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Pietro Lio'

Publications and source records attributed to Pietro Lio'.

24 records · Page 2Linked to original sources

Intra-City Urban Network and Traffic Flow Analysis from GPS Mobility Trace

We analyse two large-scale intra-city urban networks and traffic flows therein measured by GPS traces of taxis in San Francisco and Shanghai. Our results coincide with previous findings that, based purely on topological means, it is often insufficient to characterise traffic flow. Traditional shortest-path betweenness analysis, where shortest paths are calculated from each pairs of nodes, carries an unrealistic implicit assumption that each node or junction in the urban network generates and attracts an equal amount of traffic. We also argue that weighting edges based only on euclidean distance is inadequate, as primary roads are commonly favoured over secondary roads due to the perceived and actual travel time required. We show that betweenness traffic analysis can be improved by a simple extended framework which incorporates both the notions of node weights and fastest-path betweenness. We demonstrate that the framework is superior to traditional methods based solely on simple topological perspectives.

physics.soc-ph↗

Towards real-time community detection in large networks

The recent boom of large-scale Online Social Networks (OSNs) both enables and necessitates the use of parallelisable and scalable computational techniques for their analysis. We examine the problem of real-time community detection and a recently proposed linear time - O(m) on a network with m edges - label propagation or "epidemic" community detection algorithm. We identify characteristics and drawbacks of the algorithm and extend it by incorporating different heuristics to facilitate reliable and multifunctional real-time community detection. With limited computational resources, we employ the algorithm on OSN data with 1 million nodes and about 58 million directed edges. Experiments and benchmarks reveal that the extended algorithm is not only faster but its community detection accuracy is compared favourably over popular modularity-gain optimization algorithms known to suffer from their resolution limits.

physics.soc-ph↗

Human Heuristics for Autonomous Agents

We investigate the problem of autonomous agents processing pieces of information that may be corrupted (tainted). Agents have the option of contacting a central database for a reliable check of the status of the message, but this procedure is costly and therefore should be used with parsimony. Agents have to evaluate the risk of being infected, and decide if and when communicating partners are affordable. Trustability is implemented as a personal (one-to-one) record of past contacts among agents, and as a mean-field monitoring of the level of message corruption. Moreover, this information is slowly forgotten in time, so that at the end everybody is checked against the database. We explore the behavior of a homogeneous system in the case of a fixed pool of spreaders of corrupted messages, and in the case of spontaneous appearance of corrupted messages.

cs.MA↗

The influence of risk perception in epidemics: a cellular agent model

Our work stems from the consideration that the spreading of a disease is modulated by the individual's perception of the infected neighborhood and his/her strategy to avoid being infected as well. We introduced a general ``cellular agent'' model that accounts for a hetereogeneous and variable network of connections. The probability of infection is assumed to depend on the perception that an individual has about the spreading of the disease in her local neighborhood and on broadcasting media. In the one-dimensional homogeneous case the model reduces to the DK one, while for long-range coupling the dynamics exhibits large fluctuations that may lead to the complete extinction of the disease.

q-bio.PE↗

Modeling viral coevolution: HIV multi-clonal persistence and competition dynamics

The coexistence of different viral strains (quasispecies) within the same host are nowadays observed for a growing number of viruses, most notably HIV, Marburg and Ebola, but the conditions for the formation and survival of new strains have not yet been understood. We present a model of HIV quasispecies competition, that describes the conditions of viral quasispecies coexistence under different immune system conditions. Our model incorporates both T and B cells responses, and we show that the role of B cells is important and additive to that of T cells. Simulations of coinfection (simultaneous infection) and superinfection (delayed secondary infection) scenarios in the early stages (days) and in the late stages of the infection (years) are in agreement with emerging molecular biology findings. The immune response induces a competition among similar phenotypes, leading to differentiation (quasi-speciation), escape dynamics and complex oscillations of viral strain abundance. We found that the quasispecies dynamics after superinfection or coinfection has time scales of several months and becomes even slower when the immune system response is weak. Our model represents a general framework to study the speed and distribution of HIV quasispecies during disease progression, vaccination and therapy.

q-bio.PE↗

Selection, Mutations and Codon Usage in Bacterial Model

We present a statistical model of bacterial evolution based on the coupling between codon usage and tRNA abundance. Such a model interprets this aspect of the evolutionary process as a balance between the codon homogenization effect due to mutation process and the improvement of the translation phase due to natural selection. We develop a thermodynamical description of the asymptotic state of the model. The analysis of naturally occurring sequences shows that the effect of natural selection on codon bias not only affects genes whose products are largely required at maximal growth rate conditions but also gene products that undergo rapid transient increases.

cond-mat.stat-mech↗