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Peter Bickel

Publications and source records attributed to Peter Bickel.

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Nonparametric Evaluation of Noisy ICA Solutions

Independent Component Analysis (ICA) was introduced in the 1980's as a model for Blind Source Separation (BSS), which refers to the process of recovering the sources underlying a mixture of signals, with little knowledge about the source signals or the mixing process. While there are many sophisticated algorithms for estimation, different methods have different shortcomings. In this paper, we develop a nonparametric score to adaptively pick the right algorithm for ICA with arbitrary Gaussian noise. The novelty of this score stems from the fact that it just assumes a finite second moment of the data and uses the characteristic function to evaluate the quality of the estimated mixing matrix without any knowledge of the parameters of the noise distribution. In addition, we propose some new contrast functions and algorithms that enjoy the same fast computability as existing algorithms like FASTICA and JADE but work in domains where the former may fail. While these also may have weaknesses, our proposed diagnostic, as shown by our simulations, can remedy them. Finally, we propose a theoretical framework to analyze the local and global convergence properties of our algorithms.

math.ST

Network Inference Using the Hub Model and Variants

Statistical network analysis primarily focuses on inferring the parameters of an observed network. In many applications, especially in the social sciences, the observed data is the groups formed by individual subjects. In these applications, the network is itself a parameter of a statistical model. Zhao and Weko (2019) propose a model-based approach, called the hub model, to infer implicit networks from grouping behavior. The hub model assumes that each member of the group is brought together by a member of the group called the hub. The set of members which can serve as a hub is called the hub set. The hub model belongs to the family of Bernoulli mixture models. Identifiability of Bernoulli mixture model parameters is a notoriously difficult problem. This paper proves identifiability of the hub model parameters and estimation consistency under mild conditions. Furthermore, this paper generalizes the hub model by introducing a model component that allows hubless groups in which individual nodes spontaneously appear independent of any other individual. We refer to this additional component as the null component. The new model bridges the gap between the hub model and the degenerate case of the mixture model -- the Bernoulli product. Identifiability and consistency are also proved for the new model. In addition, a penalized likelihood approach is proposed to estimate the hub set when it is unknown.

stat.ME

Identifiability and consistency of network inference using the hub model and variants

Statistical network analysis primarily focuses on inferring the parameters of an observed network. In many applications, especially in the social sciences, the observed data is the groups formed by individual subjects. In these applications, the network is itself a parameter of a statistical model. Zhao and Weko (2019) propose a model-based approach, called the hub model, to infer implicit networks from grouping behavior. The hub model assumes that each member of the group is brought together by a member of the group called the hub. The hub model belongs to the family of Bernoulli mixture models. Identifiability of parameters is a notoriously difficult problem for Bernoulli mixture models. This paper proves identifiability of the hub model parameters and estimation consistency under mild conditions. Furthermore, this paper generalizes the hub model by introducing a model component that allows hubless groups in which individual nodes spontaneously appear independent of any other individual. We refer to this additional component as the null component. The new model bridges the gap between the hub model and the degenerate case of the mixture model -- the Bernoulli product. Identifiability and consistency are also proved for the new model. Numerical studies are provided to demonstrate the theoretical results.

math.ST

Asymptotic normality of maximum likelihood and its variational approximation for stochastic blockmodels

Variational methods for parameter estimation are an active research area, potentially offering computationally tractable heuristics with theoretical performance bounds. We build on recent work that applies such methods to network data, and establish asymptotic normality rates for parameter estimates of stochastic blockmodel data, by either maximum likelihood or variational estimation. The result also applies to various sub-models of the stochastic blockmodel found in the literature.

math.ST

A model for sequential evolution of ligands by exponential enrichment (SELEX) data

A Systematic Evolution of Ligands by EXponential enrichment (SELEX) experiment begins in round one with a random pool of oligonucleotides in equilibrium solution with a target. Over a few rounds, oligonucleotides having a high affinity for the target are selected. Data from a high throughput SELEX experiment consists of lists of thousands of oligonucleotides sampled after each round. Thus far, SELEX experiments have been very good at suggesting the highest affinity oligonucleotide, but modeling lower affinity recognition site variants has been difficult. Furthermore, an alignment step has always been used prior to analyzing SELEX data. We present a novel model, based on a biochemical parametrization of SELEX, which allows us to use data from all rounds to estimate the affinities of the oligonucleotides. Most notably, our model also aligns the oligonucleotides. We use our model to analyze a SELEX experiment containing double stranded DNA oligonucleotides and the transcription factor Bicoid as the target. Our SELEX model outperformed other published methods for predicting putative binding sites for Bicoid as indicated by the results of an in-vivo ChIP-chip experiment.

stat.AP

Regression on manifolds: Estimation of the exterior derivative

Collinearity and near-collinearity of predictors cause difficulties when doing regression. In these cases, variable selection becomes untenable because of mathematical issues concerning the existence and numerical stability of the regression coefficients, and interpretation of the coefficients is ambiguous because gradients are not defined. Using a differential geometric interpretation, in which the regression coefficients are interpreted as estimates of the exterior derivative of a function, we develop a new method to do regression in the presence of collinearities. Our regularization scheme can improve estimation error, and it can be easily modified to include lasso-type regularization. These estimators also have simple extensions to the "large $p$, small $n$" context.

math.ST

Efficient blind search: Optimal power of detection under computational cost constraints

Some astronomy projects require a blind search through a vast number of hypotheses to detect objects of interest. The number of hypotheses to test can be in the billions. A naive blind search over every single hypothesis would be far too costly computationally. We propose a hierarchical scheme for blind search, using various "resolution" levels. At lower resolution levels, "regions" of interest in the search space are singled out with a low computational cost. These regions are refined at intermediate resolution levels and only the most promising candidates are finally tested at the original fine resolution. The optimal search strategy is found by dynamic programming. We demonstrate the procedure for pulsar search from satellite gamma-ray observations and show that the power of the naive blind search can almost be matched with the hierarchical scheme while reducing the computational burden by more than three orders of magnitude.

stat.ME

Sharp failure rates for the bootstrap particle filter in high dimensions

We prove that the maximum of the sample importance weights in a high-dimensional Gaussian particle filter converges to unity unless the ensemble size grows exponentially in the system dimension. Our work is motivated by and parallels the derivations of Bengtsson, Bickel and Li (2007); however, we weaken their assumptions on the eigenvalues of the covariance matrix of the prior distribution and establish rigorously their strong conjecture on when weight collapse occurs. Specifically, we remove the assumption that the nonzero eigenvalues are bounded away from zero, which, although the dimension of the involved vectors grow to infinity, essentially permits the effective system dimension to be bounded. Moreover, with some restrictions on the rate of growth of the maximum eigenvalue, we relax their assumption that the eigenvalues are bounded from above, allowing the system to be dominated by a single mode.

math.ST

Curse-of-dimensionality revisited: Collapse of the particle filter in very large scale systems

It has been widely realized that Monte Carlo methods (approximation via a sample ensemble) may fail in large scale systems. This work offers some theoretical insight into this phenomenon in the context of the particle filter. We demonstrate that the maximum of the weights associated with the sample ensemble converges to one as both the sample size and the system dimension tends to infinity. Specifically, under fairly weak assumptions, if the ensemble size grows sub-exponentially in the cube root of the system dimension, the convergence holds for a single update step in state-space models with independent and identically distributed kernels. Further, in an important special case, more refined arguments show (and our simulations suggest) that the convergence to unity occurs unless the ensemble grows super-exponentially in the system dimension. The weight singularity is also established in models with more general multivariate likelihoods, e.g. Gaussian and Cauchy. Although presented in the context of atmospheric data assimilation for numerical weather prediction, our results are generally valid for high-dimensional particle filters.

math.ST

Event Weighted Tests for Detecting Periodicity in Photon Arrival Times

This paper treats the problem of detecting periodicity in a sequence of photon arrival times, which occurs, for example, in attempting to detect gamma-ray pulsars. A particular focus is on how auxiliary information, typically source intensity, background intensity, and incidence angles and energies associated with each photon arrival should be used to maximize the detection power. We construct a class of likelihood-based tests, score tests, which give rise to event weighting in a principled and natural way, and derive expressions quantifying the power of the tests. These results can be used to compare the efficacies of different weight functions, including cuts in energy and incidence angle. The test is targeted toward a template for the periodic lightcurve, and we quantify how deviation from that template affects the power of detection.

stat.ME

Hidden Markov and state space models: asymptotic analysis of exact and approximate methods for prediction, filtering, smoothing and statistical inference

State space models have long played an important role in signal processing. The Gaussian case can be treated algorithmically using the famous Kalman filter. Similarly since the 1970s there has been extensive application of Hidden Markov models in speech recognition with prediction being the most important goal. The basic theoretical work here, in the case $X$ and $Y$ finite (small) providing both algorithms and asymptotic analysis for inference is that of Baum and colleagues. During the last 30-40 years these general models have proved of great value in applications ranging from genomics to finance. Unless the $X,Y$ are jointly Gaussian or $X$ is finite and small the problem of calculating the distributions discussed and the likelihood exactly are numerically intractable and if $Y$ is not finite asymptotic analysis becomes much more difficult. Some new developments have been the construction of so-called ``particle filters'' (Monte Carlo type) methods for approximate calculation of these distributions (see Doucet et al. [4]) for instance and general asymptotic methods for analysis of statistical methods in HMM [2] and other authors. We will discuss these methods and results in the light of exponential mixing properties of the conditional (posterior) distribution of $(X_1,X_2,...)$ given $(Y_1,Y_2,...)$ already noted by Baum and Petrie and recent work of the authors Bickel, Ritov and Ryden, Del Moral and Jacod, Douc and Matias.

math.ST