions of the DMA-based model are obsolete, and in many use-cases programmed I/O, where the CPU explicitly transfers data and control information to and from a device via loads and stores, delivers a more efficient system. However, we push this idea much further. We show, in a real hardware implementation, the gains in latency for fine-grained communication achievable using an open cache-coherence protocol which exposes cache transitions to a smart device, and that throughput is competitive with DMA over modern interconnects. We also demonstrate three use-cases: fine-grained RPC-style invocation of functions on an accelerator, offloading of operators in a streaming dataflow engine, and a network interface targeting serverless functions, comparing our use of coherence with both traditional DMA-style interaction and a highly-optimized implementation using memory-mapped programmed I/O over PCIe.

cs.AR↗

The NIC should be part of the OS

The network interface adapter (NIC) is a critical component of a cloud server occupying a unique position. Not only is network performance vital to efficient operation of the machine, but unlike compute accelerators like GPUs, the network subsystem must react to unpredictable events like the arrival of a network packet and communicate with the appropriate application end point with minimal latency. Current approaches to server stacks navigate a trade-off between flexibility, efficiency, and performance: the fastest kernel-bypass approaches dedicate cores to applications, busy-wait on receive queues, etc. while more flexible approaches appropriate to more dynamic workload mixes incur much greater software overhead on the data path. However, we reject this trade-off, which we ascribe to an arbitrary (and sub-optimal) split in system state between the OS and the NIC. Instead, by exploiting the properties of cache-coherent interconnects and integrating the NIC closely with the OS kernel, we can achieve something surprising: performance for RPC workloads better than the fastest kernelbypass approaches without sacrificing the robustness and dynamic adaptation of kernel-based network subsystems.

cs.OS↗

Unveil Inversion and Invariance in Flow Transformer for Versatile Image Editing

Leveraging the large generative prior of the flow transformer for tuning-free image editing requires authentic inversion to project the image into the model's domain and a flexible invariance control mechanism to preserve non-target contents. However, the prevailing diffusion inversion performs deficiently in flow-based models, and the invariance control cannot reconcile diverse rigid and non-rigid editing tasks. To address these, we systematically analyze the \textbf{inversion and invariance} control based on the flow transformer. Specifically, we unveil that the Euler inversion shares a similar structure to DDIM yet is more susceptible to the approximation error. Thus, we propose a two-stage inversion to first refine the velocity estimation and then compensate for the leftover error, which pivots closely to the model prior and benefits editing. Meanwhile, we propose the invariance control that manipulates the text features within the adaptive layer normalization, connecting the changes in the text prompt to image semantics. This mechanism can simultaneously preserve the non-target contents while allowing rigid and non-rigid manipulation, enabling a wide range of editing types such as visual text, quantity, facial expression, etc. Experiments on versatile scenarios validate that our framework achieves flexible and accurate editing, unlocking the potential of the flow transformer for versatile image editing.

cs.CV↗

From Challenges and Pitfalls to Recommendations and Opportunities: Implementing Federated Learning in Healthcare

Federated learning holds great potential for enabling large-scale healthcare research and collaboration across multiple centres while ensuring data privacy and security are not compromised. Although numerous recent studies suggest or utilize federated learning based methods in healthcare, it remains unclear which ones have potential clinical utility. This review paper considers and analyzes the most recent studies up to May 2024 that describe federated learning based methods in healthcare. After a thorough review, we find that the vast majority are not appropriate for clinical use due to their methodological flaws and/or underlying biases which include but are not limited to privacy concerns, generalization issues, and communication costs. As a result, the effectiveness of federated learning in healthcare is significantly compromised. To overcome these challenges, we provide recommendations and promising opportunities that might be implemented to resolve these problems and improve the quality of model development in federated learning with healthcare.

cs.LG↗

Textualize Visual Prompt for Image Editing via Diffusion Bridge

Visual prompt, a pair of before-and-after edited images, can convey indescribable imagery transformations and prosper in image editing. However, current visual prompt methods rely on a pretrained text-guided image-to-image generative model that requires a triplet of text, before, and after images for retraining over a text-to-image model. Such crafting triplets and retraining processes limit the scalability and generalization of editing. In this paper, we present a framework based on any single text-to-image model without reliance on the explicit image-to-image model thus enhancing the generalizability and scalability. Specifically, by leveraging the probability-flow ordinary equation, we construct a diffusion bridge to transfer the distribution between before-and-after images under the text guidance. By optimizing the text via the bridge, the framework adaptively textualizes the editing transformation conveyed by visual prompts into text embeddings without other models. Meanwhile, we introduce differential attention control during text optimization, which disentangles the text embedding from the invariance of the before-and-after images and makes it solely capture the delicate transformation and generalize to edit various images. Experiments on real images validate competitive results on the generalization, contextual coherence, and high fidelity for delicate editing with just one image pair as the visual prompt.

cs.CV↗

Plug-and-Play Tri-Branch Invertible Block for Image Rescaling

High-resolution (HR) images are commonly downscaled to low-resolution (LR) to reduce bandwidth, followed by upscaling to restore their original details. Recent advancements in image rescaling algorithms have employed invertible neural networks (INNs) to create a unified framework for downscaling and upscaling, ensuring a one-to-one mapping between LR and HR images. Traditional methods, utilizing dual-branch based vanilla invertible blocks, process high-frequency and low-frequency information separately, often relying on specific distributions to model high-frequency components. However, processing the low-frequency component directly in the RGB domain introduces channel redundancy, limiting the efficiency of image reconstruction. To address these challenges, we propose a plug-and-play tri-branch invertible block (T-InvBlocks) that decomposes the low-frequency branch into luminance (Y) and chrominance (CbCr) components, reducing redundancy and enhancing feature processing. Additionally, we adopt an all-zero mapping strategy for high-frequency components during upscaling, focusing essential rescaling information within the LR image. Our T-InvBlocks can be seamlessly integrated into existing rescaling models, improving performance in both general rescaling tasks and scenarios involving lossy compression. Extensive experiments confirm that our method advances the state of the art in HR image reconstruction.

eess.IV↗

Exploring applications of topological data analysis in stock index movement prediction

Topological Data Analysis (TDA) has recently gained significant attention in the field of financial prediction. However, the choice of point cloud construction methods, topological feature representations, and classification models has a substantial impact on prediction results. This paper addresses the classification problem of stock index movement. First, we construct point clouds for stock indices using three different methods. Next, we apply TDA to extract topological structures from the point clouds. Four distinct topological features are computed to represent the patterns in the data, and 15 combinations of these features are enumerated and input into six different machine learning models. We evaluate the predictive performance of various TDA configurations by conducting index movement classification tasks on datasets such as CSI, DAX, HSI and FTSE providing insights into the efficiency of different TDA setups.

cs.LG↗

FPsPIN: An FPGA-based Open-Hardware Research Platform for Processing in the Network

In the era of post-Moore computing, network offload emerges as a solution to two challenges: the imperative for low-latency communication and the push towards hardware specialisation. Various methods have been employed to offload protocol- and data-processing onto network interface cards (NICs), from firmware modification to running full Linux on NICs for application execution. The sPIN project enables users to define handlers executed upon packet arrival. While simulations show sPIN's potential across diverse workloads, a full-system evaluation is lacking. This work presents FPsPIN, a full FPGA-based implementation of sPIN. FPsPIN is showcased through offloaded MPI datatype processing, achieving a 96% overlap ratio. FPsPIN provides an adaptable open-source research platform for researchers to conduct end-to-end experiments on smart NICs.

cs.NI↗

InstructBrush: Learning Attention-based Instruction Optimization for Image Editing

In recent years, instruction-based image editing methods have garnered significant attention in image editing. However, despite encompassing a wide range of editing priors, these methods are helpless when handling editing tasks that are challenging to accurately describe through language. We propose InstructBrush, an inversion method for instruction-based image editing methods to bridge this gap. It extracts editing effects from exemplar image pairs as editing instructions, which are further applied for image editing. Two key techniques are introduced into InstructBrush, Attention-based Instruction Optimization and Transformation-oriented Instruction Initialization, to address the limitations of the previous method in terms of inversion effects and instruction generalization. To explore the ability of instruction inversion methods to guide image editing in open scenarios, we establish a TransformationOriented Paired Benchmark (TOP-Bench), which contains a rich set of scenes and editing types. The creation of this benchmark paves the way for further exploration of instruction inversion. Quantitatively and qualitatively, our approach achieves superior performance in editing and is more semantically consistent with the target editing effects.

cs.GR↗

Enhanced Index Modulation Aided Non-Orthogonal Multiple Access via Constellation Rotation

Non-orthogonal multiple access (NOMA) has been widely nominated as an emerging spectral efficiency (SE) multiple access technique for the next generation of wireless communication network. To meet the growing demands in massive connectivity and huge data in transmission, a novel index modulation aided NOMA with the rotation of signal constellation of low power users (IM-NOMA-RC) is developed to the downlink transmission. In the proposed IM-NOMA-RC system, the users are classified into far-user group and near-user group according to their channel conditions, where the rotation constellation based IM operation is performed only on the users who belong to the near-user group that are allocated lower power compared with the far ones to transmit extra information. In the proposed IM-NOMA-RC, all the subcarriers are activated to transmit information to multiple users to achieve higher SE. With the aid of the multiple dimension modulation in IM-NOMA-RC, more users can be supported over an orthogonal resource block. Then, both maximum likelihood (ML) detector and successive interference cancellation (SIC) detector are studied for all the user. Numerical simulation results of the proposed IM-NOMARC scheme are investigate for the ML detector and the SIC detector for each users, which shows that proposed scheme can outperform conventional NOMA.

cs.IT↗

Molecular De Novo Design through Transformer-based Reinforcement Learning

In this work, we introduce a method to fine-tune a Transformer-based generative model for molecular de novo design. Leveraging the superior sequence learning capacity of Transformers over Recurrent Neural Networks (RNNs), our model can generate molecular structures with desired properties effectively. In contrast to the traditional RNN-based models, our proposed method exhibits superior performance in generating compounds predicted to be active against various biological targets, capturing long-term dependencies in the molecular structure sequence. The model's efficacy is demonstrated across numerous tasks, including generating analogues to a query structure and producing compounds with particular attributes, outperforming the baseline RNN-based methods. Our approach can be used for scaffold hopping, library expansion starting from a single molecule, and generating compounds with high predicted activity against biological targets.

cs.LG↗

Development of helium turbine loss model based on knowledge transfer with Neural Network and its application on aerodynamic design

Helium turbines are widely used in the Closed Brayton Cycle for power generation and aerospace applications. The primary concerns of designing highly loaded helium turbines include choosing between conventional and contra-rotating designs and the guidelines for selecting design parameters. A loss model serving as an evaluation means is the key to addressing this issue. Due to the property disparities between helium and air, turbines utilizing either as working fluid experience distinct loss mechanisms. Consequently, directly applying gas turbine experience to the design of helium turbines leads to inherent inaccuracies. A helium turbine loss model is developed by combining knowledge transfer and the Neural Network method to accurately predict performance at design and off-design points. By utilizing the loss model, design parameter selection guidelines for helium turbines are obtained. A comparative analysis is conducted of conventional and contra-rotating helium turbine designs. Results show that the prediction errors of the loss model are below 0.5% at over 90% of test samples, surpassing the accuracy achieved by the gas turbine loss model. Design parameter selection guidelines for helium turbines differ significantly from those based on gas turbine experience. The contra-rotating helium turbine design exhibits advantages in size, weight, and aerodynamic performance.

physics.app-ph↗

MIRACLE: Multi-task Learning based Interpretable Regulation of Autoimmune Diseases through Common Latent Epigenetics

DNA methylation is a crucial regulator of gene transcription and has been linked to various diseases, including autoimmune diseases and cancers. However, diagnostics based on DNA methylation face challenges due to large feature sets and small sample sizes, resulting in overfitting and suboptimal performance. To address these issues, we propose MIRACLE, a novel interpretable neural network that leverages autoencoder-based multi-task learning to integrate multiple datasets and jointly identify common patterns in DNA methylation. MIRACLE's architecture reflects the relationships between methylation sites, genes, and pathways, ensuring biological interpretability and meaningfulness. The network comprises an encoder and a decoder, with a bottleneck layer representing pathway information as the basic unit of heredity. Customized defined MaskedLinear Layer is constrained by site-gene-pathway graph adjacency matrix information, which provides explainability and expresses the site-gene-pathway hierarchical structure explicitly. And from the embedding, there are different multi-task classifiers to predict diseases. Tested on six datasets, including rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, inflammatory bowel disease, psoriasis, and type 1 diabetes, MIRACLE demonstrates robust performance in identifying common functions of DNA methylation across different phenotypes, with higher accuracy in prediction dieseases than baseline methods. By incorporating biological prior knowledge, MIRACLE offers a meaningful and interpretable framework for DNA methylation data analysis in the context of autoimmune diseases.

cs.LG↗

When Source-Free Domain Adaptation Meets Learning with Noisy Labels

Recent state-of-the-art source-free domain adaptation (SFDA) methods have focused on learning meaningful cluster structures in the feature space, which have succeeded in adapting the knowledge from source domain to unlabeled target domain without accessing the private source data. However, existing methods rely on the pseudo-labels generated by source models that can be noisy due to domain shift. In this paper, we study SFDA from the perspective of learning with label noise (LLN). Unlike the label noise in the conventional LLN scenario, we prove that the label noise in SFDA follows a different distribution assumption. We also prove that such a difference makes existing LLN methods that rely on their distribution assumptions unable to address the label noise in SFDA. Empirical evidence suggests that only marginal improvements are achieved when applying the existing LLN methods to solve the SFDA problem. On the other hand, although there exists a fundamental difference between the label noise in the two scenarios, we demonstrate theoretically that the early-time training phenomenon (ETP), which has been previously observed in conventional label noise settings, can also be observed in the SFDA problem. Extensive experiments demonstrate significant improvements to existing SFDA algorithms by leveraging ETP to address the label noise in SFDA.

cs.LG↗