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Philip Schniter

Publications and source records attributed to Philip Schniter.

At least 19 recordsLinked to original sources

Patch-Based Diffusion Reconstruction for Accelerated Cardiac Cine

Purpose: To develop and evaluate a diffusion-based reconstruction framework for highly accelerated 2D real-time (RT) cine cardiovascular magnetic resonance imaging (CMR). Methods: We trained an unconditional patch-based diffusion model and incorporated it into a reconstruction framework, termed CineDiff, using diffusion posterior sampling for data consistency. CineDiff was evaluated in four settings: (i) 30 retrospectively undersampled breath-held cine at 1.5T and 3T from healthy participants across multiple acceleration rates, (ii) 15 prospectively undersampled free-breathing RT cine at 1.5T and 3T from patients indicated for clinical CMR, and (iii) 10 prospectively undersampled mid-field (0.55T) free-breathing scans, including five from healthy subjects and five from porcine models. For retrospective undersampling, reconstruction quality was assessed using peak signal-to-noise ratio (PSNR), structural similarity index measure (SSIM), learned perceptual image patch similarity (LPIPS), and deep image structure and texture similarity (DISTS). For prospective undersampling, image quality was evaluated by blinded expert scoring on a 5-point Likert scale. Results: In retrospectively undersampled breath-held cine data, CineDiff achieved higher PSNR and SSIM and lower LPIPS and DISTS than the comparison methods across all evaluated acceleration rates. In prospectively undersampled free-breathing RT cine data, CineDiff received higher expert image-quality scores. Qualitatively, CineDiff reduced block-like artifacts and preserved finer anatomical detail compared with traditional compressed sensing and a variational network method, termed CineVN. Conclusion: CineDiff enabled high-quality reconstruction of highly accelerated 2D RT cine CMR. The method also demonstrated robustness to out-of-distribution data, including mid-field and porcine acquisitions.

eess.IV

Minimax Multi-Target Conformal Prediction with Applications to Imaging Inverse Problems

In ill-posed imaging inverse problems, uncertainty quantification remains a fundamental challenge, especially in safety-critical applications. Recently, conformal prediction has been used to quantify the uncertainty that the inverse problem contributes to downstream tasks like image classification, image quality assessment, fat mass quantification, etc. While existing works handle only a scalar estimation target, practical applications often involve multiple targets. In response, we propose an asymptotically minimax approach to multi-target conformal prediction that provides tight prediction intervals while ensuring joint marginal coverage. We then outline how our minimax approach can be applied to multi-metric blind image quality assessment, multi-task uncertainty quantification, and multi-round measurement acquisition. Finally, we numerically demonstrate the benefits of our minimax method, relative to existing multi-target conformal prediction methods, using both synthetic and magnetic resonance imaging (MRI) data. Code is available at https://github.com/jwen307/multi_target_minimax.

cs.CV

Conformal Bounds on Full-Reference Image Quality for Imaging Inverse Problems

In imaging inverse problems, we would like to know how close the recovered image is to the true image in terms of full-reference image quality (FRIQ) metrics like PSNR, SSIM, LPIPS, etc. This is especially important in safety-critical applications like medical imaging, where knowing that, say, the SSIM was poor could potentially avoid a costly misdiagnosis. But since we don't know the true image, computing FRIQ is non-trivial. In this work, we combine conformal prediction with approximate posterior sampling to construct bounds on FRIQ that are guaranteed to hold up to a user-specified error probability. We demonstrate our approach on image denoising and accelerated magnetic resonance imaging (MRI) problems. Code is available at https://github.com/jwen307/quality_uq.

cs.CV

Solving Inverse Problems using Diffusion with Iterative Colored Renoising

Imaging inverse problems can be solved in an unsupervised manner using pre-trained diffusion models, but doing so requires approximating the gradient of the measurement-conditional score function in the diffusion reverse process. We show that the approximations produced by existing methods are relatively poor, especially early in the reverse process, and so we propose a new approach that iteratively reestimates and "renoises" the estimate several times per diffusion step. This iterative approach, which we call Fast Iterative REnoising (FIRE), injects colored noise that is shaped to ensure that the pre-trained diffusion model always sees white noise, in accordance with how it was trained. We then embed FIRE into the DDIM reverse process and show that the resulting "DDfire" offers state-of-the-art accuracy and runtime on several linear inverse problems, as well as phase retrieval. Our implementation is at https://github.com/matt-bendel/DDfire

cs.CV

Score Combining for Contrastive OOD Detection

In out-of-distribution (OOD) detection, one is asked to classify whether a test sample comes from a known inlier distribution or not. We focus on the case where the inlier distribution is defined by a training dataset and there exists no additional knowledge about the novelties that one is likely to encounter. This problem is also referred to as novelty detection, one-class classification, and unsupervised anomaly detection. The current literature suggests that contrastive learning techniques are state-of-the-art for OOD detection. We aim to improve on those techniques by combining/ensembling their scores using the framework of null hypothesis testing and, in particular, a novel generalized likelihood ratio test (GLRT). We demonstrate that our proposed GLRT-based technique outperforms the state-of-the-art CSI and SupCSI techniques from Tack et al. 2020 in dataset-vs-dataset experiments with CIFAR-10, SVHN, LSUN, ImageNet, and CIFAR-100, as well as leave-one-class-out experiments with CIFAR-10. We also demonstrate that our GLRT outperforms the score-combining methods of Fisher, Bonferroni, Simes, Benjamini-Hochwald, and Stouffer in our application.

cs.LG

pcaGAN: Improving Posterior-Sampling cGANs via Principal Component Regularization

In ill-posed imaging inverse problems, there can exist many hypotheses that fit both the observed measurements and prior knowledge of the true image. Rather than returning just one hypothesis of that image, posterior samplers aim to explore the full solution space by generating many probable hypotheses, which can later be used to quantify uncertainty or construct recoveries that appropriately navigate the perception/distortion trade-off. In this work, we propose a fast and accurate posterior-sampling conditional generative adversarial network (cGAN) that, through a novel form of regularization, aims for correctness in the posterior mean as well as the trace and K principal components of the posterior covariance matrix. Numerical experiments demonstrate that our method outperforms contemporary cGANs and diffusion models in imaging inverse problems like denoising, large-scale inpainting, and accelerated MRI recovery. The code for our model can be found here: https://github.com/matt-bendel/pcaGAN.

eess.IV

Groupwise Image Registration with Edge-Based Loss for Low-SNR Cardiac MRI

Purpose: To perform image registration and averaging of multiple free-breathing single-shot cardiac images, where the individual images may have a low signal-to-noise ratio (SNR). Methods: To address low SNR encountered in single-shot imaging, especially at low field strengths, we propose a fast deep learning (DL)-based image registration method, called Averaging Morph with Edge Detection (AiM-ED). AiM-ED jointly registers multiple noisy source images to a noisy target image and utilizes a noise-robust pre-trained edge detector to define the training loss. We validate AiM-ED using synthetic late gadolinium enhanced (LGE) images from the MR extended cardiac-torso (MRXCAT) phantom and free-breathing single-shot LGE images from healthy subjects (24 slices) and patients (5 slices) under various levels of added noise. Additionally, we demonstrate the clinical feasibility of AiM-ED by applying it to data from patients (6 slices) scanned on a 0.55T scanner. Results: Compared to a traditional energy-minimization-based image registration method and DL-based VoxelMorph, images registered using AiM-ED exhibit higher values of recovery SNR and three perceptual image quality metrics. An ablation study shows the benefit of both jointly processing multiple source images and using an edge map in AiM-ED. Conclusion: For single-shot LGE imaging, AiM-ED outperforms existing image registration methods in terms of image quality. With fast inference, minimal training data requirements, and robust performance at various noise levels, AiM-ED has the potential to benefit single-shot CMR applications.

eess.IV

Fast and Robust Phase Retrieval via Deep Expectation-Consistent Approximation

Accurately recovering images from phaseless measurements is a challenging and long-standing problem. In this work, we present "deepECpr," which combines expectation-consistent (EC) approximation with deep denoising networks to surpass state-of-the-art phase-retrieval methods in both speed and accuracy. In addition to applying EC in a non-traditional manner, deepECpr includes a novel stochastic damping scheme that is inspired by recent diffusion methods. Like existing phase-retrieval methods based on plug-and-play priors, regularization by denoising, or diffusion, deepECpr iterates a denoising stage with a measurement-exploitation stage. But unlike existing methods, deepECpr requires far fewer denoiser calls. We compare deepECpr to the state-of-the-art prDeep (Metzler et al., 2018), Deep-ITA (Wang et al., 2020), DOLPH (Shoushtari et al., 2023), and Diffusion Posterior Sampling (Chung et al., 2023) methods for noisy phase-retrieval of color, natural, and unnatural grayscale images on oversampled-Fourier and coded-diffraction-pattern measurements and find improvements in both PSNR and SSIM with significantly fewer denoiser calls.

cs.CV

Task-Driven Uncertainty Quantification in Inverse Problems via Conformal Prediction

In imaging inverse problems, one seeks to recover an image from missing/corrupted measurements. Because such problems are ill-posed, there is great motivation to quantify the uncertainty induced by the measurement-and-recovery process. Motivated by applications where the recovered image is used for a downstream task, such as soft-output classification, we propose a task-centered approach to uncertainty quantification. In particular, we use conformal prediction to construct an interval that is guaranteed to contain the task output from the true image up to a user-specified probability, and we use the width of that interval to quantify the uncertainty contributed by measurement-and-recovery. For posterior-sampling-based image recovery, we construct locally adaptive prediction intervals. Furthermore, we propose to collect measurements over multiple rounds, stopping as soon as the task uncertainty falls below an acceptable level. We demonstrate our methodology on accelerated magnetic resonance imaging (MRI): https://github.com/jwen307/TaskUQ.

cs.CV

Surface Coil Intensity Correction for MRI

Modern MRI scanners utilize one or more arrays of small receive-only coils to collect k-space data. The sensitivity maps of the coils, when estimated using traditional methods, differ from the true sensitivity maps, which are generally unknown. Consequently, the reconstructed MR images exhibit undesired spatial variation in intensity. These intensity variations can be at least partially corrected using pre-scan data. In this work, we propose an intensity correction method that utilizes pre-scan data. For demonstration, we apply our method to a digital phantom, as well as to cardiac MRI data collected on a commercial scanner by Siemens Healthineers. The code is available at https://github.com/OSU-MR/SCC.

eess.IV

A Regularized Conditional GAN for Posterior Sampling in Image Recovery Problems

In image recovery problems, one seeks to infer an image from distorted, incomplete, and/or noise-corrupted measurements. Such problems arise in magnetic resonance imaging (MRI), computed tomography, deblurring, super-resolution, inpainting, phase retrieval, image-to-image translation, and other applications. Given a training set of signal/measurement pairs, we seek to do more than just produce one good image estimate. Rather, we aim to rapidly and accurately sample from the posterior distribution. To do this, we propose a regularized conditional Wasserstein GAN that generates dozens of high-quality posterior samples per second. Our regularization comprises an $\ell_1$ penalty and an adaptively weighted standard-deviation reward. Using quantitative evaluation metrics like conditional Fréchet inception distance, we demonstrate that our method produces state-of-the-art posterior samples in both multicoil MRI and large-scale inpainting applications. The code for our model can be found here: https://github.com/matt-bendel/rcGAN

cs.CV

A Conditional Normalizing Flow for Accelerated Multi-Coil MR Imaging

Accelerated magnetic resonance (MR) imaging attempts to reduce acquisition time by collecting data below the Nyquist rate. As an ill-posed inverse problem, many plausible solutions exist, yet the majority of deep learning approaches generate only a single solution. We instead focus on sampling from the posterior distribution, which provides more comprehensive information for downstream inference tasks. To do this, we design a novel conditional normalizing flow (CNF) that infers the signal component in the measurement operator's nullspace, which is later combined with measured data to form complete images. Using fastMRI brain and knee data, we demonstrate fast inference and accuracy that surpasses recent posterior sampling techniques for MRI. Code is available at https://github.com/jwen307/mri_cnf/

eess.IV

MRI Recovery with Self-Calibrated Denoisers without Fully-Sampled Data

Objective: Acquiring fully sampled training data is challenging for many MRI applications. We present a self-supervised image reconstruction method, termed ReSiDe, capable of recovering images solely from undersampled data. Materials and Methods: ReSiDe is inspired by plug-and-play (PnP) methods, but unlike traditional PnP approaches that utilize pre-trained denoisers, ReSiDe iteratively trains the denoiser on the image or images that are being reconstructed. We introduce two variations of our method: ReSiDe-S and ReSiDe-M. ReSiDe-S is scan-specific and works with a single set of undersampled measurements, while ReSiDe-M operates on multiple sets of undersampled measurements and provides faster inference. Studies I, II, and III compare ReSiDe-S and ReSiDe-M against other self-supervised or unsupervised methods using data from T1- and T2-weighted brain MRI, MRXCAT digital perfusion phantom, and first-pass cardiac perfusion, respectively. Results: ReSiDe-S and ReSiDe-M outperform other methods in terms of peak signal-to-noise ratio and structural similarity index measure for Studies I and II, and in terms of expert scoring for Study III. Discussion: We present a self-supervised image reconstruction method and validate it in both static and dynamic MRI applications. These developments can benefit MRI applications where the availability of fully sampled training data is limited.

eess.IV

Denoising Generalized Expectation-Consistent Approximation for MR Image Recovery

To solve inverse problems, plug-and-play (PnP) methods replace the proximal step in a convex optimization algorithm with a call to an application-specific denoiser, often implemented using a deep neural network (DNN). Although such methods yield accurate solutions, they can be improved. For example, denoisers are usually designed/trained to remove white Gaussian noise, but the denoiser input error in PnP algorithms is usually far from white or Gaussian. Approximate message passing (AMP) methods provide white and Gaussian denoiser input error, but only when the forward operator is sufficiently random. In this work, for Fourier-based forward operators, we propose a PnP algorithm based on generalized expectation-consistent (GEC) approximation -- a close cousin of AMP -- that offers predictable error statistics at each iteration, as well as a new DNN denoiser that leverages those statistics. We apply our approach to magnetic resonance (MR) image recovery and demonstrate its advantages over existing PnP and AMP methods.

eess.IV

Expectation Consistent Plug-and-Play for MRI

For image recovery problems, plug-and-play (PnP) methods have been developed that replace the proximal step in an optimization algorithm with a call to an application-specific denoiser, often implemented using a deep neural network. Although such methods have been successful, they can be improved. For example, the denoiser is often trained using white Gaussian noise, while PnP's denoiser input error is often far from white and Gaussian, with statistics that are difficult to predict from iteration to iteration. PnP methods based on approximate message passing (AMP) are an exception, but only when the forward operator behaves like a large random matrix. In this work, we design a PnP method using the expectation consistent (EC) approximation algorithm, a generalization of AMP, that offers predictable error statistics at each iteration, from which a deep-net denoiser can be effectively trained.

cs.IT

Deep Neural Networks for Radar Waveform Classification

We consider the problem of classifying radar pulses given raw I/Q waveforms in the presence of noise and absence of synchronization. We also consider the problem of classifying multiple superimposed radar pulses. For both, we design deep neural networks (DNNs) that are robust to synchronization, pulse width, and SNR. Our designs yield more than 100x reduction in error-rate over the previous state-of-the-art.

cs.LG

MRI Recovery with A Self-calibrated Denoiser

Plug-and-play (PnP) methods that employ application-specific denoisers have been proposed to solve inverse problems, including MRI reconstruction. However, training application-specific denoisers is not feasible for many applications due to the lack of training data. In this work, we propose a PnP-inspired recovery method that does not require data beyond the single, incomplete set of measurements. The proposed method, called recovery with a self-calibrated denoiser (ReSiDe), trains the denoiser from the patches of the image being recovered. The denoiser training and a call to the denoising subroutine are performed in each iteration of a PnP algorithm, leading to a progressive refinement of the reconstructed image. For validation, we compare ReSiDe with a compressed sensing-based method and a PnP method with BM3D denoising using single-coil MRI brain data.

eess.IV

Sketching Datasets for Large-Scale Learning (long version)

This article considers "compressive learning," an approach to large-scale machine learning where datasets are massively compressed before learning (e.g., clustering, classification, or regression) is performed. In particular, a "sketch" is first constructed by computing carefully chosen nonlinear random features (e.g., random Fourier features) and averaging them over the whole dataset. Parameters are then learned from the sketch, without access to the original dataset. This article surveys the current state-of-the-art in compressive learning, including the main concepts and algorithms, their connections with established signal-processing methods, existing theoretical guarantees -- on both information preservation and privacy preservation, and important open problems.

stat.ML