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Philipp D. Lösel

Publications and source records attributed to Philipp D. Lösel.

2 recordsLinked to original sources

Clinical application of HEDI for biomechanical evaluation and visualisation in incisional hernia repair

Background: Abdominal wall defects, such as incisional hernias, are a common source of pain and discomfort and often require repeated surgical interventions. Traditional mesh repair techniques typically rely on fixed overlap based on defect size, without considering important biomechanical factors like muscle activity, internal pressure, and tissue elasticity. This study aims to introduce a biomechanical approach to incisional hernia repair that accounts for abdominal wall instability and to evaluate a visualisation tool designed to support surgical planning. Methods: We developed HEDI, a tool that uses computed tomography with Valsalva maneuver to automatically assess hernia size, volume, and abdominal wall instability. This tool was applied in the preoperative evaluation of 31 patients undergoing incisional hernia repair. Surgeries were performed concurrently with the development of the tool, and patient outcomes were monitored over a three-year period. Results: Here we show that all 31 patients remain free of pain and hernia recurrence three years after surgery. The tool provides valuable visual insights into abdominal wall dynamics, supporting surgical decision-making. However, it should be used as an adjunct rather than a standalone guide. Conclusions: This study presents a biomechanical strategy for hernia repair and introduces a visualisation tool that enhances preoperative assessment. While early results are promising, the tool's evolving nature and its role as a visual aid should be considered when interpreting outcomes. Further research is needed to validate its broader clinical utility.

cs.CV↗

Self-Validated Learning for Particle Separation: A Correctness-Based Self-Training Framework Without Human Labels

Non-destructive 3D imaging of large multi-particulate samples is essential for quantifying particle-level properties, such as size, shape, and spatial distribution, across applications in mining, materials science, and geology. However, accurate instance segmentation of particles in tomographic data remains challenging due to high morphological variability and frequent particle contact, which limit the effectiveness of classical methods like watershed algorithms. While supervised deep learning approaches offer improved performance, they rely on extensive annotated datasets that are labor-intensive, error-prone, and difficult to scale. In this work, we propose self-validated learning, a novel self-training framework for particle instance segmentation that eliminates the need for manual annotations. Our method leverages implicit boundary detection and iteratively refines the training set by identifying particles that can be consistently matched across reshuffled scans of the same sample. This self-validation mechanism mitigates the impact of noisy pseudo-labels, enabling robust learning from unlabeled data. After just three iterations, our approach accurately segments over 97% of the total particle volume and identifies more than 54,000 individual particles in tomographic scans of quartz fragments. Importantly, the framework also enables fully autonomous model evaluation without the need for ground truth annotations, as confirmed through comparisons with state-of-the-art instance segmentation techniques. The method is integrated into the Biomedisa image analysis platform (https://github.com/biomedisa/biomedisa/).

eess.IV↗