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Pietro Grassi

Publications and source records attributed to Pietro Grassi.

4 recordsLinked to original sources

The Broken Shield of European Palliative Care: Evidence from Synthetic Counterfactuals on Financial Toxicity and Informal Care

The transition of end-of-life care to palliative care (PC) sparks intense debate: does it provide economic relief or shift unremunerated labor costs onto families? Evaluating this is hindered by causal inference challenges and skewed healthcare costs. To overcome these limitations, we introduce a Synthetic Data Generation framework. Using pan-European SHARE data (2016-2021), we deploy Tabular Denoising Diffusion Probabilistic Models within a Two-Learner architecture to synthesize high-fidelity digital twins. By including the 2020-2021 lockdowns, we leverage the COVID-19 pandemic to isolate structural inequalities from transient market shocks. Our findings challenge the strict cost-shifting hypothesis: on average, PC acts as a "double shield", truncating out-of-pocket expenditures (liquid toxicity) and informal caregiving shadow values (time poverty). However, quantile treatment models expose a "broken shield" for vulnerable households and severe tail events. Non-cancer trajectories drive massive structural penalties that escalate at the distribution's tail, mechanically compounded by physical dependency. Socio-demographics heavily modulate this exposure: lacking a spousal net inflates the burden, rigid gender dynamics trigger labor market ejection, and financial distress acts as a profound multiplier. Institutionally, high-wage Nordic regimes paradoxically impose opportunity costs, while severe penalties in underfunded Eastern systems-mediated by financial distress-drive families toward resource exhaustion. We conclude that while PC is an ethical imperative, its expansion must be decoupled from the oncological paradigm and matched with state-funded long-term care to protect against clinical decline and financial shocks.

stat.AP

Synthesizing the Counterfactual: A CTGAN-Augmented Causal Evaluation of Palliative Care on Spousal Depression

Spousal bereavement severely deteriorates mental health. While palliative care benefits dying patients, its "stress-buffering" effect on survivors' depression remains empirically elusive due to acute small-$N$ constraints in longitudinal dyadic data. This study evaluates the causal impact of palliative care on bereaved spouses while introducing Synthetic Data Generation (SDG) to resolve sample attrition in quasi-experimental designs. Using SHARE panel data, we augment the sparse treated cohort via a Conditional Tabular GAN, anchoring synthetic trajectories to empirical baseline constraints to preserve causal pathways. A Matched Difference-in-Differences estimator applied to the high-fidelity augmented dataset evaluates the treatment effect. Results reveal a non-linear psychological response. Palliative care initially exacerbates acute depressive symptoms at the time of loss ($\beta_0 = 0.218,\ p < 0.05$), reflecting the intense emotional confrontation of the intervention. However, a sustained stress-buffering effect emerges in subsequent periods ($\beta_2 = -0.763,\ p < 0.01$), indicating an accelerated long-term recovery compared to standard care. Estimates are highly robust to unobserved confounding (Oster's $\delta > 1$). Substantively, we advocate for reconceptualizing end-of-life care as a dyadic public health intervention. Methodologically, we establish SDG as a robust analytical tool capable of powering fragile quasi-experiments in longitudinal social surveys.

stat.AP

Approximation Properties of Evolutionary Dynamics in Continuous-Time Finite State Space Games

This thesis studies the convergence of finite-population stochastic evolutionary dynamics to their deterministic mean-field limit in continuous-time finite state space games. We first develop refined ergodic theorems for Markov chains with a single positive-recurrent class, guaranteeing the existence of a unique invariant distribution and almost-sure convergence of time averages. Next, we prove that the mean-field model, described by a system of Lipschitz-continuous ordinary differential equations, admits a unique solution that depends continuously on its initial condition and that constitutes the almost-sure limit for the empirical distributions with fixed policy. Furthermore, we show that every Mixed Stationary Nash Equilibrium of the mean-field game is approximated by a Nash equilibrium of the corresponding $N$-player game within an error $\epsilon$ for sufficiently large $N$. We finally demonstrate, by Kurtz's theorem, that the empirical state-policy distribution converges in probability to the mean-field trajectory. Numerical simulations conducted in MATLAB confirm the theoretical $\mathcal{O}(N^{-1/2})$ convergence rate in both models across a range of population sizes.

cs.GT

Enabling NLOS Imaging Capabilities at the Initial Access of 6G Base Stations

Sensing in non-line-of-sight (NLOS) is one of the major challenges for integrated sensing and communication systems. Existing countermeasures for NLOS either use prior knowledge on the environment to characterize all the multiple bounces or deploy anomalous reflectors in the environment to enable communication infrastructure to ''\textit{see behind the corner}''. This work addresses the integration of monostatic NLOS imaging functionalities into the initial access (IA) procedure of a next generation base station (BS), by means of a non-reconfigurable modular reflector. During standard-compliant IA, the BS sweeps a narrow beam using a pre-defined dedicated codebook to achieve the beam alignment with users. We introduce the imaging functionality by enhancing such codebook with imaging-specific entries that are jointly designed with the angular configuration of the modular reflector to enable high-resolution imaging of a region in NLOS by \textit{coherently} processing all the echoes at the BS. We derive closed-form expressions for the near-field (NF) spatial resolution, as well as for the \textit{effective aperture} (i.e., the portion of the reflector that actively contributes to improve image resolution). The problem of imaging of moving targets in NLOS is also addressed, and we propose a maximum-likelihood estimation for target's velocity in NF and related theoretical bound. Further, we discuss and quantify the inherent communication-imaging performance trade-offs and related system design challenges through numerical simulations. Finally, the proposed imaging method employing modular reflectors is validated both numerically and experimentally, showing the effectiveness of our concept.

eess.SP