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Peter J. Lally

Publications and source records attributed to Peter J. Lally.

3 recordsLinked to original sources

PerFact: Perception-Derived Fact Prompting for 3D Brain MRI Report Generation

Radiology report generation has matured almost entirely on 2D chest radiographs, where the default route to better reports is a larger backbone or a pre-training one on medical data. We revisit that assumption on 3D multi-sequence brain MRI, a volumetric multi-disease regime, and find that the model is not the lever. Zero-shot medical and radiology vision-language models transfer poorly to brain MRI, with chest radiograph specialists failing most conspicuously, and five backbones fine-tuned identically across three model families and an order of magnitude in scale differ only marginally. What determines the quality of the report is the information injected into the prompt. We delegate perception to upstream 3D segmentation and classification, serialize their outputs into a structured fact sentence, and prompt a LoRA-adapted vision-language model with it; we call this \textbf{PerFact}. In a controlled study that fixes the backbone, data split, target reports, and adaptation while varying only the injected grounding, perception-derived facts outperform retrieved prior reports, retrieval becomes redundant once facts are present, and end-to-end predicted facts remain effective without any ground-truth annotation at inference. The residual gap between predicted and oracle facts is explained by the granularity of the facts rather than by the generator. Closed-ended visual question answering comes at no measurable cost to report quality, though the grounding source has little effect on it. On 3D brain MRI, grounding information, not model choice, is the dominant controllable factor in report quality.

cs.CV

From Coarse to Continuous: Progressive Refinement Implicit Neural Representation for Motion-Robust Anisotropic MRI Reconstruction

In motion-robust magnetic resonance imaging (MRI), slice-to-volume reconstruction is critical for recovering anatomically consistent 3D brain volumes from 2D slices, especially under accelerated acquisitions or patient motion. However, this task remains challenging due to hierarchical structural disruptions. It includes local detail loss from k-space undersampling, global structural aliasing caused by motion, and volumetric anisotropy. Therefore, we propose a progressive refinement implicit neural representation (PR-INR) framework. Our PR-INR unifies motion correction, structural refinement, and volumetric synthesis within a geometry-aware coordinate space. Specifically, a motion-aware diffusion module is first employed to generate coarse volumetric reconstructions that suppress motion artifacts and preserve global anatomical structures. Then, we introduce an implicit detail restoration module that performs residual refinement by aligning spatial coordinates with visual features. It corrects local structures and enhances boundary precision. Further, a voxel continuous-aware representation module represents the image as a continuous function over 3D coordinates. It enables accurate inter-slice completion and high-frequency detail recovery. We evaluate PR-INR on five public MRI datasets under various motion conditions (3% and 5% displacement), undersampling rates (4x and 8x) and slice resolutions (scale = 5). Experimental results demonstrate that PR-INR outperforms state-of-the-art methods in both quantitative reconstruction metrics and visual quality. It further shows generalization and robustness across diverse unseen domains.

eess.IV

Cyclic Self-Supervised Diffusion for Ultra Low-field to High-field MRI Synthesis

Synthesizing high-quality images from low-field MRI holds significant potential. Low-field MRI is cheaper, more accessible, and safer, but suffers from low resolution and poor signal-to-noise ratio. This synthesis process can reduce reliance on costly acquisitions and expand data availability. However, synthesizing high-field MRI still suffers from a clinical fidelity gap. There is a need to preserve anatomical fidelity, enhance fine-grained structural details, and bridge domain gaps in image contrast. To address these issues, we propose a \emph{cyclic self-supervised diffusion (CSS-Diff)} framework for high-field MRI synthesis from real low-field MRI data. Our core idea is to reformulate diffusion-based synthesis under a cycle-consistent constraint. It enforces anatomical preservation throughout the generative process rather than just relying on paired pixel-level supervision. The CSS-Diff framework further incorporates two novel processes. The slice-wise gap perception network aligns inter-slice inconsistencies via contrastive learning. The local structure correction network enhances local feature restoration through self-reconstruction of masked and perturbed patches. Extensive experiments on cross-field synthesis tasks demonstrate the effectiveness of our method, achieving state-of-the-art performance (e.g., 31.80 $\pm$ 2.70 dB in PSNR, 0.943 $\pm$ 0.102 in SSIM, and 0.0864 $\pm$ 0.0689 in LPIPS). Beyond pixel-wise fidelity, our method also preserves fine-grained anatomical structures compared with the original low-field MRI (e.g., left cerebral white matter error drops from 12.1$\%$ to 2.1$\%$, cortex from 4.2$\%$ to 3.7$\%$). To conclude, our CSS-Diff can synthesize images that are both quantitatively reliable and anatomically consistent.

cs.CV