arXiv subjects

Pengwei Hu

Publications and source records attributed to Pengwei Hu.

6 recordsLinked to original sources

arXiv2026

scKDGM: KAN-guided Dynamic Graph Masked Learning for Single-Cell RNA-seq Clustering

Single-cell RNA sequencing (scRNA-seq) clustering is essential for identifying cell types, but high dimensionality, sparsity, dropout, and technical noise hinder robust expression representation and cell graph construction. Existing masked autoencoders mainly use expression recovery for feature reconstruction, while graph clustering methods usually depend on fixed KNN graphs and do not feed recovered expression back into graph optimization. We propose scKDGM, a KAN-guided dynamic graph masked learning framework for scRNA-seq clustering. scKDGM uses graph-aware distribution preserving gene masking (GDP-Mask) to perturb cell identity, a KAN-based TAKGCN encoder to learn masked-view representations, mask-guided expression recovery to construct a dynamic graph, and cross-view contrastive learning to transfer recovery signals into topology updates. A ZINB loss models overdispersion and zero inflation. Experiments on 12 real scRNA-seq datasets show that scKDGM outperforms 10 baselines in average NMI and ARI.

cs.LG↗

arXiv2026

Personalization Meets Safety:Mechanisms,Risks,and Mitigations in Personalized LLMs

Large Language Models (LLMs) have enabled increasingly personalized interactions by adapting to users' preferences, contexts, and long-term histories. However, the mechanisms that enable personalization also expand the safety landscape in ways not systematically addressed by existing literature. Existing reviews typically focus either on personalization or safety, leaving their intersection largely unexplored. We present the first comprehensive, safety-aware review of personalized LLMs. We organize personalization along three dimensions-user representation, personalization paradigm, and evaluation-and introduce a unified taxonomy of safety risks. At the representation level, we analyze risks arising from diverse user representations. Across mainstream personalization paradigms, we delineate vulnerabilities inherent to prompting, retrieval augmentation, parameter fine-tuning, reinforcement learning, Mixture-of-Experts (MoE), pruning, agent frameworks, and multimodal personalization, and synthesize mitigation strategies across the model lifecycle. Beyond these fine-grained risks, we characterize paradigm-agnostic safety risks arising from personalized adaptation. We further summarize personalized datasets and evaluation methodologies. Through a case study of OpenClaw, we analyze deployment trends in personalized agent ecosystems. Our analysis reveals three structural inadequacies in existing research: safety is evaluated as user-invariant rather than relational, personalization techniques are analyzed in isolation rather than in composition, and evaluation frameworks cannot capture emergent long-term risks. By jointly examining personalized representations, personalization paradigms, safety risks, defenses, and evaluation methods, we provide a unified framework for developing safe personalized LLMs and highlight key directions for future research.

cs.AI↗

arXiv2023

NutriFD: Proving the medicinal value of food nutrition based on food-disease association and treatment networks

There is rising evidence of the health benefit associated with specific dietary interventions. Current food-disease databases focus on associations and treatment relationships but haven't provided a reasonable assessment of the strength of the relationship, and lack of attention on food nutrition. There is an unmet need for a large database that can guide dietary therapy. We fill the gap with NutriFD, a scoring network based on associations and therapeutic relationships between foods and diseases. NutriFD integrates 9 databases including foods, nutrients, diseases, genes, miRNAs, compounds, disease ontology and their relationships. To our best knowledge, this database is the only one that can score the associations and therapeutic relationships of everyday foods and diseases by weighting inference scores of food compounds to diseases. In addition, NutriFD demonstrates the predictive nature of nutrients on the therapeutic relationships between foods and diseases through machine learning models, laying the foundation for a mechanistic understanding of food therapy.

q-bio.QM↗

arXiv2022

HigeNet: A Highly Efficient Modeling for Long Sequence Time Series Prediction in AIOps

Modern IT system operation demands the integration of system software and hardware metrics. As a result, it generates a massive amount of data, which can be potentially used to make data-driven operational decisions. In the basic form, the decision model needs to monitor a large set of machine data, such as CPU utilization, allocated memory, disk and network latency, and predicts the system metrics to prevent performance degradation. Nevertheless, building an effective prediction model in this scenario is rather challenging as the model has to accurately capture the long-range coupling dependency in the Multivariate Time-Series (MTS). Moreover, this model needs to have low computational complexity and can scale efficiently to the dimension of data available. In this paper, we propose a highly efficient model named HigeNet to predict the long-time sequence time series. We have deployed the HigeNet on production in the D-matrix platform. We also provide offline evaluations on several publicly available datasets as well as one online dataset to demonstrate the model's efficacy. The extensive experiments show that training time, resource usage and accuracy of the model are found to be significantly better than five state-of-the-art competing models.

cs.LG↗

arXiv2020

Diversifying Dialogue Generation with Non-Conversational Text

Neural network-based sequence-to-sequence (seq2seq) models strongly suffer from the low-diversity problem when it comes to open-domain dialogue generation. As bland and generic utterances usually dominate the frequency distribution in our daily chitchat, avoiding them to generate more interesting responses requires complex data filtering, sampling techniques or modifying the training objective. In this paper, we propose a new perspective to diversify dialogue generation by leveraging non-conversational text. Compared with bilateral conversations, non-conversational text are easier to obtain, more diverse and cover a much broader range of topics. We collect a large-scale non-conversational corpus from multi sources including forum comments, idioms and book snippets. We further present a training paradigm to effectively incorporate these text via iterative back translation. The resulting model is tested on two conversational datasets and is shown to produce significantly more diverse responses without sacrificing the relevance with context.

cs.CL↗

arXiv2019

Improving Multi-turn Dialogue Modelling with Utterance ReWriter

Recent research has made impressive progress in single-turn dialogue modelling. In the multi-turn setting, however, current models are still far from satisfactory. One major challenge is the frequently occurred coreference and information omission in our daily conversation, making it hard for machines to understand the real intention. In this paper, we propose rewriting the human utterance as a pre-process to help multi-turn dialgoue modelling. Each utterance is first rewritten to recover all coreferred and omitted information. The next processing steps are then performed based on the rewritten utterance. To properly train the utterance rewriter, we collect a new dataset with human annotations and introduce a Transformer-based utterance rewriting architecture using the pointer network. We show the proposed architecture achieves remarkably good performance on the utterance rewriting task. The trained utterance rewriter can be easily integrated into online chatbots and brings general improvement over different domains.

cs.CL↗