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Peter J. Liu

Publications and source records attributed to Peter J. Liu.

29 records · Page 2Linked to original sources

Likelihood Ratios for Out-of-Distribution Detection

Discriminative neural networks offer little or no performance guarantees when deployed on data not generated by the same process as the training distribution. On such out-of-distribution (OOD) inputs, the prediction may not only be erroneous, but confidently so, limiting the safe deployment of classifiers in real-world applications. One such challenging application is bacteria identification based on genomic sequences, which holds the promise of early detection of diseases, but requires a model that can output low confidence predictions on OOD genomic sequences from new bacteria that were not present in the training data. We introduce a genomics dataset for OOD detection that allows other researchers to benchmark progress on this important problem. We investigate deep generative model based approaches for OOD detection and observe that the likelihood score is heavily affected by population level background statistics. We propose a likelihood ratio method for deep generative models which effectively corrects for these confounding background statistics. We benchmark the OOD detection performance of the proposed method against existing approaches on the genomics dataset and show that our method achieves state-of-the-art performance. We demonstrate the generality of the proposed method by showing that it significantly improves OOD detection when applied to deep generative models of images.

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SummAE: Zero-Shot Abstractive Text Summarization using Length-Agnostic Auto-Encoders

We propose an end-to-end neural model for zero-shot abstractive text summarization of paragraphs, and introduce a benchmark task, ROCSumm, based on ROCStories, a subset for which we collected human summaries. In this task, five-sentence stories (paragraphs) are summarized with one sentence, using human summaries only for evaluation. We show results for extractive and human baselines to demonstrate a large abstractive gap in performance. Our model, SummAE, consists of a denoising auto-encoder that embeds sentences and paragraphs in a common space, from which either can be decoded. Summaries for paragraphs are generated by decoding a sentence from the paragraph representations. We find that traditional sequence-to-sequence auto-encoders fail to produce good summaries and describe how specific architectural choices and pre-training techniques can significantly improve performance, outperforming extractive baselines. The data, training, evaluation code, and best model weights are open-sourced.

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Using Ontologies To Improve Performance In Massively Multi-label Prediction Models

Massively multi-label prediction/classification problems arise in environments like health-care or biology where very precise predictions are useful. One challenge with massively multi-label problems is that there is often a long-tailed frequency distribution for the labels, which results in few positive examples for the rare labels. We propose a solution to this problem by modifying the output layer of a neural network to create a Bayesian network of sigmoids which takes advantage of ontology relationships between the labels to help share information between the rare and the more common labels. We apply this method to the two massively multi-label tasks of disease prediction (ICD-9 codes) and protein function prediction (Gene Ontology terms) and obtain significant improvements in per-label AUROC and average precision for less common labels.

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MeanSum: A Neural Model for Unsupervised Multi-document Abstractive Summarization

Abstractive summarization has been studied using neural sequence transduction methods with datasets of large, paired document-summary examples. However, such datasets are rare and the models trained from them do not generalize to other domains. Recently, some progress has been made in learning sequence-to-sequence mappings with only unpaired examples. In our work, we consider the setting where there are only documents (product or business reviews) with no summaries provided, and propose an end-to-end, neural model architecture to perform unsupervised abstractive summarization. Our proposed model consists of an auto-encoder where the mean of the representations of the input reviews decodes to a reasonable summary-review while not relying on any review-specific features. We consider variants of the proposed architecture and perform an ablation study to show the importance of specific components. We show through automated metrics and human evaluation that the generated summaries are highly abstractive, fluent, relevant, and representative of the average sentiment of the input reviews. Finally, we collect a reference evaluation dataset and show that our model outperforms a strong extractive baseline.

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Learning to Write Notes in Electronic Health Records

Clinicians spend a significant amount of time inputting free-form textual notes into Electronic Health Records (EHR) systems. Much of this documentation work is seen as a burden, reducing time spent with patients and contributing to clinician burnout. With the aspiration of AI-assisted note-writing, we propose a new language modeling task predicting the content of notes conditioned on past data from a patient's medical record, including patient demographics, labs, medications, and past notes. We train generative models using the public, de-identified MIMIC-III dataset and compare generated notes with those in the dataset on multiple measures. We find that much of the content can be predicted, and that many common templates found in notes can be learned. We discuss how such models can be useful in supporting assistive note-writing features such as error-detection and auto-complete.

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Scalable and accurate deep learning for electronic health records

Predictive modeling with electronic health record (EHR) data is anticipated to drive personalized medicine and improve healthcare quality. Constructing predictive statistical models typically requires extraction of curated predictor variables from normalized EHR data, a labor-intensive process that discards the vast majority of information in each patient's record. We propose a representation of patients' entire, raw EHR records based on the Fast Healthcare Interoperability Resources (FHIR) format. We demonstrate that deep learning methods using this representation are capable of accurately predicting multiple medical events from multiple centers without site-specific data harmonization. We validated our approach using de-identified EHR data from two U.S. academic medical centers with 216,221 adult patients hospitalized for at least 24 hours. In the sequential format we propose, this volume of EHR data unrolled into a total of 46,864,534,945 data points, including clinical notes. Deep learning models achieved high accuracy for tasks such as predicting in-hospital mortality (AUROC across sites 0.93-0.94), 30-day unplanned readmission (AUROC 0.75-0.76), prolonged length of stay (AUROC 0.85-0.86), and all of a patient's final discharge diagnoses (frequency-weighted AUROC 0.90). These models outperformed state-of-the-art traditional predictive models in all cases. We also present a case-study of a neural-network attribution system, which illustrates how clinicians can gain some transparency into the predictions. We believe that this approach can be used to create accurate and scalable predictions for a variety of clinical scenarios, complete with explanations that directly highlight evidence in the patient's chart.

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Beyond Word Importance: Contextual Decomposition to Extract Interactions from LSTMs

The driving force behind the recent success of LSTMs has been their ability to learn complex and non-linear relationships. Consequently, our inability to describe these relationships has led to LSTMs being characterized as black boxes. To this end, we introduce contextual decomposition (CD), an interpretation algorithm for analysing individual predictions made by standard LSTMs, without any changes to the underlying model. By decomposing the output of a LSTM, CD captures the contributions of combinations of words or variables to the final prediction of an LSTM. On the task of sentiment analysis with the Yelp and SST data sets, we show that CD is able to reliably identify words and phrases of contrasting sentiment, and how they are combined to yield the LSTM's final prediction. Using the phrase-level labels in SST, we also demonstrate that CD is able to successfully extract positive and negative negations from an LSTM, something which has not previously been done.

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Unsupervised Pretraining for Sequence to Sequence Learning

This work presents a general unsupervised learning method to improve the accuracy of sequence to sequence (seq2seq) models. In our method, the weights of the encoder and decoder of a seq2seq model are initialized with the pretrained weights of two language models and then fine-tuned with labeled data. We apply this method to challenging benchmarks in machine translation and abstractive summarization and find that it significantly improves the subsequent supervised models. Our main result is that pretraining improves the generalization of seq2seq models. We achieve state-of-the art results on the WMT English$\rightarrow$German task, surpassing a range of methods using both phrase-based machine translation and neural machine translation. Our method achieves a significant improvement of 1.3 BLEU from the previous best models on both WMT'14 and WMT'15 English$\rightarrow$German. We also conduct human evaluations on abstractive summarization and find that our method outperforms a purely supervised learning baseline in a statistically significant manner.

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Generating Wikipedia by Summarizing Long Sequences

We show that generating English Wikipedia articles can be approached as a multi- document summarization of source documents. We use extractive summarization to coarsely identify salient information and a neural abstractive model to generate the article. For the abstractive model, we introduce a decoder-only architecture that can scalably attend to very long sequences, much longer than typical encoder- decoder architectures used in sequence transduction. We show that this model can generate fluent, coherent multi-sentence paragraphs and even whole Wikipedia articles. When given reference documents, we show it can extract relevant factual information as reflected in perplexity, ROUGE scores and human evaluations.

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Online and Linear-Time Attention by Enforcing Monotonic Alignments

Recurrent neural network models with an attention mechanism have proven to be extremely effective on a wide variety of sequence-to-sequence problems. However, the fact that soft attention mechanisms perform a pass over the entire input sequence when producing each element in the output sequence precludes their use in online settings and results in a quadratic time complexity. Based on the insight that the alignment between input and output sequence elements is monotonic in many problems of interest, we propose an end-to-end differentiable method for learning monotonic alignments which, at test time, enables computing attention online and in linear time. We validate our approach on sentence summarization, machine translation, and online speech recognition problems and achieve results competitive with existing sequence-to-sequence models.

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Get To The Point: Summarization with Pointer-Generator Networks

Neural sequence-to-sequence models have provided a viable new approach for abstractive text summarization (meaning they are not restricted to simply selecting and rearranging passages from the original text). However, these models have two shortcomings: they are liable to reproduce factual details inaccurately, and they tend to repeat themselves. In this work we propose a novel architecture that augments the standard sequence-to-sequence attentional model in two orthogonal ways. First, we use a hybrid pointer-generator network that can copy words from the source text via pointing, which aids accurate reproduction of information, while retaining the ability to produce novel words through the generator. Second, we use coverage to keep track of what has been summarized, which discourages repetition. We apply our model to the CNN / Daily Mail summarization task, outperforming the current abstractive state-of-the-art by at least 2 ROUGE points.

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