arXiv subjects

Pheng-Ann Heng

Publications and source records attributed to Pheng-Ann Heng.

At least 109 records · Page 6Linked to original sources

arXiv2025

Landmark-Free Preoperative-to-Intraoperative Registration in Laparoscopic Liver Resection

Liver registration by overlaying preoperative 3D models onto intraoperative 2D frames can assist surgeons in perceiving the spatial anatomy of the liver clearly for a higher surgical success rate. Existing registration methods rely heavily on anatomical landmark-based workflows, which encounter two major limitations: 1) ambiguous landmark definitions fail to provide efficient markers for registration; 2) insufficient integration of intraoperative liver visual information in shape deformation modeling. To address these challenges, in this paper, we propose a landmark-free preoperative-to-intraoperative registration framework utilizing effective self-supervised learning, termed \ourmodel. This framework transforms the conventional 3D-2D workflow into a 3D-3D registration pipeline, which is then decoupled into rigid and non-rigid registration subtasks. \ourmodel~first introduces a feature-disentangled transformer to learn robust correspondences for recovering rigid transformations. Further, a structure-regularized deformation network is designed to adjust the preoperative model to align with the intraoperative liver surface. This network captures structural correlations through geometry similarity modeling in a low-rank transformer network. To facilitate the validation of the registration performance, we also construct an in-vivo registration dataset containing liver resection videos of 21 patients, called \emph{P2I-LReg}, which contains 346 keyframes that provide a global view of the liver together with liver mask annotations and calibrated camera intrinsic parameters. Extensive experiments and user studies on both synthetic and in-vivo datasets demonstrate the superiority and potential clinical applicability of our method.

cs.CV↗

arXiv2025

Rethinking End-to-End 2D to 3D Scene Segmentation in Gaussian Splatting

Lifting multi-view 2D instance segmentation to a radiance field has proven to be effective to enhance 3D understanding. Existing methods rely on direct matching for end-to-end lifting, yielding inferior results; or employ a two-stage solution constrained by complex pre- or post-processing. In this work, we design a new end-to-end object-aware lifting approach, named Unified-Lift that provides accurate 3D segmentation based on the 3D Gaussian representation. To start, we augment each Gaussian point with an additional Gaussian-level feature learned using a contrastive loss to encode instance information. Importantly, we introduce a learnable object-level codebook to account for individual objects in the scene for an explicit object-level understanding and associate the encoded object-level features with the Gaussian-level point features for segmentation predictions. While promising, achieving effective codebook learning is non-trivial and a naive solution leads to degraded performance. Therefore, we formulate the association learning module and the noisy label filtering module for effective and robust codebook learning. We conduct experiments on three benchmarks: LERF-Masked, Replica, and Messy Rooms datasets. Both qualitative and quantitative results manifest that our Unified-Lift clearly outperforms existing methods in terms of segmentation quality and time efficiency. The code is publicly available at \href{https://github.com/Runsong123/Unified-Lift}{https://github.com/Runsong123/Unified-Lift}.

cs.CV↗

arXiv2025

UniHOPE: A Unified Approach for Hand-Only and Hand-Object Pose Estimation

Estimating the 3D pose of hand and potential hand-held object from monocular images is a longstanding challenge. Yet, existing methods are specialized, focusing on either bare-hand or hand interacting with object. No method can flexibly handle both scenarios and their performance degrades when applied to the other scenario. In this paper, we propose UniHOPE, a unified approach for general 3D hand-object pose estimation, flexibly adapting both scenarios. Technically, we design a grasp-aware feature fusion module to integrate hand-object features with an object switcher to dynamically control the hand-object pose estimation according to grasping status. Further, to uplift the robustness of hand pose estimation regardless of object presence, we generate realistic de-occluded image pairs to train the model to learn object-induced hand occlusions, and formulate multi-level feature enhancement techniques for learning occlusion-invariant features. Extensive experiments on three commonly-used benchmarks demonstrate UniHOPE's SOTA performance in addressing hand-only and hand-object scenarios. Code will be released on https://github.com/JoyboyWang/UniHOPE_Pytorch.

cs.CV↗

arXiv2025

SciVerse: Unveiling the Knowledge Comprehension and Visual Reasoning of LMMs on Multi-modal Scientific Problems

The rapid advancement of Large Multi-modal Models (LMMs) has enabled their application in scientific problem-solving, yet their fine-grained capabilities remain under-explored. In this paper, we introduce SciVerse, a multi-modal scientific evaluation benchmark to thoroughly assess LMMs across 5,735 test instances in five distinct versions. We aim to investigate three key dimensions of LMMs: scientific knowledge comprehension, multi-modal content interpretation, and Chain-of-Thought (CoT) reasoning. To unveil whether LMMs possess sufficient scientific expertise, we first transform each problem into three versions containing different levels of knowledge required for solving, i.e., Knowledge-free, -lite, and -rich. Then, to explore how LMMs interpret multi-modal scientific content, we annotate another two versions, i.e., Vision-rich and -only, marking more question information from texts to diagrams. Comparing the results of different versions, SciVerse systematically examines the professional knowledge stock and visual perception skills of LMMs in scientific domains. In addition, to rigorously assess CoT reasoning, we propose a new scientific CoT evaluation strategy, conducting a step-wise assessment on knowledge and logical errors in model outputs. Our extensive evaluation of different LMMs on SciVerse reveals critical limitations in their scientific proficiency and provides new insights into future developments. Project page: https://sciverse-cuhk.github.io

cs.CV↗

arXiv2025

The Dual-use Dilemma in LLMs: Do Empowering Ethical Capacities Make a Degraded Utility?

Recent years have witnessed extensive efforts to enhance Large Language Models (LLMs) across various domains, alongside growing attention to their ethical implications. However, a critical challenge remains largely overlooked: LLMs must balance between rejecting harmful requests for safety and accommodating legitimate ones for utility. This paper presents a Direct Preference Optimization (DPO) based alignment framework that achieves better overall performance by addressing this ethical-utility trade-off, using chemical domain applications as a proof-of-concept. Our alignment pipeline starts with a GPT-assisted three-phase data generation scheme, in which we create LibraChemQA, a chemical question-answering dataset comprising 31.6k triplet instances. By incorporating an innovative balanced seed in the data generation process, our framework systematically considers both legitimate and illegitimate requests. The framework also introduces a rephrasing mechanism for efficient data augmentation that enhances the model's chemical comprehension. We further develop a novel hybrid evaluation scheme with LLM judges for precise assessment of both safety and utility. Experimental results demonstrate our model's substantial improvements in overall performance where both safety and utility are considered - the resulting model outperforms leading LLMs including Claude-3, GPT-4o, and LLaMA-3 by margins of 13.44%, 7.16%, and 7.10% respectively on our released benchmark. At the end of this paper, we analyze experimental results obtained from testing DeepSeek-R1 on our benchmark and reveal the critical ethical concerns raised by this highly acclaimed model. We highlight that the long Chain-of-Thought (CoT) reasoning process employed by DeepSeek-R1, as well as other LLMs distilled from it, introduces significant ethical vulnerabilities when exposed to users.

cs.CL↗

arXiv2025

CvhSlicer 2.0: Immersive and Interactive Visualization of Chinese Visible Human Data in XR Environments

The study of human anatomy through advanced visualization techniques is crucial for medical research and education. In this work, we introduce CvhSlicer 2.0, an innovative XR system designed for immersive and interactive visualization of the Chinese Visible Human (CVH) dataset. Particularly, our proposed system operates entirely on a commercial XR headset, offering a range of visualization and interaction tools for dynamic 2D and 3D data exploration. By conducting comprehensive evaluations, our CvhSlicer 2.0 demonstrates strong capabilities in visualizing anatomical data, enhancing user engagement and improving educational effectiveness. A demo video is available at https://youtu.be/CfR72S_0N-4

cs.HC↗

arXiv2025

Overcoming Support Dilution for Robust Few-shot Semantic Segmentation

Few-shot Semantic Segmentation (FSS) is a challenging task that utilizes limited support images to segment associated unseen objects in query images. However, recent FSS methods are observed to perform worse, when enlarging the number of shots. As the support set enlarges, existing FSS networks struggle to concentrate on the high-contributed supports and could easily be overwhelmed by the low-contributed supports that could severely impair the mask predictions. In this work, we study this challenging issue, called support dilution, our goal is to recognize, select, preserve, and enhance those high-contributed supports in the raw support pool. Technically, our method contains three novel parts. First, we propose a contribution index, to quantitatively estimate if a high-contributed support dilutes. Second, we develop the Symmetric Correlation (SC) module to preserve and enhance the high-contributed support features, minimizing the distraction by the low-contributed features. Third, we design the Support Image Pruning operation, to retrieve a compact and high quality subset by discarding low-contributed supports. We conduct extensive experiments on two FSS benchmarks, COCO-20i and PASCAL-5i, the segmentation results demonstrate the compelling performance of our solution over state-of-the-art FSS approaches. Besides, we apply our solution for online segmentation and real-world segmentation, convincing segmentation results showing the practical ability of our work for real-world demonstrations.

cs.CV↗

arXiv2025

A Survey on Inference Optimization Techniques for Mixture of Experts Models

The emergence of large-scale Mixture of Experts (MoE) models represents a significant advancement in artificial intelligence, offering enhanced model capacity and computational efficiency through conditional computation. However, deploying and running inference on these models presents significant challenges in computational resources, latency, and energy efficiency. This comprehensive survey analyzes optimization techniques for MoE models across the entire system stack. We first establish a taxonomical framework that categorizes optimization approaches into model-level, system-level, and hardware-level optimizations. At the model level, we examine architectural innovations including efficient expert design, attention mechanisms, various compression techniques such as pruning, quantization, and knowledge distillation, as well as algorithm improvement including dynamic routing strategies and expert merging methods. At the system level, we investigate distributed computing approaches, load balancing mechanisms, and efficient scheduling algorithms that enable scalable deployment. Furthermore, we delve into hardware-specific optimizations and co-design strategies that maximize throughput and energy efficiency. This survey provides both a structured overview of existing solutions and identifies key challenges and promising research directions in MoE inference optimization. To facilitate ongoing updates and the sharing of cutting-edge advances in MoE inference optimization research, we have established a repository accessible at https://github.com/MoE-Inf/awesome-moe-inference/.

cs.LG↗

arXiv2025

Epicardium Prompt-guided Real-time Cardiac Ultrasound Frame-to-volume Registration

A comprehensive guidance view for cardiac interventional surgery can be provided by the real-time fusion of the intraoperative 2D images and preoperative 3D volume based on the ultrasound frame-to-volume registration. However, cardiac ultrasound images are characterized by a low signal-to-noise ratio and small differences between adjacent frames, coupled with significant dimension variations between 2D frames and 3D volumes to be registered, resulting in real-time and accurate cardiac ultrasound frame-to-volume registration being a very challenging task. This paper introduces a lightweight end-to-end Cardiac Ultrasound frame-to-volume Registration network, termed CU-Reg. Specifically, the proposed model leverages epicardium prompt-guided anatomical clues to reinforce the interaction of 2D sparse and 3D dense features, followed by a voxel-wise local-global aggregation of enhanced features, thereby boosting the cross-dimensional matching effectiveness of low-quality ultrasound modalities. We further embed an inter-frame discriminative regularization term within the hybrid supervised learning to increase the distinction between adjacent slices in the same ultrasound volume to ensure registration stability. Experimental results on the reprocessed CAMUS dataset demonstrate that our CU-Reg surpasses existing methods in terms of registration accuracy and efficiency, meeting the guidance requirements of clinical cardiac interventional surgery.

eess.IV↗

arXiv2025

Creating Virtual Environments with 3D Gaussian Splatting: A Comparative Study

3D Gaussian Splatting (3DGS) has recently emerged as an innovative and efficient 3D representation technique. While its potential for extended reality (XR) applications is frequently highlighted, its practical effectiveness remains underexplored. In this work, we examine three distinct 3DGS-based approaches for virtual environment (VE) creation, leveraging their unique strengths for efficient and visually compelling scene representation. By conducting a comparable study, we evaluate the feasibility of 3DGS in creating immersive VEs, identify its limitations in XR applications, and discuss future research and development opportunities.

cs.CV↗

arXiv2025

Towards an Information Theoretic Framework of Context-Based Offline Meta-Reinforcement Learning

As a marriage between offline RL and meta-RL, the advent of offline meta-reinforcement learning (OMRL) has shown great promise in enabling RL agents to multi-task and quickly adapt while acquiring knowledge safely. Among which, context-based OMRL (COMRL) as a popular paradigm, aims to learn a universal policy conditioned on effective task representations. In this work, by examining several key milestones in the field of COMRL, we propose to integrate these seemingly independent methodologies into a unified framework. Most importantly, we show that the pre-existing COMRL algorithms are essentially optimizing the same mutual information objective between the task variable $M$ and its latent representation $Z$ by implementing various approximate bounds. Such theoretical insight offers ample design freedom for novel algorithms. As demonstrations, we propose a supervised and a self-supervised implementation of $I(Z; M)$, and empirically show that the corresponding optimization algorithms exhibit remarkable generalization across a broad spectrum of RL benchmarks, context shift scenarios, data qualities and deep learning architectures. This work lays the information theoretic foundation for COMRL methods, leading to a better understanding of task representation learning in the context of reinforcement learning. Given its generality, we envision our framework as a promising offline pre-training paradigm of foundation models for decision making.

cs.LG↗

arXiv2024

Surgical Workflow Recognition and Blocking Effectiveness Detection in Laparoscopic Liver Resections with Pringle Maneuver

Pringle maneuver (PM) in laparoscopic liver resection aims to reduce blood loss and provide a clear surgical view by intermittently blocking blood inflow of the liver, whereas prolonged PM may cause ischemic injury. To comprehensively monitor this surgical procedure and provide timely warnings of ineffective and prolonged blocking, we suggest two complementary AI-assisted surgical monitoring tasks: workflow recognition and blocking effectiveness detection in liver resections. The former presents challenges in real-time capturing of short-term PM, while the latter involves the intraoperative discrimination of long-term liver ischemia states. To address these challenges, we meticulously collect a novel dataset, called PmLR50, consisting of 25,037 video frames covering various surgical phases from 50 laparoscopic liver resection procedures. Additionally, we develop an online baseline for PmLR50, termed PmNet. This model embraces Masked Temporal Encoding (MTE) and Compressed Sequence Modeling (CSM) for efficient short-term and long-term temporal information modeling, and embeds Contrastive Prototype Separation (CPS) to enhance action discrimination between similar intraoperative operations. Experimental results demonstrate that PmNet outperforms existing state-of-the-art surgical workflow recognition methods on the PmLR50 benchmark. Our research offers potential clinical applications for the laparoscopic liver surgery community. Codes are available at https://github.com/RascalGdd/PmNet.

cs.CV↗

arXiv2024

Advancing Extended Reality with 3D Gaussian Splatting: Innovations and Prospects

3D Gaussian Splatting (3DGS) has attracted significant attention for its potential to revolutionize 3D representation, rendering, and interaction. Despite the rapid growth of 3DGS research, its direct application to Extended Reality (XR) remains underexplored. Although many studies recognize the potential of 3DGS for XR, few have explicitly focused on or demonstrated its effectiveness within XR environments. In this paper, we aim to synthesize innovations in 3DGS that show specific potential for advancing XR research and development. We conduct a comprehensive review of publicly available 3DGS papers, with a focus on those referencing XR-related concepts. Additionally, we perform an in-depth analysis of innovations explicitly relevant to XR and propose a taxonomy to highlight their significance. Building on these insights, we propose several prospective XR research areas where 3DGS can make promising contributions, yet remain rarely touched. By investigating the intersection of 3DGS and XR, this paper provides a roadmap to push the boundaries of XR using cutting-edge 3DGS techniques.

cs.CV↗

arXiv2024

MS2Mesh-XR: Multi-modal Sketch-to-Mesh Generation in XR Environments

We present MS2Mesh-XR, a novel multi-modal sketch-to-mesh generation pipeline that enables users to create realistic 3D objects in extended reality (XR) environments using hand-drawn sketches assisted by voice inputs. In specific, users can intuitively sketch objects using natural hand movements in mid-air within a virtual environment. By integrating voice inputs, we devise ControlNet to infer realistic images based on the drawn sketches and interpreted text prompts. Users can then review and select their preferred image, which is subsequently reconstructed into a detailed 3D mesh using the Convolutional Reconstruction Model. In particular, our proposed pipeline can generate a high-quality 3D mesh in less than 20 seconds, allowing for immersive visualization and manipulation in run-time XR scenes. We demonstrate the practicability of our pipeline through two use cases in XR settings. By leveraging natural user inputs and cutting-edge generative AI capabilities, our approach can significantly facilitate XR-based creative production and enhance user experiences. Our code and demo will be available at: https://yueqiu0911.github.io/MS2Mesh-XR/

cs.CV↗

arXiv2024

DEL-Ranking: Ranking-Correction Denoising Framework for Elucidating Molecular Affinities in DNA-Encoded Libraries

DNA-encoded library (DEL) screening has revolutionized the detection of protein-ligand interactions through read counts, enabling rapid exploration of vast chemical spaces. However, noise in read counts, stemming from nonspecific interactions, can mislead this exploration process. We present DEL-Ranking, a novel distribution-correction denoising framework that addresses these challenges. Our approach introduces two key innovations: (1) a novel ranking loss that rectifies relative magnitude relationships between read counts, enabling the learning of causal features determining activity levels, and (2) an iterative algorithm employing self-training and consistency loss to establish model coherence between activity label and read count predictions. Furthermore, we contribute three new DEL screening datasets, the first to comprehensively include multi-dimensional molecular representations, protein-ligand enrichment values, and their activity labels. These datasets mitigate data scarcity issues in AI-driven DEL screening research. Rigorous evaluation on diverse DEL datasets demonstrates DEL-Ranking's superior performance across multiple correlation metrics, with significant improvements in binding affinity prediction accuracy. Our model exhibits zero-shot generalization ability across different protein targets and successfully identifies potential motifs determining compound binding affinity. This work advances DEL screening analysis and provides valuable resources for future research in this area.

cs.LG↗

arXiv2024

Point Cloud Understanding via Attention-Driven Contrastive Learning

Recently Transformer-based models have advanced point cloud understanding by leveraging self-attention mechanisms, however, these methods often overlook latent information in less prominent regions, leading to increased sensitivity to perturbations and limited global comprehension. To solve this issue, we introduce PointACL, an attention-driven contrastive learning framework designed to address these limitations. Our method employs an attention-driven dynamic masking strategy that guides the model to focus on under-attended regions, enhancing the understanding of global structures within the point cloud. Then we combine the original pre-training loss with a contrastive learning loss, improving feature discrimination and generalization. Extensive experiments validate the effectiveness of PointACL, as it achieves state-of-the-art performance across a variety of 3D understanding tasks, including object classification, part segmentation, and few-shot learning. Specifically, when integrated with different Transformer backbones like Point-MAE and PointGPT, PointACL demonstrates improved performance on datasets such as ScanObjectNN, ModelNet40, and ShapeNetPart. This highlights its superior capability in capturing both global and local features, as well as its enhanced robustness against perturbations and incomplete data.

cs.CV↗

arXiv2024

HOBBIT: A Mixed Precision Expert Offloading System for Fast MoE Inference

The Mixture-of-Experts (MoE) architecture has demonstrated significant advantages in the era of Large Language Models (LLMs), offering enhanced capabilities with reduced inference costs. However, deploying MoE-based LLMs on memoryconstrained edge devices remains challenging due to their substantial memory requirements. While existing expertoffloading methods alleviate the memory requirements, they often incur significant expert-loading costs or compromise model accuracy. We present HOBBIT, a mixed precision expert offloading system to enable flexible and efficient MoE inference. Our key insight is that dynamically replacing less critical cache-miss experts with low precision versions can substantially reduce expert-loading latency while preserving model accuracy. HOBBIT introduces three innovative techniques that map the natural hierarchy of MoE computation: (1) a token-level dynamic expert loading mechanism, (2) a layer-level adaptive expert prefetching technique, and (3) a sequence-level multidimensional expert caching policy. These innovations fully leverage the benefits of mixedprecision expert inference. By implementing HOBBIT on top of the renowned LLM inference framework Llama.cpp, we evaluate its performance across different edge devices with representative MoE models. The results demonstrate that HOBBIT achieves up to a 9.93x speedup in decoding compared to state-of-the-art MoE offloading systems.

cs.LG↗

arXiv2024

LLM-Assisted Multi-Teacher Continual Learning for Visual Question Answering in Robotic Surgery

Visual question answering (VQA) is crucial for promoting surgical education. In practice, the needs of trainees are constantly evolving, such as learning more surgical types, adapting to different robots, and learning new surgical instruments and techniques for various surgeries. However, patient data privacy often restricts the availability of old data when updating the model, necessitating an exemplar-free continual learning (CL) setup. Prior CL studies overlooked two vital problems in the surgical domain: 1) large domain shifts from diverse surgical operations collected from multiple sources, and 2) severe data imbalance arising from the uneven presence of surgical instruments or activities. This paper proposes addressing these problems with a multimodal large language model (LLM) and an adaptive weight assignment methodology. We first develop a new multi-teacher CL framework that leverages a multimodal LLM as the additional teacher. The strong generalization ability of the LLM can bridge the knowledge gap when domain shifts and data imbalances occur. We then put forth a novel data processing method that transforms complex LLM embeddings into logits compatible with our CL framework. We further design an adaptive weight assignment approach that balances the generalization ability of the LLM and the domain expertise of the old CL model. Finally, to comprehensively test the effectiveness of our proposed method, we have also constructed two new surgical VQA datasets that are largely different from existing ones and could be valuable resources for future research. Extensive experimental results on the tested datasets demonstrate the superiority of our method to other advanced CL schemes.

cs.IR↗