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Ping Liang

Publications and source records attributed to Ping Liang.

14 recordsLinked to original sources

MVis-Fold: A Three-Dimensional Microvascular Structure Inference Model for Super-Resolution Ultrasound

Super-resolution ultrasound (SRUS) technology has overcome the resolution limitations of conventional ultrasound, enabling micrometer-scale imaging of microvasculature. However, due to the nature of imaging principles, three-dimensional reconstruction of microvasculature from SRUS remains an open challenge. We developed microvascular visualization fold (MVis-Fold), an innovative three-dimensional microvascular reconstruction model that integrates a cross-scale network architecture. This model can perform high-fidelity inference and reconstruction of three-dimensional microvascular networks from two-dimensional SRUS images. It precisely calculates key parameters in three-dimensional space that traditional two-dimensional SRUS cannot readily obtain. We validated the model's accuracy and reliability in three-dimensional microvascular reconstruction of solid tumors. This study establishes a foundation for three-dimensional quantitative analysis of microvasculature. It provides new tools and methods for diagnosis and monitoring of various diseases.

cs.CV

Uncertainty principles for free metaplectic transformation and associated metaplectic operators

In this paper, we systematically investigate the Heisenberg-Pauli-Weyl uncertainty principle for free metaplectic transformation, as well as metaplectic operators. Specifically, we obtain two different types of the uncertainty principle for free metaplectic transformations in terms of the so-called phase derivative, one of which can be generalized to the $L^p$-case with $1\le p\le 2$. The obtained results are valid not only for free metaplectic transformations but also for general metaplectic operators. In particular, we point out that our results are closely related to those given in \cite{Dias-deGosson-Prata}, and the relationship should be new and not exactly given in the existing literature.

math.FA

GenDMR: A dynamic multimodal role-swapping network for identifying risk gene phenotypes

Recent studies have shown that integrating multimodal data fusion techniques for imaging and genetic features is beneficial for the etiological analysis and predictive diagnosis of Alzheimer's disease (AD). However, there are several critical flaws in current deep learning methods. Firstly, there has been insufficient discussion and exploration regarding the selection and encoding of genetic information. Secondly, due to the significantly superior classification value of AD imaging features compared to genetic features, many studies in multimodal fusion emphasize the strengths of imaging features, actively mitigating the influence of weaker features, thereby diminishing the learning of the unique value of genetic features. To address this issue, this study proposes the dynamic multimodal role-swapping network (GenDMR). In GenDMR, we develop a novel approach to encode the spatial organization of single nucleotide polymorphisms (SNPs), enhancing the representation of their genomic context. Additionally, to adaptively quantify the disease risk of SNPs and brain region, we propose a multi-instance attention module to enhance model interpretability. Furthermore, we introduce a dominant modality selection module and a contrastive self-distillation module, combining them to achieve a dynamic teacher-student role exchange mechanism based on dominant and auxiliary modalities for bidirectional co-updating of different modal data. Finally, GenDMR achieves state-of-the-art performance on the ADNI public dataset and visualizes attention to different SNPs, focusing on confirming 12 potential high-risk genes related to AD, including the most classic APOE and recently highlighted significant risk genes. This demonstrates GenDMR's interpretable analytical capability in exploring AD genetic features, providing new insights and perspectives for the development of multimodal data fusion techniques.

q-bio.GN

Multi-SIGATnet: A multimodal schizophrenia MRI classification algorithm using sparse interaction mechanisms and graph attention networks

Schizophrenia is a serious psychiatric disorder. Its pathogenesis is not completely clear, making it difficult to treat patients precisely. Because of the complicated non-Euclidean network structure of the human brain, learning critical information from brain networks remains difficult. To effectively capture the topological information of brain neural networks, a novel multimodal graph attention network based on sparse interaction mechanism (Multi-SIGATnet) was proposed for SZ classification was proposed for SZ classification. Firstly, structural and functional information were fused into multimodal data to obtain more comprehensive and abundant features for patients with SZ. Subsequently, a sparse interaction mechanism was proposed to effectively extract salient features and enhance the feature representation capability. By enhancing the strong connections and weakening the weak connections between feature information based on an asymmetric convolutional network, high-order interactive features were captured. Moreover, sparse learning strategies were designed to filter out redundant connections to improve model performance. Finally, local and global features were updated in accordance with the topological features and connection weight constraints of the higher-order brain network, the features being projected to the classification target space for disorder classification. The effectiveness of the model is verified on the Center for Biomedical Research Excellence (COBRE) and University of California Los Angeles (UCLA) datasets, achieving 81.9\% and 75.8\% average accuracy, respectively, 4.6\% and 5.5\% higher than the graph attention network (GAT) method. Experiments showed that the Multi-SIGATnet method exhibited good performance in identifying SZ.

cs.CV

AI-Generated Content Enhanced Computer-Aided Diagnosis Model for Thyroid Nodules: A ChatGPT-Style Assistant

An artificial intelligence-generated content-enhanced computer-aided diagnosis (AIGC-CAD) model, designated as ThyGPT, has been developed. This model, inspired by the architecture of ChatGPT, could assist radiologists in assessing the risk of thyroid nodules through semantic-level human-machine interaction. A dataset comprising 19,165 thyroid nodule ultrasound cases from Zhejiang Cancer Hospital was assembled to facilitate the training and validation of the model. After training, ThyGPT could automatically evaluate thyroid nodule and engage in effective communication with physicians through human-computer interaction. The performance of ThyGPT was rigorously quantified using established metrics such as the receiver operating characteristic (ROC) curve, area under the curve (AUC), sensitivity, and specificity. The empirical findings revealed that radiologists, when supplemented with ThyGPT, markedly surpassed the diagnostic acumen of their peers utilizing traditional methods as well as the performance of the model in isolation. These findings suggest that AIGC-CAD systems, exemplified by ThyGPT, hold the promise to fundamentally transform the diagnostic workflows of radiologists in forthcoming years.

cs.CV

Automatic nodule identification and differentiation in ultrasound videos to facilitate per-nodule examination

Ultrasound is a vital diagnostic technique in health screening, with the advantages of non-invasive, cost-effective, and radiation free, and therefore is widely applied in the diagnosis of nodules. However, it relies heavily on the expertise and clinical experience of the sonographer. In ultrasound images, a single nodule might present heterogeneous appearances in different cross-sectional views which makes it hard to perform per-nodule examination. Sonographers usually discriminate different nodules by examining the nodule features and the surrounding structures like gland and duct, which is cumbersome and time-consuming. To address this problem, we collected hundreds of breast ultrasound videos and built a nodule reidentification system that consists of two parts: an extractor based on the deep learning model that can extract feature vectors from the input video clips and a real-time clustering algorithm that automatically groups feature vectors by nodules. The system obtains satisfactory results and exhibits the capability to differentiate ultrasound videos. As far as we know, it's the first attempt to apply re-identification technique in the ultrasonic field.

eess.IV

Edge-aware Hard Clustering Graph Pooling for Brain Imaging

Graph Convolutional Networks (GCNs) can capture non-Euclidean spatial dependence between different brain regions. The graph pooling operator, a crucial element of GCNs, enhances the representation learning capability and facilitates the acquisition of abnormal brain maps. However, most existing research designs graph pooling operators solely from the perspective of nodes while disregarding the original edge features. This confines graph pooling application scenarios and diminishes its ability to capture critical substructures. In this paper, we propose a novel edge-aware hard clustering graph pool (EHCPool), which is tailored to dominant edge features and redefines the clustering process. EHCPool initially introduced the 'Edge-to-Node' score criterion which utilized edge information to evaluate the significance of nodes. An innovative Iteration n-top strategy was then developed, guided by edge scores, to adaptively learn sparse hard clustering assignments for graphs. Additionally, a N-E Aggregation strategy is designed to aggregate node and edge features in each independent subgraph. Extensive experiments on the multi-site public datasets demonstrate the superiority and robustness of the proposed model. More notably, EHCPool has the potential to probe different types of dysfunctional brain networks from a data-driven perspective. Method code: https://github.com/swfen/EHCPool

cs.CV

Observation of unusual optical band structure of CH3NH3PbI3 perovskite single crystal

Extensive efforts have been undertaken on the photoelectric physics of hybrid organolead halide perovskites to unveil the reason for the attractive photovoltaic performance. Yet, the resulting evidences are far from being fully conclusive. Herein, we provide another direct support for this issue. In addition to the observation on the conventional band edge at 1.58 eV that presents a blueshift toward temperature increase, interestingly, we also observe an unusual optical band edge at 1.48 eV in CH3NH3PbI3 perovskite single crystals. Contrary to the conventional band edge, this one shows an obvious redshift toward the enhancement in temperature, in agreement with the Varshni relation. More interestingly, the unusual band edge exhibits a series of obvious absorption and photocurrent signals, but the according photoluminescence signals are not observable. This indicates that this band edge is particularly beneficial for the photovoltaic effect due to the inhibited radiative recombination. The kinetics on photo-involved charge transition and transfer are investigated using the pump-probe photoconductivity technique, and a changeable band structure model was proposed.

cond-mat.mtrl-sci

A Novel Hybrid Beamforming Algorithm with Unified Analog Beamforming by Subspace Construction Based on Partial CSI for Massive MIMO-OFDM Systems

Hybrid beamforming (HB) has been widely studied for reducing the number of costly radio frequency (RF) chains in massive multiple-input multiple-output (MIMO) systems. However, previous works on HB are limited to a single user equipment (UE) or a single group of UEs, employing the frequency-flat first-level analog beamforming (AB) that cannot be applied to multiple groups of UEs served in different frequency resources in an orthogonal frequency-division multiplexing (OFDM) system. In this paper, a novel HB algorithm with unified AB based on the spatial covariance matrix (SCM) knowledge of all UEs is proposed for a massive MIMO-OFDM system in order to support multiple groups of UEs. The proposed HB method with a much smaller number of RF chains can achieve more than 95% performance of full digital beamforming. In addition, a novel practical subspace construction (SC) algorithm based on partial channel state information is proposed to estimate the required SCM. The proposed SC method can offer more than 97% performance of the perfect SCM case. With the proposed methods, significant cost and power savings can be achieved without large loss in performance. Furthermore, the proposed methods can be applied to massive MIMO-OFDM systems in both time-division duplex and frequency-division duplex.

cs.IT

On the Matrix Inversion Approximation Based on Neumann Series in Massive MIMO Systems

Zero-Forcing (ZF) has been considered as one of the potential practical precoding and detection method for massive MIMO systems. One of the most important advantages of massive MIMO is the capability of supporting a large number of users in the same time-frequency resource, which requires much larger dimensions of matrix inversion for ZF than conventional multi-user MIMO systems. In this case, Neumann Series (NS) has been considered for the Matrix Inversion Approximation (MIA), because of its suitability for massive MIMO systems and its advantages in hardware implementation. The performance-complexity trade-off and the hardware implementation of NS-based MIA in massive MIMO systems have been discussed. In this paper, we analyze the effects of the ratio of the number of massive MIMO antennas to the number of users on the performance of NS-based MIA. In addition, we derive the approximation error estimation formulas for different practical numbers of terms of NS-based MIA. These results could offer useful guidelines for practical massive MIMO systems.

cs.IT

Power Allocation for Precoding in Large-Scale MIMO Systems with Per-Antenna Constraint

Large-scale MIMO systems have been considered as one of the possible candidates for the next-generation wireless communication technique, due to their potential to provide significant higher throughput than conventional wireless systems. For such systems, Zero-Forcing (ZF) and Conjugate Beamforming (CB) precoding have been considered as two possible practical spatial multiplexing techniques, and their average achievable sum rates have been derived on the sum power constraint. However, in practice, the transmitting power at a base station is constrained under each antenna. In this case, the optimal power allocation is a very difficult problem. In this paper, the suboptimal power allocation methods for both ZF-based and CB-based precoding in large-scale MIMO systems under per-antenna constraint are investigated, which could provide useful references for practice.

cs.IT

Normalized Volume of Hyperball in Complex Grassmann Manifold and Its Application in Large-Scale MU-MIMO Communication Systems

This paper provides a solution to a critical issue in large-scale Multi-User Multiple-Input Multiple-Output (MU-MIMO) communication systems: how to estimate the Signal-to-Interference-plus-Noise-Ratios (SINRs) and their expectations in MU-MIMO mode at the Base Station (BS) side when only the Channel Quality Information (CQI) in Single-User MIMO (SU-MIMO) mode and non-ideal Channel State Information (CSI) are known? A solution to this problem would be very beneficial for the BS to predict the capacity of MU-MIMO and choose the proper modulation and channel coding for MU-MIMO. To that end, this paper derives a normalized volume formula of a hyperball based on the probability density function of the canonical angle between any two points in a complex Grassmann manifold, and shows that this formula provides a solution to the aforementioned issue. It enables the capability of a BS to predict the capacity loss due to non-ideal CSI, group users in MU-MIMO mode, choose the proper modulation and channel coding, and adaptively switch between SU-MIMO and MU-MIMO modes, as well as between Conjugate Beamforming (CB) and Zero-Forcing (ZF) precoding. Numerical results are provided to verify the validity and accuracy of the solution.

cs.IT

Small Cell In-Band Wireless Backhaul in Massive MIMO Systems: A Cooperation of Next-Generation Techniques

Massive multiple-inputmultiple-output (MIMO) systems, dense small-cells (SCs), and full duplex are three candidate techniques for next-generation communication systems. The cooperation of next-generation techniques could offer more benefits, e.g., SC in-band wireless backhaul in massive MIMO systems. In this paper, three strategies of SC in-band wireless backhaul in massive MIMO systems are introduced and compared, i.e., complete time-division duplex (CTDD), zero-division duplex (ZDD), and ZDD with interference rejection (ZDD-IR). Simulation results demonstrate that SC in-band wireless backhaul has the potential to improve the throughput for massive MIMO systems. Specifically, among the three strategies, CTDD is the simplest one and could achieve decent throughput improvement. Depending on conditions, with the self-interference cancellation capability at SCs, ZDD could achieve better throughput than CTDD, even with residual self-interference. Moreover, ZDD-IR requires the additional interference rejection process at the BS compared to ZDD, but it could generally achieve better throughput than CTDD and ZDD.

cs.IT

Inference with Possibilistic Evidence

In this paper, the concept of possibilistic evidence which is a possibility distribution as well as a body of evidence is proposed over an infinite universe of discourse. The inference with possibilistic evidence is investigated based on a unified inference framework maintaining both the compatibility of concepts and the consistency of the probability logic.

cs.AI